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The map label for this gene is sixA [H]

Identifier: 85059608

GI number: 85059608

Start: 2788950

End: 2789426

Strand: Reverse

Name: sixA [H]

Synonym: SG1630

Alternate gene names: 85059608

Gene position: 2789426-2788950 (Counterclockwise)

Preceding gene: 85059609

Following gene: 85059606

Centisome position: 66.87

GC content: 62.47

Gene sequence:

>477_bases
ATGCAAGTTCTAATTATGCGGCACGGCGATGCTGTTTCCGAGGCCGCGAGCGATGCGGAAAGACCCCTGACCGATCGGGG
CCGTGATGAATCCGGCCTGATGGCGCGCTGGCTTAGCGGCCAGGTGGCGGACATCGATCGGGTGTTGGTCAGTCCCTATC
TGCGTGCCCGGCAGACGCTTGATACCCTGCAGGCGTATCTGGTGTTGCCGGACGGCCATGAAGTCCTGCCGGAGCTGACG
CCGGGCGGGGACGCCGGGCTGGTAAGCTGCTACCTGCAGGCGCTGGCGAATGAGGGCTTAAACCGGGTACTGGTCATCTC
CCATCTGCCGTTGGTGGGTTATCTGGTGGCGGATTTATGCCCGGAAGAGCAGCCGCCGATGTTCGCCACTTCCGCCGTGG
CTGGTGTTGATCTGGACGCTGTCAGCGGCAAGTTACGCTGGCAGGTCGGACCGAACCAACTGCTGTCGAAAGTCTGA

Upstream 100 bases:

>100_bases
GCCACCGCGGGTGGAGGGTGGCACGACCCGTACGTCATCACGGCTGGGGGGAACTGCCCGGTCGATCTGACGCGATGTTC
CCCAACGACAACGGTGCATT

Downstream 100 bases:

>100_bases
GCGAGCCCAGCGGACGTCTTTACCGATGAACATCGAGCTCAGCCCATCCCGACATTGACGCCTAGCGCCAAATCACGTCT
ACCGCCGTGCAGCGTTTACG

Product: phosphohistidine phosphatase

Products: NA

Alternate protein names: RX6 [H]

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MQVLIMRHGDAVSEAASDAERPLTDRGRDESGLMARWLSGQVADIDRVLVSPYLRARQTLDTLQAYLVLPDGHEVLPELT
PGGDAGLVSCYLQALANEGLNRVLVISHLPLVGYLVADLCPEEQPPMFATSAVAGVDLDAVSGKLRWQVGPNQLLSKV

Sequences:

>Translated_158_residues
MQVLIMRHGDAVSEAASDAERPLTDRGRDESGLMARWLSGQVADIDRVLVSPYLRARQTLDTLQAYLVLPDGHEVLPELT
PGGDAGLVSCYLQALANEGLNRVLVISHLPLVGYLVADLCPEEQPPMFATSAVAGVDLDAVSGKLRWQVGPNQLLSKV
>Mature_158_residues
MQVLIMRHGDAVSEAASDAERPLTDRGRDESGLMARWLSGQVADIDRVLVSPYLRARQTLDTLQAYLVLPDGHEVLPELT
PGGDAGLVSCYLQALANEGLNRVLVISHLPLVGYLVADLCPEEQPPMFATSAVAGVDLDAVSGKLRWQVGPNQLLSKV

Specific function: Exhibits phosphohistidine phosphatase activity towards the HPt domain of the ArcB sensor involved in the multistep His- Asp phosphorelay [H]

COG id: COG2062

COG function: function code T; Phosphohistidine phosphatase SixA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sixA phosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1788681, Length=155, Percent_Identity=65.8064516129032, Blast_Score=200, Evalue=4e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR004449 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: 3.1.3.- [C]

Molecular weight: Translated: 17013; Mature: 17013

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVLIMRHGDAVSEAASDAERPLTDRGRDESGLMARWLSGQVADIDRVLVSPYLRARQTL
CEEEEEECCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
DTLQAYLVLPDGHEVLPELTPGGDAGLVSCYLQALANEGLNRVLVISHLPLVGYLVADLC
HHHHHEEECCCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEHHCHHHHHHHHHHC
PEEQPPMFATSAVAGVDLDAVSGKLRWQVGPNQLLSKV
CCCCCCCEEHHHHCCCCHHHCCCEEEEEECHHHHHHCC
>Mature Secondary Structure
MQVLIMRHGDAVSEAASDAERPLTDRGRDESGLMARWLSGQVADIDRVLVSPYLRARQTL
CEEEEEECCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
DTLQAYLVLPDGHEVLPELTPGGDAGLVSCYLQALANEGLNRVLVISHLPLVGYLVADLC
HHHHHEEECCCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEHHCHHHHHHHHHHC
PEEQPPMFATSAVAGVDLDAVSGKLRWQVGPNQLLSKV
CCCCCCCEEHHHHCCCCHHHCCCEEEEEECHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9489669; 9205837; 9278503 [H]