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The map label for this gene is yhdG [H]

Identifier: 84625965

GI number: 84625965

Start: 4868815

End: 4870230

Strand: Reverse

Name: yhdG [H]

Synonym: XOO_4308

Alternate gene names: 84625965

Gene position: 4870230-4868815 (Counterclockwise)

Preceding gene: 84625970

Following gene: 84625964

Centisome position: 98.58

GC content: 65.89

Gene sequence:

>1416_bases
ATGTCGTCTTGGCTCAGGCGCAAATCCATCGATCAGGTCACCGTGCACGAGGCCGGGCGGCAACTGTTGCGCAGCCTGAG
TTGGCCGCATCTGATCGCACTCGGCATCGGCGCCATCGTCGGCACCGGCATCTACACGCTGATCGGCGTGGGTGCCGACA
AGGCCGGCCCTGCGGTGCTGCTGTCGTTCGTGGCCGCCGGCATCGTCTGCGCCTGCGCGGCGCTGGCGTATGCGGAAATG
GCCACGATGATGCCGGCCGCCGGCAGTGCGTACACCTATAGCTACACCGCGCTCGGCGAGAGCATCGCCTGGGTGGTGGG
CTGGAGCCTGGTGCTGGAATATTCGCTGGTGGTCAGCACGGTGGCGGTGGGCTGGTCCGGTTACTTCGTCGGCTTCCTGC
AGTGGCTGGGGGCGAGCTTGCCGCATGAACTGATCGCCGGGCCGCATGCCGGCGGCATCGCGAACCTGCCGGCGGTGGTG
ATCACCTTCCTGGTGGCCGGCATGCTGATGGCCGGCACCAAGGAAAGCGCCACGCTCAATGCGGTGCTGGTGGTGCTGAA
GATCATCGCGCTGGGCGTGTTCGTGGCCATTGCGTTGCCGACCTTCAAAAGCGCCAACCTGCAGCCGTTCATGCCGTATG
GCATCTCCAAGGCCATGGGTCCCGATGGCGTGGAGCGCGGGGTGATGGCGGCGGCGGCGATCATCTTCTTCGCGTTCTAT
GGCTTCGATGCGATTTCCACCGCGGCCGAAGAAACCAAGAACCCCGGGCGCGATCTGTCGATCGGCATCGTCGGCTCGAT
GATCGGCTGCACGCTGATCTATGTGCTGGTGGCACTGGCCGCGGTGGGTGCGATGCGCTTCACCGTGTTTGGCAAGAGTC
CCGAACCGTTGGCGCTGATCCTGCGCGAACTCGGCCACGGCAAGGCGGCCCTGGTGATCGGTGCCGTGGCGATCATTGCG
TTGCCGACGGTGCTGCTGGCGTTTTTGTACGGGCAAAGCCGCATCTTCTTCGTGATGTCGCGCGATGGCTTGTTGCCGCG
CGGCTTGTCCAAGGTCAATGCACGTACCGGCACGCCGGTGGCGATCACGCTGCTTACTGCGGTGCTGGTGGCGGCATTGG
CGGGCGTGGCCCGGTTGGACGAAATCGCTGCACTGGCCAATGCCGGCACGCTGGCCGCATTCACCGCGGTGGCAGCCTGC
CTGTTGGTGTTGCGCGTGCGCGAGCCCGGCCGCGCGCGCGCGTTCCGCACGCCGCTGGCGTGGGTGGTGGGACCGGTGGC
GATCCTGGGCTGCCTGTACCTGTTCTGGAGTTTGCCGAGCAACACGCAGGGCTGGTTCCTGCTGTGGAATGCGCTGGGCG
TGGTGGTGTACCTGGCGTATGGGCGGCGTAATAGCCGGTTGAATTCGGCTGGCTGA

Upstream 100 bases:

>100_bases
TATCTGGCTGCACGCAGCCAACGCGACGAGTTGGACCGATAGCTTTGCTGTGCTGCGTTGGGCGACACTCGCGCATTGTG
TTGAATCCCGCGAGGTCCGC

Downstream 100 bases:

>100_bases
GAGTTTTTGAGAGGACGCTTTCAGCTGGGTTGGGCGATGCCGACCAGTCCCTTCTCCCACCGGGACATTATCCTCCTGCA
TGGGGGAGCCTGATTAGCAC

Product: amino acid transporter

Products: Proton [Cytoplasm]; 4-aminobutyrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MSSWLRRKSIDQVTVHEAGRQLLRSLSWPHLIALGIGAIVGTGIYTLIGVGADKAGPAVLLSFVAAGIVCACAALAYAEM
ATMMPAAGSAYTYSYTALGESIAWVVGWSLVLEYSLVVSTVAVGWSGYFVGFLQWLGASLPHELIAGPHAGGIANLPAVV
ITFLVAGMLMAGTKESATLNAVLVVLKIIALGVFVAIALPTFKSANLQPFMPYGISKAMGPDGVERGVMAAAAIIFFAFY
GFDAISTAAEETKNPGRDLSIGIVGSMIGCTLIYVLVALAAVGAMRFTVFGKSPEPLALILRELGHGKAALVIGAVAIIA
LPTVLLAFLYGQSRIFFVMSRDGLLPRGLSKVNARTGTPVAITLLTAVLVAALAGVARLDEIAALANAGTLAAFTAVAAC
LLVLRVREPGRARAFRTPLAWVVGPVAILGCLYLFWSLPSNTQGWFLLWNALGVVVYLAYGRRNSRLNSAG

Sequences:

>Translated_471_residues
MSSWLRRKSIDQVTVHEAGRQLLRSLSWPHLIALGIGAIVGTGIYTLIGVGADKAGPAVLLSFVAAGIVCACAALAYAEM
ATMMPAAGSAYTYSYTALGESIAWVVGWSLVLEYSLVVSTVAVGWSGYFVGFLQWLGASLPHELIAGPHAGGIANLPAVV
ITFLVAGMLMAGTKESATLNAVLVVLKIIALGVFVAIALPTFKSANLQPFMPYGISKAMGPDGVERGVMAAAAIIFFAFY
GFDAISTAAEETKNPGRDLSIGIVGSMIGCTLIYVLVALAAVGAMRFTVFGKSPEPLALILRELGHGKAALVIGAVAIIA
LPTVLLAFLYGQSRIFFVMSRDGLLPRGLSKVNARTGTPVAITLLTAVLVAALAGVARLDEIAALANAGTLAAFTAVAAC
LLVLRVREPGRARAFRTPLAWVVGPVAILGCLYLFWSLPSNTQGWFLLWNALGVVVYLAYGRRNSRLNSAG
>Mature_470_residues
SSWLRRKSIDQVTVHEAGRQLLRSLSWPHLIALGIGAIVGTGIYTLIGVGADKAGPAVLLSFVAAGIVCACAALAYAEMA
TMMPAAGSAYTYSYTALGESIAWVVGWSLVLEYSLVVSTVAVGWSGYFVGFLQWLGASLPHELIAGPHAGGIANLPAVVI
TFLVAGMLMAGTKESATLNAVLVVLKIIALGVFVAIALPTFKSANLQPFMPYGISKAMGPDGVERGVMAAAAIIFFAFYG
FDAISTAAEETKNPGRDLSIGIVGSMIGCTLIYVLVALAAVGAMRFTVFGKSPEPLALILRELGHGKAALVIGAVAIIAL
PTVLLAFLYGQSRIFFVMSRDGLLPRGLSKVNARTGTPVAITLLTAVLVAALAGVARLDEIAALANAGTLAAFTAVAACL
LVLRVREPGRARAFRTPLAWVVGPVAILGCLYLFWSLPSNTQGWFLLWNALGVVVYLAYGRRNSRLNSAG

Specific function: Transporter For Gaba. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI258645169, Length=441, Percent_Identity=35.827664399093, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI258614003, Length=441, Percent_Identity=34.4671201814059, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI258614005, Length=441, Percent_Identity=34.4671201814059, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI4507047, Length=437, Percent_Identity=33.6384439359268, Blast_Score=193, Evalue=3e-49,
Organism=Homo sapiens, GI114326544, Length=438, Percent_Identity=32.1917808219178, Blast_Score=175, Evalue=8e-44,
Organism=Homo sapiens, GI114326550, Length=438, Percent_Identity=32.1917808219178, Blast_Score=175, Evalue=8e-44,
Organism=Homo sapiens, GI181337167, Length=406, Percent_Identity=33.0049261083744, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI110347453, Length=416, Percent_Identity=34.1346153846154, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI115648063, Length=407, Percent_Identity=25.7985257985258, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI115648022, Length=407, Percent_Identity=25.7985257985258, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI186910308, Length=408, Percent_Identity=25.7352941176471, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI186910306, Length=408, Percent_Identity=25.7352941176471, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI186910304, Length=408, Percent_Identity=25.7352941176471, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1789017, Length=355, Percent_Identity=24.7887323943662, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1786302, Length=373, Percent_Identity=25.4691689008043, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1786789, Length=435, Percent_Identity=22.5287356321839, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081869, Length=478, Percent_Identity=24.2677824267782, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082023, Length=482, Percent_Identity=24.6887966804979, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1788480, Length=350, Percent_Identity=24.5714285714286, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI87082250, Length=348, Percent_Identity=24.4252873563218, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081915, Length=444, Percent_Identity=24.3243243243243, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1786602, Length=415, Percent_Identity=22.1686746987952, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI87081708, Length=425, Percent_Identity=23.0588235294118, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1786694, Length=448, Percent_Identity=24.7767857142857, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=406, Percent_Identity=33.743842364532, Blast_Score=183, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17533459, Length=417, Percent_Identity=30.9352517985612, Blast_Score=162, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17531343, Length=417, Percent_Identity=27.8177458033573, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17540018, Length=441, Percent_Identity=24.7165532879819, Blast_Score=95, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI32566699, Length=376, Percent_Identity=24.2021276595745, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71990446, Length=418, Percent_Identity=22.488038277512, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6321053, Length=383, Percent_Identity=23.2375979112272, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24668806, Length=429, Percent_Identity=35.6643356643357, Blast_Score=209, Evalue=4e-54,
Organism=Drosophila melanogaster, GI21356285, Length=429, Percent_Identity=35.6643356643357, Blast_Score=209, Evalue=4e-54,
Organism=Drosophila melanogaster, GI24668802, Length=429, Percent_Identity=35.6643356643357, Blast_Score=209, Evalue=4e-54,
Organism=Drosophila melanogaster, GI24667468, Length=425, Percent_Identity=34.8235294117647, Blast_Score=196, Evalue=4e-50,
Organism=Drosophila melanogaster, GI24666159, Length=432, Percent_Identity=33.7962962962963, Blast_Score=194, Evalue=2e-49,
Organism=Drosophila melanogaster, GI221512776, Length=432, Percent_Identity=33.7962962962963, Blast_Score=194, Evalue=2e-49,
Organism=Drosophila melanogaster, GI161077963, Length=431, Percent_Identity=31.7865429234339, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI281366235, Length=423, Percent_Identity=31.2056737588652, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI116007820, Length=423, Percent_Identity=31.2056737588652, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI116007818, Length=427, Percent_Identity=30.6791569086651, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI85725152, Length=427, Percent_Identity=30.6791569086651, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI45550968, Length=420, Percent_Identity=25.4761904761905, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI19921172, Length=420, Percent_Identity=25.4761904761905, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221331183, Length=436, Percent_Identity=23.8532110091743, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI17647653, Length=436, Percent_Identity=23.8532110091743, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24664379, Length=436, Percent_Identity=23.8532110091743, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004758
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49127; Mature: 48996

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SSWLRRKSIDQVTVHEAGRQLLRSLSWPHLIALGIGAIVGTGIYTLIGVGADKAGPAVL
CCHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH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HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 4-aminobutyrate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 4-aminobutyrate [Periplasm] = Proton [Cytoplasm] + 4-aminobutyrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]