Click here to switch to the map view.

The map label for this gene is rlmM

Identifier: 85059932

GI number: 85059932

Start: 3363201

End: 3364301

Strand: Reverse

Name: rlmM

Synonym: SG1954

Alternate gene names: 85059932

Gene position: 3364301-3363201 (Counterclockwise)

Preceding gene: 85059933

Following gene: 85059927

Centisome position: 80.66

GC content: 57.77

Gene sequence:

>1101_bases
GTGAATAACGTTATTTTGTATTGCCGCCCCGGCTTTGAGAAAGAGTGCTCTGCTGAGGTTACCGAAAAGGCCGCCGCACG
GGAAATTTTTGGTTTCGCGCGTGTTAAGGATAACAGCGGGTACGTGGTGTTTGTCTGTTATCAGCATGAAGAGGCCGACC
GGCTGGTGCGCGTTTTGCCGCTGCGCAGCTTGATTTTTGCGCGCCAGATGATATTGGTGGGGGAGTTGCTGCGCGATCTC
CCTGCCGAGGATCGCATCACGCAGATAGCCGGTATGCTGACGGGCGCTGTCGCTGGCGCGGGTGAAGTGCGGGTTGAAGT
ACCCGATACCAATGAAAGCAAAGAGCTGATGAAATTCTGCCGCAAATTAACCGTGCCGCTGCGGGCCGCCTTGCGCGCAC
AACGGATTCTCAAGGGGGAGGAACACAGGTCGCCGCAGGTTATCCACGTACTGTTCATCGCGCCTGGATGTTGCTATGCG
GGCTACTCTTATCGTGATAATCATTCCCCGTTCTATATGGGCATTCCCCGGCTGAGATTTCCGCCCGATGCGCCCAGTCG
CTCCATGCTGAAACTGGAGGAAGCTTTCCACGTTTTCATTCCTGCCGATGAGTGGGATGAGCGCCTGGGTAGCGGTATGT
ATGCGGTAGATCTGGGCGCCTGTCCCGGCGGCTGGACTTACCAGTTGGTCAAACGCAGCATGATGGTGCATGCAGTGGAT
AATGGCACGATGGATGAGGCGCTGATGGCGACAGGGCAGGTGATCCATCATCGGGCGGACGGTTTCCGTTTCGAGCCGCC
GCGCAATAATGTCTACTGGCTGGTGTGTGATATGGTGGAAAAACCCTCCCGCGTGGCGCAGTTGGCCGCGGATTGGCTGG
TGAAGGGGTGGTGCCGCGAGGCCATTTTCAACCTGAAGCTGCCGATGAAAAAGCGCTATGAAGAGGTTAGCCAGAACTTG
CGCCTGCTCATCGACCATCTTCAGGTGAATGGCGTGCATGGGGAAGTGCACGCCAAGCAACTCTACCATGACCGGGAGGA
GGTCACGGTGCACGCCCGCCGGTTCTGGAGCGCGGTGCCGGGACGGCGCGATGAACGCTGA

Upstream 100 bases:

>100_bases
CTGTGGGTTTATATCACGCCCATCGGTGGCGTGTGTTTCCTGACGGGCTGGATATTGCTGCTGATTGGCGCGCTGCGTCT
GAAAAAAAAGGCCGAACGCC

Downstream 100 bases:

>100_bases
CGGCGCGTCGCGGGTCTGAATTTGCGCACGGTCGCACGCCAGACAATGTGCCGGTTACCTTTGGATCGGGGCATTCTCTG
CGCAACGCCGCGCGCCTGCC

Product: putative RNA 2'-O-ribose methyltransferase

Products: NA

Alternate protein names: 23S rRNA 2'-O-ribose methyltransferase rlmM

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MNNVILYCRPGFEKECSAEVTEKAAAREIFGFARVKDNSGYVVFVCYQHEEADRLVRVLPLRSLIFARQMILVGELLRDL
PAEDRITQIAGMLTGAVAGAGEVRVEVPDTNESKELMKFCRKLTVPLRAALRAQRILKGEEHRSPQVIHVLFIAPGCCYA
GYSYRDNHSPFYMGIPRLRFPPDAPSRSMLKLEEAFHVFIPADEWDERLGSGMYAVDLGACPGGWTYQLVKRSMMVHAVD
NGTMDEALMATGQVIHHRADGFRFEPPRNNVYWLVCDMVEKPSRVAQLAADWLVKGWCREAIFNLKLPMKKRYEEVSQNL
RLLIDHLQVNGVHGEVHAKQLYHDREEVTVHARRFWSAVPGRRDER

Sequences:

>Translated_366_residues
MNNVILYCRPGFEKECSAEVTEKAAAREIFGFARVKDNSGYVVFVCYQHEEADRLVRVLPLRSLIFARQMILVGELLRDL
PAEDRITQIAGMLTGAVAGAGEVRVEVPDTNESKELMKFCRKLTVPLRAALRAQRILKGEEHRSPQVIHVLFIAPGCCYA
GYSYRDNHSPFYMGIPRLRFPPDAPSRSMLKLEEAFHVFIPADEWDERLGSGMYAVDLGACPGGWTYQLVKRSMMVHAVD
NGTMDEALMATGQVIHHRADGFRFEPPRNNVYWLVCDMVEKPSRVAQLAADWLVKGWCREAIFNLKLPMKKRYEEVSQNL
RLLIDHLQVNGVHGEVHAKQLYHDREEVTVHARRFWSAVPGRRDER
>Mature_366_residues
MNNVILYCRPGFEKECSAEVTEKAAAREIFGFARVKDNSGYVVFVCYQHEEADRLVRVLPLRSLIFARQMILVGELLRDL
PAEDRITQIAGMLTGAVAGAGEVRVEVPDTNESKELMKFCRKLTVPLRAALRAQRILKGEEHRSPQVIHVLFIAPGCCYA
GYSYRDNHSPFYMGIPRLRFPPDAPSRSMLKLEEAFHVFIPADEWDERLGSGMYAVDLGACPGGWTYQLVKRSMMVHAVD
NGTMDEALMATGQVIHHRADGFRFEPPRNNVYWLVCDMVEKPSRVAQLAADWLVKGWCREAIFNLKLPMKKRYEEVSQNL
RLLIDHLQVNGVHGEVHAKQLYHDREEVTVHARRFWSAVPGRRDER

Specific function: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA

COG id: COG2933

COG function: function code R; Predicted SAM-dependent methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmE family. RlmM subfamily

Homologues:

Organism=Escherichia coli, GI1789171, Length=366, Percent_Identity=69.672131147541, Blast_Score=548, Evalue=1e-157,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RLMM_SODGM (Q2NRJ6)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_455634.1
- ProteinModelPortal:   Q2NRJ6
- SMR:   Q2NRJ6
- STRING:   Q2NRJ6
- GeneID:   3866212
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG1954
- NMPDR:   fig|343509.6.peg.4216
- eggNOG:   COG2933
- HOGENOM:   HBG681972
- OMA:   LYCRPGF
- PhylomeDB:   Q2NRJ6
- ProtClustDB:   PRK11760
- BioCyc:   SGLO343509:SG1954-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01551
- InterPro:   IPR011224
- InterPro:   IPR002877
- PIRSF:   PIRSF028774

Pfam domain/function: PF01728 FtsJ

EC number: NA

Molecular weight: Translated: 41810; Mature: 41810

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNVILYCRPGFEKECSAEVTEKAAAREIFGFARVKDNSGYVVFVCYQHEEADRLVRVLP
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEEECCCCHHHHHHHHH
LRSLIFARQMILVGELLRDLPAEDRITQIAGMLTGAVAGAGEVRVEVPDTNESKELMKFC
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHH
RKLTVPLRAALRAQRILKGEEHRSPQVIHVLFIAPGCCYAGYSYRDNHSPFYMGIPRLRF
HHHCHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHCCCCCCCCCCCEEECCCCCCC
PPDAPSRSMLKLEEAFHVFIPADEWDERLGSGMYAVDLGACPGGWTYQLVKRSMMVHAVD
CCCCCCHHHHHHHCCEEEEECCCHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHEEEEC
NGTMDEALMATGQVIHHRADGFRFEPPRNNVYWLVCDMVEKPSRVAQLAADWLVKGWCRE
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECHHCHHHHHHHHHHHHHHHHHHH
AIFNLKLPMKKRYEEVSQNLRLLIDHLQVNGVHGEVHAKQLYHDREEVTVHARRFWSAVP
HHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCC
GRRDER
CCCCCC
>Mature Secondary Structure
MNNVILYCRPGFEKECSAEVTEKAAAREIFGFARVKDNSGYVVFVCYQHEEADRLVRVLP
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEEECCCCHHHHHHHHH
LRSLIFARQMILVGELLRDLPAEDRITQIAGMLTGAVAGAGEVRVEVPDTNESKELMKFC
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHH
RKLTVPLRAALRAQRILKGEEHRSPQVIHVLFIAPGCCYAGYSYRDNHSPFYMGIPRLRF
HHHCHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHCCCCCCCCCCCEEECCCCCCC
PPDAPSRSMLKLEEAFHVFIPADEWDERLGSGMYAVDLGACPGGWTYQLVKRSMMVHAVD
CCCCCCHHHHHHHCCEEEEECCCHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHEEEEC
NGTMDEALMATGQVIHHRADGFRFEPPRNNVYWLVCDMVEKPSRVAQLAADWLVKGWCRE
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECHHCHHHHHHHHHHHHHHHHHHH
AIFNLKLPMKKRYEEVSQNLRLLIDHLQVNGVHGEVHAKQLYHDREEVTVHARRFWSAVP
HHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCC
GRRDER
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA