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The map label for this gene is aroC

Identifier: 85059605

GI number: 85059605

Start: 2785920

End: 2787005

Strand: Reverse

Name: aroC

Synonym: SG1627

Alternate gene names: 85059605

Gene position: 2787005-2785920 (Counterclockwise)

Preceding gene: 85059606

Following gene: 85059604

Centisome position: 66.82

GC content: 61.23

Gene sequence:

>1086_bases
ATGGCAGGGAACAGTATTGGACAATTTTTCCGCGTGACGACCTTCGGTGAATCCCACGGCTCGGCGCTGGGTGGGATCGT
CGATGGCGTGCCGCCGGGTATCCCCCTTTGCGAGGAAGATTTGCAGCACGATCTTGACCGCCGGCGGCCAGGGACATCGC
GTTATACGACGCAGCGGCGCGAGCCGGATCGTGTAAAAATCCTCTCCGGTGTGTTTGAGGGCGTCACGACCGGCACCAGT
ATCGGGCTGCTTATCGACAATACCGATCAACGCTCGCAGGATTACAGCGCCATCAAGGATTTCTACCGTCCCGGTCACGC
CGATTACACCTATGCTCAGAAGTATGGCCGACGCGACTACCGCGGCGGCGGCCGATCTTCGGCGCGTGAAACGGCGATGC
GCGTCGCCGCCGGCGCTATCGCCAAGAAATACCTGGCCCAGCAGTGCGGGGTGCGGGTCCGCGGTTATTTGGCGCAAATG
GGCGATATCCACTGCGAGCTGAAAGACTGGACGCAAGTGGAAAAAAACTCGTTCTTCTGCCCCGATGTCGACTGTCTGGA
GGCGTTGGATGCACTAATACACGATCTGAAAAAGGCGGGGGATTCCATCGGCGCCGGAGTGACGGTCGTGGCGGAAAATC
TGCCCGCCGGACTCGGCGAGCCGGTATTTGATCGCCTCGATGCCGATCTGGCCCATGCGCTGATGAGCATCAACGCGGTG
AAAGGAGTGGAAATCGGCGATGGCTTCGCGGTTATCGGCAAGCGCGGCAGCGAAAACCGAGACGAAATTACCCTCGAGGG
CTTTCAAAGCAATCACGCCGGCGGCATTCTCGGCGGAATCAGCAGCGGCCAGCCGGTTATCGCGCATCTTGCCCTGAAGC
CCACCTCCAGCATCATGGTGCCCGGCCGGACGGTAAACCGCAGCGGCGACGCGGTAGAGATGGTCACCCGCGGCCGGCAC
GATCCCTGCGTTGGGATCCGGGCGGTACCGATCGCCGAAGCTATGATGGCTATCGTGCTGATGGATCATTTCTTGCGCCA
GCGTGCGCAGTGCGCGGACGTCGTTGCAGCGGCGCCGATAAGGTGA

Upstream 100 bases:

>100_bases
GCGGTGATCTTTTCAAGCTCTATCGTGATTGAAACGCCCGATCAAGCCCCGTGCGGCGCAGGCGTGTCTCTTTTTTATCA
GGAATTGGTAAGGAGTCCCG

Downstream 100 bases:

>100_bases
TGGTAATGCGCAGAGTATTAATCGGTTGTCTGGCGCTGGCGGCATTATTTTGCGTGGGGGCCGCGCAGACGCCGTGGCAA
AAAATCGACCATCCGATCGC

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MAGNSIGQFFRVTTFGESHGSALGGIVDGVPPGIPLCEEDLQHDLDRRRPGTSRYTTQRREPDRVKILSGVFEGVTTGTS
IGLLIDNTDQRSQDYSAIKDFYRPGHADYTYAQKYGRRDYRGGGRSSARETAMRVAAGAIAKKYLAQQCGVRVRGYLAQM
GDIHCELKDWTQVEKNSFFCPDVDCLEALDALIHDLKKAGDSIGAGVTVVAENLPAGLGEPVFDRLDADLAHALMSINAV
KGVEIGDGFAVIGKRGSENRDEITLEGFQSNHAGGILGGISSGQPVIAHLALKPTSSIMVPGRTVNRSGDAVEMVTRGRH
DPCVGIRAVPIAEAMMAIVLMDHFLRQRAQCADVVAAAPIR

Sequences:

>Translated_361_residues
MAGNSIGQFFRVTTFGESHGSALGGIVDGVPPGIPLCEEDLQHDLDRRRPGTSRYTTQRREPDRVKILSGVFEGVTTGTS
IGLLIDNTDQRSQDYSAIKDFYRPGHADYTYAQKYGRRDYRGGGRSSARETAMRVAAGAIAKKYLAQQCGVRVRGYLAQM
GDIHCELKDWTQVEKNSFFCPDVDCLEALDALIHDLKKAGDSIGAGVTVVAENLPAGLGEPVFDRLDADLAHALMSINAV
KGVEIGDGFAVIGKRGSENRDEITLEGFQSNHAGGILGGISSGQPVIAHLALKPTSSIMVPGRTVNRSGDAVEMVTRGRH
DPCVGIRAVPIAEAMMAIVLMDHFLRQRAQCADVVAAAPIR
>Mature_360_residues
AGNSIGQFFRVTTFGESHGSALGGIVDGVPPGIPLCEEDLQHDLDRRRPGTSRYTTQRREPDRVKILSGVFEGVTTGTSI
GLLIDNTDQRSQDYSAIKDFYRPGHADYTYAQKYGRRDYRGGGRSSARETAMRVAAGAIAKKYLAQQCGVRVRGYLAQMG
DIHCELKDWTQVEKNSFFCPDVDCLEALDALIHDLKKAGDSIGAGVTVVAENLPAGLGEPVFDRLDADLAHALMSINAVK
GVEIGDGFAVIGKRGSENRDEITLEGFQSNHAGGILGGISSGQPVIAHLALKPTSSIMVPGRTVNRSGDAVEMVTRGRHD
PCVGIRAVPIAEAMMAIVLMDHFLRQRAQCADVVAAAPIR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=359, Percent_Identity=81.8941504178273, Blast_Score=582, Evalue=1e-168,
Organism=Saccharomyces cerevisiae, GI6321290, Length=367, Percent_Identity=44.4141689373297, Blast_Score=298, Evalue=1e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_SODGM (Q2NSH3)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_455307.1
- HSSP:   P63611
- ProteinModelPortal:   Q2NSH3
- SMR:   Q2NSH3
- STRING:   Q2NSH3
- GeneID:   3867150
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG1627
- NMPDR:   fig|343509.6.peg.3465
- eggNOG:   COG0082
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- PhylomeDB:   Q2NSH3
- ProtClustDB:   PRK05382
- BioCyc:   SGLO343509:SG1627-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 38793; Mature: 38662

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGNSIGQFFRVTTFGESHGSALGGIVDGVPPGIPLCEEDLQHDLDRRRPGTSRYTTQRR
CCCCCHHHEEEEEECCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
EPDRVKILSGVFEGVTTGTSIGLLIDNTDQRSQDYSAIKDFYRPGHADYTYAQKYGRRDY
CCHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCC
RGGGRSSARETAMRVAAGAIAKKYLAQQCGVRVRGYLAQMGDIHCELKDWTQVEKNSFFC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEEHHHHHHHHCCCCCC
PDVDCLEALDALIHDLKKAGDSIGAGVTVVAENLPAGLGEPVFDRLDADLAHALMSINAV
CCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGDGFAVIGKRGSENRDEITLEGFQSNHAGGILGGISSGQPVIAHLALKPTSSIMV
CCCEECCCEEEECCCCCCCCCCEEEECCCCCCCCCEEECCCCCCCEEEEEEECCCCCEEE
PGRTVNRSGDAVEMVTRGRHDPCVGIRAVPIAEAMMAIVLMDHFLRQRAQCADVVAAAPI
CCCCCCCCCCHHHHHHCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
R
C
>Mature Secondary Structure 
AGNSIGQFFRVTTFGESHGSALGGIVDGVPPGIPLCEEDLQHDLDRRRPGTSRYTTQRR
CCCCHHHEEEEEECCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
EPDRVKILSGVFEGVTTGTSIGLLIDNTDQRSQDYSAIKDFYRPGHADYTYAQKYGRRDY
CCHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCC
RGGGRSSARETAMRVAAGAIAKKYLAQQCGVRVRGYLAQMGDIHCELKDWTQVEKNSFFC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEEHHHHHHHHCCCCCC
PDVDCLEALDALIHDLKKAGDSIGAGVTVVAENLPAGLGEPVFDRLDADLAHALMSINAV
CCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGDGFAVIGKRGSENRDEITLEGFQSNHAGGILGGISSGQPVIAHLALKPTSSIMV
CCCEECCCEEEECCCCCCCCCCEEEECCCCCCCCCEEECCCCCCCEEEEEEECCCCCEEE
PGRTVNRSGDAVEMVTRGRHDPCVGIRAVPIAEAMMAIVLMDHFLRQRAQCADVVAAAPI
CCCCCCCCCCHHHHHHCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA