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The map label for this gene is fucR [H]

Identifier: 85058156

GI number: 85058156

Start: 339582

End: 340286

Strand: Reverse

Name: fucR [H]

Synonym: SG0178

Alternate gene names: 85058156

Gene position: 340286-339582 (Counterclockwise)

Preceding gene: 85058157

Following gene: 85058151

Centisome position: 8.16

GC content: 52.34

Gene sequence:

>705_bases
GTGAAAACAACGCGTCAACAGGATCTGGTGCAATTGCTACATCAGCACGGCAGCCTCACCACAGAACAGCTGGCCACCAT
GCTGAATGTGAGTCGCGAGACTATCCGTCGCGATTTGAACGCCCTGCAAAGCCAGGGCAAAGTGTTGCGTCAGCATGGTC
GGGCACGCTGCGTGATAGGCGACAGTGAGGATAACGGCGATCCTTTTCTTACCCGGCTGAAAATCCAGCTCAATAGCAAG
GCTGAGGTCGCCCGGCTGGCGTTGCGCTGGATCGATCCCGGCATGTGTATCGCACTGGATGCCAGCTCGACCTGCTGGTA
TCTGACTAAGCAGTTGCCCGACATGGATATTACGGTATTTACCAATAGCGTGCGTGTCTGTCAGGCATTAATCAAACGCC
AGCATATCCGGCTTATCTGCTCCGGCGGTACCCTGCAGCGCAAATATGCCTGTTATGTGAATGCGGCCATTTTGTCGCAG
CTGAAAAATTTGGAGGTCGATTTGTTCATATTCTCCTGCGAAGGGATCGACCAGGCGGGTGTGATGTGGGATTCCAATTT
GTACAATGCGGGGTTCAAATCTCTGCTGCTTAAACGAGCCGCGCAATCGCTATTGCTGATCGATAAAAGTAAAATGCACC
GCACCGGCGAAATTCGCCTTGGCGACATTAGTCAGGTGACGGAAATCATTACCAACAAAGAGTAG

Upstream 100 bases:

>100_bases
AAGCCGTCCGCTACGGCAATATTTTGCTGAAAAAAGGCATTACGTTTTGATTTTCGGGTGATTATCCGGCCCTGTGCGGC
CAGCGCGAAGGATGTGTGCG

Downstream 100 bases:

>100_bases
CGCTATACCTTGCCGCTAGCAGCCGGCTAACGAGGTGTATTACCTGCGAGTTATCGCTCTTCACCTCACCGGCATCTGCT
TAAGGAACACGGATTTTACC

Product: DNA-binding transcriptional activator FucR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MKTTRQQDLVQLLHQHGSLTTEQLATMLNVSRETIRRDLNALQSQGKVLRQHGRARCVIGDSEDNGDPFLTRLKIQLNSK
AEVARLALRWIDPGMCIALDASSTCWYLTKQLPDMDITVFTNSVRVCQALIKRQHIRLICSGGTLQRKYACYVNAAILSQ
LKNLEVDLFIFSCEGIDQAGVMWDSNLYNAGFKSLLLKRAAQSLLLIDKSKMHRTGEIRLGDISQVTEIITNKE

Sequences:

>Translated_234_residues
MKTTRQQDLVQLLHQHGSLTTEQLATMLNVSRETIRRDLNALQSQGKVLRQHGRARCVIGDSEDNGDPFLTRLKIQLNSK
AEVARLALRWIDPGMCIALDASSTCWYLTKQLPDMDITVFTNSVRVCQALIKRQHIRLICSGGTLQRKYACYVNAAILSQ
LKNLEVDLFIFSCEGIDQAGVMWDSNLYNAGFKSLLLKRAAQSLLLIDKSKMHRTGEIRLGDISQVTEIITNKE
>Mature_234_residues
MKTTRQQDLVQLLHQHGSLTTEQLATMLNVSRETIRRDLNALQSQGKVLRQHGRARCVIGDSEDNGDPFLTRLKIQLNSK
AEVARLALRWIDPGMCIALDASSTCWYLTKQLPDMDITVFTNSVRVCQALIKRQHIRLICSGGTLQRKYACYVNAAILSQ
LKNLEVDLFIFSCEGIDQAGVMWDSNLYNAGFKSLLLKRAAQSLLLIDKSKMHRTGEIRLGDISQVTEIITNKE

Specific function: Transcriptional activator of the fuc operon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789170, Length=233, Percent_Identity=63.0901287553648, Blast_Score=311, Evalue=2e-86,
Organism=Escherichia coli, GI1789829, Length=232, Percent_Identity=27.5862068965517, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1788069, Length=230, Percent_Identity=30.8695652173913, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87082344, Length=233, Percent_Identity=25.3218884120172, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1790753, Length=238, Percent_Identity=26.0504201680672, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789519, Length=234, Percent_Identity=26.4957264957265, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1789059, Length=231, Percent_Identity=27.2727272727273, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI226510968, Length=229, Percent_Identity=25.764192139738, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1790635, Length=230, Percent_Identity=22.6086956521739, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1787540, Length=233, Percent_Identity=23.6051502145923, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1787063, Length=237, Percent_Identity=23.2067510548523, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 26389; Mature: 26389

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTTRQQDLVQLLHQHGSLTTEQLATMLNVSRETIRRDLNALQSQGKVLRQHGRARCVIG
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
DSEDNGDPFLTRLKIQLNSKAEVARLALRWIDPGMCIALDASSTCWYLTKQLPDMDITVF
CCCCCCCCEEEEEEEEECCHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCCCEEEEE
TNSVRVCQALIKRQHIRLICSGGTLQRKYACYVNAAILSQLKNLEVDLFIFSCEGIDQAG
ECHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCC
VMWDSNLYNAGFKSLLLKRAAQSLLLIDKSKMHRTGEIRLGDISQVTEIITNKE
EEECCCHHHHHHHHHHHHHHHHHHEEECHHHCCCCCCEEECCHHHHHHHHCCCC
>Mature Secondary Structure
MKTTRQQDLVQLLHQHGSLTTEQLATMLNVSRETIRRDLNALQSQGKVLRQHGRARCVIG
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
DSEDNGDPFLTRLKIQLNSKAEVARLALRWIDPGMCIALDASSTCWYLTKQLPDMDITVF
CCCCCCCCEEEEEEEEECCHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCCCEEEEE
TNSVRVCQALIKRQHIRLICSGGTLQRKYACYVNAAILSQLKNLEVDLFIFSCEGIDQAG
ECHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCC
VMWDSNLYNAGFKSLLLKRAAQSLLLIDKSKMHRTGEIRLGDISQVTEIITNKE
EEECCCHHHHHHHHHHHHHHHHHHEEECHHHCCCCCCEEECCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2664711; 9278503 [H]