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The map label for this gene is corA

Identifier: 85060319

GI number: 85060319

Start: 4018378

End: 4019328

Strand: Reverse

Name: corA

Synonym: SG2341

Alternate gene names: 85060319

Gene position: 4019328-4018378 (Counterclockwise)

Preceding gene: 85060320

Following gene: 85060316

Centisome position: 96.36

GC content: 55.73

Gene sequence:

>951_bases
ATGCTTAACGCATTTCAACTGGAAAACCATCGTTTGTCGCGTCTTGACGCTGATGAGCAGGGCACCTTACTTGATGCGGT
ATGGGTGGATCTCATCGAGCCCGGCGATGACGAGCGCGAACGGGTGCAGCACGAGCTAGGGCAGAGCCTAGCGACGCGTC
TGGAGCTAGAGGACATCGAAGCGTCCGCCCGCTTTTTCGAGGACGAGGACGGGCTGCATATTCATTCCTTCTTCTTTTAT
GCCGACGCTGAAGATCACGCCGGTAACGCCACTGTGGCATTTACTATCCGCGACGGTCGGCTTTATACCCTGCGCGAGCG
TGAACTGCCGGCGTTTCGCCTGTACCGGATGCGAACCCGCAGCCAGACGCTGATTGACGGCAACGTCTACGAGCTGCTGC
TGGATTTGTTCGAGACGAAAATCGAGCAACTGGCGGATGAAATTGAAAATATTTATAGCGATCTGGAAGCGCTGAGCCTG
GTCATCATGGATGGCCACCAGGGCGATGAGTATGATAACGCGCTCTCCACGCTCGCCGAGCTTGAGGACGTGGGTTGGAA
AGTCAGGCTGTGCCTGATGGATACCCAGCGTGCACTGAACTTTCTGGTGCGCAAGGCGCGGCTGCCGTCGGGGCAGCTGG
AGCAGGCGCGGGAGGTGCTGCGCGATATCGAGTCGTTGCTGCCCCATAACGAATCGTTGTTCCAGAAGGTGAACTTCCTG
ATGCAGGCGGCAATGGGATTTATCAATATCGAGCAGAACCGCATCATCAAGATATTCTCGGTGGTCTCGGTGGTTTTCCT
GCCGCCGACCTTGGTTGCCTCCAGTTATGGTATGAACTTCGAGTTTATGCCCGAGCTCAGATGGTCTTTCGGCTATCCGG
GCGCCATTATGCTGATGATTTTGGCCGGGCTGGCGCCGTATTTGTATTTCAAGCGCAAAAACTGGCTGTAG

Upstream 100 bases:

>100_bases
GTCGGTCTTTGACGGTCTGAAACTCGACGGTGGCTCCTCACCCCGTATTTCTGTGATCTAATGCGTTTCCCGTTGGTTAC
CGTGAAGGAAACGAGGGCGT

Downstream 100 bases:

>100_bases
GGAGTGGCGGAGGAGACGACGACGGCGGCCGGTCAGGGCGCCGATCCGGACGCAGGATATTTTCCCTCCGCGGCCGCAAT
GTGATAAAATGGCTACCTAC

Product: magnesium/nickel/cobalt transporter CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MLNAFQLENHRLSRLDADEQGTLLDAVWVDLIEPGDDERERVQHELGQSLATRLELEDIEASARFFEDEDGLHIHSFFFY
ADAEDHAGNATVAFTIRDGRLYTLRERELPAFRLYRMRTRSQTLIDGNVYELLLDLFETKIEQLADEIENIYSDLEALSL
VIMDGHQGDEYDNALSTLAELEDVGWKVRLCLMDTQRALNFLVRKARLPSGQLEQAREVLRDIESLLPHNESLFQKVNFL
MQAAMGFINIEQNRIIKIFSVVSVVFLPPTLVASSYGMNFEFMPELRWSFGYPGAIMLMILAGLAPYLYFKRKNWL

Sequences:

>Translated_316_residues
MLNAFQLENHRLSRLDADEQGTLLDAVWVDLIEPGDDERERVQHELGQSLATRLELEDIEASARFFEDEDGLHIHSFFFY
ADAEDHAGNATVAFTIRDGRLYTLRERELPAFRLYRMRTRSQTLIDGNVYELLLDLFETKIEQLADEIENIYSDLEALSL
VIMDGHQGDEYDNALSTLAELEDVGWKVRLCLMDTQRALNFLVRKARLPSGQLEQAREVLRDIESLLPHNESLFQKVNFL
MQAAMGFINIEQNRIIKIFSVVSVVFLPPTLVASSYGMNFEFMPELRWSFGYPGAIMLMILAGLAPYLYFKRKNWL
>Mature_316_residues
MLNAFQLENHRLSRLDADEQGTLLDAVWVDLIEPGDDERERVQHELGQSLATRLELEDIEASARFFEDEDGLHIHSFFFY
ADAEDHAGNATVAFTIRDGRLYTLRERELPAFRLYRMRTRSQTLIDGNVYELLLDLFETKIEQLADEIENIYSDLEALSL
VIMDGHQGDEYDNALSTLAELEDVGWKVRLCLMDTQRALNFLVRKARLPSGQLEQAREVLRDIESLLPHNESLFQKVNFL
MQAAMGFINIEQNRIIKIFSVVSVVFLPPTLVASSYGMNFEFMPELRWSFGYPGAIMLMILAGLAPYLYFKRKNWL

Specific function: Mediates influx of magnesium ions

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family

Homologues:

Organism=Escherichia coli, GI2367297, Length=316, Percent_Identity=88.2911392405063, Blast_Score=580, Evalue=1e-167,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CORA_SODGM (Q2NQF9)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_456021.1
- ProteinModelPortal:   Q2NQF9
- STRING:   Q2NQF9
- GeneID:   3867169
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG2341
- NMPDR:   fig|343509.6.peg.5084
- eggNOG:   COG0598
- HOGENOM:   HBG350378
- OMA:   TQGFINI
- PhylomeDB:   Q2NQF9
- ProtClustDB:   PRK11085
- BioCyc:   SGLO343509:SG2341-MONOMER
- InterPro:   IPR004488
- InterPro:   IPR002523
- PANTHER:   PTHR21535:SF1
- TIGRFAMs:   TIGR00383

Pfam domain/function: PF01544 CorA

EC number: NA

Molecular weight: Translated: 36508; Mature: 36508

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xf0cf91c)-; HASH(0x1098c000)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNAFQLENHRLSRLDADEQGTLLDAVWVDLIEPGDDERERVQHELGQSLATRLELEDIE
CCCCEECCCCHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ASARFFEDEDGLHIHSFFFYADAEDHAGNATVAFTIRDGRLYTLRERELPAFRLYRMRTR
HHHHHCCCCCCCEEEEEEEEECCCCCCCCEEEEEEEECCEEEEEECCCCCHHHHHHHHHC
SQTLIDGNVYELLLDLFETKIEQLADEIENIYSDLEALSLVIMDGHQGDEYDNALSTLAE
CCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHH
LEDVGWKVRLCLMDTQRALNFLVRKARLPSGQLEQAREVLRDIESLLPHNESLFQKVNFL
HHHCCCEEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
MQAAMGFINIEQNRIIKIFSVVSVVFLPPTLVASSYGMNFEFMPELRWSFGYPGAIMLMI
HHHHHHHEECCCCHHHHHHHHHHHHHCCHHHHHHHCCCCEEECCCHHCCCCCCHHHHHHH
LAGLAPYLYFKRKNWL
HHHHHHHHHHHCCCCH
>Mature Secondary Structure
MLNAFQLENHRLSRLDADEQGTLLDAVWVDLIEPGDDERERVQHELGQSLATRLELEDIE
CCCCEECCCCHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ASARFFEDEDGLHIHSFFFYADAEDHAGNATVAFTIRDGRLYTLRERELPAFRLYRMRTR
HHHHHCCCCCCCEEEEEEEEECCCCCCCCEEEEEEEECCEEEEEECCCCCHHHHHHHHHC
SQTLIDGNVYELLLDLFETKIEQLADEIENIYSDLEALSLVIMDGHQGDEYDNALSTLAE
CCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHH
LEDVGWKVRLCLMDTQRALNFLVRKARLPSGQLEQAREVLRDIESLLPHNESLFQKVNFL
HHHCCCEEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
MQAAMGFINIEQNRIIKIFSVVSVVFLPPTLVASSYGMNFEFMPELRWSFGYPGAIMLMI
HHHHHHHEECCCCHHHHHHHHHHHHHCCHHHHHHHCCCCEEECCCHHCCCCCCHHHHHHH
LAGLAPYLYFKRKNWL
HHHHHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA