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The map label for this gene is hslV [H]

Identifier: 85372870

GI number: 85372870

Start: 51465

End: 52022

Strand: Direct

Name: hslV [H]

Synonym: ELI_00215

Alternate gene names: 85372870

Gene position: 51465-52022 (Clockwise)

Preceding gene: 85372869

Following gene: 85372871

Centisome position: 1.69

GC content: 60.75

Gene sequence:

>558_bases
ATGGACACATCTTTAAACGCCCACGGCCTCACGCAATGGCACGGCACCACCATCATCGGCGTCAAGCGCGGCGACAAGAT
CGTCGTCGCGGGTGACGGCCAGGTCTCGATGGGCAACACCGTGATGAAGCCCAATGCCAAGAAGGTGCGTCGGATCGGTG
AGGGCAAGGTCGTGGCTGGCTTCGCCGGTGCTACGGCCGATGCGTTCACGCTCTTCGAGCGGCTGGAACGCAAGCTGGAC
CAATATTCGGGTCAGTTGATGCGCGCTGCTGTCGAGCTCGCCAAGGATTGGCGCACCGACAAGTACCTGCGCAATCTAGA
AGCGTTGATGATCGTCGCCGACAAGGAAACTTTGCTGGTTCTGACCGGAAACGGCGATGTGCTTGAGCCGGAAGGTGGTA
TCGCCGCGATCGGGTCGGGGGGGAACTATGCCCTCGCTGCTGCGCGCGCCCTTTCCGACTACGAAGACGATGCCGAACAG
ATCGCCCGCAAGGCCATGGCCGTCGCGGCAGAAATATGCGTTTTCACCAACGGCAGCGTCACGCTCGAAACCGTTTAA

Upstream 100 bases:

>100_bases
TCGGTGCACCGGGTGCCGGGGCCCCGGGTGGACCGGGGCGTTAGGTTCCGTTCCACCAGCCTGACTTGACCCCGCCACGC
CGCGCCCCATATCGCGCGGC

Downstream 100 bases:

>100_bases
TTTGCCGTCATCCCAGCGAACGCTGGGATCTGCTTCCACTTGTGAAGCGCCCGATTGACAGAGATCCCAGCGTTCGCTGG
GATGACGAGAGTAAATGACC

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MDTSLNAHGLTQWHGTTIIGVKRGDKIVVAGDGQVSMGNTVMKPNAKKVRRIGEGKVVAGFAGATADAFTLFERLERKLD
QYSGQLMRAAVELAKDWRTDKYLRNLEALMIVADKETLLVLTGNGDVLEPEGGIAAIGSGGNYALAAARALSDYEDDAEQ
IARKAMAVAAEICVFTNGSVTLETV

Sequences:

>Translated_185_residues
MDTSLNAHGLTQWHGTTIIGVKRGDKIVVAGDGQVSMGNTVMKPNAKKVRRIGEGKVVAGFAGATADAFTLFERLERKLD
QYSGQLMRAAVELAKDWRTDKYLRNLEALMIVADKETLLVLTGNGDVLEPEGGIAAIGSGGNYALAAARALSDYEDDAEQ
IARKAMAVAAEICVFTNGSVTLETV
>Mature_185_residues
MDTSLNAHGLTQWHGTTIIGVKRGDKIVVAGDGQVSMGNTVMKPNAKKVRRIGEGKVVAGFAGATADAFTLFERLERKLD
QYSGQLMRAAVELAKDWRTDKYLRNLEALMIVADKETLLVLTGNGDVLEPEGGIAAIGSGGNYALAAARALSDYEDDAEQ
IARKAMAVAAEICVFTNGSVTLETV

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery [H]

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790367, Length=169, Percent_Identity=60.3550295857988, Blast_Score=206, Evalue=1e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022281
- InterPro:   IPR001353 [H]

Pfam domain/function: PF00227 Proteasome [H]

EC number: 3.4.25.-

Molecular weight: Translated: 19687; Mature: 19687

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTSLNAHGLTQWHGTTIIGVKRGDKIVVAGDGQVSMGNTVMKPNAKKVRRIGEGKVVAG
CCCCCCCCCCEEECCEEEEEEECCCEEEEECCCCEECCCEEECCCHHHHHHCCCCCEEEE
FAGATADAFTLFERLERKLDQYSGQLMRAAVELAKDWRTDKYLRNLEALMIVADKETLLV
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCEEEEEEECCCEEEE
LTGNGDVLEPEGGIAAIGSGGNYALAAARALSDYEDDAEQIARKAMAVAAEICVFTNGSV
EECCCCEECCCCCEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEECCEE
TLETV
EEEEC
>Mature Secondary Structure
MDTSLNAHGLTQWHGTTIIGVKRGDKIVVAGDGQVSMGNTVMKPNAKKVRRIGEGKVVAG
CCCCCCCCCCEEECCEEEEEEECCCEEEEECCCCEECCCEEECCCHHHHHHCCCCCEEEE
FAGATADAFTLFERLERKLDQYSGQLMRAAVELAKDWRTDKYLRNLEALMIVADKETLLV
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCEEEEEEECCCEEEE
LTGNGDVLEPEGGIAAIGSGGNYALAAARALSDYEDDAEQIARKAMAVAAEICVFTNGSV
EECCCCEECCCCCEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEECCEE
TLETV
EEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA