Click here to switch to the map view.

The map label for this gene is cheA [H]

Identifier: 84624350

GI number: 84624350

Start: 3026169

End: 3028178

Strand: Direct

Name: cheA [H]

Synonym: XOO_2693

Alternate gene names: 84624350

Gene position: 3026169-3028178 (Clockwise)

Preceding gene: 84624349

Following gene: 84624351

Centisome position: 61.26

GC content: 65.47

Gene sequence:

>2010_bases
ATGAGCATGGACCTGCAACGTTTCCACGCCACCTTTTTCGAAGAGAGCCGCGAAGGACTCGACGCGATGGAGGCCGGGCT
GTTGTCGCTTGAAGAGGGCAACCGCGACCCGGAAATCATCAACTCGGTGTTCCGTGCCGCGCACTCGATCAAGGGCGGTG
CTGCCACTTTCGGTTTCGATGCCATCGCCGGCCTGACCCACGTGCTGGAAACGCTGCTGGATGAGTTGCGCTCCAACAAG
CGCCAGCTCGAACCCAATGCGGTCGATGCCATGCTTGGCTCGGTCGACGTGCTGCGCGCGCTATTGCGCGAAGCCGAACA
CGGCACCCCGGCCGACCCGACCGCGGTCAAGGCCGTGCATACCCGTTTGAACGCTGTGCTCGCCGGCGAAGCGCCGGCGG
CTGCGGTGGTCGCCAAGCCGAAGGAAGAAGAGCCCGAAGCCTGGCACATCGGCTTCACTCCCGCGCCGTCGCTGTTCATG
AGCGGCAACGACCCGCTGCGCATCATCCGCGAGCTGGAGCATCTGGGCCCGCTGCAGATCGCCGCGCGCCTGGAACGTAT
GCCCGGCTTCGAGAACATCGACCCGCTGGAAGCGTATCTGGCGTGGGACCTGGGCTTGATCGGCAAGATTCCCCGCAACA
AGATCGAAGACACCTTTGCCTGGGTAGTGGACGACTGCGAACTGGACATCCGCCCGATGGCGGTGCCCGGCCCGCCGCCG
AGCCTGGCGGTGGACGCTCCGGCGGCCGCACCGGGCGCCGCCGTCACCGCGGCACCGAGTGCCGCTGCCGAACCTGCTGC
CGCTGCAGCAACGCCGGCCAAGGCCGCCGCTGCCGAAGCCGAAAGCTCGATCCGCGTCAGCGTCGACAAGGTCGATGCCT
TGATCAACCTGGTCGGTGAGTTGGTGATTACCCAGGCCATGCTCAAGCAGGTGTCCGCCGGGCTGGACCCGGCGCATGCC
GAACAGCTGTTCGCTGGTCTGGATCTGCTCGAGCGCAATACCCGCGATCTGCAGGAAGCGGTCATCGGTGTGCGCATGCT
GCCCGTCGATGCGGTGTTCCGCCGCTTCCCGCGTCTGGTGCGCGACCTCTCCAGCCGTCTCGGCAAGCAAGTGCGCTTGC
GCACCATTGGCGAGAGCACCGAGTTGGACAAGGGGCTGATTGAAAAGATTGCCGATCCGCTGGTGCACCTGGTGCGCAAC
TCGATCGACCATGGTCTGGAAATGCCCGACGCGCGCCGCGCCTCCGGCAAGGACGAGACCGGCACCATCACCCTGGCGGC
ATCGCATCAGGGCGGTCACATCGTGATCGAAGTCAGCGACGACGGCCGTGGCCTCAATCGCGCCAAGATTCTGGAAAAAG
CGGCCGAACGCGGCATTGCCGTACCGGACAACCCGACCGATGCGCAGGTGTGGGATTTGATCTTCGCACCGGGCTTCTCC
ACCGCCGATGCCGTCACCGACCTGTCCGGTCGTGGCGTGGGCATGGACGTGGTGCGCCGTAACATCCAGGGCCTGGGTGG
CGAAGTGCAGCTGGAAAGCAACGCCGGCAGCGGGACCCGCGTGCTGATCCGTCTGCCGCTGACCCTGGCCATCCTCGACG
GCATGACCGTGTCGGTCGCCGGCGAGACCCTGATCCTGCCGCTATCCTACGTGCTCGAAGCACTGCAGCCGGCGGCGGAA
GACATCCGCTCGATGGCCGGCGACGGCCGGGTACTACGGGTGCGTGGCGAGTATCTGCCGATCCTGTCGCTCACCAATTA
CTACGGCTTCGGCGGGCAGCAGTCCTCCCAGGAATCGCTGGTGGTGGTGGTCGAAGGCGACGGCCAGAAGATCGCACTGG
AAGTGGACGAATTGCTTGGCCAGCAGCAGGTCGTGGTCAAGAACATCGAGAACAATTACCGGCGGATTCCGGGCGTCTCC
GGCGCCACCATCCTCGGCGATGGGCGGGTTTCGCTGATCGTGGATATCGGTGGTCTGGTGCGCTCGCTGAAGGTACCGCA
GGCCGCGTAA

Upstream 100 bases:

>100_bases
GGGTTGGCTGGTCAAGCCGTTCAATCCAGAACAGCTCATCGCCACCGTGCAGAAAGTTCTCGGTTAAACCCTTTTCGCTT
CACCTTCGGATTTCACGCCC

Downstream 100 bases:

>100_bases
TGCAAATGCAGTCGCCGCGGCATGGAAGCCGCGGCGCGAGGCTCCAGCAGGGGTTCAGCCGACATACGTGTAAAAATAGC
TCACAAGATCGGATTTCATC

Product: chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 669; Mature: 668

Protein sequence:

>669_residues
MSMDLQRFHATFFEESREGLDAMEAGLLSLEEGNRDPEIINSVFRAAHSIKGGAATFGFDAIAGLTHVLETLLDELRSNK
RQLEPNAVDAMLGSVDVLRALLREAEHGTPADPTAVKAVHTRLNAVLAGEAPAAAVVAKPKEEEPEAWHIGFTPAPSLFM
SGNDPLRIIRELEHLGPLQIAARLERMPGFENIDPLEAYLAWDLGLIGKIPRNKIEDTFAWVVDDCELDIRPMAVPGPPP
SLAVDAPAAAPGAAVTAAPSAAAEPAAAAATPAKAAAAEAESSIRVSVDKVDALINLVGELVITQAMLKQVSAGLDPAHA
EQLFAGLDLLERNTRDLQEAVIGVRMLPVDAVFRRFPRLVRDLSSRLGKQVRLRTIGESTELDKGLIEKIADPLVHLVRN
SIDHGLEMPDARRASGKDETGTITLAASHQGGHIVIEVSDDGRGLNRAKILEKAAERGIAVPDNPTDAQVWDLIFAPGFS
TADAVTDLSGRGVGMDVVRRNIQGLGGEVQLESNAGSGTRVLIRLPLTLAILDGMTVSVAGETLILPLSYVLEALQPAAE
DIRSMAGDGRVLRVRGEYLPILSLTNYYGFGGQQSSQESLVVVVEGDGQKIALEVDELLGQQQVVVKNIENNYRRIPGVS
GATILGDGRVSLIVDIGGLVRSLKVPQAA

Sequences:

>Translated_669_residues
MSMDLQRFHATFFEESREGLDAMEAGLLSLEEGNRDPEIINSVFRAAHSIKGGAATFGFDAIAGLTHVLETLLDELRSNK
RQLEPNAVDAMLGSVDVLRALLREAEHGTPADPTAVKAVHTRLNAVLAGEAPAAAVVAKPKEEEPEAWHIGFTPAPSLFM
SGNDPLRIIRELEHLGPLQIAARLERMPGFENIDPLEAYLAWDLGLIGKIPRNKIEDTFAWVVDDCELDIRPMAVPGPPP
SLAVDAPAAAPGAAVTAAPSAAAEPAAAAATPAKAAAAEAESSIRVSVDKVDALINLVGELVITQAMLKQVSAGLDPAHA
EQLFAGLDLLERNTRDLQEAVIGVRMLPVDAVFRRFPRLVRDLSSRLGKQVRLRTIGESTELDKGLIEKIADPLVHLVRN
SIDHGLEMPDARRASGKDETGTITLAASHQGGHIVIEVSDDGRGLNRAKILEKAAERGIAVPDNPTDAQVWDLIFAPGFS
TADAVTDLSGRGVGMDVVRRNIQGLGGEVQLESNAGSGTRVLIRLPLTLAILDGMTVSVAGETLILPLSYVLEALQPAAE
DIRSMAGDGRVLRVRGEYLPILSLTNYYGFGGQQSSQESLVVVVEGDGQKIALEVDELLGQQQVVVKNIENNYRRIPGVS
GATILGDGRVSLIVDIGGLVRSLKVPQAA
>Mature_668_residues
SMDLQRFHATFFEESREGLDAMEAGLLSLEEGNRDPEIINSVFRAAHSIKGGAATFGFDAIAGLTHVLETLLDELRSNKR
QLEPNAVDAMLGSVDVLRALLREAEHGTPADPTAVKAVHTRLNAVLAGEAPAAAVVAKPKEEEPEAWHIGFTPAPSLFMS
GNDPLRIIRELEHLGPLQIAARLERMPGFENIDPLEAYLAWDLGLIGKIPRNKIEDTFAWVVDDCELDIRPMAVPGPPPS
LAVDAPAAAPGAAVTAAPSAAAEPAAAAATPAKAAAAEAESSIRVSVDKVDALINLVGELVITQAMLKQVSAGLDPAHAE
QLFAGLDLLERNTRDLQEAVIGVRMLPVDAVFRRFPRLVRDLSSRLGKQVRLRTIGESTELDKGLIEKIADPLVHLVRNS
IDHGLEMPDARRASGKDETGTITLAASHQGGHIVIEVSDDGRGLNRAKILEKAAERGIAVPDNPTDAQVWDLIFAPGFST
ADAVTDLSGRGVGMDVVRRNIQGLGGEVQLESNAGSGTRVLIRLPLTLAILDGMTVSVAGETLILPLSYVLEALQPAAED
IRSMAGDGRVLRVRGEYLPILSLTNYYGFGGQQSSQESLVVVVEGDGQKIALEVDELLGQQQVVVKNIENNYRRIPGVSG
ATILGDGRVSLIVDIGGLVRSLKVPQAA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=672, Percent_Identity=45.8333333333333, Blast_Score=542, Evalue=1e-155,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR015162
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF09078 CheY-binding; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 71203; Mature: 71072

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMDLQRFHATFFEESREGLDAMEAGLLSLEEGNRDPEIINSVFRAAHSIKGGAATFGFD
CCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHH
AIAGLTHVLETLLDELRSNKRQLEPNAVDAMLGSVDVLRALLREAEHGTPADPTAVKAVH
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHH
TRLNAVLAGEAPAAAVVAKPKEEEPEAWHIGFTPAPSLFMSGNDPLRIIRELEHLGPLQI
HHHHHHEECCCCCEEEEECCCCCCCCEEEECCCCCCCEEECCCCHHHHHHHHHHCCHHHH
AARLERMPGFENIDPLEAYLAWDLGLIGKIPRNKIEDTFAWVVDDCELDIRPMAVPGPPP
HHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHEEEECCCCCEEEEECCCCCC
SLAVDAPAAAPGAAVTAAPSAAAEPAAAAATPAKAAAAEAESSIRVSVDKVDALINLVGE
CCEECCCCCCCCCCEECCCCCCCCCCHHHCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHH
LVITQAMLKQVSAGLDPAHAEQLFAGLDLLERNTRDLQEAVIGVRMLPVDAVFRRFPRLV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHH
RDLSSRLGKQVRLRTIGESTELDKGLIEKIADPLVHLVRNSIDHGLEMPDARRASGKDET
HHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GTITLAASHQGGHIVIEVSDDGRGLNRAKILEKAAERGIAVPDNPTDAQVWDLIFAPGFS
CEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHEEECCCCC
TADAVTDLSGRGVGMDVVRRNIQGLGGEVQLESNAGSGTRVLIRLPLTLAILDGMTVSVA
CHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCHHHHHHCCCEEEEC
GETLILPLSYVLEALQPAAEDIRSMAGDGRVLRVRGEYLPILSLTNYYGFGGQQSSQESL
CCEEEEEHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEECEEEECCCCCCCCCCCCCCCE
VVVVEGDGQKIALEVDELLGQQQVVVKNIENNYRRIPGVSGATILGDGRVSLIVDIGGLV
EEEEECCCCEEEEEHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEEHHHHH
RSLKVPQAA
HHCCCCCCC
>Mature Secondary Structure 
SMDLQRFHATFFEESREGLDAMEAGLLSLEEGNRDPEIINSVFRAAHSIKGGAATFGFD
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHH
AIAGLTHVLETLLDELRSNKRQLEPNAVDAMLGSVDVLRALLREAEHGTPADPTAVKAVH
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHH
TRLNAVLAGEAPAAAVVAKPKEEEPEAWHIGFTPAPSLFMSGNDPLRIIRELEHLGPLQI
HHHHHHEECCCCCEEEEECCCCCCCCEEEECCCCCCCEEECCCCHHHHHHHHHHCCHHHH
AARLERMPGFENIDPLEAYLAWDLGLIGKIPRNKIEDTFAWVVDDCELDIRPMAVPGPPP
HHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHEEEECCCCCEEEEECCCCCC
SLAVDAPAAAPGAAVTAAPSAAAEPAAAAATPAKAAAAEAESSIRVSVDKVDALINLVGE
CCEECCCCCCCCCCEECCCCCCCCCCHHHCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHH
LVITQAMLKQVSAGLDPAHAEQLFAGLDLLERNTRDLQEAVIGVRMLPVDAVFRRFPRLV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHH
RDLSSRLGKQVRLRTIGESTELDKGLIEKIADPLVHLVRNSIDHGLEMPDARRASGKDET
HHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GTITLAASHQGGHIVIEVSDDGRGLNRAKILEKAAERGIAVPDNPTDAQVWDLIFAPGFS
CEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHEEECCCCC
TADAVTDLSGRGVGMDVVRRNIQGLGGEVQLESNAGSGTRVLIRLPLTLAILDGMTVSVA
CHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCHHHHHHCCCEEEEC
GETLILPLSYVLEALQPAAEDIRSMAGDGRVLRVRGEYLPILSLTNYYGFGGQQSSQESL
CCEEEEEHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEECEEEECCCCCCCCCCCCCCCE
VVVVEGDGQKIALEVDELLGQQQVVVKNIENNYRRIPGVSGATILGDGRVSLIVDIGGLV
EEEEECCCCEEEEEHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEEHHHHH
RSLKVPQAA
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2002011; 9097040; 9278503; 3510184; 2832069; 2068106; 8555213; 8639521; 9020767; 9437425; 9636149 [H]