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The map label for this gene is corC [H]

Identifier: 84624268

GI number: 84624268

Start: 2911516

End: 2912394

Strand: Direct

Name: corC [H]

Synonym: XOO_2611

Alternate gene names: 84624268

Gene position: 2911516-2912394 (Clockwise)

Preceding gene: 84624267

Following gene: 84624269

Centisome position: 58.93

GC content: 63.03

Gene sequence:

>879_bases
ATGTCCGAAGACGACAGTAGCCAATCCCTAGAAGCACCGGAAAAACGCCGTAGCTGGCTCGAGCGCCTCAGCGCTGCCTT
CTCTGGCGAACCCCATACCCGCGACGAACTTGTCGCCTTGCTGCGGACCGCCGAACAGGACGGGCTCATCGCCGCAGACA
CCTTGCGCATGATGGAAGGCGCGATTTCCGTGTCCGAGCTCACCGTGGGCGATGTGATGATCTCGCGCTCGCAGATGGTC
TCGCTGCCAGTGGAAGCGCGTTTCATCGACCTGATGAAGCAGGTGGTCGAATCCGGCCATTCGCGCTTTCCGGTGCACGG
CGAGAACAAGGACGAAGTGCTCGGCATCTTGCTGGCCAAGGACTTGCTGCGCGGCGTCGTTGCCGATAACGGACCTGGCA
ACGTGCGCGAATTGCTGCGCCCGGCGGTGCTGATCCCAGAGTCCAAGAAGCTCAATGTCCTGCTCAAGGAATTCCGCCTG
TCGCGCAACCACATGGCGATCGTGGTGGACGAGTACGGCGGTGTTGCCGGGCTGGTCACCATCGAGGACGTGCTGGAACA
GATCGTCGGCGAGATCGACGACGAGCACGACGATGCCGAGGACGAGAATTCGCTCATTGCGATCCAGGCCGACGGACGCT
ATGTGGTCGATGCGTTGACGCCGATCGAAGACTTCAACGAACGCTTCGGCGCCGAGTTCCCCGACGACGAGTACGACACT
GTCGGCGGGCTGGTCACCGATGCGATCGGGCACCTGCCCGAAACCGGCGAAGAGCTGACGCTCGGGCGGTTTGCGTTCCG
CGTGGCCAAGGCCGATGCGCGGCGCGTGCATGCCTTCCACGTCACCATTCTGCCGCCCGACCCGCAGGACGACGCTTGA

Upstream 100 bases:

>100_bases
CCTTGAGCAGACCAGGTAACAGCGCATCCACAGCGCCGTGCCGGCTTCCTGCTAGACTGATGGCTAACGCCTGGTTTGCC
GGGTGCCCTTCCCCGTCACG

Downstream 100 bases:

>100_bases
ACCTGTCGCATGGCATGACCGCTGCAGCGCAGGTGAGCTGCAGCGCCCGGCGTCGGGCTGCATGCTGGCTGTTCGCATTG
CTGGCACTGTTGGTGACGCC

Product: polar amino acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSEDDSSQSLEAPEKRRSWLERLSAAFSGEPHTRDELVALLRTAEQDGLIAADTLRMMEGAISVSELTVGDVMISRSQMV
SLPVEARFIDLMKQVVESGHSRFPVHGENKDEVLGILLAKDLLRGVVADNGPGNVRELLRPAVLIPESKKLNVLLKEFRL
SRNHMAIVVDEYGGVAGLVTIEDVLEQIVGEIDDEHDDAEDENSLIAIQADGRYVVDALTPIEDFNERFGAEFPDDEYDT
VGGLVTDAIGHLPETGEELTLGRFAFRVAKADARRVHAFHVTILPPDPQDDA

Sequences:

>Translated_292_residues
MSEDDSSQSLEAPEKRRSWLERLSAAFSGEPHTRDELVALLRTAEQDGLIAADTLRMMEGAISVSELTVGDVMISRSQMV
SLPVEARFIDLMKQVVESGHSRFPVHGENKDEVLGILLAKDLLRGVVADNGPGNVRELLRPAVLIPESKKLNVLLKEFRL
SRNHMAIVVDEYGGVAGLVTIEDVLEQIVGEIDDEHDDAEDENSLIAIQADGRYVVDALTPIEDFNERFGAEFPDDEYDT
VGGLVTDAIGHLPETGEELTLGRFAFRVAKADARRVHAFHVTILPPDPQDDA
>Mature_291_residues
SEDDSSQSLEAPEKRRSWLERLSAAFSGEPHTRDELVALLRTAEQDGLIAADTLRMMEGAISVSELTVGDVMISRSQMVS
LPVEARFIDLMKQVVESGHSRFPVHGENKDEVLGILLAKDLLRGVVADNGPGNVRELLRPAVLIPESKKLNVLLKEFRLS
RNHMAIVVDEYGGVAGLVTIEDVLEQIVGEIDDEHDDAEDENSLIAIQADGRYVVDALTPIEDFNERFGAEFPDDEYDTV
GGLVTDAIGHLPETGEELTLGRFAFRVAKADARRVHAFHVTILPPDPQDDA

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=208, Percent_Identity=31.7307692307692, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI94681046, Length=185, Percent_Identity=30.2702702702703, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI40068055, Length=188, Percent_Identity=28.7234042553192, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI40068053, Length=188, Percent_Identity=28.7234042553192, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1786879, Length=289, Percent_Identity=46.7128027681661, Blast_Score=237, Evalue=7e-64,
Organism=Escherichia coli, GI87082033, Length=236, Percent_Identity=29.6610169491525, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI145693175, Length=211, Percent_Identity=25.5924170616114, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1790664, Length=257, Percent_Identity=25.2918287937743, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1788119, Length=233, Percent_Identity=30.9012875536481, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 32117; Mature: 31986

Theoretical pI: Translated: 4.22; Mature: 4.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEDDSSQSLEAPEKRRSWLERLSAAFSGEPHTRDELVALLRTAEQDGLIAADTLRMMEG
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEHHHHHHHHHH
AISVSELTVGDVMISRSQMVSLPVEARFIDLMKQVVESGHSRFPVHGENKDEVLGILLAK
HCCHHHEEHHHHHHCCHHHEECCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
DLLRGVVADNGPGNVRELLRPAVLIPESKKLNVLLKEFRLSRNHMAIVVDEYGGVAGLVT
HHHHHHHCCCCCCHHHHHHCCCEECCCCCHHHHHHHHHHCCCCCEEEEEECCCCEEEEHH
IEDVLEQIVGEIDDEHDDAEDENSLIAIQADGRYVVDALTPIEDFNERFGAEFPDDEYDT
HHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEEEEHHCCHHHHHHHHCCCCCCCCHHH
VGGLVTDAIGHLPETGEELTLGRFAFRVAKADARRVHAFHVTILPPDPQDDA
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCCCC
>Mature Secondary Structure 
SEDDSSQSLEAPEKRRSWLERLSAAFSGEPHTRDELVALLRTAEQDGLIAADTLRMMEG
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEHHHHHHHHHH
AISVSELTVGDVMISRSQMVSLPVEARFIDLMKQVVESGHSRFPVHGENKDEVLGILLAK
HCCHHHEEHHHHHHCCHHHEECCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
DLLRGVVADNGPGNVRELLRPAVLIPESKKLNVLLKEFRLSRNHMAIVVDEYGGVAGLVT
HHHHHHHCCCCCCHHHHHHCCCEECCCCCHHHHHHHHHHCCCCCEEEEEECCCCEEEEHH
IEDVLEQIVGEIDDEHDDAEDENSLIAIQADGRYVVDALTPIEDFNERFGAEFPDDEYDT
HHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEEEEHHCCHHHHHHHHCCCCCCCCHHH
VGGLVTDAIGHLPETGEELTLGRFAFRVAKADARRVHAFHVTILPPDPQDDA
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]