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The map label for this gene is mlaA [H]

Identifier: 85059610

GI number: 85059610

Start: 2790555

End: 2791313

Strand: Reverse

Name: mlaA [H]

Synonym: SG1632

Alternate gene names: 85059610

Gene position: 2791313-2790555 (Counterclockwise)

Preceding gene: 85059611

Following gene: 85059609

Centisome position: 66.92

GC content: 55.2

Gene sequence:

>759_bases
ATGAATTTTCGCCTGTCAGGTGTGGCGTTTGCCAGCGTCCTGCTTCTGGGGTGCGCTACTCATCAAAATCAGGACTACCA
GGGCCGGTCGGATCCTCTGGAAGGCTTTAACCGCAGCATGTTCAATTTTAACTACAACGTGCTGGATCCCTATGTAGTTC
GCCCGGCGGCGGTGGCCTGGCGAGATTATGTGCCGAAGCCGGCACGTAACTGTTTGAACAATTTCTTCACTAACCTCGAA
GAGCCCGCCACCATGGTCAACTATTTTGTAGAAGGGAAACCCTACAAGGCGATGGTGCATTTTAACCGCTTTTTCCTGAA
TACCTTGCTGGGGATGGGGGGCTTGATCGACGTGGCCTCGATGGCGAACCCGAAACTGGCCAAAGAGGAGCCGCGGCGTT
TCGGCAGTACTCTGGGTAATTATGGCGTCGGTTATGGTCCCTATGTGCAGCTCCCCGGCTACGGGAGTTTCACGCCTCGT
GAGGACATCGGCGGATTGGTAGATGATCTTTATCCACTCTTGAGCTATCTCACCTGGTGGATGTCCGCGGGCAAATGGGC
GTTGGAAGGACTGGAAACACGAGCGCAACTGCTGGACTCCGACGGCCTGCTGCAGAACTCGCAAGATCCTTACGCCATGG
TGCGCGCCGCCTATTTCCAGCGGCATGATTTCCTGGCCAGCGATGGCGTGTTGACACCGCAGGAGAATCCGAACGCCGAA
GCGATCCAAGGCGATCTCAATTCGATAGATGCTCAGTAA

Upstream 100 bases:

>100_bases
GAGTGCGACGCAGCCATTCGGCGGCAACGGCAGGGTAGCGGTTGAGATTAACCAGCAGCTCCCCTAGCGATGGCATAAGA
ATATACAACGGAGTTTTATA

Downstream 100 bases:

>100_bases
GCGACGGGCCGCGCCTGCCGCGTGCGGTCCTTGGGTCGCCGTCCTGCCGGCCCGGGGCGGCGGGGGGCATAGCCGCACAG
CCGGCCATGCGGCGTACCAT

Product: lipoprotein precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MNFRLSGVAFASVLLLGCATHQNQDYQGRSDPLEGFNRSMFNFNYNVLDPYVVRPAAVAWRDYVPKPARNCLNNFFTNLE
EPATMVNYFVEGKPYKAMVHFNRFFLNTLLGMGGLIDVASMANPKLAKEEPRRFGSTLGNYGVGYGPYVQLPGYGSFTPR
EDIGGLVDDLYPLLSYLTWWMSAGKWALEGLETRAQLLDSDGLLQNSQDPYAMVRAAYFQRHDFLASDGVLTPQENPNAE
AIQGDLNSIDAQ

Sequences:

>Translated_252_residues
MNFRLSGVAFASVLLLGCATHQNQDYQGRSDPLEGFNRSMFNFNYNVLDPYVVRPAAVAWRDYVPKPARNCLNNFFTNLE
EPATMVNYFVEGKPYKAMVHFNRFFLNTLLGMGGLIDVASMANPKLAKEEPRRFGSTLGNYGVGYGPYVQLPGYGSFTPR
EDIGGLVDDLYPLLSYLTWWMSAGKWALEGLETRAQLLDSDGLLQNSQDPYAMVRAAYFQRHDFLASDGVLTPQENPNAE
AIQGDLNSIDAQ
>Mature_252_residues
MNFRLSGVAFASVLLLGCATHQNQDYQGRSDPLEGFNRSMFNFNYNVLDPYVVRPAAVAWRDYVPKPARNCLNNFFTNLE
EPATMVNYFVEGKPYKAMVHFNRFFLNTLLGMGGLIDVASMANPKLAKEEPRRFGSTLGNYGVGYGPYVQLPGYGSFTPR
EDIGGLVDDLYPLLSYLTWWMSAGKWALEGLETRAQLLDSDGLLQNSQDPYAMVRAAYFQRHDFLASDGVLTPQENPNAE
AIQGDLNSIDAQ

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane [H]

COG id: COG2853

COG function: function code M; Surface lipoprotein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaA family [H]

Homologues:

Organism=Escherichia coli, GI1788688, Length=252, Percent_Identity=71.8253968253968, Blast_Score=382, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007428 [H]

Pfam domain/function: PF04333 VacJ [H]

EC number: NA

Molecular weight: Translated: 28181; Mature: 28181

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFRLSGVAFASVLLLGCATHQNQDYQGRSDPLEGFNRSMFNFNYNVLDPYVVRPAAVAW
CCEECHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCHHHHCCCCCCCCCHHHHHHHHHH
RDYVPKPARNCLNNFFTNLEEPATMVNYFVEGKPYKAMVHFNRFFLNTLLGMGGLIDVAS
HHCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCHHHHHH
MANPKLAKEEPRRFGSTLGNYGVGYGPYVQLPGYGSFTPREDIGGLVDDLYPLLSYLTWW
HCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
MSAGKWALEGLETRAQLLDSDGLLQNSQDPYAMVRAAYFQRHDFLASDGVLTPQENPNAE
HHCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEECCCCCCCHH
AIQGDLNSIDAQ
HHHCCHHHCCCC
>Mature Secondary Structure
MNFRLSGVAFASVLLLGCATHQNQDYQGRSDPLEGFNRSMFNFNYNVLDPYVVRPAAVAW
CCEECHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCHHHHCCCCCCCCCHHHHHHHHHH
RDYVPKPARNCLNNFFTNLEEPATMVNYFVEGKPYKAMVHFNRFFLNTLLGMGGLIDVAS
HHCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCHHHHHH
MANPKLAKEEPRRFGSTLGNYGVGYGPYVQLPGYGSFTPREDIGGLVDDLYPLLSYLTWW
HCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
MSAGKWALEGLETRAQLLDSDGLLQNSQDPYAMVRAAYFQRHDFLASDGVLTPQENPNAE
HHCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEECCCCCCCHH
AIQGDLNSIDAQ
HHHCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]