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The map label for this gene is coaE

Identifier: 85058439

GI number: 85058439

Start: 796113

End: 796739

Strand: Reverse

Name: coaE

Synonym: SG0461

Alternate gene names: 85058439

Gene position: 796739-796113 (Counterclockwise)

Preceding gene: 85058440

Following gene: 85058438

Centisome position: 19.1

GC content: 61.72

Gene sequence:

>627_bases
GTGACCCAATACATTGTGGCGTTGACCGGCGGTATCGGCAGCGGTAAAAGCACGGTGGCCAACACCTTTGCCGCACTCGG
CGTGCCCCTGGTGGATGCCGACGTCATCGCCCGGGAAGTGGTGCAGCCGGAAAGTGCGGCTCTGCGCGCCATCGTACAAC
GTTTTGGCCCAGCGATGTTAAGCGCGGACGGCTCGCTGGATCGCGCCGCGCTTCGAGCGCGTATTTTCAGCGACCCGGCA
GAAAAAACCTGGCTTAATGGCCTGCTTCATCCGCTTATTCAACGGCAAACCGAGCAGCAATTGCGCTCCGCCCGCGCGCC
GTACGTGCTGTGGGTGGTGCCGATGCTGATCGAAAACAACCTGCAGCAGCGCGCCAATCGGGTGCTGGTGGTGGATGTGG
ACCGCGAGCGCCAGATCGCGCGCACGATCAGCCGGGACGGCGTCAGCCGCGAGCAGGTGGAAAACATTCTGGCGGCGCAG
GTGTCGCGTCAGCGGCGTCTGGCCTGCGCAGACGATATTATTGATAATAGCGGGCGCCCCGAGGAGATAACGGATCGCGT
TGCTACTTTGCATCAACGCTATCTGGCGCTTGCGGCATCGGCAACCCGACAGGATAAATCATCATGA

Upstream 100 bases:

>100_bases
TTAAAGTTAGGGCAAGACTGCGAAATCTGCCCATTTTACGCTACAATCGTACCAATTTACCTTATGCTAGGAGATTCTCT
TTTAGGGTGAGGCAGTTAAC

Downstream 100 bases:

>100_bases
GTAACGTTTACTCGACAACTGTGCTGTTTGAACACCCGTTAAATGAAAAAATGCGTACCTGGCTGCGGTTGGAGTTTCTA
CTACAGCAGCTTTACCGACA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MTQYIVALTGGIGSGKSTVANTFAALGVPLVDADVIAREVVQPESAALRAIVQRFGPAMLSADGSLDRAALRARIFSDPA
EKTWLNGLLHPLIQRQTEQQLRSARAPYVLWVVPMLIENNLQQRANRVLVVDVDRERQIARTISRDGVSREQVENILAAQ
VSRQRRLACADDIIDNSGRPEEITDRVATLHQRYLALAASATRQDKSS

Sequences:

>Translated_208_residues
MTQYIVALTGGIGSGKSTVANTFAALGVPLVDADVIAREVVQPESAALRAIVQRFGPAMLSADGSLDRAALRARIFSDPA
EKTWLNGLLHPLIQRQTEQQLRSARAPYVLWVVPMLIENNLQQRANRVLVVDVDRERQIARTISRDGVSREQVENILAAQ
VSRQRRLACADDIIDNSGRPEEITDRVATLHQRYLALAASATRQDKSS
>Mature_207_residues
TQYIVALTGGIGSGKSTVANTFAALGVPLVDADVIAREVVQPESAALRAIVQRFGPAMLSADGSLDRAALRARIFSDPAE
KTWLNGLLHPLIQRQTEQQLRSARAPYVLWVVPMLIENNLQQRANRVLVVDVDRERQIARTISRDGVSREQVENILAAQV
SRQRRLACADDIIDNSGRPEEITDRVATLHQRYLALAASATRQDKSS

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain

Homologues:

Organism=Homo sapiens, GI191252797, Length=194, Percent_Identity=36.0824742268041, Blast_Score=117, Evalue=9e-27,
Organism=Homo sapiens, GI191252795, Length=194, Percent_Identity=36.0824742268041, Blast_Score=117, Evalue=9e-27,
Organism=Homo sapiens, GI110227607, Length=186, Percent_Identity=26.3440860215054, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI110227605, Length=186, Percent_Identity=26.3440860215054, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI110227603, Length=186, Percent_Identity=26.3440860215054, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI110227601, Length=186, Percent_Identity=26.3440860215054, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI205277394, Length=186, Percent_Identity=26.3440860215054, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1786292, Length=204, Percent_Identity=61.2745098039216, Blast_Score=249, Evalue=7e-68,
Organism=Caenorhabditis elegans, GI17554944, Length=188, Percent_Identity=32.9787234042553, Blast_Score=116, Evalue=8e-27,
Organism=Saccharomyces cerevisiae, GI6320402, Length=197, Percent_Identity=33.502538071066, Blast_Score=96, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24644728, Length=183, Percent_Identity=33.3333333333333, Blast_Score=111, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24658602, Length=190, Percent_Identity=30, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAE_SODGM (Q2NVT9)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_454141.1
- ProteinModelPortal:   Q2NVT9
- SMR:   Q2NVT9
- STRING:   Q2NVT9
- GeneID:   3868201
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG0461
- NMPDR:   fig|343509.6.peg.1035
- eggNOG:   COG0237
- HOGENOM:   HBG650290
- OMA:   IIAREVV
- PhylomeDB:   Q2NVT9
- ProtClustDB:   PRK00081
- BioCyc:   SGLO343509:SG0461-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00376
- InterPro:   IPR001977
- TIGRFAMs:   TIGR00152

Pfam domain/function: PF01121 CoaE

EC number: =2.7.1.24

Molecular weight: Translated: 22876; Mature: 22745

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS51219 DPCK; PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQYIVALTGGIGSGKSTVANTFAALGVPLVDADVIAREVVQPESAALRAIVQRFGPAML
CCEEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHH
SADGSLDRAALRARIFSDPAEKTWLNGLLHPLIQRQTEQQLRSARAPYVLWVVPMLIENN
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LQQRANRVLVVDVDRERQIARTISRDGVSREQVENILAAQVSRQRRLACADDIIDNSGRP
HHHHCCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EEITDRVATLHQRYLALAASATRQDKSS
HHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TQYIVALTGGIGSGKSTVANTFAALGVPLVDADVIAREVVQPESAALRAIVQRFGPAML
CEEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHH
SADGSLDRAALRARIFSDPAEKTWLNGLLHPLIQRQTEQQLRSARAPYVLWVVPMLIENN
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LQQRANRVLVVDVDRERQIARTISRDGVSREQVENILAAQVSRQRRLACADDIIDNSGRP
HHHHCCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EEITDRVATLHQRYLALAASATRQDKSS
HHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA