Click here to switch to the map view.

The map label for this gene is pntB [H]

Identifier: 84625087

GI number: 84625087

Start: 3888538

End: 3890031

Strand: Reverse

Name: pntB [H]

Synonym: XOO_3430

Alternate gene names: 84625087

Gene position: 3890031-3888538 (Counterclockwise)

Preceding gene: 84625088

Following gene: 84625083

Centisome position: 78.74

GC content: 64.32

Gene sequence:

>1494_bases
ATGAACCTGTCCACCGCCGAATTGCTGTCGTGGTTTGTCAAAACCAGTTACCTGGTCGCCGCGACCTTGTTCCTGCCCGA
GCTGCACAACGTGCCGCTGATTCTGGCGGCGCTGGCGATCGGTACCGGCGTGGCGTGGTGGTCGGCCAAGAAGGTGGCCA
TCACCGACATGCCGCAGATGGTGGCGCTCTACAACGGCATGGGCGGCGGGTCGGCGGCGGCGATCGGGGCGGTGGAGCTG
CTGCGGTTTTCGTTTTTCGCCAATTGCGACACGGCGCACTGGAGCGCGCAGGCCATTGCCGAACTGGCGGCGCGGCGGCC
GGACACCACCGCGGTGGCGGTGGCGGTGGCGGTGATCGGCTCGGCGATCGGCGCGGTGTCGCTGTCGGGGTCGATCATCG
CGTGGGCCAAGCTCGACGGTCGGCTCGACCGGCGCGTGACCTTCCCCGGCCAGCAGGTTTTCAATCTGGTGGTGGCCGTG
GCGGTGCTGGTGCTCGGCATCTGGGCGGCGAGCAGTCTGCAGCCGCTGGCGATCATCGCGTTCTTTGTGGCGGCGCTGGC
GCTGGGCGTGCTGATGACGCTACCGATCGGCGGCGCCGACATGCCGGTAGTGATTTCGCTTTACAACGCGTTTACCGGGT
TGGCGGTGGCGTTCGAGGGCTATGTGCTGGGCAATGAAGCGCTGATCATCGCCGGCATGATGGTGGGTGCGGCAGGCATT
TTGCTGACGCGGTTGATGGCCAAGGCGATGAATCGGCCGATCAGCGGCGTGCTGTTTTCCAACTTCGGCGGTGGCGGGCA
GGCGCAAGAAATCAGCGGGACGCAAAAGCCGATCGAGGCCGGCGATGTGGCGGCGATGATGGCCTTTGCCGAGCGCGTGG
TGATCGTGCCCGGTTACGGCATGGCAGTGGCGCAGGCGCAGCACAAAATCTGGGAACTGGCGCAGCGGTTGATCGCACGC
GGGGCCAAGGTCAAGTTTGCGATCCATCCAGTCGCCGGGCGCATGCCTGGGCACATGAACGTGCTGCTGGCCGAAGCCGG
CGTGCCCTACGATCTGATCGCCGATATGGACGACATCAATCCGGAATTCGCGAGCACCGATGTGTCATTGGTGATCGGTG
CCAACGACGTGGTCAACCCGGTGGCCAAGACCGATCCGGCCAGCCCGATCTACGGCATGCCGATCCTGGACGTGGTCAAT
TCGCGCAACACGGTGGTGATCAAGCGCGGCAAGGGCACGGGGTTTGCCGGCATCGAGAATGCGCTGTTCTACGCCGACAA
CACCCGCATGCTGTACGGCGATGGGGCGGAAGCAGCCGGCGCGCTCGTGAGCGAATTGAAAGCGCTGGATGGCGGCGGGC
TTGAGTGTTGGTGTGTCGCCAGGTGCGCTCAGATGCTTAGAACCTGTTCACGATCTCCTGAGCAGCAGTGCCAGGAACGC
CAGATGGATGAACTGCAAGCTGGTATTGAGCCTTCGCTCGCAGTTCTTCCATAG

Upstream 100 bases:

>100_bases
TGGCGCTGGGCGCGGGTAACGCAGCCGGCGGTTACGTGGTCACCGAGCGGATGCTGGAGATGTTCAAGTCCAGCAAGAAG
CCGCCGGGCAGGGATGCGTC

Downstream 100 bases:

>100_bases
CCTCCGGTTCTTCTCCAGCCAGGCAAAGCTGCGTTCGACACTCCAGCGCTTGGGCATGACCTTGAAGGTATGCAGCTCGC
TGCGCTTGGCAATCTGTACG

Product: pyridine nucleotide transhydrogenase subunit beta

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Pyridine nucleotide transhydrogenase subunit beta [H]

Number of amino acids: Translated: 497; Mature: 497

Protein sequence:

>497_residues
MNLSTAELLSWFVKTSYLVAATLFLPELHNVPLILAALAIGTGVAWWSAKKVAITDMPQMVALYNGMGGGSAAAIGAVEL
LRFSFFANCDTAHWSAQAIAELAARRPDTTAVAVAVAVIGSAIGAVSLSGSIIAWAKLDGRLDRRVTFPGQQVFNLVVAV
AVLVLGIWAASSLQPLAIIAFFVAALALGVLMTLPIGGADMPVVISLYNAFTGLAVAFEGYVLGNEALIIAGMMVGAAGI
LLTRLMAKAMNRPISGVLFSNFGGGGQAQEISGTQKPIEAGDVAAMMAFAERVVIVPGYGMAVAQAQHKIWELAQRLIAR
GAKVKFAIHPVAGRMPGHMNVLLAEAGVPYDLIADMDDINPEFASTDVSLVIGANDVVNPVAKTDPASPIYGMPILDVVN
SRNTVVIKRGKGTGFAGIENALFYADNTRMLYGDGAEAAGALVSELKALDGGGLECWCVARCAQMLRTCSRSPEQQCQER
QMDELQAGIEPSLAVLP

Sequences:

>Translated_497_residues
MNLSTAELLSWFVKTSYLVAATLFLPELHNVPLILAALAIGTGVAWWSAKKVAITDMPQMVALYNGMGGGSAAAIGAVEL
LRFSFFANCDTAHWSAQAIAELAARRPDTTAVAVAVAVIGSAIGAVSLSGSIIAWAKLDGRLDRRVTFPGQQVFNLVVAV
AVLVLGIWAASSLQPLAIIAFFVAALALGVLMTLPIGGADMPVVISLYNAFTGLAVAFEGYVLGNEALIIAGMMVGAAGI
LLTRLMAKAMNRPISGVLFSNFGGGGQAQEISGTQKPIEAGDVAAMMAFAERVVIVPGYGMAVAQAQHKIWELAQRLIAR
GAKVKFAIHPVAGRMPGHMNVLLAEAGVPYDLIADMDDINPEFASTDVSLVIGANDVVNPVAKTDPASPIYGMPILDVVN
SRNTVVIKRGKGTGFAGIENALFYADNTRMLYGDGAEAAGALVSELKALDGGGLECWCVARCAQMLRTCSRSPEQQCQER
QMDELQAGIEPSLAVLP
>Mature_497_residues
MNLSTAELLSWFVKTSYLVAATLFLPELHNVPLILAALAIGTGVAWWSAKKVAITDMPQMVALYNGMGGGSAAAIGAVEL
LRFSFFANCDTAHWSAQAIAELAARRPDTTAVAVAVAVIGSAIGAVSLSGSIIAWAKLDGRLDRRVTFPGQQVFNLVVAV
AVLVLGIWAASSLQPLAIIAFFVAALALGVLMTLPIGGADMPVVISLYNAFTGLAVAFEGYVLGNEALIIAGMMVGAAGI
LLTRLMAKAMNRPISGVLFSNFGGGGQAQEISGTQKPIEAGDVAAMMAFAERVVIVPGYGMAVAQAQHKIWELAQRLIAR
GAKVKFAIHPVAGRMPGHMNVLLAEAGVPYDLIADMDDINPEFASTDVSLVIGANDVVNPVAKTDPASPIYGMPILDVVN
SRNTVVIKRGKGTGFAGIENALFYADNTRMLYGDGAEAAGALVSELKALDGGGLECWCVARCAQMLRTCSRSPEQQCQER
QMDELQAGIEPSLAVLP

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=429, Percent_Identity=39.3939393939394, Blast_Score=291, Evalue=7e-79,
Organism=Homo sapiens, GI122939153, Length=429, Percent_Identity=39.3939393939394, Blast_Score=291, Evalue=7e-79,
Organism=Escherichia coli, GI1787886, Length=435, Percent_Identity=41.8390804597701, Blast_Score=325, Evalue=5e-90,
Organism=Caenorhabditis elegans, GI17550456, Length=435, Percent_Identity=38.3908045977011, Blast_Score=295, Evalue=5e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 51956; Mature: 51956

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLSTAELLSWFVKTSYLVAATLFLPELHNVPLILAALAIGTGVAWWSAKKVAITDMPQM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHECCCCEEEECCCHHH
VALYNGMGGGSAAAIGAVELLRFSFFANCDTAHWSAQAIAELAARRPDTTAVAVAVAVIG
HHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
SAIGAVSLSGSIIAWAKLDGRLDRRVTFPGQQVFNLVVAVAVLVLGIWAASSLQPLAIIA
HHHHHEEECCCEEEEEECCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
FFVAALALGVLMTLPIGGADMPVVISLYNAFTGLAVAFEGYVLGNEALIIAGMMVGAAGI
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHEECEEECCCHHHHHHHHHHHHHH
LLTRLMAKAMNRPISGVLFSNFGGGGQAQEISGTQKPIEAGDVAAMMAFAERVVIVPGYG
HHHHHHHHHHCCCCCEEEEECCCCCCCCHHCCCCCCCCCHHHHHHHHHHHCCEEEECCCC
MAVAQAQHKIWELAQRLIARGAKVKFAIHPVAGRMPGHMNVLLAEAGVPYDLIADMDDIN
HHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEEEEECCCCCHHHHCCCHHCC
PEFASTDVSLVIGANDVVNPVAKTDPASPIYGMPILDVVNSRNTVVIKRGKGTGFAGIEN
CCCCCCCEEEEECCCHHHCCHHCCCCCCCCCCCHHHHHHCCCCEEEEECCCCCCCCCCCC
ALFYADNTRMLYGDGAEAAGALVSELKALDGGGLECWCVARCAQMLRTCSRSPEQQCQER
EEEEECCCEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
QMDELQAGIEPSLAVLP
HHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MNLSTAELLSWFVKTSYLVAATLFLPELHNVPLILAALAIGTGVAWWSAKKVAITDMPQM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHECCCCEEEECCCHHH
VALYNGMGGGSAAAIGAVELLRFSFFANCDTAHWSAQAIAELAARRPDTTAVAVAVAVIG
HHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
SAIGAVSLSGSIIAWAKLDGRLDRRVTFPGQQVFNLVVAVAVLVLGIWAASSLQPLAIIA
HHHHHEEECCCEEEEEECCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
FFVAALALGVLMTLPIGGADMPVVISLYNAFTGLAVAFEGYVLGNEALIIAGMMVGAAGI
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHEECEEECCCHHHHHHHHHHHHHH
LLTRLMAKAMNRPISGVLFSNFGGGGQAQEISGTQKPIEAGDVAAMMAFAERVVIVPGYG
HHHHHHHHHHCCCCCEEEEECCCCCCCCHHCCCCCCCCCHHHHHHHHHHHCCEEEECCCC
MAVAQAQHKIWELAQRLIARGAKVKFAIHPVAGRMPGHMNVLLAEAGVPYDLIADMDDIN
HHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEEEEECCCCCHHHHCCCHHCC
PEFASTDVSLVIGANDVVNPVAKTDPASPIYGMPILDVVNSRNTVVIKRGKGTGFAGIEN
CCCCCCCEEEEECCCHHHCCHHCCCCCCCCCCCHHHHHHCCCCEEEEECCCCCCCCCCCC
ALFYADNTRMLYGDGAEAAGALVSELKALDGGGLECWCVARCAQMLRTCSRSPEQQCQER
EEEEECCCEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
QMDELQAGIEPSLAVLP
HHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]