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The map label for this gene is 84624250

Identifier: 84624250

GI number: 84624250

Start: 2893450

End: 2894007

Strand: Direct

Name: 84624250

Synonym: XOO_2593

Alternate gene names: NA

Gene position: 2893450-2894007 (Clockwise)

Preceding gene: 84624249

Following gene: 84624253

Centisome position: 58.57

GC content: 66.13

Gene sequence:

>558_bases
TTGCGCAACAAGGTGCTGGTCAGTGCTGACGGACGCCGTGGGCGGATCACCGAAGTGGAAGCCTATTGCGGCAGCGAAGA
CCCGGCCGCGCACTCGTTCCGCGGCATGCCCCCGCGAACGCGGATGATGTGCGGTCCGCCTGGGCAGCTGTATGCGTATT
TCATCTATGGCATGCACCGGGCGATCAATGCCGTGTGCGGCGGTGCGCCCGGGCATGCAGTACTCATCCGCGCACTGGAA
CCTTTCGACGGTCTCGACAGCATGCAGGCCGCACGCGGTGCGGCGCCGGCCAAACTGCTGACCATCGGTCCAGGACGCCT
GGCACAAGCGTTTGGCGTGACCGCTGCCGACAACGGGTTGGATCTCACAACGGGCGCTGCGCGGCTCTGGATCGAAGACG
ACGGTGTGCCGCCACCCGCCAACCCACCGGCGACAGCACGCATCGGCATCCGTAACGCGGTGGATACGCCATGGCGCTGG
TTGGTTGCCGACAGCCGCTATGTGTCGCGTCAGCTTCGGCGCATGGATGGTACAGGCACTGGGCTGCCGGGCGACTGA

Upstream 100 bases:

>100_bases
GGCTGCAACGTGACGCACACGCAGCTAGGCTTTGCGCATGACATCAAAGCCCCTGCCCCGCTCGTTTTAAGCGCACGATG
CGCGCCACGTCGCGCCGCAA

Downstream 100 bases:

>100_bases
GCCAGCCAGCGTTCCATCGGCGATTGCCCCAGGCCGCACCCGGCCCACGCTGCAGCCGTCGTAGTGCCTGCTCAGCCTGC
TCGGGGGTGAGTTCCTGCAC

Product: 3-methyladenine DNA glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MRNKVLVSADGRRGRITEVEAYCGSEDPAAHSFRGMPPRTRMMCGPPGQLYAYFIYGMHRAINAVCGGAPGHAVLIRALE
PFDGLDSMQAARGAAPAKLLTIGPGRLAQAFGVTAADNGLDLTTGAARLWIEDDGVPPPANPPATARIGIRNAVDTPWRW
LVADSRYVSRQLRRMDGTGTGLPGD

Sequences:

>Translated_185_residues
MRNKVLVSADGRRGRITEVEAYCGSEDPAAHSFRGMPPRTRMMCGPPGQLYAYFIYGMHRAINAVCGGAPGHAVLIRALE
PFDGLDSMQAARGAAPAKLLTIGPGRLAQAFGVTAADNGLDLTTGAARLWIEDDGVPPPANPPATARIGIRNAVDTPWRW
LVADSRYVSRQLRRMDGTGTGLPGD
>Mature_185_residues
MRNKVLVSADGRRGRITEVEAYCGSEDPAAHSFRGMPPRTRMMCGPPGQLYAYFIYGMHRAINAVCGGAPGHAVLIRALE
PFDGLDSMQAARGAAPAKLLTIGPGRLAQAFGVTAADNGLDLTTGAARLWIEDDGVPPPANPPATARIGIRNAVDTPWRW
LVADSRYVSRQLRRMDGTGTGLPGD

Specific function: Unknown

COG id: COG2094

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA glycosylase MPG family [H]

Homologues:

Organism=Homo sapiens, GI62632769, Length=136, Percent_Identity=42.6470588235294, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI62632771, Length=136, Percent_Identity=42.6470588235294, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI62632765, Length=136, Percent_Identity=42.6470588235294, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011034
- InterPro:   IPR003180 [H]

Pfam domain/function: PF02245 Pur_DNA_glyco [H]

EC number: NA

Molecular weight: Translated: 19683; Mature: 19683

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNKVLVSADGRRGRITEVEAYCGSEDPAAHSFRGMPPRTRMMCGPPGQLYAYFIYGMHR
CCCCEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHH
AINAVCGGAPGHAVLIRALEPFDGLDSMQAARGAAPAKLLTIGPGRLAQAFGVTAADNGL
HHHHHHCCCCCCEEEEEECCCCCCCHHHHHHCCCCCEEEEEECCCHHHHHHCCEECCCCC
DLTTGAARLWIEDDGVPPPANPPATARIGIRNAVDTPWRWLVADSRYVSRQLRRMDGTGT
EECCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCHHHHHHHHHCCCCCC
GLPGD
CCCCC
>Mature Secondary Structure
MRNKVLVSADGRRGRITEVEAYCGSEDPAAHSFRGMPPRTRMMCGPPGQLYAYFIYGMHR
CCCCEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHH
AINAVCGGAPGHAVLIRALEPFDGLDSMQAARGAAPAKLLTIGPGRLAQAFGVTAADNGL
HHHHHHCCCCCCEEEEEECCCCCCCHHHHHHCCCCCEEEEEECCCHHHHHHCCEECCCCC
DLTTGAARLWIEDDGVPPPANPPATARIGIRNAVDTPWRWLVADSRYVSRQLRRMDGTGT
EECCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCHHHHHHHHHCCCCCC
GLPGD
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]