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The map label for this gene is prgK [H]

Identifier: 85060054

GI number: 85060054

Start: 3583901

End: 3584662

Strand: Reverse

Name: prgK [H]

Synonym: SG2076

Alternate gene names: 85060054

Gene position: 3584662-3583901 (Counterclockwise)

Preceding gene: 85060055

Following gene: 85060053

Centisome position: 85.94

GC content: 60.1

Gene sequence:

>762_bases
ATGAGCAGTTCCAGACGCCTGGCGTGCGGCGCTATGATGATCGCCATGCTGAGCGCTTGCAAAGAGGAGCCGTTGCTCAA
AGGCCTCGATCAGGTACAGGCGAACGAGGTCATCACTACGCTGCAGCGCAACAATATCGCCGCCGAGAAAGCGGATCACG
GTAAAAGCGGTTACAGCGTTGCCATTAACAAGGTCGATTTACCGGCGGCGGTAGATCTGTTGAGAACCTATCAGGTGCCT
TCGCCGCCCCGCATGGAAATCGCACAGATGTTTCCAGGCGACTCGCTGGTGTCATCACCGCGTGCTGAGAAGGCACGACT
TTACTCGGCCATCGAACAGCGTCTGGAACAGTCATTGCAGGTGCTTGAGGGTGTCGTCAACGCGCGCGTTCATGTCAGTT
ACGATATCGACGCCGGTGAGAACGGCAGGGCGCCCCGGCCGGTCCACCTTTCCGCGCTGGTCAGCTATGAGCCAGACAGC
GATCCAGCGTTGCTGATTGGCGACGTAAAACGCTTTCTGAAAAACAGCTTTGCTGAGGTGGCCTATGAGCATATTTCGGT
GGTCCTCTCCCGCCGCCCGGCGCCGCAGCATTCGCCGCCGGTGCGTCATTTGCCGCCCGCGGCGGCATCGCTGTCCGGTT
GGCGGTTGGGGGCCATTGTGGCTGGTCTGGCCTTGCTGTTGTCGGTCGGATTATGGTGGCGGAAAAAACGGGCCGCGCCC
TTGCCCGCGCGCGCGATAAGTGATGAGTGTCGTGCCCCTTGA

Upstream 100 bases:

>100_bases
TGCAGCAGCAAATCAAGGGCATGAAATACGCCGTATCCACCTCGCTGACAGCGACGCTGGTCAATAAACTCACTTTGGCG
GTGAAGACCGTGCTAGGCGC

Downstream 100 bases:

>100_bases
TAGCGTCATGTTCGATCCGTTGACGTGGATCCATCCGTCCCGTTTTGCGCTGCCCGCCAGTCTGGACGGCATCGCGCAGC
GCTCGATAGTTAACGATATG

Product: type III secretion apparatus

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MSSSRRLACGAMMIAMLSACKEEPLLKGLDQVQANEVITTLQRNNIAAEKADHGKSGYSVAINKVDLPAAVDLLRTYQVP
SPPRMEIAQMFPGDSLVSSPRAEKARLYSAIEQRLEQSLQVLEGVVNARVHVSYDIDAGENGRAPRPVHLSALVSYEPDS
DPALLIGDVKRFLKNSFAEVAYEHISVVLSRRPAPQHSPPVRHLPPAAASLSGWRLGAIVAGLALLLSVGLWWRKKRAAP
LPARAISDECRAP

Sequences:

>Translated_253_residues
MSSSRRLACGAMMIAMLSACKEEPLLKGLDQVQANEVITTLQRNNIAAEKADHGKSGYSVAINKVDLPAAVDLLRTYQVP
SPPRMEIAQMFPGDSLVSSPRAEKARLYSAIEQRLEQSLQVLEGVVNARVHVSYDIDAGENGRAPRPVHLSALVSYEPDS
DPALLIGDVKRFLKNSFAEVAYEHISVVLSRRPAPQHSPPVRHLPPAAASLSGWRLGAIVAGLALLLSVGLWWRKKRAAP
LPARAISDECRAP
>Mature_252_residues
SSSRRLACGAMMIAMLSACKEEPLLKGLDQVQANEVITTLQRNNIAAEKADHGKSGYSVAINKVDLPAAVDLLRTYQVPS
PPRMEIAQMFPGDSLVSSPRAEKARLYSAIEQRLEQSLQVLEGVVNARVHVSYDIDAGENGRAPRPVHLSALVSYEPDSD
PALLIGDVKRFLKNSFAEVAYEHISVVLSRRPAPQHSPPVRHLPPAAASLSGWRLGAIVAGLALLLSVGLWWRKKRAAPL
PARAISDECRAP

Specific function: Required for invasion of epithelial cells. Could be involved in protein secretion [H]

COG id: COG4669

COG function: function code U; Type III secretory pathway, lipoprotein EscJ

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the yscJ lipoprotein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003282
- InterPro:   IPR006182 [H]

Pfam domain/function: PF01514 YscJ_FliF [H]

EC number: NA

Molecular weight: Translated: 27450; Mature: 27319

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSRRLACGAMMIAMLSACKEEPLLKGLDQVQANEVITTLQRNNIAAEKADHGKSGYSV
CCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCEE
AINKVDLPAAVDLLRTYQVPSPPRMEIAQMFPGDSLVSSPRAEKARLYSAIEQRLEQSLQ
EEECCCCHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHH
VLEGVVNARVHVSYDIDAGENGRAPRPVHLSALVSYEPDSDPALLIGDVKRFLKNSFAEV
HHHHHHCCEEEEEEECCCCCCCCCCCCEEEEEEEEECCCCCCEEHHHHHHHHHHHHHHHH
AYEHISVVLSRRPAPQHSPPVRHLPPAAASLSGWRLGAIVAGLALLLSVGLWWRKKRAAP
HHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
LPARAISDECRAP
CCHHHHHHHCCCC
>Mature Secondary Structure 
SSSRRLACGAMMIAMLSACKEEPLLKGLDQVQANEVITTLQRNNIAAEKADHGKSGYSV
CCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCEE
AINKVDLPAAVDLLRTYQVPSPPRMEIAQMFPGDSLVSSPRAEKARLYSAIEQRLEQSLQ
EEECCCCHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHH
VLEGVVNARVHVSYDIDAGENGRAPRPVHLSALVSYEPDSDPALLIGDVKRFLKNSFAEV
HHHHHHCCEEEEEEECCCCCCCCCCCCEEEEEEEEECCCCCCEEHHHHHHHHHHHHHHHH
AYEHISVVLSRRPAPQHSPPVRHLPPAAASLSGWRLGAIVAGLALLLSVGLWWRKKRAAP
HHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
LPARAISDECRAP
CCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7476203; 11677609 [H]