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The map label for this gene is exuR [H]

Identifier: 85058211

GI number: 85058211

Start: 421332

End: 421832

Strand: Reverse

Name: exuR [H]

Synonym: SG0233

Alternate gene names: 85058211

Gene position: 421832-421332 (Counterclockwise)

Preceding gene: 85058213

Following gene: 85058208

Centisome position: 10.11

GC content: 55.49

Gene sequence:

>501_bases
ATGGAACCCACTGAAACCCGCAGATTATACCAGCAGCTGGCGGCCGAACTGAAACGGCGCATCGAATCCGGTAGTTATCC
GGTCGGCGAGAAGCTGCCGGCGGAACGCTATATCGCCGAGGAGATGAATGTCAGCCGCACGGTGGTGCGGGAAGCGATTA
TAATGCTTGAAGTGGAAGGCTATGTGGAAGTCCGCAAAGGCTCGGGTATCCATGTCATCGCCAATCAGCAAAAGCACTTG
TTGTTGCCCGCCGGCGAAATTCAGGCCGCTACGCCTGGTCCGTTTGAGATGCTGCAGGCGCGGCAGCTCATCGAAAGCAA
TATCGCCGAGTTTGCCGCGACCCAAGTGTCAAAACAGGATATTGTCCTGCTAATGGAAATTCAGGAGAACGCCCGTCATG
AGGACAGATTTCGCGATTCGCAGTGGGACTTGAAATTTCACGTTCAGGTGGCGCTGGCCACCGGCAACAGCGCGATGGCG
TCCATAGTGGAACAGATGTAG

Upstream 100 bases:

>100_bases
TGATACAGCGCGCGCAAACATTCCAGCCCGGCCCCCTTTCGTCCCGCCAGCCGCTGAACGTGAGCGCCACCCTTTCTGTG
TATTGTAAAGAGCATCCAAA

Downstream 100 bases:

>100_bases
TCCCAGCGGGTGCATAATCCCTACTGGATCAAGCTGCATGAACATATCGACGACAAAGCGATTGAAAGCTGGTGCAAAGA
TCATGACCAAATTCTTAAGG

Product: putative exu regulon transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MEPTETRRLYQQLAAELKRRIESGSYPVGEKLPAERYIAEEMNVSRTVVREAIIMLEVEGYVEVRKGSGIHVIANQQKHL
LLPAGEIQAATPGPFEMLQARQLIESNIAEFAATQVSKQDIVLLMEIQENARHEDRFRDSQWDLKFHVQVALATGNSAMA
SIVEQM

Sequences:

>Translated_166_residues
MEPTETRRLYQQLAAELKRRIESGSYPVGEKLPAERYIAEEMNVSRTVVREAIIMLEVEGYVEVRKGSGIHVIANQQKHL
LLPAGEIQAATPGPFEMLQARQLIESNIAEFAATQVSKQDIVLLMEIQENARHEDRFRDSQWDLKFHVQVALATGNSAMA
SIVEQM
>Mature_166_residues
MEPTETRRLYQQLAAELKRRIESGSYPVGEKLPAERYIAEEMNVSRTVVREAIIMLEVEGYVEVRKGSGIHVIANQQKHL
LLPAGEIQAATPGPFEMLQARQLIESNIAEFAATQVSKQDIVLLMEIQENARHEDRFRDSQWDLKFHVQVALATGNSAMA
SIVEQM

Specific function: Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the exuT, uxaCA and uxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082208, Length=166, Percent_Identity=74.0963855421687, Blast_Score=246, Evalue=4e-67,
Organism=Escherichia coli, GI1790780, Length=167, Percent_Identity=44.9101796407186, Blast_Score=127, Evalue=4e-31,
Organism=Escherichia coli, GI1790032, Length=155, Percent_Identity=31.6129032258064, Blast_Score=68, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 18775; Mature: 18775

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPTETRRLYQQLAAELKRRIESGSYPVGEKLPAERYIAEEMNVSRTVVREAIIMLEVEG
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHEEECC
YVEVRKGSGIHVIANQQKHLLLPAGEIQAATPGPFEMLQARQLIESNIAEFAATQVSKQD
EEEEECCCCEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
IVLLMEIQENARHEDRFRDSQWDLKFHVQVALATGNSAMASIVEQM
EEEEEEECCCCCHHHHCCCCCCCEEEEEEEEEEECCHHHHHHHHHC
>Mature Secondary Structure
MEPTETRRLYQQLAAELKRRIESGSYPVGEKLPAERYIAEEMNVSRTVVREAIIMLEVEG
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHEEECC
YVEVRKGSGIHVIANQQKHLLLPAGEIQAATPGPFEMLQARQLIESNIAEFAATQVSKQD
EEEEECCCCEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
IVLLMEIQENARHEDRFRDSQWDLKFHVQVALATGNSAMASIVEQM
EEEEEEECCCCCHHHHCCCCCCCEEEEEEEEEEECCHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA