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The map label for this gene is rpoB [H]

Identifier: 84625051

GI number: 84625051

Start: 3852870

End: 3857021

Strand: Reverse

Name: rpoB [H]

Synonym: XOO_3394

Alternate gene names: 84625051

Gene position: 3857021-3852870 (Counterclockwise)

Preceding gene: 84625052

Following gene: 84625050

Centisome position: 78.07

GC content: 61.75

Gene sequence:

>4152_bases
ATGACGTCTTATTCGTTCACCGAAAAAAAGCGTATCCGCAAGGATTTCGGTAAGCAGCGCTCGATTCTCGAAGTGCCGTT
TCTGCTTGCCATCCAGGTGGATTCCTACCGCGAATTCCTGCAGGAAGATGTGGAGTCGACCAAGCGCAAGGACCTCGGTC
TGCACGCGGCATTGAAGTCGGTGTTCCCGATTTCCAGCTACAGCGGCAACGCTGCGCTGGAGTACGTCGGTTACAAGTTG
GGTCAGCCGGTGTTCGACGAGCGCGAATGCCGTCAGCGTGGCATGAGCTATGGCGCGCCGCTGCGCGTGACCGTGCGCCT
GGTGATCTACGACCGCGAGTCGTCCACCAAGGCGATCAAGTACGTGAAGGAGCAGGAGGTCTATCTCGGCGAAATTCCGC
TGATGACCGGCAACGGTACCTTCATCGTCAACGGCACCGAGCGTGTGATCGTGTCGCAGCTGCATCGCTCGCCGGGCGTG
TTTTTCGACCACGACCGTGGCAAGACCCACAGCTCGGGCAAGCTGCTGTACAGCGCCCGCATCATTCCGTACCGCGGTTC
CTGGTTGGACTTCGAGTTCGACCCGAAGGATGCGCTGTTCACCCGTATCGACCGTCGCCGCAAGTTGCCGGTGTCGATCC
TGCTGCGCGCGCTCGGCTACAACAACGAAGAAATGCTGGCCGAGTTCTTCGAGATCAACACCTTCCACATCAATCCGGAC
GAAGGCGTGCAGCTGGAGCTGGTACCGGAGCGTCTGCGTGGCGAAACGCTGAACTTCGACCTGGCCGATGGCGATAAGGT
CATCGTGGAAGCCGGTAAGCGCATCACCGCGCGTCACGTCAAGCAACTGGAAGCCGCCGGCGTTGCCGCGCTGGCCGTGC
CGGACGACTACCTGGTCGGCCGCATCCTGTCGCACGACGTGGTCGATGGCTCCACCGGCGAACTGCTGGCCAATGCCAAC
GACGAGATCAGCGAAGACCAACTGACCGCGTTCCGCAAGGCTGGCGTCGATGCGGTCGGCACCCTGTGGGTGAACGATCT
GGATCGTGGTCCGTACCTGTCCAACACCTTGCGCATCGATCCGACCAAGACGCAGCTGGAAGCGCTGGTCGAAATCTACC
GCATGATGCGTCCGGGCGAGCCGCCGACCAAGGAAGCCGCGCAGAACCTGTTCCACAACCTGTTCTTCACCTTCGAGCGC
TACGACCTGTCCACGGTCGGCCGCATGAAGTTCAACCGTCGCGTCGGCCGCAAGGACGTGCTGGGCGAGTCGGTGCTGTA
CGACAAGAAGTATTTTGCCGAGCGTAACGACGAAGAATCCAAGCGCCTGGTCGCCGAGCACACCGACACCTCCGACATCC
TGGAAGTGATCAAGGTCCTGACCGAGATCCGCAATGGTCGCGGCGTGGTCGATGACATCGATCACCTGGGCAACCGTCGC
GTGCGTTCGGTCGGCGAAATGGCCGAGAACGTGTTCCGCGTAGGCCTGGTCCGCGTCGAGCGTGCGGTCAAGGAGCGTCT
GTCGATGGCGGAGTCGGAAGGTCTGACCCCGCAGGAATTGATCAACGCCAAGCCGGTGGCTGCAGCGATCAAGGAATTCT
TCGGCTCCTCGCAGCTGTCGCAGTTCATGGACCAGAACAACCCACTGTCGGAAGTGACGCACAAGCGTCGCGTCTCCGCA
CTGGGCCCGGGCGGTCTGACCCGCGAACGCGCCGGCTTCGAAGTGCGCGACGTGCATCCGACCCATTATGGCCGCGTCTG
CACCATCGAAACGCCGGAAGGCCCGAACATCGGCCTGATCAACTCGCTGGCCGTGTTCGCCCGCACCAACCAGTACGGCT
