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The map label for this gene is fbp

Identifier: 85058334

GI number: 85058334

Start: 649025

End: 650026

Strand: Reverse

Name: fbp

Synonym: SG0356

Alternate gene names: 85058334

Gene position: 650026-649025 (Counterclockwise)

Preceding gene: 85058336

Following gene: 85058333

Centisome position: 15.58

GC content: 53.59

Gene sequence:

>1002_bases
ATGAAAACTTTAGGCGAGTTTATTGTTGAGAAACAGCATGATTTTCCGCATGCCACCGGCGAGCTTACCGCGTTACTTTC
AGCGATAAAGCTCGGGGCTAAAATCATTCACCGTGACATCAACAAAGCAGGACTGGTGGATATCCTCGGCACCAGCGGGG
CTGAAAACGTGCAGGGCGAAGTCCAGATGAAGCTGGATCTGTTCGCGAATGAAAAGCTGAAGGCGGCGCTGAAAGCCCGT
GGACAAGTGGCGGGCATTGCTTCCGAAGAAGAAGATGAAATCGTCGTCTTTGAAGGGGTGGAAAACGGCAAATATGTGGT
GCTGATGGATCCGCTGGACGGTTCGTCCAATATCGATGTCAACGTTTCGGTCGGCACCATTTTCTCCATTTACCGGCGCA
TTACCCCGCTGGGTACACCGGTGACTAAAGAAGATTTCCTTCAGCCCGGCAATAAACAGGTGGCCGCAGGCTATGTGGTC
TACGGTTCCTCCACGATGCTGGTGTACACCACCGGCTGCGGCGTACACGCTTTTACCTACGATCCGTCGCTGGGCGTGTT
TTGCCTGTCCCATGAAAGCGTGCGTTTCCCCGCCACCGGGCAGATGTACTCGATCAACGAGGGCAACTATATCAAGTTCC
CCAACGGGGTGAAGAAATACATCAAATACTGCCAGGAGATGGACGAAGCGACCCACCGTCCTTACACCTCGCGCTATATC
GGTTCGCTGGTGTCCGATTTCCATCGCAATCTACTCAAAGGCGGCATTTATCTTTACCCCAGCACCGCAACCCATCCCAA
CGGCAAGCTGCGCCTGGCCTATGAATGCAATCCAATAGCCTTTCTGGCTGAGCAGGCCGGCGGCAAGGCCAGCGACGGTA
AAAACCGTATACTGGACATCCAGCCGCACGAGCTGCACCAGCGTTCCGCGTTCTTCACTGGCACGGAGTCAATGGTTAAC
GATGTAGAGCGCTTTATCCGCGATTATCCGGATAACGTTTAA

Upstream 100 bases:

>100_bases
GTTTAGGCTAAACTGATGGACAAACGCGTAGTGGTAAAAAAATTATACCGCTTTTCATCCGTAGCTTCAGGGTCCTTTTT
AGAGATTCAGGGAATGTGTC

Downstream 100 bases:

>100_bases
ACCGGGGAAGTTTGTCGGCTCGGCAGCGCAGACTGCCGTGCCGTTACCCTATGCGCCCGCGCCACAGGCCGGGCTGACGC
CGGTGTGACCGGCGCAACAA

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MKTLGEFIVEKQHDFPHATGELTALLSAIKLGAKIIHRDINKAGLVDILGTSGAENVQGEVQMKLDLFANEKLKAALKAR
GQVAGIASEEEDEIVVFEGVENGKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRITPLGTPVTKEDFLQPGNKQVAAGYVV
YGSSTMLVYTTGCGVHAFTYDPSLGVFCLSHESVRFPATGQMYSINEGNYIKFPNGVKKYIKYCQEMDEATHRPYTSRYI
GSLVSDFHRNLLKGGIYLYPSTATHPNGKLRLAYECNPIAFLAEQAGGKASDGKNRILDIQPHELHQRSAFFTGTESMVN
DVERFIRDYPDNV

Sequences:

>Translated_333_residues
MKTLGEFIVEKQHDFPHATGELTALLSAIKLGAKIIHRDINKAGLVDILGTSGAENVQGEVQMKLDLFANEKLKAALKAR
GQVAGIASEEEDEIVVFEGVENGKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRITPLGTPVTKEDFLQPGNKQVAAGYVV
YGSSTMLVYTTGCGVHAFTYDPSLGVFCLSHESVRFPATGQMYSINEGNYIKFPNGVKKYIKYCQEMDEATHRPYTSRYI
GSLVSDFHRNLLKGGIYLYPSTATHPNGKLRLAYECNPIAFLAEQAGGKASDGKNRILDIQPHELHQRSAFFTGTESMVN
DVERFIRDYPDNV
>Mature_333_residues
MKTLGEFIVEKQHDFPHATGELTALLSAIKLGAKIIHRDINKAGLVDILGTSGAENVQGEVQMKLDLFANEKLKAALKAR
GQVAGIASEEEDEIVVFEGVENGKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRITPLGTPVTKEDFLQPGNKQVAAGYVV
YGSSTMLVYTTGCGVHAFTYDPSLGVFCLSHESVRFPATGQMYSINEGNYIKFPNGVKKYIKYCQEMDEATHRPYTSRYI
GSLVSDFHRNLLKGGIYLYPSTATHPNGKLRLAYECNPIAFLAEQAGGKASDGKNRILDIQPHELHQRSAFFTGTESMVN
DVERFIRDYPDNV

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family

Homologues:

Organism=Homo sapiens, GI189083692, Length=329, Percent_Identity=42.8571428571429, Blast_Score=261, Evalue=8e-70,
Organism=Homo sapiens, GI16579888, Length=329, Percent_Identity=42.8571428571429, Blast_Score=261, Evalue=8e-70,
Organism=Homo sapiens, GI22907028, Length=326, Percent_Identity=41.1042944785276, Blast_Score=243, Evalue=2e-64,
Organism=Escherichia coli, GI1790679, Length=331, Percent_Identity=87.0090634441088, Blast_Score=602, Evalue=1e-173,
Organism=Caenorhabditis elegans, GI17508131, Length=330, Percent_Identity=46.3636363636364, Blast_Score=299, Evalue=1e-81,
Organism=Saccharomyces cerevisiae, GI6323409, Length=326, Percent_Identity=42.638036809816, Blast_Score=265, Evalue=7e-72,
Organism=Drosophila melanogaster, GI45550998, Length=325, Percent_Identity=46.1538461538462, Blast_Score=285, Evalue=3e-77,
Organism=Drosophila melanogaster, GI19921562, Length=325, Percent_Identity=46.1538461538462, Blast_Score=285, Evalue=3e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): F16PA_SODGM (Q2NW44)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_454036.1
- HSSP:   P0A993
- ProteinModelPortal:   Q2NW44
- SMR:   Q2NW44
- STRING:   Q2NW44
- GeneID:   3867468
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG0356
- NMPDR:   fig|343509.6.peg.872
- eggNOG:   COG0158
- HOGENOM:   HBG731261
- OMA:   HWEAPVQ
- PhylomeDB:   Q2NW44
- ProtClustDB:   PRK09293
- BioCyc:   SGLO343509:SG0356-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01855
- InterPro:   IPR000146
- PANTHER:   PTHR11556
- PRINTS:   PR00115

Pfam domain/function: PF00316 FBPase

EC number: =3.1.3.11

Molecular weight: Translated: 36671; Mature: 36671

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00124 FBPASE

Important sites: BINDING 206-206 BINDING 239-239 BINDING 269-269

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLGEFIVEKQHDFPHATGELTALLSAIKLGAKIIHRDINKAGLVDILGTSGAENVQGE
CCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCE
VQMKLDLFANEKLKAALKARGQVAGIASEEEDEIVVFEGVENGKYVVLMDPLDGSSNIDV
EEEEEEECCCHHHHHHHHHCCCEEECCCCCCCCEEEEECCCCCCEEEEECCCCCCCCEEE
NVSVGTIFSIYRRITPLGTPVTKEDFLQPGNKQVAAGYVVYGSSTMLVYTTGCGVHAFTY
EEEHHHHHHHHHHHCCCCCCCCHHHHHCCCCCEEEEEEEEECCCEEEEEEECCCEEEEEE
DPSLGVFCLSHESVRFPATGQMYSINEGNYIKFPNGVKKYIKYCQEMDEATHRPYTSRYI
CCCCCEEEECCCCEECCCCCCEEEECCCCEEECCHHHHHHHHHHHHHHHHHCCCHHHHHH
GSLVSDFHRNLLKGGIYLYPSTATHPNGKLRLAYECNPIAFLAEQAGGKASDGKNRILDI
HHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEECCCCEEEHHHCCCCCCCCCCCEEEC
QPHELHQRSAFFTGTESMVNDVERFIRDYPDNV
CCHHHHHHHHEECCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKTLGEFIVEKQHDFPHATGELTALLSAIKLGAKIIHRDINKAGLVDILGTSGAENVQGE
CCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCE
VQMKLDLFANEKLKAALKARGQVAGIASEEEDEIVVFEGVENGKYVVLMDPLDGSSNIDV
EEEEEEECCCHHHHHHHHHCCCEEECCCCCCCCEEEEECCCCCCEEEEECCCCCCCCEEE
NVSVGTIFSIYRRITPLGTPVTKEDFLQPGNKQVAAGYVVYGSSTMLVYTTGCGVHAFTY
EEEHHHHHHHHHHHCCCCCCCCHHHHHCCCCCEEEEEEEEECCCEEEEEEECCCEEEEEE
DPSLGVFCLSHESVRFPATGQMYSINEGNYIKFPNGVKKYIKYCQEMDEATHRPYTSRYI
CCCCCEEEECCCCEECCCCCCEEEECCCCEEECCHHHHHHHHHHHHHHHHHCCCHHHHHH
GSLVSDFHRNLLKGGIYLYPSTATHPNGKLRLAYECNPIAFLAEQAGGKASDGKNRILDI
HHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEECCCCEEEHHHCCCCCCCCCCCEEEC
QPHELHQRSAFFTGTESMVNDVERFIRDYPDNV
CCHHHHHHHHEECCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA