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The map label for this gene is tatD [H]

Identifier: 84625757

GI number: 84625757

Start: 4624715

End: 4625527

Strand: Reverse

Name: tatD [H]

Synonym: XOO_4100

Alternate gene names: 84625757

Gene position: 4625527-4624715 (Counterclockwise)

Preceding gene: 84625759

Following gene: 84625755

Centisome position: 93.63

GC content: 65.56

Gene sequence:

>813_bases
ATGCAATTGATCGATATCGGCGCCAACCTCACCCACGACTCGTTCGACCGTGATCGCGATGCGGTGCTGCAGCGCGCACG
CGATGCCGGCGTGGGGCAGCTGGTGATCACCGGCGCTAGCCGCGAGCATTCGCCACTGGCCTTGCAACTGGCGCAGCAAC
ACCCCGGATTCCTGTACGCCACCGCCGGTGTGCACCCGCACCATGCGGTGGAATGCACCGCCGAATGCGAAGCGGAAATG
CGGACGCTGCAGGCGCATTCGCAGGTGGTGGCCGTGGGTGAGTGCGGGCTGGATTACTTCCGCGATTTCGCGCCGCGCCC
GGCGCAGCACAAGGCGTTCGAACGCCAGCTGCAGTTGGCTGCCGATAACGGCAAGCCGCTGTTCCTGCACCAGCGCGACG
CGCATGAAGATTTCCTCGCCATCATGCGCAGCTTCGAAGGCCGCCTGGGTGCCGCGGTGGTGCATTGCTTCACCGGCACG
CGCGAGGAACTGTTTGCGTATCTGGACCGCGATTACTACATCGGCATCACCGGCTGGCTCTGCGACGAACGCCGCGGCGC
GCATCTGCGCGAGCTGGTGCGCAACATTCCGGCCAACCGCTTGATGATCGAGACCGATGCGCCGTACCTGCTGCCGCGCA
CGCTCAAGCCGATGCCCAAGGACCGCCGCAACGAGCCGATGTTCCTGTCGCATATCGTGGAAGAACTGGCACGCGATCGT
GGCGAAGATGTGGCCGTGACCGCTGCCAACAGCACGGCAGCGGCACGTGCCTTCTTCCGCTTGCCGGAGCCTGCCGGCGC
GAAGGGCAGCTGA

Upstream 100 bases:

>100_bases
GGGGACGGCGCGAGCCACCCGAGCCACCCGACCCAAGCAGGCATGCAAACCGCCACGCTCGTTACACTTACCCGGCTCAC
TCCCACACGACACACGCAAC

Downstream 100 bases:

>100_bases
CAAAATGTAGCGAGCAGTCGTCAGGTGGGTGCGGCCGGCACGCAGGGATTGCAGCGCTCGCGTGCTACATGCCGCACCGA
GCACCGGCCACGTCCGACTG

Product: type V secretory pathway protein

Products: NA

Alternate protein names: DNase tatD [H]

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MQLIDIGANLTHDSFDRDRDAVLQRARDAGVGQLVITGASREHSPLALQLAQQHPGFLYATAGVHPHHAVECTAECEAEM
RTLQAHSQVVAVGECGLDYFRDFAPRPAQHKAFERQLQLAADNGKPLFLHQRDAHEDFLAIMRSFEGRLGAAVVHCFTGT
REELFAYLDRDYYIGITGWLCDERRGAHLRELVRNIPANRLMIETDAPYLLPRTLKPMPKDRRNEPMFLSHIVEELARDR
GEDVAVTAANSTAAARAFFRLPEPAGAKGS

Sequences:

>Translated_270_residues
MQLIDIGANLTHDSFDRDRDAVLQRARDAGVGQLVITGASREHSPLALQLAQQHPGFLYATAGVHPHHAVECTAECEAEM
RTLQAHSQVVAVGECGLDYFRDFAPRPAQHKAFERQLQLAADNGKPLFLHQRDAHEDFLAIMRSFEGRLGAAVVHCFTGT
REELFAYLDRDYYIGITGWLCDERRGAHLRELVRNIPANRLMIETDAPYLLPRTLKPMPKDRRNEPMFLSHIVEELARDR
GEDVAVTAANSTAAARAFFRLPEPAGAKGS
>Mature_270_residues
MQLIDIGANLTHDSFDRDRDAVLQRARDAGVGQLVITGASREHSPLALQLAQQHPGFLYATAGVHPHHAVECTAECEAEM
RTLQAHSQVVAVGECGLDYFRDFAPRPAQHKAFERQLQLAADNGKPLFLHQRDAHEDFLAIMRSFEGRLGAAVVHCFTGT
REELFAYLDRDYYIGITGWLCDERRGAHLRELVRNIPANRLMIETDAPYLLPRTLKPMPKDRRNEPMFLSHIVEELARDR
GEDVAVTAANSTAAARAFFRLPEPAGAKGS

Specific function: Shows DNase activity [H]

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=297, Percent_Identity=36.026936026936, Blast_Score=148, Evalue=6e-36,
Organism=Homo sapiens, GI225903439, Length=253, Percent_Identity=36.7588932806324, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI225903424, Length=197, Percent_Identity=38.0710659898477, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI110349730, Length=269, Percent_Identity=26.3940520446097, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI110349734, Length=269, Percent_Identity=26.7657992565056, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI226061853, Length=275, Percent_Identity=26.5454545454545, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI226061614, Length=261, Percent_Identity=26.4367816091954, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI226061595, Length=228, Percent_Identity=26.3157894736842, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI48994985, Length=257, Percent_Identity=50.5836575875486, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI1787342, Length=256, Percent_Identity=31.25, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI87082439, Length=256, Percent_Identity=30.078125, Blast_Score=93, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17559024, Length=281, Percent_Identity=38.7900355871886, Blast_Score=206, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI71980746, Length=269, Percent_Identity=26.0223048327138, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17565396, Length=172, Percent_Identity=33.7209302325581, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24648690, Length=274, Percent_Identity=38.3211678832117, Blast_Score=187, Evalue=9e-48,
Organism=Drosophila melanogaster, GI221330018, Length=280, Percent_Identity=34.6428571428571, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24586117, Length=253, Percent_Identity=34.3873517786561, Blast_Score=113, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.- [C]

Molecular weight: Translated: 30132; Mature: 30132

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS01090 TATD_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLIDIGANLTHDSFDRDRDAVLQRARDAGVGQLVITGASREHSPLALQLAQQHPGFLYA
CEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEHHCCCCEEEE
TAGVHPHHAVECTAECEAEMRTLQAHSQVVAVGECGLDYFRDFAPRPAQHKAFERQLQLA
ECCCCCCHHEEEHHHHHHHHHHHHHHHCEEEEHHCCHHHHHHCCCCCHHHHHHHHHHHHC
ADNGKPLFLHQRDAHEDFLAIMRSFEGRLGAAVVHCFTGTREELFAYLDRDYYIGITGWL
CCCCCEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHCCCEEEEEEEEE
CDERRGAHLRELVRNIPANRLMIETDAPYLLPRTLKPMPKDRRNEPMFLSHIVEELARDR
CCCCCCHHHHHHHHHCCCCEEEEECCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
GEDVAVTAANSTAAARAFFRLPEPAGAKGS
CCCEEEEECCCHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MQLIDIGANLTHDSFDRDRDAVLQRARDAGVGQLVITGASREHSPLALQLAQQHPGFLYA
CEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEHHCCCCEEEE
TAGVHPHHAVECTAECEAEMRTLQAHSQVVAVGECGLDYFRDFAPRPAQHKAFERQLQLA
ECCCCCCHHEEEHHHHHHHHHHHHHHHCEEEEHHCCHHHHHHCCCCCHHHHHHHHHHHHC
ADNGKPLFLHQRDAHEDFLAIMRSFEGRLGAAVVHCFTGTREELFAYLDRDYYIGITGWL
CCCCCEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHCCCEEEEEEEEE
CDERRGAHLRELVRNIPANRLMIETDAPYLLPRTLKPMPKDRRNEPMFLSHIVEELARDR
CCCCCCHHHHHHHHHCCCCEEEEECCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
GEDVAVTAANSTAAARAFFRLPEPAGAKGS
CCCEEEEECCCHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Mg [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1584020; 9649434; 1379743; 9278503; 10747959 [H]