Click here to switch to the map view.

The map label for this gene is moeA [H]

Identifier: 85058898

GI number: 85058898

Start: 1502867

End: 1503928

Strand: Reverse

Name: moeA [H]

Synonym: SG0920

Alternate gene names: 85058898

Gene position: 1503928-1502867 (Counterclockwise)

Preceding gene: 85058900

Following gene: 85058895

Centisome position: 36.06

GC content: 63.09

Gene sequence:

>1062_bases
TTGCTTACAGGAGTTGCCATGGCTTCCACTCCTTCCCCGTTGCTGACGCTTGAGCAGGCGTTGGCCACTATACTCGACAC
CGTCGACACGGTCACGGCGACCGATATCGAGAACGTGCCCTTGACCAACGCCTGCGGTCGCATCAGAGCCGAACCTATTG
TTTCGCCGGTCAATGTGCCGCCGTTTGACAATGCCGCCATGGACGGTTATGCCGTCAGACGGGCAGACCTCGCGCCGGGC
GCGGCGTTGCCTGTGGCGGGACGGGCGCTGGCGGGGGTGCCGTTCACCGGCCCCTGGCCTGCGGGCAGTGCGCTTCGCAT
CATGACCGGCGCGCCGACCCCGGCCGGCGCCGAGGCGGTCATCATGCAAGAATACGCGGAGGTCAGCGAACAGGGTGTGC
GGTTTAGCGTTTCACCCGCCGCCGGCGAAAATATCCGTCGGGTCGGCGATGATATTCGTCAAGGAGACGAGGTGCTGCCG
GCGGGCCGGCTATTACAGGTGGAGGAGCTGCCGCTGCTGGCATCCCTGGGCATCGCCTCGGTACGCGTCTGCCGCCGTCT
GCGCGTGGCCTTGTTTTCCACCGGCTATGAACTGCGGCCGATCGGCGCACCGCTGGCCGCCGGCGAGATCTACGACACCA
ACCGCTTCGCCATCAGGCTGATGCTCACCCGGTTAAGCTGCGAGGTCATAGATTTAGGGATTATCGCCGACGATGCCGCC
GCCTTACATGAAGCGTTTCGTCAGGCGGACAGCCGGGCGGATTTACTCATCACCAGCGGCGGCGTGTCGGTCGGTGAGGC
GGACTATACCAAAACTATGCTGGAAGAATTGGGGCATATTCATTTCTGGAAACTGGCGATGAAGCCCGGCAAACCCTTCG
CCTTCGGCCGGCTGGATTTTCAACGCGGCTGCTACCGCATAGACACCGCGGGCGATGTGGCAGTCGCCAGTACCGGTCCG
CAGGGATCCCATGTGTTCAGCTCCTTCGCCAACGTCAACTGCTTTATCGTGCTGGAGCAAGCGCGCGGCGACGTGGCCGC
CGGCGAATGTGTGACCATATAA

Upstream 100 bases:

>100_bases
CGCGCGCGTCCACGCATGCACGCCGGCCCGGTTCTCTGGTATCGGGTTCTCTGCCATAATAAGGGCTGCTTAGCATCAGG
CGGTTTTCACCGGATCCCCG

Downstream 100 bases:

>100_bases
CCGTTCAATAGCCTGCTGCAAGGCTGAGGAGTCTGGATGGCGGCGGAATTAACTCATCGGGAGATGCTGCGCTACAACCG
CCAGATTATGTTGCGCGGCT

Product: putative molybdopterin biosynthesis protein MoeA

Products: NA

Alternate protein names: MPT Mo-transferase [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MLTGVAMASTPSPLLTLEQALATILDTVDTVTATDIENVPLTNACGRIRAEPIVSPVNVPPFDNAAMDGYAVRRADLAPG
AALPVAGRALAGVPFTGPWPAGSALRIMTGAPTPAGAEAVIMQEYAEVSEQGVRFSVSPAAGENIRRVGDDIRQGDEVLP
AGRLLQVEELPLLASLGIASVRVCRRLRVALFSTGYELRPIGAPLAAGEIYDTNRFAIRLMLTRLSCEVIDLGIIADDAA
ALHEAFRQADSRADLLITSGGVSVGEADYTKTMLEELGHIHFWKLAMKPGKPFAFGRLDFQRGCYRIDTAGDVAVASTGP
QGSHVFSSFANVNCFIVLEQARGDVAAGECVTI

Sequences:

>Translated_353_residues
MLTGVAMASTPSPLLTLEQALATILDTVDTVTATDIENVPLTNACGRIRAEPIVSPVNVPPFDNAAMDGYAVRRADLAPG
AALPVAGRALAGVPFTGPWPAGSALRIMTGAPTPAGAEAVIMQEYAEVSEQGVRFSVSPAAGENIRRVGDDIRQGDEVLP
AGRLLQVEELPLLASLGIASVRVCRRLRVALFSTGYELRPIGAPLAAGEIYDTNRFAIRLMLTRLSCEVIDLGIIADDAA
ALHEAFRQADSRADLLITSGGVSVGEADYTKTMLEELGHIHFWKLAMKPGKPFAFGRLDFQRGCYRIDTAGDVAVASTGP
QGSHVFSSFANVNCFIVLEQARGDVAAGECVTI
>Mature_353_residues
MLTGVAMASTPSPLLTLEQALATILDTVDTVTATDIENVPLTNACGRIRAEPIVSPVNVPPFDNAAMDGYAVRRADLAPG
AALPVAGRALAGVPFTGPWPAGSALRIMTGAPTPAGAEAVIMQEYAEVSEQGVRFSVSPAAGENIRRVGDDIRQGDEVLP
AGRLLQVEELPLLASLGIASVRVCRRLRVALFSTGYELRPIGAPLAAGEIYDTNRFAIRLMLTRLSCEVIDLGIIADDAA
ALHEAFRQADSRADLLITSGGVSVGEADYTKTMLEELGHIHFWKLAMKPGKPFAFGRLDFQRGCYRIDTAGDVAVASTGP
QGSHVFSSFANVNCFIVLEQARGDVAAGECVTI

Specific function: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP [H]

COG id: COG0303

COG function: function code H; Molybdopterin biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moeA family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=301, Percent_Identity=37.8737541528239, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI66932975, Length=301, Percent_Identity=37.8737541528239, Blast_Score=169, Evalue=4e-42,
Organism=Escherichia coli, GI1787049, Length=388, Percent_Identity=51.2886597938144, Blast_Score=361, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI25147659, Length=260, Percent_Identity=34.6153846153846, Blast_Score=134, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17562606, Length=222, Percent_Identity=28.3783783783784, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI17136978, Length=295, Percent_Identity=29.8305084745763, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24638841, Length=295, Percent_Identity=29.8305084745763, Blast_Score=119, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR005111
- InterPro:   IPR005110
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth; PF03454 MoeA_C; PF03453 MoeA_N [H]

EC number: NA

Molecular weight: Translated: 37230; Mature: 37230

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS01079 MOCF_BIOSYNTHESIS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTGVAMASTPSPLLTLEQALATILDTVDTVTATDIENVPLTNACGRIRAEPIVSPVNVP
CCCCCEECCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCC
PFDNAAMDGYAVRRADLAPGAALPVAGRALAGVPFTGPWPAGSALRIMTGAPTPAGAEAV
CCCCCCCCCEEEEECCCCCCCCCCCCCCHHCCCCCCCCCCCCCEEEEEECCCCCCCCHHH
IMQEYAEVSEQGVRFSVSPAAGENIRRVGDDIRQGDEVLPAGRLLQVEELPLLASLGIAS
HHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHCCHHH
VRVCRRLRVALFSTGYELRPIGAPLAAGEIYDTNRFAIRLMLTRLSCEVIDLGIIADDAA
HHHHHHHHHHHHHCCCEEEECCCCCCCCEEECCCHHEEEHHHHHHCCEEEEEEEEECCHH
ALHEAFRQADSRADLLITSGGVSVGEADYTKTMLEELGHIHFWKLAMKPGKPFAFGRLDF
HHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCEEEECEEC
QRGCYRIDTAGDVAVASTGPQGSHVFSSFANVNCFIVLEQARGDVAAGECVTI
CCCCEEECCCCCEEEECCCCCCHHHHHHHCCCEEEEEEEECCCCCCCCCEEEC
>Mature Secondary Structure
MLTGVAMASTPSPLLTLEQALATILDTVDTVTATDIENVPLTNACGRIRAEPIVSPVNVP
CCCCCEECCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCC
PFDNAAMDGYAVRRADLAPGAALPVAGRALAGVPFTGPWPAGSALRIMTGAPTPAGAEAV
CCCCCCCCCEEEEECCCCCCCCCCCCCCHHCCCCCCCCCCCCCEEEEEECCCCCCCCHHH
IMQEYAEVSEQGVRFSVSPAAGENIRRVGDDIRQGDEVLPAGRLLQVEELPLLASLGIAS
HHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHCCHHH
VRVCRRLRVALFSTGYELRPIGAPLAAGEIYDTNRFAIRLMLTRLSCEVIDLGIIADDAA
HHHHHHHHHHHHHCCCEEEECCCCCCCCEEECCCHHEEEHHHHHHCCEEEEEEEEECCHH
ALHEAFRQADSRADLLITSGGVSVGEADYTKTMLEELGHIHFWKLAMKPGKPFAFGRLDF
HHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCEEEECEEC
QRGCYRIDTAGDVAVASTGPQGSHVFSSFANVNCFIVLEQARGDVAAGECVTI
CCCCEEECCCCCEEEECCCCCCHHHHHHHCCCEEEEEEEECCCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]