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The map label for this gene is degA [H]

Identifier: 84625818

GI number: 84625818

Start: 4699757

End: 4700824

Strand: Reverse

Name: degA [H]

Synonym: XOO_4161

Alternate gene names: 84625818

Gene position: 4700824-4699757 (Counterclockwise)

Preceding gene: 84625825

Following gene: 84625816

Centisome position: 95.15

GC content: 64.89

Gene sequence:

>1068_bases
TTGGACAAGGTCAGGAAATCGGTCCGCCGCACCAGCCGCGCGACCACCATCGACGAGGTGGCGGCGCTGGCGAAGGTGTC
GCCGATGACGGTTTCGCGCGTGGTCAACAACACCGGCGGAGTGCGCGATGCCACCCGCGAACGGGTCATGCGCGCGGTCG
ACAAGCTGGGCTACACGCCCAATCTTGCTGCCAGTGCATTGGCGGCCGCGCAGAGCACGCGCATTGCGTTGATCTACAGC
GATCCCAGCGGCGCCTACTTGCGCGAGTTGTTGCTGGGCGTGTTGCGGGTCGCCTCGCGTACCCCGATCCAGCTGGTGAT
CGACTGCTGGGACGACCTGGATGCCGATGCCGAACGCAAGGCCGCACGCAAGCTCGCCAAAGGCGTTGCCGGCGTGATCC
TGCCGCCACCCTTGTGCGAATCCAAAGCTGCCGTGCTGGAGTTGGTCCGCGCCAAGGTGCCGGTGGTGGCGATCGCCTCC
AACTATTTCAGCCCGGATGTCGCGTGTGTGCGCATCGACGAATTCACTGCCGCCAAAGAGATCACCGAACACTTGATCGC
GCAGGGGCATACGCGCATCGGCTACATCGCCGGGCATCCGAACCTGTCCGCCAGTACGCGGCGCTTCGAAGGCTTTCAGG
CGGCATTGGAAGACGCCGGCTTGCGCCTGGATCTGCATCTGGTGCAGCCGGGCGATTACACCTACAAATCCGGCCTGGTG
GCCGCGGAAAAATTGCTGGCGCGCAAATGCCGCCCCAGCGCCATCTTCGCCAGTAACGACGACATGGCCGCCGCGGCAAT
CTCGGTCGCGCATCGGCGTGGGCTGGATGTGCCGCGCGATCTGTCGGTGGTCGGTTTCGACGACACGTCGGCCGCCACTG
CGGTGTGGCCCGAAATCACCACCGTGCAGCAACCCATCGCCGCCATGGCCGATGCCGCGCTGGACATCTTGCTGAAGACG
ATTCGCGCCAAGGAGCGTACGGCGAAGATGGTCGATCATGTGGTCGCGCACCTGCTGGTCAAGCGAGATTCGGTGGCCGC
ACCGACAGCGGACGATGCGGTCGAGTAA

Upstream 100 bases:

>100_bases
GTACCATGGCCCACACCGTCATACCTGCATTCGGCACCCGCGTTACCGCAGCAGTGCCTGTGCATCCCGCAGCTTTCGCA
CGCATTTGAAGAGGCCACGT

Downstream 100 bases:

>100_bases
ACATGGCGATCAGACGGCTGCATCGCTGTACGGCGGACGTGGTCATGTCACAGAGCTGCATGTAGCGCGTGGGGATTGCG
GATGTGCGTTCACTCACCTG

Product: sal operon transcriptional repressor

Products: NA

Alternate protein names: Degradation activator [H]

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MDKVRKSVRRTSRATTIDEVAALAKVSPMTVSRVVNNTGGVRDATRERVMRAVDKLGYTPNLAASALAAAQSTRIALIYS
DPSGAYLRELLLGVLRVASRTPIQLVIDCWDDLDADAERKAARKLAKGVAGVILPPPLCESKAAVLELVRAKVPVVAIAS
NYFSPDVACVRIDEFTAAKEITEHLIAQGHTRIGYIAGHPNLSASTRRFEGFQAALEDAGLRLDLHLVQPGDYTYKSGLV
AAEKLLARKCRPSAIFASNDDMAAAAISVAHRRGLDVPRDLSVVGFDDTSAATAVWPEITTVQQPIAAMADAALDILLKT
IRAKERTAKMVDHVVAHLLVKRDSVAAPTADDAVE

Sequences:

>Translated_355_residues
MDKVRKSVRRTSRATTIDEVAALAKVSPMTVSRVVNNTGGVRDATRERVMRAVDKLGYTPNLAASALAAAQSTRIALIYS
DPSGAYLRELLLGVLRVASRTPIQLVIDCWDDLDADAERKAARKLAKGVAGVILPPPLCESKAAVLELVRAKVPVVAIAS
NYFSPDVACVRIDEFTAAKEITEHLIAQGHTRIGYIAGHPNLSASTRRFEGFQAALEDAGLRLDLHLVQPGDYTYKSGLV
AAEKLLARKCRPSAIFASNDDMAAAAISVAHRRGLDVPRDLSVVGFDDTSAATAVWPEITTVQQPIAAMADAALDILLKT
IRAKERTAKMVDHVVAHLLVKRDSVAAPTADDAVE
>Mature_355_residues
MDKVRKSVRRTSRATTIDEVAALAKVSPMTVSRVVNNTGGVRDATRERVMRAVDKLGYTPNLAASALAAAQSTRIALIYS
DPSGAYLRELLLGVLRVASRTPIQLVIDCWDDLDADAERKAARKLAKGVAGVILPPPLCESKAAVLELVRAKVPVVAIAS
NYFSPDVACVRIDEFTAAKEITEHLIAQGHTRIGYIAGHPNLSASTRRFEGFQAALEDAGLRLDLHLVQPGDYTYKSGLV
AAEKLLARKCRPSAIFASNDDMAAAAISVAHRRGLDVPRDLSVVGFDDTSAATAVWPEITTVQQPIAAMADAALDILLKT
IRAKERTAKMVDHVVAHLLVKRDSVAAPTADDAVE

Specific function: Involved in the control of degradation of B.subtilis amidophosphoribosyltransferase (purF). Probably activates the gene for a degradative protease [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=321, Percent_Identity=31.7757009345794, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1789202, Length=334, Percent_Identity=32.9341317365269, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1789068, Length=338, Percent_Identity=31.0650887573964, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1790194, Length=309, Percent_Identity=30.42071197411, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1787948, Length=339, Percent_Identity=30.6784660766962, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1788474, Length=334, Percent_Identity=32.9341317365269, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1786540, Length=348, Percent_Identity=29.3103448275862, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI48994940, Length=327, Percent_Identity=28.1345565749235, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787580, Length=337, Percent_Identity=25.5192878338279, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787906, Length=257, Percent_Identity=31.1284046692607, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1789456, Length=325, Percent_Identity=26.1538461538462, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786268, Length=312, Percent_Identity=25.6410256410256, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1790715, Length=331, Percent_Identity=23.8670694864048, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38046; Mature: 38046

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKVRKSVRRTSRATTIDEVAALAKVSPMTVSRVVNNTGGVRDATRERVMRAVDKLGYTP
CCHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCC
NLAASALAAAQSTRIALIYSDPSGAYLRELLLGVLRVASRTPIQLVIDCWDDLDADAERK
CHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHH
AARKLAKGVAGVILPPPLCESKAAVLELVRAKVPVVAIASNYFSPDVACVRIDEFTAAKE
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEHHHHHHHH
ITEHLIAQGHTRIGYIAGHPNLSASTRRFEGFQAALEDAGLRLDLHLVQPGDYTYKSGLV
HHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHH
AAEKLLARKCRPSAIFASNDDMAAAAISVAHRRGLDVPRDLSVVGFDDTSAATAVWPEIT
HHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHCCCHH
TVQQPIAAMADAALDILLKTIRAKERTAKMVDHVVAHLLVKRDSVAAPTADDAVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MDKVRKSVRRTSRATTIDEVAALAKVSPMTVSRVVNNTGGVRDATRERVMRAVDKLGYTP
CCHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCC
NLAASALAAAQSTRIALIYSDPSGAYLRELLLGVLRVASRTPIQLVIDCWDDLDADAERK
CHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHH
AARKLAKGVAGVILPPPLCESKAAVLELVRAKVPVVAIASNYFSPDVACVRIDEFTAAKE
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEHHHHHHHH
ITEHLIAQGHTRIGYIAGHPNLSASTRRFEGFQAALEDAGLRLDLHLVQPGDYTYKSGLV
HHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHH
AAEKLLARKCRPSAIFASNDDMAAAAISVAHRRGLDVPRDLSVVGFDDTSAATAVWPEIT
HHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHCCCHH
TVQQPIAAMADAALDILLKTIRAKERTAKMVDHVVAHLLVKRDSVAAPTADDAVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8407808; 9353932; 9384377 [H]