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The map label for this gene is tsf

Identifier: 85059920

GI number: 85059920

Start: 3346636

End: 3347493

Strand: Reverse

Name: tsf

Synonym: SG1942

Alternate gene names: 85059920

Gene position: 3347493-3346636 (Counterclockwise)

Preceding gene: 85059921

Following gene: 85059919

Centisome position: 80.25

GC content: 56.29

Gene sequence:

>858_bases
ATGGCTGATATTACCGCCGCCCTGGTTAAAGAACTGCGCGAACGTACCGGCGCAGGCATGATGGAATGCAAAAAAGCGCT
GGTTGAAGCTCAGGGCGATATCGAACTGGCTATCGACAACATGCGTAAGTCCGGCCAGGCCAAAGCCGCCAAGAAAGCGG
GCCGTGTCGCGGCAGAAGGTGTCATTTTGACCAAAATCGCCCAAGACGGCAAATACGGCGTCATCATCGAGCTGAACTGT
GAAACCGATTTCGTTGCCAAAGACGGCGGCTTCAAAGCCTTTGGCGACGAGGTCATCACCGCCGCGCTGAACGAACGCAT
CACCGACGTAGAAGCGTTGAAGGCCAAATTTGAAGAACAGCGCACCGCGCTGGTAGCCAAAATTAGTGAAAACATCAATA
TCCGCCGCCTCGGCGTTCTGGAAGGCGGCGTGCTCGGTTCTTACCTGCACGGCGCGCGCATTGGTGTCATGGTTTCCGCC
GCCGGCGCCGACGAAGAGCTGGTGAAGCACGTCGCCATGCACATTGCCGCCAGCAAACCGGAATACGTCAATGCGGATGA
TGTACCTGCCGACGTAGTTGCCCGTGAGCATCAAATCCAGCTCGACATCGCCATGCAGTCCGGCAAACCGCGTGAAATCG
CCGAGAAGATGGTGGAAGGCCGTATGCGCAAGTTCACCGGCGAAATTTCTCTGACCGGCCAGCACTTCGTGATGGACCCG
AGCAAGACCGTTGGTCAGCTGCTGGGCGAACACGGTGCCAAAATCAACAACTTCATCCGTTTTGAAGTGGGCGAAGGCAT
TGAGAAAGCTGAAGTCGATTTCGCCGCCGAAGTGGCCGCGATGGGTAAGCAGTTTTAA

Upstream 100 bases:

>100_bases
GGAGCCCTTATTGACCAAGTTTTAAATATGTTGGTTAGAGGGCCTGTCATCAGTCCCTCTTTTTTACCTATCTCCAACAC
GGAATAACGAGGAAAAGATA

Downstream 100 bases:

>100_bases
TTAAGTTGTTCGGAACCGCCTGTAGGCGGTTCCGCTTTTAATGAGCCGGAATAATGTCAGACGACGTGTGCCGCACCAGG
TCAATTCCATCCCATCAAAT

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MADITAALVKELRERTGAGMMECKKALVEAQGDIELAIDNMRKSGQAKAAKKAGRVAAEGVILTKIAQDGKYGVIIELNC
ETDFVAKDGGFKAFGDEVITAALNERITDVEALKAKFEEQRTALVAKISENINIRRLGVLEGGVLGSYLHGARIGVMVSA
AGADEELVKHVAMHIAASKPEYVNADDVPADVVAREHQIQLDIAMQSGKPREIAEKMVEGRMRKFTGEISLTGQHFVMDP
SKTVGQLLGEHGAKINNFIRFEVGEGIEKAEVDFAAEVAAMGKQF

Sequences:

>Translated_285_residues
MADITAALVKELRERTGAGMMECKKALVEAQGDIELAIDNMRKSGQAKAAKKAGRVAAEGVILTKIAQDGKYGVIIELNC
ETDFVAKDGGFKAFGDEVITAALNERITDVEALKAKFEEQRTALVAKISENINIRRLGVLEGGVLGSYLHGARIGVMVSA
AGADEELVKHVAMHIAASKPEYVNADDVPADVVAREHQIQLDIAMQSGKPREIAEKMVEGRMRKFTGEISLTGQHFVMDP
SKTVGQLLGEHGAKINNFIRFEVGEGIEKAEVDFAAEVAAMGKQF
>Mature_284_residues
ADITAALVKELRERTGAGMMECKKALVEAQGDIELAIDNMRKSGQAKAAKKAGRVAAEGVILTKIAQDGKYGVIIELNCE
TDFVAKDGGFKAFGDEVITAALNERITDVEALKAKFEEQRTALVAKISENINIRRLGVLEGGVLGSYLHGARIGVMVSAA
GADEELVKHVAMHIAASKPEYVNADDVPADVVAREHQIQLDIAMQSGKPREIAEKMVEGRMRKFTGEISLTGQHFVMDPS
KTVGQLLGEHGAKINNFIRFEVGEGIEKAEVDFAAEVAAMGKQF

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI171846268, Length=288, Percent_Identity=27.7777777777778, Blast_Score=86, Evalue=5e-17,
Organism=Escherichia coli, GI1786366, Length=284, Percent_Identity=76.056338028169, Blast_Score=440, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI17561440, Length=295, Percent_Identity=25.7627118644068, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI19921466, Length=292, Percent_Identity=30.1369863013699, Blast_Score=90, Evalue=1e-18,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_SODGM (Q2NRK8)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_455622.1
- ProteinModelPortal:   Q2NRK8
- SMR:   Q2NRK8
- STRING:   Q2NRK8
- GeneID:   3867854
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG1942
- NMPDR:   fig|343509.6.peg.4196
- eggNOG:   COG0264
- HOGENOM:   HBG713289
- OMA:   YLHGTRI
- PhylomeDB:   Q2NRK8
- ProtClustDB:   PRK09377
- BioCyc:   SGLO343509:SG1942-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 30680; Mature: 30548

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADITAALVKELRERTGAGMMECKKALVEAQGDIELAIDNMRKSGQAKAAKKAGRVAAEG
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEHHHHCCCHHHHHHHHCCHHHCC
VILTKIAQDGKYGVIIELNCETDFVAKDGGFKAFGDEVITAALNERITDVEALKAKFEEQ
EEEEEECCCCCEEEEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTALVAKISENINIRRLGVLEGGVLGSYLHGARIGVMVSAAGADEELVKHVAMHIAASKP
HHHHHHHHHCCCCEEEEEEECCCHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHHHCCCC
EYVNADDVPADVVAREHQIQLDIAMQSGKPREIAEKMVEGRMRKFTGEISLTGQHFVMDP
CCCCCCCCCHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEECCCEEEECC
SKTVGQLLGEHGAKINNFIRFEVGEGIEKAEVDFAAEVAAMGKQF
HHHHHHHHHHCCCCHHHEEEEECCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ADITAALVKELRERTGAGMMECKKALVEAQGDIELAIDNMRKSGQAKAAKKAGRVAAEG
CCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEHHHHCCCHHHHHHHHCCHHHCC
VILTKIAQDGKYGVIIELNCETDFVAKDGGFKAFGDEVITAALNERITDVEALKAKFEEQ
EEEEEECCCCCEEEEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTALVAKISENINIRRLGVLEGGVLGSYLHGARIGVMVSAAGADEELVKHVAMHIAASKP
HHHHHHHHHCCCCEEEEEEECCCHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHHHCCCC
EYVNADDVPADVVAREHQIQLDIAMQSGKPREIAEKMVEGRMRKFTGEISLTGQHFVMDP
CCCCCCCCCHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEECCCEEEECC
SKTVGQLLGEHGAKINNFIRFEVGEGIEKAEVDFAAEVAAMGKQF
HHHHHHHHHHCCCCHHHEEEEECCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA