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The map label for this gene is apaH

Identifier: 85058400

GI number: 85058400

Start: 744919

End: 745767

Strand: Reverse

Name: apaH

Synonym: SG0422

Alternate gene names: 85058400

Gene position: 745767-744919 (Counterclockwise)

Preceding gene: 85058401

Following gene: 85058390

Centisome position: 17.88

GC content: 59.01

Gene sequence:

>849_bases
ATGTCGACTTATTTAATTGGTGATATTCACGGCTGCTACGATGAGCTGAAAATCATATTGGCGCAGGTCCGGTTCGATCC
AGCGGTGGATACGCTGTGGCTGACCGGCGATCTGGTCGCGCGCGGGACCGGTTCGCTAGAGGTATTGCGTCTGGTGCGCA
GTCTGGGCGACAGCGTACAGTTGGTGCTGGGCAATCACGATCTCCATCTTTTGGCGGTGTATGCCGGCATCAGCCGCAAT
AAGCCGAAAGATCGCATCACGCCGCTGCTGGAAGCGCCGGACGCTGATGAATTAATCAACTGGCTCCGCCGTCAGCCGGT
GCTACAGGTGGATGAAGAGAAAAAATTGGTCATGGCTCACGCCGGCATTACGCCGCAGTGGGACCTCGCCACGGCGCGCC
AGTGCGCCCGTGAGGTGGAAGCGGTACTGAAGAGCGACAGCTATCCGCTGTTCCTCGACGCCATGTACGGCGATATGCCT
AACAACTGGAGCCCTGAGCTAAGCGGTCTGGCGCGCCTGCGGTTCAGTACCAATGTCTTTACCCGCATGCGCTACTGCTT
CCCCAACGGTCAGCTGGAAATGAACTGCAAGGATACTCCGGAAAAAGCGTCGACGCCGCTGCGGCCGTGGTTCGCGCTAC
CGGGGCCAGTGTCTGAGCGCTATAGCATTGTTTTCGGTCATTGGGCCTCGCTGATGGGCCAGGGAACGCCGGCGCACATC
TACGGGCTTGACACCGGCTGCTGTTGGGGCGGCGAATTGACCCTGCTGCGTTGGGAAGACAAGGCGTTTACCCGCGTACC
CTCGAACCGTCAAAACGAAACCAGCGTCGAAAATCCCATCAGCGCCTGA

Upstream 100 bases:

>100_bases
CCATGCAAGGCCATTACGATATGGTCGATGACCAAGGACAGGGATTTCACGTTGCCATCCCCGTCTTCCGCCTGGCGATT
CCTTCTCTTATAAACTAACT

Downstream 100 bases:

>100_bases
GGTCCACGCCCCTTAATCTGGCGGTTTAACGGCCTGACGGTTCGGCGGTGTTCCGAATCCAGCGCGGGGGCGCCCCGGGA
GGGTCTGGCATCAAACGCGT

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MSTYLIGDIHGCYDELKIILAQVRFDPAVDTLWLTGDLVARGTGSLEVLRLVRSLGDSVQLVLGNHDLHLLAVYAGISRN
KPKDRITPLLEAPDADELINWLRRQPVLQVDEEKKLVMAHAGITPQWDLATARQCAREVEAVLKSDSYPLFLDAMYGDMP
NNWSPELSGLARLRFSTNVFTRMRYCFPNGQLEMNCKDTPEKASTPLRPWFALPGPVSERYSIVFGHWASLMGQGTPAHI
YGLDTGCCWGGELTLLRWEDKAFTRVPSNRQNETSVENPISA

Sequences:

>Translated_282_residues
MSTYLIGDIHGCYDELKIILAQVRFDPAVDTLWLTGDLVARGTGSLEVLRLVRSLGDSVQLVLGNHDLHLLAVYAGISRN
KPKDRITPLLEAPDADELINWLRRQPVLQVDEEKKLVMAHAGITPQWDLATARQCAREVEAVLKSDSYPLFLDAMYGDMP
NNWSPELSGLARLRFSTNVFTRMRYCFPNGQLEMNCKDTPEKASTPLRPWFALPGPVSERYSIVFGHWASLMGQGTPAHI
YGLDTGCCWGGELTLLRWEDKAFTRVPSNRQNETSVENPISA
>Mature_281_residues
STYLIGDIHGCYDELKIILAQVRFDPAVDTLWLTGDLVARGTGSLEVLRLVRSLGDSVQLVLGNHDLHLLAVYAGISRNK
PKDRITPLLEAPDADELINWLRRQPVLQVDEEKKLVMAHAGITPQWDLATARQCAREVEAVLKSDSYPLFLDAMYGDMPN
NWSPELSGLARLRFSTNVFTRMRYCFPNGQLEMNCKDTPEKASTPLRPWFALPGPVSERYSIVFGHWASLMGQGTPAHIY
GLDTGCCWGGELTLLRWEDKAFTRVPSNRQNETSVENPISA

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family

Homologues:

Organism=Escherichia coli, GI1786234, Length=273, Percent_Identity=78.021978021978, Blast_Score=461, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): APAH_SODGM (Q2NVX8)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_454102.1
- ProteinModelPortal:   Q2NVX8
- SMR:   Q2NVX8
- STRING:   Q2NVX8
- GeneID:   3867533
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG0422
- NMPDR:   fig|343509.6.peg.986
- eggNOG:   COG0639
- HOGENOM:   HBG724457
- OMA:   LVFGHWA
- PhylomeDB:   Q2NVX8
- ProtClustDB:   PRK00166
- BioCyc:   SGLO343509:SG0422-MONOMER
- HAMAP:   MF_00199
- InterPro:   IPR004617
- InterPro:   IPR004843
- InterPro:   IPR006186
- PANTHER:   PTHR11668
- PIRSF:   PIRSF000903
- TIGRFAMs:   TIGR00668

Pfam domain/function: PF00149 Metallophos

EC number: =3.6.1.41

Molecular weight: Translated: 31600; Mature: 31469

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTYLIGDIHGCYDELKIILAQVRFDPAVDTLWLTGDLVARGTGSLEVLRLVRSLGDSVQ
CCCEEEECHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEECCCCHHHHHHHHHHCCCCEE
LVLGNHDLHLLAVYAGISRNKPKDRITPLLEAPDADELINWLRRQPVLQVDEEKKLVMAH
EEECCCCEEEEEEEECCCCCCCHHHCCHHHCCCCHHHHHHHHHHCCCEEECCCCEEEEEE
AGITPQWDLATARQCAREVEAVLKSDSYPLFLDAMYGDMPNNWSPELSGLARLRFSTNVF
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
TRMRYCFPNGQLEMNCKDTPEKASTPLRPWFALPGPVSERYSIVFGHWASLMGQGTPAHI
HHHHEECCCCEEEECCCCCCHHCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCCCEEE
YGLDTGCCWGGELTLLRWEDKAFTRVPSNRQNETSVENPISA
EECCCCCEECCCEEEEEECCCHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
STYLIGDIHGCYDELKIILAQVRFDPAVDTLWLTGDLVARGTGSLEVLRLVRSLGDSVQ
CCEEEECHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEECCCCHHHHHHHHHHCCCCEE
LVLGNHDLHLLAVYAGISRNKPKDRITPLLEAPDADELINWLRRQPVLQVDEEKKLVMAH
EEECCCCEEEEEEEECCCCCCCHHHCCHHHCCCCHHHHHHHHHHCCCEEECCCCEEEEEE
AGITPQWDLATARQCAREVEAVLKSDSYPLFLDAMYGDMPNNWSPELSGLARLRFSTNVF
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
TRMRYCFPNGQLEMNCKDTPEKASTPLRPWFALPGPVSERYSIVFGHWASLMGQGTPAHI
HHHHEECCCCEEEECCCCCCHHCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCCCEEE
YGLDTGCCWGGELTLLRWEDKAFTRVPSNRQNETSVENPISA
EECCCCCEECCCEEEEEECCCHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA