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The map label for this gene is cysS [H]

Identifier: 84624181

GI number: 84624181

Start: 2817069

End: 2818499

Strand: Direct

Name: cysS [H]

Synonym: XOO_2524

Alternate gene names: 84624181

Gene position: 2817069-2818499 (Clockwise)

Preceding gene: 84624166

Following gene: 84624182

Centisome position: 57.02

GC content: 65.34

Gene sequence:

>1431_bases
ATGCCGATGAGCCTGCGCCTGCACAACAACCTTACGCGGCGGGTCGAACCGTTCACGCCGCTCGATCCGTCCAGCCCCAC
CCTCTATGTCTGCGGCCCTACCGTTTACAACTATGCGCATATCGGCAACGCCCGCGGCCCGGTGGTGTTCGATGTCCTGG
CCGCGCTGTTGCGCCGACGCTACGGCGCGCTGCGCTACGCGCGCAACATCACCGACGTGGACGACAAGATCAACGCTGCA
GCGCAGGCGCAGGGCGTCCCGATCTCGACGATCACCGACCGCTTCGCCGCGATCTACCGGCAGGACATGGCCGCGCTCGG
TGTGGTGCCGCCGGATATCGAACCGGAAGCCACCGCGCATATTCCGCAGATCGTGGCGATGATCGAGCAGTTGATCGCCA
ATGGGCACGCCTACGCCGCCGAAGGCCACGTGCTGTTTTCGGTGTCCAGCTTCGAGGACTACGGCAAACTCTCGCGGCGC
GATCCGGATGAAATGCTGGCCGGCGCGCGCGTGGACGTGGCGCCGTACAAGCGCGACCCTGGCGACTTCGTGCTGTGGAA
ACCCTCCAGCGACGAGCTTCCCGGCTGGGAATCGCCCTGGGGCCGTGGCCGCCCGGGCTGGCATATCGAGTGCTCGGCGA
TGGCCGCCGCACATCTGGGGCCGACCATCGACATCCACGCCGGCGGCGTTGACCTGCAGTTCCCGCATCACGAAAACGAA
ATTGCGCAGAGCGAATGCGCGCATGGCGGCGCCACCTTTGCGCGGTTCTGGCTGCACAACGGCATGCTCAATTTCAGCGG
CGCGAAGATGAGCAAGTCGCTGGGCAACATCGAAACCGTGCACGACCTGATTGCCAAGCATCCGCCCGAAGCGCTGCGCT
ACGCGCTGCTGAGCGCGCACTACCGTCAGCCGCTGGACTGGTCGGATGGTTTGATCGAGCAGGCCACGAACACGCTGGAC
CGGTTGTATGGAACGCTGCGGGATCTGGCTGCGTTGGAAGCCTGCGGAAGCAGTGGCGTCGAAGTATCGAAGACGATCCC
CGTCGAAGTGGAGTCTGCTCTCCAAGACGATCTCAACACGCCGCTGGCCTTGTCGGTTATCGCCAGCATCGCCTCGGAAG
CGCGTGCGTTGCGCAACGAGTTGGTTCATGGCGGCGAACCTTCGGCACGTATGAGCGAGCTCCATGCGGTGCGCGCAAAG
TTGCTGGGTGCCGGCCTGGCCCTGGGGCTGCTTCAACAGGACCCGGCCGCATGGTTCTCGCGCGGCACCGACGCCGACGA
CGATGCGCGCATCACTGCGCTGGTCCAAGAGCGCAGCGCCGCGAAGAAGGCCAAGGATTTCGCCCGGGCCGACGCCATCC
GCAAGCAGCTCGCCGACGAAGGTATCGTGCTGGAAGACACACCGCAGGGCGTGCGCTGGAAACGCGCCTGA

Upstream 100 bases:

>100_bases
GCGAGCCTGTGCTGAACGCAGCCCATCCGGTCGCTGTTGTCCACAGCCGATTCGTCATCCCGCCGCAACGAGCTAGAATC
GCGCGATTGCCCTTCTTCGG

Downstream 100 bases:

>100_bases
CCGTTCCTTCTTCCACCGGGAGAGGGGCGCGCGCAGGGCCGGATGAGGGTGCGAGCTAGGCCGTGTTCATCGATCTCAGC
AGGCTTCGCACTTACCCTCA

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MPMSLRLHNNLTRRVEPFTPLDPSSPTLYVCGPTVYNYAHIGNARGPVVFDVLAALLRRRYGALRYARNITDVDDKINAA
AQAQGVPISTITDRFAAIYRQDMAALGVVPPDIEPEATAHIPQIVAMIEQLIANGHAYAAEGHVLFSVSSFEDYGKLSRR
DPDEMLAGARVDVAPYKRDPGDFVLWKPSSDELPGWESPWGRGRPGWHIECSAMAAAHLGPTIDIHAGGVDLQFPHHENE
IAQSECAHGGATFARFWLHNGMLNFSGAKMSKSLGNIETVHDLIAKHPPEALRYALLSAHYRQPLDWSDGLIEQATNTLD
RLYGTLRDLAALEACGSSGVEVSKTIPVEVESALQDDLNTPLALSVIASIASEARALRNELVHGGEPSARMSELHAVRAK
LLGAGLALGLLQQDPAAWFSRGTDADDDARITALVQERSAAKKAKDFARADAIRKQLADEGIVLEDTPQGVRWKRA

Sequences:

>Translated_476_residues
MPMSLRLHNNLTRRVEPFTPLDPSSPTLYVCGPTVYNYAHIGNARGPVVFDVLAALLRRRYGALRYARNITDVDDKINAA
AQAQGVPISTITDRFAAIYRQDMAALGVVPPDIEPEATAHIPQIVAMIEQLIANGHAYAAEGHVLFSVSSFEDYGKLSRR
DPDEMLAGARVDVAPYKRDPGDFVLWKPSSDELPGWESPWGRGRPGWHIECSAMAAAHLGPTIDIHAGGVDLQFPHHENE
IAQSECAHGGATFARFWLHNGMLNFSGAKMSKSLGNIETVHDLIAKHPPEALRYALLSAHYRQPLDWSDGLIEQATNTLD
RLYGTLRDLAALEACGSSGVEVSKTIPVEVESALQDDLNTPLALSVIASIASEARALRNELVHGGEPSARMSELHAVRAK
LLGAGLALGLLQQDPAAWFSRGTDADDDARITALVQERSAAKKAKDFARADAIRKQLADEGIVLEDTPQGVRWKRA
>Mature_475_residues
PMSLRLHNNLTRRVEPFTPLDPSSPTLYVCGPTVYNYAHIGNARGPVVFDVLAALLRRRYGALRYARNITDVDDKINAAA
QAQGVPISTITDRFAAIYRQDMAALGVVPPDIEPEATAHIPQIVAMIEQLIANGHAYAAEGHVLFSVSSFEDYGKLSRRD
PDEMLAGARVDVAPYKRDPGDFVLWKPSSDELPGWESPWGRGRPGWHIECSAMAAAHLGPTIDIHAGGVDLQFPHHENEI
AQSECAHGGATFARFWLHNGMLNFSGAKMSKSLGNIETVHDLIAKHPPEALRYALLSAHYRQPLDWSDGLIEQATNTLDR
LYGTLRDLAALEACGSSGVEVSKTIPVEVESALQDDLNTPLALSVIASIASEARALRNELVHGGEPSARMSELHAVRAKL
LGAGLALGLLQQDPAAWFSRGTDADDDARITALVQERSAAKKAKDFARADAIRKQLADEGIVLEDTPQGVRWKRA

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=380, Percent_Identity=40, Blast_Score=255, Evalue=5e-68,
Organism=Homo sapiens, GI10835051, Length=303, Percent_Identity=35.6435643564356, Blast_Score=205, Evalue=8e-53,
Organism=Homo sapiens, GI62240992, Length=303, Percent_Identity=35.6435643564356, Blast_Score=205, Evalue=9e-53,
Organism=Homo sapiens, GI21269877, Length=303, Percent_Identity=35.6435643564356, Blast_Score=205, Evalue=9e-53,
Organism=Homo sapiens, GI303304987, Length=303, Percent_Identity=35.6435643564356, Blast_Score=204, Evalue=1e-52,
Organism=Escherichia coli, GI1786737, Length=474, Percent_Identity=47.4683544303797, Blast_Score=398, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17509797, Length=249, Percent_Identity=39.3574297188755, Blast_Score=187, Evalue=8e-48,
Organism=Caenorhabditis elegans, GI17509795, Length=249, Percent_Identity=39.3574297188755, Blast_Score=187, Evalue=9e-48,
Organism=Saccharomyces cerevisiae, GI6324082, Length=307, Percent_Identity=35.5048859934853, Blast_Score=207, Evalue=2e-54,
Organism=Drosophila melanogaster, GI19922218, Length=500, Percent_Identity=34.6, Blast_Score=268, Evalue=9e-72,
Organism=Drosophila melanogaster, GI19922364, Length=303, Percent_Identity=37.953795379538, Blast_Score=213, Evalue=2e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 51783; Mature: 51652

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMSLRLHNNLTRRVEPFTPLDPSSPTLYVCGPTVYNYAHIGNARGPVVFDVLAALLRRR
CCCEEECCCCHHHHCCCCCCCCCCCCEEEEECCCHHHHHHCCCCCCCHHHHHHHHHHHHH
YGALRYARNITDVDDKINAAAQAQGVPISTITDRFAAIYRQDMAALGVVPPDIEPEATAH
HHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
IPQIVAMIEQLIANGHAYAAEGHVLFSVSSFEDYGKLSRRDPDEMLAGARVDVAPYKRDP
HHHHHHHHHHHHHCCCEEEECCEEEEEECCCHHHHHHCCCCHHHHHCCCCEEECCCCCCC
GDFVLWKPSSDELPGWESPWGRGRPGWHIECSAMAAAHLGPTIDIHAGGVDLQFPHHENE
CCEEEECCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCEEEEECCCEEEECCCCCHH
IAQSECAHGGATFARFWLHNGMLNFSGAKMSKSLGNIETVHDLIAKHPPEALRYALLSAH
HHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHH
YRQPLDWSDGLIEQATNTLDRLYGTLRDLAALEACGSSGVEVSKTIPVEVESALQDDLNT
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHCCC
PLALSVIASIASEARALRNELVHGGEPSARMSELHAVRAKLLGAGLALGLLQQDPAAWFS
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
RGTDADDDARITALVQERSAAKKAKDFARADAIRKQLADEGIVLEDTPQGVRWKRA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCC
>Mature Secondary Structure 
PMSLRLHNNLTRRVEPFTPLDPSSPTLYVCGPTVYNYAHIGNARGPVVFDVLAALLRRR
CCEEECCCCHHHHCCCCCCCCCCCCEEEEECCCHHHHHHCCCCCCCHHHHHHHHHHHHH
YGALRYARNITDVDDKINAAAQAQGVPISTITDRFAAIYRQDMAALGVVPPDIEPEATAH
HHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
IPQIVAMIEQLIANGHAYAAEGHVLFSVSSFEDYGKLSRRDPDEMLAGARVDVAPYKRDP
HHHHHHHHHHHHHCCCEEEECCEEEEEECCCHHHHHHCCCCHHHHHCCCCEEECCCCCCC
GDFVLWKPSSDELPGWESPWGRGRPGWHIECSAMAAAHLGPTIDIHAGGVDLQFPHHENE
CCEEEECCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCEEEEECCCEEEECCCCCHH
IAQSECAHGGATFARFWLHNGMLNFSGAKMSKSLGNIETVHDLIAKHPPEALRYALLSAH
HHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHH
YRQPLDWSDGLIEQATNTLDRLYGTLRDLAALEACGSSGVEVSKTIPVEVESALQDDLNT
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHCCC
PLALSVIASIASEARALRNELVHGGEPSARMSELHAVRAKLLGAGLALGLLQQDPAAWFS
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
RGTDADDDARITALVQERSAAKKAKDFARADAIRKQLADEGIVLEDTPQGVRWKRA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]