TCCTCGAGACGCCGTACCGTAAGGTGCTGGACGGCAAGGTCTCCGACGACGTCGAATACCTCTCGGCGATCGAAGAAAAC
GAGTACGTGATCGCCCAGGCGAACGCGCTGACCGATGCAAAGAACATGCTCACCGAGCAGTTCGTGCCGTGCCGGTTCCA
GGGCGAATCGCTGTTGAAACCGCCGTCCGAAGTGCACTTCATGGACGTTTCGCCGATGCAGACCGTTTCGGTCGCAGCGG
CGCTGGTGCCGTTCCTTGAGCACGACGACGCCAACCGCGCACTGATGGGCGCCAACATGCAGCGCCAGGCCGTGCCGACG
CTGCGTTCGCAGAAGCCGCTTGTCGGTACCGGCATCGAGCGTGCGGTTGCGCGCGACTCGGGCGTGACCGTCAATGCGCT
GCGTGGTGGCGTGATCGAGCAGATCGACGCCGCTCGTATCGTGGTCAAGGTCAATGAGGCAGAAATTGGCGGCGGCACCG
ATGCCGGCGTGGATATCTACAACCTGATCAAGTACACCCGCTCCAACCAGAACACCTGCATCAACCAGCGTCCGCTGGTG
AATGTGGGTGACGTGATCGCGCGCGGCGACGTGCTGGCCGACGGCCCGTCCACCGACATCGGTGAACTGGCGCTGGGTCA
GAACATGCTGATCGCCTTCATGCCGTGGAACGGCTACAACTTCGAAGACTCCATCCTGCTCTCCGAACGCGTGGTGGAAG
AAGATCGTTACACCACGATCCACATCGAAGAGCTGACCTGCGTTGCGCGCGACACCAAGCTGGGGCCGGAGGAAATTTCC
GCAGACATCCCGAACGTGTCCGAGCAGGCGTTGAACCGTCTGGACGAGAGTGGCGTGGTGTACATTGGTGCGGAAGTACG
CGCTGGCGACATCATGGTCGGCAAGGTCACGCCGAAGGGCGAAAGCCAGCTGACCCCGGAAGAAAAGCTGCTGCGTGCCA
TCTTCGGTGAGAAGGCGTCCGACGTGAAGGACAGCTCGCTGCGCGTGCCCCCGGGCATGGATGGCACCGTCATCGACGTG
CAGGTCTTCACTCGCGACGGCATCGAGAAGGACAAGCGTGCGCGTCAGATCGAGGAAAACGAGATCAAGCGCGTCAAGAA
GGACTTCGACGACCAGTTCCGCATCCTGGAAGCGGCCATCTACGCCCGTCTGCGCTCGCAGATCGTGGGCAAGGTCGCCA
ACGGTGGCGCGAACCTGAAGAAGGGCGACTCCGTCACCGACGCCTACCTGGACGGGCTGAAGAAGTCCGATTGGTTCCAG
CTGCGCATGAAGGACGAGGACGCTGCCGACGCCATCGAGCGTGCGCAGAAGCAGATCCAGGCGCACGAGAAGGAATTCGA
AGCACGGTTTGCCGACAAGCGCGGCAAGATCACCCAGGGCGACGACCTCGCGCCGGGCGTGCTGAAGATGGTCAAGGTGT
TCCTGGCGGTGAAGCGCCGCATCCAGCCGGGCGACAAGATGGCAGGCCGCCACGGCAACAAGGGTGTGGTCTCCAACGTG
GTGCCGGTGGAAGACATGCCGTACATGGCCACCGGTGAGTCGGTCGACATCGTGTTGAACCCGCTCGGCGTGCCGTCGCG
TATGAACATCGGCCAGATTCTGGAAGTGCATCTGGGCTGGGCCGCCAAGGGCCTGGGTCGCAAGATCCAGCGCATGCTGG
AAGCCCAGGCCGCCGTCAGCGAACTGCGCAAGTTCCTGGACGACATCTACAACCACGACAACGCGATCAATGCGCAGCGC
GTGGATCTGTCGCAGTTCAGCGATGAGGAATTGCTCAACCTGGGCAAGAACCTGATCGACGGCGTACCGATGGCCACCCC
GGTGTTCGACGGCGCCAGCGAAGCGGAAATCAAGCGCATGCTGGAACTGGCCGACCTGCCGCAGAGCGGTCAGACCCAGC
TGTACGACGGTCGCACTGGCGAAGCGTTCGATCGCAAGACCACGGTCGGCTACATGCACTACCTGAAGTTGAACCACTTG
GTCGACGACAAGATGCATGCACGTTCGACTGGCCCGTACTCGCTCGTCACTCAGCAGCCGCTGGGCGGCAAGGCGCAATT
CGGTGGTCAGCGCTTCGGCGAAATGGAAGTCTGGGCGCTGGAAGCCTACGGCGCTGCCTACACCCTGCAGGAAATGCTGA
CGGTGAAGTCCGACGACGTGCAGGGCCGCAACCAGATGTACAAGAACATCGTCGATGGTGAGCACGAGATGGTCGCAGGA
ATGCCGGAATCCTTCAACGTGTTGGTGAAGGAAATCCGTTCGCTGGCGATCCACATGGAACTGGAAGAGTAA

Upstream 100 bases:

>100_bases
AAGGCGTGCTGGTGCCGGCAATACCAGCGACTTCCAACTGACAATTTTGTTATTTCAGGGCCGCTGCGACGCGGCCCCCG
CAGCCTAGGGTGAAGACCTC

Downstream 100 bases:

>100_bases
GGGCAGGGCCCGGTCAGGGGCGGGCAACCCGGAAGAGACGAGCGCCCAGTGCGTTCGCTCTTCCAGGGTACTGTTTCCTG
ATCCCAGTCCCGATCAAAGC

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta [H]

Number of amino acids: Translated: 1383; Mature: 1382

Protein sequence:

>1383_residues
MTSYSFTEKKRIRKDFGKQRSILEVPFLLAIQVDSYREFLQEDVESTKRKDLGLHAALKSVFPISSYSGNAALEYVGYKL
GQPVFDERECRQRGMSYGAPLRVTVRLVIYDRESSTKAIKYVKEQEVYLGEIPLMTGNGTFIVNGTERVIVSQLHRSPGV
FFDHDRGKTHSSGKLLYSARIIPYRGSWLDFEFDPKDALFTRIDRRRKLPVSILLRALGYNNEEMLAEFFEINTFHINPD
EGVQLELVPERLRGETLNFDLADGDKVIVEAGKRITARHVKQLEAAGVAALAVPDDYLVGRILSHDVVDGSTGELLANAN
DEISEDQLTAFRKAGVDAVGTLWVNDLDRGPYLSNTLRIDPTKTQLEALVEIYRMMRPGEPPTKEAAQNLFHNLFFTFER
YDLSTVGRMKFNRRVGRKDVLGESVLYDKKYFAERNDEESKRLVAEHTDTSDILEVIKVLTEIRNGRGVVDDIDHLGNRR
VRSVGEMAENVFRVGLVRVERAVKERLSMAESEGLTPQELINAKPVAAAIKEFFGSSQLSQFMDQNNPLSEVTHKRRVSA
LGPGGLTRERAGFEVRDVHPTHYGRVCTIETPEGPNIGLINSLAVFARTNQYGFLETPYRKVLDGKVSDDVEYLSAIEEN
EYVIAQANALTDAKNMLTEQFVPCRFQGESLLKPPSEVHFMDVSPMQTVSVAAALVPFLEHDDANRALMGANMQRQAVPT
LRSQKPLVGTGIERAVARDSGVTVNALRGGVIEQIDAARIVVKVNEAEIGGGTDAGVDIYNLIKYTRSNQNTCINQRPLV
NVGDVIARGDVLADGPSTDIGELALGQNMLIAFMPWNGYNFEDSILLSERVVEEDRYTTIHIEELTCVARDTKLGPEEIS
ADIPNVSEQALNRLDESGVVYIGAEVRAGDIMVGKVTPKGESQLTPEEKLLRAIFGEKASDVKDSSLRVPPGMDGTVIDV
QVFTRDGIEKDKRARQIEENEIKRVKKDFDDQFRILEAAIYARLRSQIVGKVANGGANLKKGDSVTDAYLDGLKKSDWFQ
LRMKDEDAADAIERAQKQIQAHEKEFEARFADKRGKITQGDDLAPGVLKMVKVFLAVKRRIQPGDKMAGRHGNKGVVSNV
VPVEDMPYMATGESVDIVLNPLGVPSRMNIGQILEVHLGWAAKGLGRKIQRMLEAQAAVSELRKFLDDIYNHDNAINAQR
VDLSQFSDEELLNLGKNLIDGVPMATPVFDGASEAEIKRMLELADLPQSGQTQLYDGRTGEAFDRKTTVGYMHYLKLNHL
VDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVQGRNQMYKNIVDGEHEMVAG
MPESFNVLVKEIRSLAIHMELEE

Sequences:

>Translated_1383_residues
MTSYSFTEKKRIRKDFGKQRSILEVPFLLAIQVDSYREFLQEDVESTKRKDLGLHAALKSVFPISSYSGNAALEYVGYKL
GQPVFDERECRQRGMSYGAPLRVTVRLVIYDRESSTKAIKYVKEQEVYLGEIPLMTGNGTFIVNGTERVIVSQLHRSPGV
FFDHDRGKTHSSGKLLYSARIIPYRGSWLDFEFDPKDALFTRIDRRRKLPVSILLRALGYNNEEMLAEFFEINTFHINPD
EGVQLELVPERLRGETLNFDLADGDKVIVEAGKRITARHVKQLEAAGVAALAVPDDYLVGRILSHDVVDGSTGELLANAN
DEISEDQLTAFRKAGVDAVGTLWVNDLDRGPYLSNTLRIDPTKTQLEALVEIYRMMRPGEPPTKEAAQNLFHNLFFTFER
YDLSTVGRMKFNRRVGRKDVLGESVLYDKKYFAERNDEESKRLVAEHTDTSDILEVIKVLTEIRNGRGVVDDIDHLGNRR
VRSVGEMAENVFRVGLVRVERAVKERLSMAESEGLTPQELINAKPVAAAIKEFFGSSQLSQFMDQNNPLSEVTHKRRVSA
LGPGGLTRERAGFEVRDVHPTHYGRVCTIETPEGPNIGLINSLAVFARTNQYGFLETPYRKVLDGKVSDDVEYLSAIEEN
EYVIAQANALTDAKNMLTEQFVPCRFQGESLLKPPSEVHFMDVSPMQTVSVAAALVPFLEHDDANRALMGANMQRQAVPT
LRSQKPLVGTGIERAVARDSGVTVNALRGGVIEQIDAARIVVKVNEAEIGGGTDAGVDIYNLIKYTRSNQNTCINQRPLV
NVGDVIARGDVLADGPSTDIGELALGQNMLIAFMPWNGYNFEDSILLSERVVEEDRYTTIHIEELTCVARDTKLGPEEIS
ADIPNVSEQALNRLDESGVVYIGAEVRAGDIMVGKVTPKGESQLTPEEKLLRAIFGEKASDVKDSSLRVPPGMDGTVIDV
QVFTRDGIEKDKRARQIEENEIKRVKKDFDDQFRILEAAIYARLRSQIVGKVANGGANLKKGDSVTDAYLDGLKKSDWFQ
LRMKDEDAADAIERAQKQIQAHEKEFEARFADKRGKITQGDDLAPGVLKMVKVFLAVKRRIQPGDKMAGRHGNKGVVSNV
VPVEDMPYMATGESVDIVLNPLGVPSRMNIGQILEVHLGWAAKGLGRKIQRMLEAQAAVSELRKFLDDIYNHDNAINAQR
VDLSQFSDEELLNLGKNLIDGVPMATPVFDGASEAEIKRMLELADLPQSGQTQLYDGRTGEAFDRKTTVGYMHYLKLNHL
VDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVQGRNQMYKNIVDGEHEMVAG
MPESFNVLVKEIRSLAIHMELEE
>Mature_1382_residues
TSYSFTEKKRIRKDFGKQRSILEVPFLLAIQVDSYREFLQEDVESTKRKDLGLHAALKSVFPISSYSGNAALEYVGYKLG
QPVFDERECRQRGMSYGAPLRVTVRLVIYDRESSTKAIKYVKEQEVYLGEIPLMTGNGTFIVNGTERVIVSQLHRSPGVF
FDHDRGKTHSSGKLLYSARIIPYRGSWLDFEFDPKDALFTRIDRRRKLPVSILLRALGYNNEEMLAEFFEINTFHINPDE
GVQLELVPERLRGETLNFDLADGDKVIVEAGKRITARHVKQLEAAGVAALAVPDDYLVGRILSHDVVDGSTGELLANAND
EISEDQLTAFRKAGVDAVGTLWVNDLDRGPYLSNTLRIDPTKTQLEALVEIYRMMRPGEPPTKEAAQNLFHNLFFTFERY
DLSTVGRMKFNRRVGRKDVLGESVLYDKKYFAERNDEESKRLVAEHTDTSDILEVIKVLTEIRNGRGVVDDIDHLGNRRV
RSVGEMAENVFRVGLVRVERAVKERLSMAESEGLTPQELINAKPVAAAIKEFFGSSQLSQFMDQNNPLSEVTHKRRVSAL
GPGGLTRERAGFEVRDVHPTHYGRVCTIETPEGPNIGLINSLAVFARTNQYGFLETPYRKVLDGKVSDDVEYLSAIEENE
YVIAQANALTDAKNMLTEQFVPCRFQGESLLKPPSEVHFMDVSPMQTVSVAAALVPFLEHDDANRALMGANMQRQAVPTL
RSQKPLVGTGIERAVARDSGVTVNALRGGVIEQIDAARIVVKVNEAEIGGGTDAGVDIYNLIKYTRSNQNTCINQRPLVN
VGDVIARGDVLADGPSTDIGELALGQNMLIAFMPWNGYNFEDSILLSERVVEEDRYTTIHIEELTCVARDTKLGPEEISA
DIPNVSEQALNRLDESGVVYIGAEVRAGDIMVGKVTPKGESQLTPEEKLLRAIFGEKASDVKDSSLRVPPGMDGTVIDVQ
VFTRDGIEKDKRARQIEENEIKRVKKDFDDQFRILEAAIYARLRSQIVGKVANGGANLKKGDSVTDAYLDGLKKSDWFQL
RMKDEDAADAIERAQKQIQAHEKEFEARFADKRGKITQGDDLAPGVLKMVKVFLAVKRRIQPGDKMAGRHGNKGVVSNVV
PVEDMPYMATGESVDIVLNPLGVPSRMNIGQILEVHLGWAAKGLGRKIQRMLEAQAAVSELRKFLDDIYNHDNAINAQRV
DLSQFSDEELLNLGKNLIDGVPMATPVFDGASEAEIKRMLELADLPQSGQTQLYDGRTGEAFDRKTTVGYMHYLKLNHLV
DDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVQGRNQMYKNIVDGEHEMVAGM
PESFNVLVKEIRSLAIHMELEE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family [H]

Homologues:

Organism=Homo sapiens, GI238908505, Length=299, Percent_Identity=30.7692307692308, Blast_Score=127, Evalue=7e-29,
Organism=Homo sapiens, GI238908503, Length=299, Percent_Identity=30.7692307692308, Blast_Score=127, Evalue=8e-29,
Organism=Homo sapiens, GI212286172, Length=261, Percent_Identity=31.8007662835249, Blast_Score=117, Evalue=6e-26,
Organism=Homo sapiens, GI33469941, Length=261, Percent_Identity=31.8007662835249, Blast_Score=117, Evalue=7e-26,
Organism=Homo sapiens, GI4505941, Length=253, Percent_Identity=30.8300395256917, Blast_Score=116, Evalue=2e-25,
Organism=Escherichia coli, GI1790419, Length=1380, Percent_Identity=67.7536231884058, Blast_Score=1922, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25144348, Length=253, Percent_Identity=32.4110671936759, Blast_Score=119, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI17506623, Length=235, Percent_Identity=31.063829787234, Blast_Score=113, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17552304, Length=114, Percent_Identity=36.8421052631579, Blast_Score=78, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6324725, Length=251, Percent_Identity=31.0756972111554, Blast_Score=117, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6325267, Length=254, Percent_Identity=32.6771653543307, Blast_Score=116, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6324781, Length=249, Percent_Identity=29.718875502008, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI17136446, Length=260, Percent_Identity=34.6153846153846, Blast_Score=116, Evalue=1e-25,
Organism=Drosophila melanogaster, GI17647877, Length=249, Percent_Identity=28.5140562248996, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17136444, Length=114, Percent_Identity=37.719298245614, Blast_Score=82, Evalue=2e-15,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724 [H]

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 154274; Mature: 154143

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSYSFTEKKRIRKDFGKQRSILEVPFLLAIQVDSYREFLQEDVESTKRKDLGLHAALKS
CCCCCHHHHHHHHHHHCCCCCCEECCEEEEEEEHHHHHHHHHHHHHHHHHHCHHHHHHHH
VFPISSYSGNAALEYVGYKLGQPVFDERECRQRGMSYGAPLRVTVRLVIYDRESSTKAIK
HCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHCCCCCCCCEEEEEEEEEEECCCCHHHHH
YVKEQEVYLGEIPLMTGNGTFIVNGTERVIVSQLHRSPGVFFDHDRGKTHSSGKLLYSAR
HHHHCCEEEECEEEEECCCEEEECCHHHHHHHHHHCCCCCEEECCCCCCCCCCCEEEEEE
IIPYRGSWLDFEFDPKDALFTRIDRRRKLPVSILLRALGYNNEEMLAEFFEINTFHINPD
EEEECCCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHCEEEEECCC
EGVQLELVPERLRGETLNFDLADGDKVIVEAGKRITARHVKQLEAAGVAALAVPDDYLVG
CCCEEEEECHHHCCCEEEEECCCCCEEEECCCCHHHHHHHHHHHHCCEEEEECCCHHHHH
RILSHDVVDGSTGELLANANDEISEDQLTAFRKAGVDAVGTLWVNDLDRGPYLSNTLRID
HHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCEEEHEECCCCCCCCCCCCEEEC
PTKTQLEALVEIYRMMRPGEPPTKEAAQNLFHNLFFTFERYDLSTVGRMKFNRRVGRKDV
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHH
LGESVLYDKKYFAERNDEESKRLVAEHTDTSDILEVIKVLTEIRNGRGVVDDIDHLGNRR
CCCHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHH
VRSVGEMAENVFRVGLVRVERAVKERLSMAESEGLTPQELINAKPVAAAIKEFFGSSQLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHCHHHHH
QFMDQNNPLSEVTHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRVCTIETPEGPNIGLI
HHHHCCCCHHHHHHHHHHHCCCCCCCCHHHCCCEEEECCCCCCCCEEEEECCCCCCCCHH
NSLAVFARTNQYGFLETPYRKVLDGKVSDDVEYLSAIEENEYVIAQANALTDAKNMLTEQ
HHHEEEEECCCCCCCCCCHHHHHCCCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHH
FVPCRFQGESLLKPPSEVHFMDVSPMQTVSVAAALVPFLEHDDANRALMGANMQRQAVPT
CCCCEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCEECCCCCHHHHCCH
LRSQKPLVGTGIERAVARDSGVTVNALRGGVIEQIDAARIVVKVNEAEIGGGTDAGVDIY
HHCCCCCCCCCHHHHHHCCCCCEEEHHCCCHHHHHCCEEEEEEEECCCCCCCCCCCHHHH
NLIKYTRSNQNTCINQRPLVNVGDVIARGDVLADGPSTDIGELALGQNMLIAFMPWNGYN
HHHHHHCCCCCCCCCCCCCCCHHHHHHCCCEECCCCCCCHHHHHCCCCEEEEEECCCCCC
FEDSILLSERVVEEDRYTTIHIEELTCVARDTKLGPEEISADIPNVSEQALNRLDESGVV
CCCHHHHHHHHHHCCCEEEEEEEHEEEEHHCCCCCHHHHCCCCCCHHHHHHHHCCCCCEE
YIGAEVRAGDIMVGKVTPKGESQLTPEEKLLRAIFGEKASDVKDSSLRVPPGMDGTVIDV
EEECEEEECCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEECCCCCCCCEEEE
QVFTRDGIEKDKRARQIEENEIKRVKKDFDDQFRILEAAIYARLRSQIVGKVANGGANLK
EEEECCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
KGDSVTDAYLDGLKKSDWFQLRMKDEDAADAIERAQKQIQAHEKEFEARFADKRGKITQG
CCCCHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DDLAPGVLKMVKVFLAVKRRIQPGDKMAGRHGNKGVVSNVVPVEDMPYMATGESVDIVLN
CCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCEECCCCEEEEEE
PLGVPSRMNIGQILEVHLGWAAKGLGRKIQRMLEAQAAVSELRKFLDDIYNHDNAINAQR
CCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
VDLSQFSDEELLNLGKNLIDGVPMATPVFDGASEAEIKRMLELADLPQSGQTQLYDGRTG
CCHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEECCCCC
EAFDRKTTVGYMHYLKLNHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWAL
CCCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEE
EAYGAAYTLQEMLTVKSDDVQGRNQMYKNIVDGEHEMVAGMPESFNVLVKEIRSLAIHME
EHHCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHEEEEE
LEE
ECC
>Mature Secondary Structure 
TSYSFTEKKRIRKDFGKQRSILEVPFLLAIQVDSYREFLQEDVESTKRKDLGLHAALKS
CCCCHHHHHHHHHHHCCCCCCEECCEEEEEEEHHHHHHHHHHHHHHHHHHCHHHHHHHH
VFPISSYSGNAALEYVGYKLGQPVFDERECRQRGMSYGAPLRVTVRLVIYDRESSTKAIK
HCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHCCCCCCCCEEEEEEEEEEECCCCHHHHH
YVKEQEVYLGEIPLMTGNGTFIVNGTERVIVSQLHRSPGVFFDHDRGKTHSSGKLLYSAR
HHHHCCEEEECEEEEECCCEEEECCHHHHHHHHHHCCCCCEEECCCCCCCCCCCEEEEEE
IIPYRGSWLDFEFDPKDALFTRIDRRRKLPVSILLRALGYNNEEMLAEFFEINTFHINPD
EEEECCCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHCEEEEECCC
EGVQLELVPERLRGETLNFDLADGDKVIVEAGKRITARHVKQLEAAGVAALAVPDDYLVG
CCCEEEEECHHHCCCEEEEECCCCCEEEECCCCHHHHHHHHHHHHCCEEEEECCCHHHHH
RILSHDVVDGSTGELLANANDEISEDQLTAFRKAGVDAVGTLWVNDLDRGPYLSNTLRID
HHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCEEEHEECCCCCCCCCCCCEEEC
PTKTQLEALVEIYRMMRPGEPPTKEAAQNLFHNLFFTFERYDLSTVGRMKFNRRVGRKDV
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHH
LGESVLYDKKYFAERNDEESKRLVAEHTDTSDILEVIKVLTEIRNGRGVVDDIDHLGNRR
CCCHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHH
VRSVGEMAENVFRVGLVRVERAVKERLSMAESEGLTPQELINAKPVAAAIKEFFGSSQLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHCHHHHH
QFMDQNNPLSEVTHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRVCTIETPEGPNIGLI
HHHHCCCCHHHHHHHHHHHCCCCCCCCHHHCCCEEEECCCCCCCCEEEEECCCCCCCCHH
NSLAVFARTNQYGFLETPYRKVLDGKVSDDVEYLSAIEENEYVIAQANALTDAKNMLTEQ
HHHEEEEECCCCCCCCCCHHHHHCCCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHH
FVPCRFQGESLLKPPSEVHFMDVSPMQTVSVAAALVPFLEHDDANRALMGANMQRQAVPT
CCCCEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCEECCCCCHHHHCCH
LRSQKPLVGTGIERAVARDSGVTVNALRGGVIEQIDAARIVVKVNEAEIGGGTDAGVDIY
HHCCCCCCCCCHHHHHHCCCCCEEEHHCCCHHHHHCCEEEEEEEECCCCCCCCCCCHHHH
NLIKYTRSNQNTCINQRPLVNVGDVIARGDVLADGPSTDIGELALGQNMLIAFMPWNGYN
HHHHHHCCCCCCCCCCCCCCCHHHHHHCCCEECCCCCCCHHHHHCCCCEEEEEECCCCCC
FEDSILLSERVVEEDRYTTIHIEELTCVARDTKLGPEEISADIPNVSEQALNRLDESGVV
CCCHHHHHHHHHHCCCEEEEEEEHEEEEHHCCCCCHHHHCCCCCCHHHHHHHHCCCCCEE
YIGAEVRAGDIMVGKVTPKGESQLTPEEKLLRAIFGEKASDVKDSSLRVPPGMDGTVIDV
EEECEEEECCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEECCCCCCCCEEEE
QVFTRDGIEKDKRARQIEENEIKRVKKDFDDQFRILEAAIYARLRSQIVGKVANGGANLK
EEEECCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
KGDSVTDAYLDGLKKSDWFQLRMKDEDAADAIERAQKQIQAHEKEFEARFADKRGKITQG
CCCCHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DDLAPGVLKMVKVFLAVKRRIQPGDKMAGRHGNKGVVSNVVPVEDMPYMATGESVDIVLN
CCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCEECCCCEEEEEE
PLGVPSRMNIGQILEVHLGWAAKGLGRKIQRMLEAQAAVSELRKFLDDIYNHDNAINAQR
CCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
VDLSQFSDEELLNLGKNLIDGVPMATPVFDGASEAEIKRMLELADLPQSGQTQLYDGRTG
CCHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEECCCCC
EAFDRKTTVGYMHYLKLNHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWAL
CCCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEE
EAYGAAYTLQEMLTVKSDDVQGRNQMYKNIVDGEHEMVAGMPESFNVLVKEIRSLAIHME
EHHCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHEEEEE
LEE
ECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA