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The map label for this gene is moeB [H]

Identifier: 84624035

GI number: 84624035

Start: 2638591

End: 2639730

Strand: Direct

Name: moeB [H]

Synonym: XOO_2378

Alternate gene names: 84624035

Gene position: 2638591-2639730 (Clockwise)

Preceding gene: 84624034

Following gene: 84624036

Centisome position: 53.41

GC content: 64.82

Gene sequence:

>1140_bases
ATGAGCAGCCATGACATCTCCCCTGCCGACGCCCGTGCCCGCGCCTTGCAAGGCGCGTTGCTGATCGACATCCGGCAACT
GCATGAACGCGCTAGCGGCCAGGCCGAAGGCGCCTTAGCCATCGCACAGAATGCCCTGGAAACAGAGCCGGCCACGCATT
TGCCCGAGCACGCCCGCGAAATTGTGCTGATCTGCCAGCGTGGCAAACGCTCGGCGCACACGGCCGCCATCTTGCGCGCG
CACGGCTATGCGCGCGTGGCGTCCGTGGCCGGTGGCACTAGTGCCTGGGCGAGCGACGGCCTGCCGTTGGTGCGCCCCAC
GCTGCCGCCGGATGAGCAGGATTTTCTAGAGCGCTATTCGCGCCATCTGCGTCTGTCGCAGGTCGGCGTGGAAGGTCAGC
GGCGGCTGGCGCGTGCGCGCGTGCTGCTGGTCGGCGCAGGCGGGTTGGGCTCGCCTGCAGCGTTCTACCTTGCGGCAGCC
GGTGTCGGACATCTGAGCATCGCCGACGACGATGTAGTGGACCGCAGCAATCTGCAACGCCAGATTCTGCACACTGAAGA
CAGCGTCGGCACGGCCAAGGTCGACTCCGCCGCACAGCGCATTGCCGCGCTCAACCCACGCGTGGGCATCGAGGCGGTGC
AAACGCGCGTGACTGCCGACAATGTCGAAGCACTGCTGCAGGACGTGGATGTGGTAGTGGATGGTGCAGACAATTTTCCC
GCGCGGTATTTACTCAACGATGCCTGCGTCAAACGCGGTAAACCACTGGTTTACGGCGCCGTGCAACAGTTCGAAGGACA
GGTGAGCGTGTTCGATGCCGGCCGCAACCGTGGCCGTGCGCCCTGCTACCGCTGCCTGTTTCCAGAACCGCCGCCGCCGG
AATTTGCGCCCAGCTGTGCCGAGGCTGGTGTGCTCGGCGTGCTGCCCGGTGTCATCGGTTTATTGCAGGCCACCGAGGTG
ATCAAGTTGCTGCTTGGGATTGGCGACAGCCTGACTGGCCGTCTGCTCAGTTTCGATGCATTGGCCATGCGCTTCCGCGA
CATCCGCTTGCCGCCGGATCCGCACTGCACGGTGTGTGCGCCTGGCGTGGTATTCGGCGGCTATGCGGATTACGCGGCAT
TCTGCGCTAGGGCCTGTTAA

Upstream 100 bases:

>100_bases
CATTGCAGATCATGGAGCGTCTTTCACTTTCCATGCCATTGCTTGGATCTCGCCGGAAGACTGCACATCGCAGCAGCAAC
ATTTGCGCGACAATAGTCCT

Downstream 100 bases:

>100_bases
CACATCCGAAGCCCATCAACGACCAGAACGAAGCTGAGGAAGCCAAGGAACATGACATCCAGCTTCTCGAAGCGCGTGAA
AATCCGTCGGTAGCCCTTCA

Product: molybdopterin biosynthesis protein MoeB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MSSHDISPADARARALQGALLIDIRQLHERASGQAEGALAIAQNALETEPATHLPEHAREIVLICQRGKRSAHTAAILRA
HGYARVASVAGGTSAWASDGLPLVRPTLPPDEQDFLERYSRHLRLSQVGVEGQRRLARARVLLVGAGGLGSPAAFYLAAA
GVGHLSIADDDVVDRSNLQRQILHTEDSVGTAKVDSAAQRIAALNPRVGIEAVQTRVTADNVEALLQDVDVVVDGADNFP
ARYLLNDACVKRGKPLVYGAVQQFEGQVSVFDAGRNRGRAPCYRCLFPEPPPPEFAPSCAEAGVLGVLPGVIGLLQATEV
IKLLLGIGDSLTGRLLSFDALAMRFRDIRLPPDPHCTVCAPGVVFGGYADYAAFCARAC

Sequences:

>Translated_379_residues
MSSHDISPADARARALQGALLIDIRQLHERASGQAEGALAIAQNALETEPATHLPEHAREIVLICQRGKRSAHTAAILRA
HGYARVASVAGGTSAWASDGLPLVRPTLPPDEQDFLERYSRHLRLSQVGVEGQRRLARARVLLVGAGGLGSPAAFYLAAA
GVGHLSIADDDVVDRSNLQRQILHTEDSVGTAKVDSAAQRIAALNPRVGIEAVQTRVTADNVEALLQDVDVVVDGADNFP
ARYLLNDACVKRGKPLVYGAVQQFEGQVSVFDAGRNRGRAPCYRCLFPEPPPPEFAPSCAEAGVLGVLPGVIGLLQATEV
IKLLLGIGDSLTGRLLSFDALAMRFRDIRLPPDPHCTVCAPGVVFGGYADYAAFCARAC
>Mature_378_residues
SSHDISPADARARALQGALLIDIRQLHERASGQAEGALAIAQNALETEPATHLPEHAREIVLICQRGKRSAHTAAILRAH
GYARVASVAGGTSAWASDGLPLVRPTLPPDEQDFLERYSRHLRLSQVGVEGQRRLARARVLLVGAGGLGSPAAFYLAAAG
VGHLSIADDDVVDRSNLQRQILHTEDSVGTAKVDSAAQRIAALNPRVGIEAVQTRVTADNVEALLQDVDVVVDGADNFPA
RYLLNDACVKRGKPLVYGAVQQFEGQVSVFDAGRNRGRAPCYRCLFPEPPPPEFAPSCAEAGVLGVLPGVIGLLQATEVI
KLLLGIGDSLTGRLLSFDALAMRFRDIRLPPDPHCTVCAPGVVFGGYADYAAFCARAC

Specific function: Involved In The Biosynthesis Of A Demolybdo Cofactor (Molybdopterin), Necessary For Molybdoenzymes. Plays A Role In The Activation Of The Small Subunit Of The Molybdopterin Converting Factor (Moad). [C]

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=274, Percent_Identity=47.4452554744526, Blast_Score=199, Evalue=4e-51,
Organism=Homo sapiens, GI4885649, Length=173, Percent_Identity=32.9479768786127, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI23510338, Length=169, Percent_Identity=29.585798816568, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI23510340, Length=169, Percent_Identity=29.585798816568, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1787048, Length=248, Percent_Identity=42.741935483871, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI87082356, Length=249, Percent_Identity=42.1686746987952, Blast_Score=168, Evalue=6e-43,
Organism=Escherichia coli, GI1789177, Length=166, Percent_Identity=33.1325301204819, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17540406, Length=259, Percent_Identity=42.4710424710425, Blast_Score=212, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI193203301, Length=172, Percent_Identity=29.0697674418605, Blast_Score=82, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6321903, Length=212, Percent_Identity=41.9811320754717, Blast_Score=171, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6322639, Length=164, Percent_Identity=28.6585365853659, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6325438, Length=121, Percent_Identity=31.404958677686, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24582879, Length=264, Percent_Identity=46.5909090909091, Blast_Score=240, Evalue=9e-64,
Organism=Drosophila melanogaster, GI24660640, Length=154, Percent_Identity=32.4675324675325, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24641311, Length=260, Percent_Identity=30.3846153846154, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI20129973, Length=181, Percent_Identity=28.7292817679558, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28573937, Length=168, Percent_Identity=29.1666666666667, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 40234; Mature: 40103

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSHDISPADARARALQGALLIDIRQLHERASGQAEGALAIAQNALETEPATHLPEHARE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHHHHH
IVLICQRGKRSAHTAAILRAHGYARVASVAGGTSAWASDGLPLVRPTLPPDEQDFLERYS
HHHHHHCCCCCHHHHHHHHHCCHHHHHHHCCCCCHHHCCCCCEECCCCCCCHHHHHHHHH
RHLRLSQVGVEGQRRLARARVLLVGAGGLGSPAAFYLAAAGVGHLSIADDDVVDRSNLQR
HHHHHHHHCCHHHHHHHHEEEEEEECCCCCCHHHHHHHHCCCCCEEECCCCHHCHHHHHH
QILHTEDSVGTAKVDSAAQRIAALNPRVGIEAVQTRVTADNVEALLQDVDVVVDGADNFP
HHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCC
ARYLLNDACVKRGKPLVYGAVQQFEGQVSVFDAGRNRGRAPCYRCLFPEPPPPEFAPSCA
HHHHHHHHHHHCCCCEEEHHHHHHCCCEEEEECCCCCCCCCEEEECCCCCCCCCCCCCHH
EAGVLGVLPGVIGLLQATEVIKLLLGIGDSLTGRLLSFDALAMRFRDIRLPPDPHCTVCA
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEC
PGVVFGGYADYAAFCARAC
CCCEECCHHHHHHHHHHCC
>Mature Secondary Structure 
SSHDISPADARARALQGALLIDIRQLHERASGQAEGALAIAQNALETEPATHLPEHARE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHHHHH
IVLICQRGKRSAHTAAILRAHGYARVASVAGGTSAWASDGLPLVRPTLPPDEQDFLERYS
HHHHHHCCCCCHHHHHHHHHCCHHHHHHHCCCCCHHHCCCCCEECCCCCCCHHHHHHHHH
RHLRLSQVGVEGQRRLARARVLLVGAGGLGSPAAFYLAAAGVGHLSIADDDVVDRSNLQR
HHHHHHHHCCHHHHHHHHEEEEEEECCCCCCHHHHHHHHCCCCCEEECCCCHHCHHHHHH
QILHTEDSVGTAKVDSAAQRIAALNPRVGIEAVQTRVTADNVEALLQDVDVVVDGADNFP
HHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCC
ARYLLNDACVKRGKPLVYGAVQQFEGQVSVFDAGRNRGRAPCYRCLFPEPPPPEFAPSCA
HHHHHHHHHHHCCCCEEEHHHHHHCCCEEEEECCCCCCCCCEEEECCCCCCCCCCCCCHH
EAGVLGVLPGVIGLLQATEVIKLLLGIGDSLTGRLLSFDALAMRFRDIRLPPDPHCTVCA
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEC
PGVVFGGYADYAAFCARAC
CCCEECCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA