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The map label for this gene is chiA [H]

Identifier: 85059452

GI number: 85059452

Start: 2463765

End: 2465825

Strand: Reverse

Name: chiA [H]

Synonym: SG1474

Alternate gene names: 85059452

Gene position: 2465825-2463765 (Counterclockwise)

Preceding gene: 85059453

Following gene: 85059451

Centisome position: 59.12

GC content: 50.8

Gene sequence:

>2061_bases
ATGAGCAGTCAGTTAATTCAGAAAGACCAATATAGCGATGAGTCATATCAGTATGATGGTTTTGACCCTAAGACCAATGA
TTCGGCCTACAGCTATACCTCTGCCCGGGTGATGAAACGCGTTTATAATAAATACGACACCAAGAACAAACCAAAAGTGT
TTGGCTATTATACCGACTGGGGACAGTACGATGGCAGAGCATTATCATCGCCACCCTCCGGTAGCGTTGATGTCGGGAGT
CGTGGCCGCGGGGTCGATTTCTCGCAATTATCCCCGACCGCCTATGATAAAATTATTTTCGGATTTACCGGTATTGTCGG
CGATAAAGGTGCCAATCAGTATAAAATCGAGCAGGCCGCGGCGTGGACCGGGAAAAAGCAATATGAAATGACCATTCTGG
ATCCCTGGGGTGATTGTCAGGCTTACTTCAACAACGGTTTTTCAAGTTATAAAGATTTTGGCTTCGGTCCCGGCACTACA
TACAATGGCGGATCGCAGGAAGATTGCTTCAAAGAAAGTCACCCCAATCTGCAAGGGGTGCTGGGCGCCCTACTGGCTCT
GAAGAAAAAAGCGGCGCTGGCAGGGCATGATCTTGCGCTTTCTTTCAGCGTCGGCGGCTGGACGATGAGCGAAATCTTCC
ATGAAATGGTCAAAAGTGACCAGGCGATCAACACTTTCGTCAGCAGCATCGTTGATTTCTTTCAACGCTTCCCCAGCTTC
TCTGAAATCGATATTGACTGGGAATATCCGAATGCCGCAGGTGCCGGTAACCCCCATGGCCCTGAAGACGGTGCGAATTA
CCAAAAATTGATTGCTGCTCTGCGTCAGGCGTTTAATAGCCATAACCGGCAAGATATCAAAATCAGTATCGCTTCGTCCG
CCAATGTCGACGTCCTGCAACATTCCAATATCAAAGGGCTGTTAGCTGCCGGGTTATACGGTATCAACGTTATGACCTAT
GACTTCTTTGGTACGCCGTGGCACGAAGGATTGACGAATCACACCAATCTGTATAAAACTGAGCATTCCAGTTATAGCCT
GGAAGAGGCGGTGACCTATCTGCTAGAACAGGGGGTGGATCCGGACGTCATTAATGTGGGCTATGCTGGTTATTCCCGTA
GCGCCAAAGGTGCCGAAATCAGCTCTTTCTCGCCGCTGAAGGGCACCTATGAAGGTAATGACACCACCGTCGGCACGTTC
GAGTCAGGTTGTGTTGAATGGTATGACGTTCTTTATAACTATCTCGATTTGGAAAATAAATCAGGTCGCAATGGCTACCA
GGTTTATACCGATGATGTCGCCTGTGCCGACTATCTGTATAGCCCGACGGCGAAGGTTTTCCATTCCATTGATACACCGC
GTAGCGTCAGGGAAAAAGCCCGCTATGTGATTGAAAAAGGTCTTGGCGGTATTTTTACCTGGACCATCGATTACGACAAT
GGCTTGCTGGTCAACGCAGCGCGTGAAGGGTTGGGCTGTCCGATTGTTGATAAGGTCATCGATATGAGTCCATTCTATTT
CAAGGGGATTAATATCACTGGTGAGGATGAAGGCAAGCCGGATGAGCCGAATACCCCTGACAAACCAGCGGCAGCACCGG
TCGCCAAGGTTGAGATTAAAGCTTTCGCGGGCAGTTCGTTACTGTTCTGTGGTCAGCAGTCCGTCAATGCCGCCTGCTAT
GAATGGTCCGCCACCCAGGGGGCCGTCATCGCCGCGCCGCATGCCGAACAGACTGCGGTAGTGCTGCCTAACGTCAGCGT
GGATACCCTCATATCCATAACCCTCGCCGTGACGAACGAAAGCGGTGAGCGGGCAACCGCTGTTTTCGCGTTAACGGTTG
TTCCAAAGGATGACACGGACGAGCAGCCGGAAACGCCGGATGAACCGGAAACCCCTTCGCAATATCAGCAGTGGATAGCC
ACTCAGATCTACACCGAAGGCAACCTGGTTTCCCATAAAGGCGTCGATTATCGGGCCAACCATTGGAGTCAGGGGGATGA
GCCAGGTCTGTCTACCACCACCGGACAGTATGGTTTCCCGTGGTCGGTGCTGGTTGCCTGA

Upstream 100 bases:

>100_bases
TTATTCATAACGAGGAAGGTAGCTCATTCAAAAGGTGAACGTGGTTAGTTTTTAAAATTACATATCTCTTAAATCATAAT
AACTTTGTAAGGTAACTAAC

Downstream 100 bases:

>100_bases
TCCCATTGCGTTATACCGATTCGGGTGAACGTCGTCACCCACGTTGACTCTTATCGATGCATCCACCCGCCGTCAGACAC
GGCGGGTTTGTTACATCTGG

Product: exochitinase

Products: NA

Alternate protein names: CHI-A [H]

Number of amino acids: Translated: 686; Mature: 685

Protein sequence:

>686_residues
MSSQLIQKDQYSDESYQYDGFDPKTNDSAYSYTSARVMKRVYNKYDTKNKPKVFGYYTDWGQYDGRALSSPPSGSVDVGS
RGRGVDFSQLSPTAYDKIIFGFTGIVGDKGANQYKIEQAAAWTGKKQYEMTILDPWGDCQAYFNNGFSSYKDFGFGPGTT
YNGGSQEDCFKESHPNLQGVLGALLALKKKAALAGHDLALSFSVGGWTMSEIFHEMVKSDQAINTFVSSIVDFFQRFPSF
SEIDIDWEYPNAAGAGNPHGPEDGANYQKLIAALRQAFNSHNRQDIKISIASSANVDVLQHSNIKGLLAAGLYGINVMTY
DFFGTPWHEGLTNHTNLYKTEHSSYSLEEAVTYLLEQGVDPDVINVGYAGYSRSAKGAEISSFSPLKGTYEGNDTTVGTF
ESGCVEWYDVLYNYLDLENKSGRNGYQVYTDDVACADYLYSPTAKVFHSIDTPRSVREKARYVIEKGLGGIFTWTIDYDN
GLLVNAAREGLGCPIVDKVIDMSPFYFKGINITGEDEGKPDEPNTPDKPAAAPVAKVEIKAFAGSSLLFCGQQSVNAACY
EWSATQGAVIAAPHAEQTAVVLPNVSVDTLISITLAVTNESGERATAVFALTVVPKDDTDEQPETPDEPETPSQYQQWIA
TQIYTEGNLVSHKGVDYRANHWSQGDEPGLSTTTGQYGFPWSVLVA

Sequences:

>Translated_686_residues
MSSQLIQKDQYSDESYQYDGFDPKTNDSAYSYTSARVMKRVYNKYDTKNKPKVFGYYTDWGQYDGRALSSPPSGSVDVGS
RGRGVDFSQLSPTAYDKIIFGFTGIVGDKGANQYKIEQAAAWTGKKQYEMTILDPWGDCQAYFNNGFSSYKDFGFGPGTT
YNGGSQEDCFKESHPNLQGVLGALLALKKKAALAGHDLALSFSVGGWTMSEIFHEMVKSDQAINTFVSSIVDFFQRFPSF
SEIDIDWEYPNAAGAGNPHGPEDGANYQKLIAALRQAFNSHNRQDIKISIASSANVDVLQHSNIKGLLAAGLYGINVMTY
DFFGTPWHEGLTNHTNLYKTEHSSYSLEEAVTYLLEQGVDPDVINVGYAGYSRSAKGAEISSFSPLKGTYEGNDTTVGTF
ESGCVEWYDVLYNYLDLENKSGRNGYQVYTDDVACADYLYSPTAKVFHSIDTPRSVREKARYVIEKGLGGIFTWTIDYDN
GLLVNAAREGLGCPIVDKVIDMSPFYFKGINITGEDEGKPDEPNTPDKPAAAPVAKVEIKAFAGSSLLFCGQQSVNAACY
EWSATQGAVIAAPHAEQTAVVLPNVSVDTLISITLAVTNESGERATAVFALTVVPKDDTDEQPETPDEPETPSQYQQWIA
TQIYTEGNLVSHKGVDYRANHWSQGDEPGLSTTTGQYGFPWSVLVA
>Mature_685_residues
SSQLIQKDQYSDESYQYDGFDPKTNDSAYSYTSARVMKRVYNKYDTKNKPKVFGYYTDWGQYDGRALSSPPSGSVDVGSR
GRGVDFSQLSPTAYDKIIFGFTGIVGDKGANQYKIEQAAAWTGKKQYEMTILDPWGDCQAYFNNGFSSYKDFGFGPGTTY
NGGSQEDCFKESHPNLQGVLGALLALKKKAALAGHDLALSFSVGGWTMSEIFHEMVKSDQAINTFVSSIVDFFQRFPSFS
EIDIDWEYPNAAGAGNPHGPEDGANYQKLIAALRQAFNSHNRQDIKISIASSANVDVLQHSNIKGLLAAGLYGINVMTYD
FFGTPWHEGLTNHTNLYKTEHSSYSLEEAVTYLLEQGVDPDVINVGYAGYSRSAKGAEISSFSPLKGTYEGNDTTVGTFE
SGCVEWYDVLYNYLDLENKSGRNGYQVYTDDVACADYLYSPTAKVFHSIDTPRSVREKARYVIEKGLGGIFTWTIDYDNG
LLVNAAREGLGCPIVDKVIDMSPFYFKGINITGEDEGKPDEPNTPDKPAAAPVAKVEIKAFAGSSLLFCGQQSVNAACYE
WSATQGAVIAAPHAEQTAVVLPNVSVDTLISITLAVTNESGERATAVFALTVVPKDDTDEQPETPDEPETPSQYQQWIAT
QIYTEGNLVSHKGVDYRANHWSQGDEPGLSTTTGQYGFPWSVLVA

Specific function: Unknown

COG id: COG3325

COG function: function code G; Chitinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily [H]

Homologues:

Organism=Homo sapiens, GI4502809, Length=350, Percent_Identity=24.8571428571429, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI133893286, Length=302, Percent_Identity=24.8344370860927, Blast_Score=74, Evalue=7e-13,
Organism=Homo sapiens, GI42542398, Length=283, Percent_Identity=24.7349823321555, Blast_Score=68, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71995504, Length=320, Percent_Identity=26.875, Blast_Score=92, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17559362, Length=305, Percent_Identity=25.5737704918033, Blast_Score=90, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17563680, Length=305, Percent_Identity=25.5737704918033, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17531689, Length=305, Percent_Identity=25.9016393442623, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17551250, Length=307, Percent_Identity=26.7100977198697, Blast_Score=80, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6320579, Length=339, Percent_Identity=28.9085545722714, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI221330815, Length=320, Percent_Identity=27.8125, Blast_Score=100, Evalue=5e-21,
Organism=Drosophila melanogaster, GI21358195, Length=325, Percent_Identity=27.3846153846154, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI161077700, Length=331, Percent_Identity=27.7945619335347, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI221329807, Length=331, Percent_Identity=27.7945619335347, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24655584, Length=407, Percent_Identity=22.3587223587224, Blast_Score=82, Evalue=2e-15,
Organism=Drosophila melanogaster, GI116007452, Length=410, Percent_Identity=22.1951219512195, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI22024049, Length=303, Percent_Identity=24.4224422442244, Blast_Score=77, Evalue=6e-14,
Organism=Drosophila melanogaster, GI45550474, Length=316, Percent_Identity=25.9493670886076, Blast_Score=70, Evalue=7e-12,
Organism=Drosophila melanogaster, GI28573679, Length=311, Percent_Identity=25.7234726688103, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002126
- InterPro:   IPR003610
- InterPro:   IPR011583
- InterPro:   IPR013540
- InterPro:   IPR001223
- InterPro:   IPR001579
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR013783
- InterPro:   IPR014756
- InterPro:   IPR022409 [H]

Pfam domain/function: PF02839 CBM_5_12; PF08329 ChitinaseA_N; PF00704 Glyco_hydro_18 [H]

EC number: =3.2.1.14 [H]

Molecular weight: Translated: 75201; Mature: 75070

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSQLIQKDQYSDESYQYDGFDPKTNDSAYSYTSARVMKRVYNKYDTKNKPKVFGYYTDW
CCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
GQYDGRALSSPPSGSVDVGSRGRGVDFSQLSPTAYDKIIFGFTGIVGDKGANQYKIEQAA
CCCCCCCCCCCCCCCEECCCCCCCCCHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEHHHH
AWTGKKQYEMTILDPWGDCQAYFNNGFSSYKDFGFGPGTTYNGGSQEDCFKESHPNLQGV
HHCCCCEEEEEEECCCHHHHHHHCCCCHHHHHCCCCCCCCCCCCCHHHHHHHCCCCHHHH
LGALLALKKKAALAGHDLALSFSVGGWTMSEIFHEMVKSDQAINTFVSSIVDFFQRFPSF
HHHHHHHHHHHHHCCCCEEEEEEECCEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCC
SEIDIDWEYPNAAGAGNPHGPEDGANYQKLIAALRQAFNSHNRQDIKISIASSANVDVLQ
CEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEE
HSNIKGLLAAGLYGINVMTYDFFGTPWHEGLTNHTNLYKTEHSSYSLEEAVTYLLEQGVD
CCCCCHHHHHHEEEEEEEEEECCCCCHHHCCCCCCCEEEECCCCCCHHHHHHHHHHCCCC
PDVINVGYAGYSRSAKGAEISSFSPLKGTYEGNDTTVGTFESGCVEWYDVLYNYLDLENK
CCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCC
SGRNGYQVYTDDVACADYLYSPTAKVFHSIDTPRSVREKARYVIEKGLGGIFTWTIDYDN
CCCCCCEEEECCHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEEECCC
GLLVNAAREGLGCPIVDKVIDMSPFYFKGINITGEDEGKPDEPNTPDKPAAAPVAKVEIK
CEEEEECCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEE
AFAGSSLLFCGQQSVNAACYEWSATQGAVIAAPHAEQTAVVLPNVSVDTLISITLAVTNE
EECCCEEEEECCCCCCCEEEEECCCCCCEEECCCCCCCEEEECCCCHHHEEEEEEEEECC
SGERATAVFALTVVPKDDTDEQPETPDEPETPSQYQQWIATQIYTEGNLVSHKGVDYRAN
CCCCEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHEECCCEEECCCCCCCCC
HWSQGDEPGLSTTTGQYGFPWSVLVA
CCCCCCCCCCCCCCCCCCCCEEEEEC
>Mature Secondary Structure 
SSQLIQKDQYSDESYQYDGFDPKTNDSAYSYTSARVMKRVYNKYDTKNKPKVFGYYTDW
CCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
GQYDGRALSSPPSGSVDVGSRGRGVDFSQLSPTAYDKIIFGFTGIVGDKGANQYKIEQAA
CCCCCCCCCCCCCCCEECCCCCCCCCHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEHHHH
AWTGKKQYEMTILDPWGDCQAYFNNGFSSYKDFGFGPGTTYNGGSQEDCFKESHPNLQGV
HHCCCCEEEEEEECCCHHHHHHHCCCCHHHHHCCCCCCCCCCCCCHHHHHHHCCCCHHHH
LGALLALKKKAALAGHDLALSFSVGGWTMSEIFHEMVKSDQAINTFVSSIVDFFQRFPSF
HHHHHHHHHHHHHCCCCEEEEEEECCEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCC
SEIDIDWEYPNAAGAGNPHGPEDGANYQKLIAALRQAFNSHNRQDIKISIASSANVDVLQ
CEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEE
HSNIKGLLAAGLYGINVMTYDFFGTPWHEGLTNHTNLYKTEHSSYSLEEAVTYLLEQGVD
CCCCCHHHHHHEEEEEEEEEECCCCCHHHCCCCCCCEEEECCCCCCHHHHHHHHHHCCCC
PDVINVGYAGYSRSAKGAEISSFSPLKGTYEGNDTTVGTFESGCVEWYDVLYNYLDLENK
CCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCC
SGRNGYQVYTDDVACADYLYSPTAKVFHSIDTPRSVREKARYVIEKGLGGIFTWTIDYDN
CCCCCCEEEECCHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEEECCC
GLLVNAAREGLGCPIVDKVIDMSPFYFKGINITGEDEGKPDEPNTPDKPAAAPVAKVEIK
CEEEEECCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEE
AFAGSSLLFCGQQSVNAACYEWSATQGAVIAAPHAEQTAVVLPNVSVDTLISITLAVTNE
EECCCEEEEECCCCCCCEEEEECCCCCCEEECCCCCCCEEEECCCCHHHEEEEEEEEECC
SGERATAVFALTVVPKDDTDEQPETPDEPETPSQYQQWIATQIYTEGNLVSHKGVDYRAN
CCCCEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHEECCCEEECCCCCCCCC
HWSQGDEPGLSTTTGQYGFPWSVLVA
CCCCCCCCCCCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8416892; 1464065; 7764022 [H]