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The map label for this gene is trxB [H]

Identifier: 85059084

GI number: 85059084

Start: 1831070

End: 1832038

Strand: Reverse

Name: trxB [H]

Synonym: SG1106

Alternate gene names: 85059084

Gene position: 1832038-1831070 (Counterclockwise)

Preceding gene: 85059101

Following gene: 85059083

Centisome position: 43.92

GC content: 59.34

Gene sequence:

>969_bases
ATGTCTACGGTGAAACACAGTAAATTGCTCATATTGGGTTCGGGGCCAGCGGGCTATACAGCCGCGGTCTATGCCGCGCG
CGCCAATCTGAACCCGGTTTTGATCACCGGTATGGAGCAAGGCGGACAGCTGACGACCACCACCGAGGTGGAAAACTGGC
CGGGCGACACGGAAGGACTGACCGGCCCGCTCCTGATGGAGCGCATGTACGCCCACGCCACAAAATTCAACACGGAAATC
ATTTTCGACCACATTACCCAGGTTAATCTGCAAACCCGCCCTTTCCGCCTCGTCGGAGATAGCGGCGAATATACCTGCGA
TGCGCTTATCATCGCCACCGGCGCCTCGGCGCGCTATCTTGGTCTGCCGTCCGAAGAGGCCTATAAAGGGAAAGGGGTTT
CCGCCTGCGCCACCTGCGATGGCTTCTTTTACCGTAACCAGAAAGTGGCGGTGGTCGGCGGCGGCAACACCGCCGTGGAG
GAAGCCCTGTACCTGGCCAATATCGCCGAGGAAGTGCATTTGATCCACCGCCGCGACACCTTTCGTTCGGAAAAGATCCT
TATCGACCGCCTGATGGATAAGGTCAATAACGGCAATATCGTGCTACATACCAATCGTACCCTGGAAGAAGTGCTGGGCG
ACGAGATGGGCGTCACCGGCGTACGTCTGAAAGAGGTGGCCGGCAGCGCCCATGAAGATCTGGCGGTCGCCGGGGTATTT
ATCGCTATAGGTCACAGTCCAAATACCGCGATTTTCGGCGACCAATTGGCGCTGCAAAACGGCTATCTGCGCGTGCAGTC
CGGGATCAATGGCAACGCGACCGCTACCTCGATTCCGGGCGTATTCGCGGCCGGCGACGTCATGGACCACAACTACCGCC
AGGCGATTACCTCCGCCGGGACCGGCTGTATGGCGGCGCTGGACGCCGAACGTTATCTCGACGGCCTGGCCCAGGCCGGC
TCCCTTTGA

Upstream 100 bases:

>100_bases
TTAATTGGAAAAATCGTTAACTACTTTTTTTCATCCTTTTTTAACTCTGGTAATTTTCTTACAATGCCCAGGTTAATGAG
GCGACGACAACGAGGAAAAC

Downstream 100 bases:

>100_bases
GATAATACAATCGCTGCGCAGCAGGGCCGGCGCGCACGCCTCGTTGCCGCCAGGATTGGTCAGGGCGGCCAACGGCCGCC
TTTTCTTTGCCCTGCCCCTG

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MSTVKHSKLLILGSGPAGYTAAVYAARANLNPVLITGMEQGGQLTTTTEVENWPGDTEGLTGPLLMERMYAHATKFNTEI
IFDHITQVNLQTRPFRLVGDSGEYTCDALIIATGASARYLGLPSEEAYKGKGVSACATCDGFFYRNQKVAVVGGGNTAVE
EALYLANIAEEVHLIHRRDTFRSEKILIDRLMDKVNNGNIVLHTNRTLEEVLGDEMGVTGVRLKEVAGSAHEDLAVAGVF
IAIGHSPNTAIFGDQLALQNGYLRVQSGINGNATATSIPGVFAAGDVMDHNYRQAITSAGTGCMAALDAERYLDGLAQAG
SL

Sequences:

>Translated_322_residues
MSTVKHSKLLILGSGPAGYTAAVYAARANLNPVLITGMEQGGQLTTTTEVENWPGDTEGLTGPLLMERMYAHATKFNTEI
IFDHITQVNLQTRPFRLVGDSGEYTCDALIIATGASARYLGLPSEEAYKGKGVSACATCDGFFYRNQKVAVVGGGNTAVE
EALYLANIAEEVHLIHRRDTFRSEKILIDRLMDKVNNGNIVLHTNRTLEEVLGDEMGVTGVRLKEVAGSAHEDLAVAGVF
IAIGHSPNTAIFGDQLALQNGYLRVQSGINGNATATSIPGVFAAGDVMDHNYRQAITSAGTGCMAALDAERYLDGLAQAG
SL
>Mature_321_residues
STVKHSKLLILGSGPAGYTAAVYAARANLNPVLITGMEQGGQLTTTTEVENWPGDTEGLTGPLLMERMYAHATKFNTEII
FDHITQVNLQTRPFRLVGDSGEYTCDALIIATGASARYLGLPSEEAYKGKGVSACATCDGFFYRNQKVAVVGGGNTAVEE
ALYLANIAEEVHLIHRRDTFRSEKILIDRLMDKVNNGNIVLHTNRTLEEVLGDEMGVTGVRLKEVAGSAHEDLAVAGVFI
AIGHSPNTAIFGDQLALQNGYLRVQSGINGNATATSIPGVFAAGDVMDHNYRQAITSAGTGCMAALDAERYLDGLAQAGS
L

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=320, Percent_Identity=84.375, Blast_Score=557, Evalue=1e-160,
Organism=Escherichia coli, GI87081763, Length=316, Percent_Identity=33.5443037974684, Blast_Score=128, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6320560, Length=323, Percent_Identity=46.749226006192, Blast_Score=280, Evalue=2e-76,
Organism=Saccharomyces cerevisiae, GI6321898, Length=325, Percent_Identity=46.4615384615385, Blast_Score=280, Evalue=3e-76,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34251; Mature: 34120

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVKHSKLLILGSGPAGYTAAVYAARANLNPVLITGMEQGGQLTTTTEVENWPGDTEGL
CCCCCCCEEEEEECCCCCCEEEEEEEECCCCEEEEEECCCCCEEEEEEECCCCCCCCCCC
TGPLLMERMYAHATKFNTEIIFDHITQVNLQTRPFRLVGDSGEYTCDALIIATGASARYL
CHHHHHHHHHHHHHHCCCEEEEEHHEEEECCCCCEEEECCCCCEEEEEEEEEECCCEEEE
GLPSEEAYKGKGVSACATCDGFFYRNQKVAVVGGGNTAVEEALYLANIAEEVHLIHRRDT
CCCCCHHHCCCCCEEEEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCC
FRSEKILIDRLMDKVNNGNIVLHTNRTLEEVLGDEMGVTGVRLKEVAGSAHEDLAVAGVF
CCHHHHHHHHHHHHCCCCCEEEECCCHHHHHCCCCCCCCCEEHHHHCCCCCCCCEEEEEE
IAIGHSPNTAIFGDQLALQNGYLRVQSGINGNATATSIPGVFAAGDVMDHNYRQAITSAG
EEECCCCCCEEECCCEEECCCEEEEECCCCCCCCEECCCCCEEECCHHCCHHHHHHHHCC
TGCMAALDAERYLDGLAQAGSL
CCCEEHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
STVKHSKLLILGSGPAGYTAAVYAARANLNPVLITGMEQGGQLTTTTEVENWPGDTEGL
CCCCCCEEEEEECCCCCCEEEEEEEECCCCEEEEEECCCCCEEEEEEECCCCCCCCCCC
TGPLLMERMYAHATKFNTEIIFDHITQVNLQTRPFRLVGDSGEYTCDALIIATGASARYL
CHHHHHHHHHHHHHHCCCEEEEEHHEEEECCCCCEEEECCCCCEEEEEEEEEECCCEEEE
GLPSEEAYKGKGVSACATCDGFFYRNQKVAVVGGGNTAVEEALYLANIAEEVHLIHRRDT
CCCCCHHHCCCCCEEEEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCC
FRSEKILIDRLMDKVNNGNIVLHTNRTLEEVLGDEMGVTGVRLKEVAGSAHEDLAVAGVF
CCHHHHHHHHHHHHCCCCCEEEECCCHHHHHCCCCCCCCCEEHHHHCCCCCCCCEEEEEE
IAIGHSPNTAIFGDQLALQNGYLRVQSGINGNATATSIPGVFAAGDVMDHNYRQAITSAG
EEECCCCCCEEECCCEEECCCEEEEECCCCCCCCEECCCCCEEECCHHCCHHHHHHHHCC
TGCMAALDAERYLDGLAQAGSL
CCCEEHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]