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The map label for this gene is argS

Identifier: 85059226

GI number: 85059226

Start: 2108895

End: 2110625

Strand: Reverse

Name: argS

Synonym: SG1248

Alternate gene names: 85059226

Gene position: 2110625-2108895 (Counterclockwise)

Preceding gene: 85059228

Following gene: 85059223

Centisome position: 50.6

GC content: 57.94

Gene sequence:

>1731_bases
GTGAACATCCACACTCTTCTCTCAGAAAAAATCCAGCAGGCGCTGGTGGCCGCAGGCGCGCCCGCCGACTGCGAAGCGCA
GGTGCGCCAATCAGCGAAGGCTCAGTTCGGCGACTATCAAGCCAATGGCGTCATGGCGATTGCCAAACAGCTCGGTCTGC
CGCCCCGCAAGCTGGCGGAAAACGTCGTCGGTTTGCTGAATTTGGACGGTATCGCCCGTAAAGTCGACATCGCGGGTCCC
GGTTTCATCAATATTTTTCTCGAGCCGAGCTGGTTGGCAAACCACCTTGCCGCGGCCCTTTCCTCTCCGCGACTGGGCAT
TGCAAGCGTCGCGTCGCAAACCATCGTGGTGGATTATTCCGCGCCCAACGTCGCCAAAGAAATGCATGTCGGCCACGTGC
GTTCTACCATCATCGGCGATGCCTCGGTGCGCACGCTGTCGTTTTTGGGCCATAACGTTATTCGGGCCAATCACGTAGGC
GACTGGGGAACGCAATTCGGCATGCTGATCGCCTATTTGGAAAAGGTACAGGACGGCGGCGAAGCGGAAATGCAGCTCTC
AAGCCTGGAGAGCTTCTACCGCGCCGCCAAGCAGCATTACGACGAGGATCCGGCGTTCGCCGAGCGCGCCCGCGGCTATG
TGGTGAAGCTTCAGGGCGGCGACGAGTATTGTCGACAAATGTGGCGCAAACTGGTGGATGTCACCATGGCACAGAATCAG
AAAACCTATAACCGGCTTAATGTGACGTTAACGCGTGCGGACGTCATGGGGGAAAGCCTGTACAACGACATGCTGCCCGG
TATCGTGGCGGATTTGAAAGCGAAAGGGCTGGCGGTGGAGAGCGAAGGCGCCACCGTGGTGTTCCTCGACGAATTCAAAA
ACAAAGAAGGCGAGCCCATGGGGGTGATCATCCAGAAAAAGGATGGCGCTTACCTGTATACCACCACCGATATCGCCTGC
GCCAAATACCGCTATGAGACGCTGAAGGCCGACCGGATTATCTACTATATCGATTCACGCCAGCATCAGCACCTGATGCT
GGCCTGGACTATCGTGCGCAAGGCCGGCTACGTCCCTGAATCGGTCCCACTCGAGCACCACATGTTCGGCATGATGCTGG
GCAAAGACGGCAAACCGTTTAAAACCCGCGCCGGCGGCACCATCAAGCTCACAGAGCTGCTGGACGAAGCGCTGGAACGC
GCCCGCCGTCTGGTTGCCGCCAAGAACCCCTCCATGGACGCCGGGGAGTTGGCAAGACTGGCGCAGGTGGTGGGGATCGG
CGCGGTAAAATACGCCGATTTATCGAAAAGCCGCACCACTGATTATGTTTTTGACTGGGACAATATGCTGAGTTTTGAGG
GTAACACAGCGCCCTATATGCAATATGCCTATACCCGTGTCGCCTCGATATTCAAACGCAGCGGCCAGGATGAGCAGCAG
CTCACCGGCGACATCCGCCTGGAGGCGGAACAGGAAACCCAGCTGGCGGTTCGTCTGTTGCAGTTGGAAGAGGCCATTGC
GACCGTGGCACGCGACGGCACGCCGCATGTGCTCTGTGCCTATCTGTATGATTTGGCCGTGCTGTTCTCCGCTTTCTACG
AACACTGCCCCATCCTGAATGCCGAGAATGCGGCGCTGCGCCAAAGCCGCCTGCAATTGGCGCTGCTTACCGCACGCACG
CTAAAAAAAGGGCTGGATCTGCTGGGTATTGAAACCGTGGAACGGATGTAG

Upstream 100 bases:

>100_bases
GATCTGACCACCGTGTCCGCCCGGTTACGGTGGCGTAGTCAGGTTGTCAGGGAATGTCAGCGCTCTGCCTGCCTCCCGCC
CATGCAATAAAGGTATTCCG

Downstream 100 bases:

>100_bases
CTGACTAAAACGTCCGAAGCGTTAAGCCGTTTGTCAGCCCAGCCCTGGCCAAGCCGCCGGTCCACCTGATGATGCGGACT
GTTTTTTTTGCTTATGCCAA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 576; Mature: 576

Protein sequence:

>576_residues
MNIHTLLSEKIQQALVAAGAPADCEAQVRQSAKAQFGDYQANGVMAIAKQLGLPPRKLAENVVGLLNLDGIARKVDIAGP
GFINIFLEPSWLANHLAAALSSPRLGIASVASQTIVVDYSAPNVAKEMHVGHVRSTIIGDASVRTLSFLGHNVIRANHVG
DWGTQFGMLIAYLEKVQDGGEAEMQLSSLESFYRAAKQHYDEDPAFAERARGYVVKLQGGDEYCRQMWRKLVDVTMAQNQ
KTYNRLNVTLTRADVMGESLYNDMLPGIVADLKAKGLAVESEGATVVFLDEFKNKEGEPMGVIIQKKDGAYLYTTTDIAC
AKYRYETLKADRIIYYIDSRQHQHLMLAWTIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRAGGTIKLTELLDEALER
ARRLVAAKNPSMDAGELARLAQVVGIGAVKYADLSKSRTTDYVFDWDNMLSFEGNTAPYMQYAYTRVASIFKRSGQDEQQ
LTGDIRLEAEQETQLAVRLLQLEEAIATVARDGTPHVLCAYLYDLAVLFSAFYEHCPILNAENAALRQSRLQLALLTART
LKKGLDLLGIETVERM

Sequences:

>Translated_576_residues
MNIHTLLSEKIQQALVAAGAPADCEAQVRQSAKAQFGDYQANGVMAIAKQLGLPPRKLAENVVGLLNLDGIARKVDIAGP
GFINIFLEPSWLANHLAAALSSPRLGIASVASQTIVVDYSAPNVAKEMHVGHVRSTIIGDASVRTLSFLGHNVIRANHVG
DWGTQFGMLIAYLEKVQDGGEAEMQLSSLESFYRAAKQHYDEDPAFAERARGYVVKLQGGDEYCRQMWRKLVDVTMAQNQ
KTYNRLNVTLTRADVMGESLYNDMLPGIVADLKAKGLAVESEGATVVFLDEFKNKEGEPMGVIIQKKDGAYLYTTTDIAC
AKYRYETLKADRIIYYIDSRQHQHLMLAWTIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRAGGTIKLTELLDEALER
ARRLVAAKNPSMDAGELARLAQVVGIGAVKYADLSKSRTTDYVFDWDNMLSFEGNTAPYMQYAYTRVASIFKRSGQDEQQ
LTGDIRLEAEQETQLAVRLLQLEEAIATVARDGTPHVLCAYLYDLAVLFSAFYEHCPILNAENAALRQSRLQLALLTART
LKKGLDLLGIETVERM
>Mature_576_residues
MNIHTLLSEKIQQALVAAGAPADCEAQVRQSAKAQFGDYQANGVMAIAKQLGLPPRKLAENVVGLLNLDGIARKVDIAGP
GFINIFLEPSWLANHLAAALSSPRLGIASVASQTIVVDYSAPNVAKEMHVGHVRSTIIGDASVRTLSFLGHNVIRANHVG
DWGTQFGMLIAYLEKVQDGGEAEMQLSSLESFYRAAKQHYDEDPAFAERARGYVVKLQGGDEYCRQMWRKLVDVTMAQNQ
KTYNRLNVTLTRADVMGESLYNDMLPGIVADLKAKGLAVESEGATVVFLDEFKNKEGEPMGVIIQKKDGAYLYTTTDIAC
AKYRYETLKADRIIYYIDSRQHQHLMLAWTIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRAGGTIKLTELLDEALER
ARRLVAAKNPSMDAGELARLAQVVGIGAVKYADLSKSRTTDYVFDWDNMLSFEGNTAPYMQYAYTRVASIFKRSGQDEQQ
LTGDIRLEAEQETQLAVRLLQLEEAIATVARDGTPHVLCAYLYDLAVLFSAFYEHCPILNAENAALRQSRLQLALLTART
LKKGLDLLGIETVERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=572, Percent_Identity=37.5874125874126, Blast_Score=370, Evalue=1e-102,
Organism=Homo sapiens, GI197100773, Length=478, Percent_Identity=29.0794979079498, Blast_Score=191, Evalue=1e-48,
Organism=Escherichia coli, GI1788184, Length=577, Percent_Identity=78.3362218370884, Blast_Score=952, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71985061, Length=595, Percent_Identity=35.7983193277311, Blast_Score=356, Evalue=2e-98,
Organism=Caenorhabditis elegans, GI71985068, Length=563, Percent_Identity=36.234458259325, Blast_Score=347, Evalue=1e-95,
Organism=Caenorhabditis elegans, GI17532153, Length=379, Percent_Identity=27.1767810026385, Blast_Score=149, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6320548, Length=546, Percent_Identity=31.3186813186813, Blast_Score=234, Evalue=2e-62,
Organism=Saccharomyces cerevisiae, GI6321883, Length=557, Percent_Identity=28.9048473967684, Blast_Score=207, Evalue=3e-54,
Organism=Drosophila melanogaster, GI18859963, Length=569, Percent_Identity=35.8523725834798, Blast_Score=368, Evalue=1e-102,
Organism=Drosophila melanogaster, GI28571570, Length=487, Percent_Identity=28.7474332648871, Blast_Score=171, Evalue=1e-42,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_SODGM (Q2NTK2)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_454928.1
- ProteinModelPortal:   Q2NTK2
- SMR:   Q2NTK2
- STRING:   Q2NTK2
- GeneID:   3866771
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG1248
- NMPDR:   fig|343509.6.peg.2591
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   HMGFGTM
- PhylomeDB:   Q2NTK2
- ProtClustDB:   PRK01611
- BioCyc:   SGLO343509:SG1248-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 63718; Mature: 63718

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHTLLSEKIQQALVAAGAPADCEAQVRQSAKAQFGDYQANGVMAIAKQLGLPPRKLAE
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHH
NVVGLLNLDGIARKVDIAGPGFINIFLEPSWLANHLAAALSSPRLGIASVASQTIVVDYS
HHHHHHCCCCCCEEEEECCCCEEEEEECCHHHHHHHHHHHCCCCCCHHHHCCCEEEEEEC
APNVAKEMHVGHVRSTIIGDASVRTLSFLGHNVIRANHVGDWGTQFGMLIAYLEKVQDGG
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHCCCC
EAEMQLSSLESFYRAAKQHYDEDPAFAERARGYVVKLQGGDEYCRQMWRKLVDVTMAQNQ
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHCCC
KTYNRLNVTLTRADVMGESLYNDMLPGIVADLKAKGLAVESEGATVVFLDEFKNKEGEPM
CCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEECCCCCCCCCE
GVIIQKKDGAYLYTTTDIACAKYRYETLKADRIIYYIDSRQHQHLMLAWTIVRKAGYVPE
EEEEEECCCEEEEEECCHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCC
SVPLEHHMFGMMLGKDGKPFKTRAGGTIKLTELLDEALERARRLVAAKNPSMDAGELARL
CCCHHHHHHHHHCCCCCCCCEECCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
AQVVGIGAVKYADLSKSRTTDYVFDWDNMLSFEGNTAPYMQYAYTRVASIFKRSGQDEQQ
HHHHHCCCEEECCCCCCCCCCEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHH
LTGDIRLEAEQETQLAVRLLQLEEAIATVARDGTPHVLCAYLYDLAVLFSAFYEHCPILN
CCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
AENAALRQSRLQLALLTARTLKKGLDLLGIETVERM
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCC
>Mature Secondary Structure
MNIHTLLSEKIQQALVAAGAPADCEAQVRQSAKAQFGDYQANGVMAIAKQLGLPPRKLAE
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHH
NVVGLLNLDGIARKVDIAGPGFINIFLEPSWLANHLAAALSSPRLGIASVASQTIVVDYS
HHHHHHCCCCCCEEEEECCCCEEEEEECCHHHHHHHHHHHCCCCCCHHHHCCCEEEEEEC
APNVAKEMHVGHVRSTIIGDASVRTLSFLGHNVIRANHVGDWGTQFGMLIAYLEKVQDGG
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHCCCC
EAEMQLSSLESFYRAAKQHYDEDPAFAERARGYVVKLQGGDEYCRQMWRKLVDVTMAQNQ
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHCCC
KTYNRLNVTLTRADVMGESLYNDMLPGIVADLKAKGLAVESEGATVVFLDEFKNKEGEPM
CCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEECCCCCCCCCE
GVIIQKKDGAYLYTTTDIACAKYRYETLKADRIIYYIDSRQHQHLMLAWTIVRKAGYVPE
EEEEEECCCEEEEEECCHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCC
SVPLEHHMFGMMLGKDGKPFKTRAGGTIKLTELLDEALERARRLVAAKNPSMDAGELARL
CCCHHHHHHHHHCCCCCCCCEECCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
AQVVGIGAVKYADLSKSRTTDYVFDWDNMLSFEGNTAPYMQYAYTRVASIFKRSGQDEQQ
HHHHHCCCEEECCCCCCCCCCEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHH
LTGDIRLEAEQETQLAVRLLQLEEAIATVARDGTPHVLCAYLYDLAVLFSAFYEHCPILN
CCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
AENAALRQSRLQLALLTARTLKKGLDLLGIETVERM
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA