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The map label for this gene is nhaR [H]

Identifier: 84623723

GI number: 84623723

Start: 2288621

End: 2289511

Strand: Direct

Name: nhaR [H]

Synonym: XOO_2066

Alternate gene names: 84623723

Gene position: 2288621-2289511 (Clockwise)

Preceding gene: 84623720

Following gene: 84623724

Centisome position: 46.33

GC content: 65.66

Gene sequence:

>891_bases
ATGGCGGCCTTGAACTACAACCACTTGCGCTACTTTTGGGCGGTCGCGCACGACGGCAATCTCACCCGCACGGCCGAGCG
CCTCAATCTCACCCAGTCGGCGTTGTCGGTGCAGATTCGCAAACTGGAAGAGCGCCTTGGCCATGCGCTGTTCGAACGCC
GCGGGCGGCAACTGCATCTGACCGAAGCCGGGCAGATCGTGCTGGACCATGCCGATGCGATCTTTGCCACCGGCGAGGAG
CTGCTCGGCACGCTGCGGCAGACGGGTGCGGCGCGGCAGGCGCTGCGTGTCGGCTCGCTGGCCACGCTGTCGCGTAACTT
CCAGATGGAGTTCATGCGCCCGCTGCTGGGCCGCACCGACATCGATCTGATTCTGCGTTCGGGCAGCGCGGGCGAACTGC
TGCGGGCGCTGGAGGCGCTCAACCTCGATGTGGTGCTGCTCAATCGGGCACCGGCCGGTGACGCGCTGTCGCCATTCGTC
ACCGACCGGCTTGCCGAGTACCCGGTCAGCCTGGTGGGGACACCGGATCGGTTGGGTCATGCCGCCAGCTTCGCCGAGCG
GCTGCGCAATCACCCCATCATCTTGCCCACGGTCGATAGCAGCGTGCGCATCGGCTTCGACGCCTTGGCAGATCGCCTGG
GCGTGCGGCCGCAGATCGTGGCGGAAGTCGAGGACATGGCGATGATGCGACTGCTTGCCCGCGAAGACATCGGCCTGGCC
GTTCTGCCGCCGATCGTGGTCAAGGACGAGATTGCCGCCGGGGCGCTGATGGAAGGCGATCAATTGCCGGACATCGTGGA
GACGTTCCATGCGGTCACCATGTCGCGGCGCTTTCCGAATCCGTTGGTGCGGCTTCTGCTTCAGCCCGCAGCTTTGTCTG
GAAGCCTGTAG

Upstream 100 bases:

>100_bases
CTCAGAACGAGCGTGGTGGCGGGCTGCGCCACGATAGCGATCGGTGGGGTTGAAGAAAAATTCATTGTTGTTGCGAATTT
GTTCGTTATTATCGAATGAT

Downstream 100 bases:

>100_bases
CTCCAAGTCGATGTCGCGATGGGGCATGGACTTAAGACTTAGAGCGGCTAACAAAACGTAGCGAGCAGCCGCCAGGCGAG
CGCGGCCGGTGCTCGGAATC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Na(+)/H(+) antiporter regulatory protein [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MAALNYNHLRYFWAVAHDGNLTRTAERLNLTQSALSVQIRKLEERLGHALFERRGRQLHLTEAGQIVLDHADAIFATGEE
LLGTLRQTGAARQALRVGSLATLSRNFQMEFMRPLLGRTDIDLILRSGSAGELLRALEALNLDVVLLNRAPAGDALSPFV
TDRLAEYPVSLVGTPDRLGHAASFAERLRNHPIILPTVDSSVRIGFDALADRLGVRPQIVAEVEDMAMMRLLAREDIGLA
VLPPIVVKDEIAAGALMEGDQLPDIVETFHAVTMSRRFPNPLVRLLLQPAALSGSL

Sequences:

>Translated_296_residues
MAALNYNHLRYFWAVAHDGNLTRTAERLNLTQSALSVQIRKLEERLGHALFERRGRQLHLTEAGQIVLDHADAIFATGEE
LLGTLRQTGAARQALRVGSLATLSRNFQMEFMRPLLGRTDIDLILRSGSAGELLRALEALNLDVVLLNRAPAGDALSPFV
TDRLAEYPVSLVGTPDRLGHAASFAERLRNHPIILPTVDSSVRIGFDALADRLGVRPQIVAEVEDMAMMRLLAREDIGLA
VLPPIVVKDEIAAGALMEGDQLPDIVETFHAVTMSRRFPNPLVRLLLQPAALSGSL
>Mature_295_residues
AALNYNHLRYFWAVAHDGNLTRTAERLNLTQSALSVQIRKLEERLGHALFERRGRQLHLTEAGQIVLDHADAIFATGEEL
LGTLRQTGAARQALRVGSLATLSRNFQMEFMRPLLGRTDIDLILRSGSAGELLRALEALNLDVVLLNRAPAGDALSPFVT
DRLAEYPVSLVGTPDRLGHAASFAERLRNHPIILPTVDSSVRIGFDALADRLGVRPQIVAEVEDMAMMRLLAREDIGLAV
LPPIVVKDEIAAGALMEGDQLPDIVETFHAVTMSRRFPNPLVRLLLQPAALSGSL

Specific function: Plays a role in the positive regulation of nhaA (Probable) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786202, Length=288, Percent_Identity=26.3888888888889, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI157672245, Length=252, Percent_Identity=29.3650793650794, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI2367136, Length=250, Percent_Identity=28.8, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788297, Length=244, Percent_Identity=26.6393442622951, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787530, Length=272, Percent_Identity=26.8382352941176, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790399, Length=147, Percent_Identity=29.9319727891156, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1788748, Length=265, Percent_Identity=26.4150943396226, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32451; Mature: 32320

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAALNYNHLRYFWAVAHDGNLTRTAERLNLTQSALSVQIRKLEERLGHALFERRGRQLHL
CCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
TEAGQIVLDHADAIFATGEELLGTLRQTGAARQALRVGSLATLSRNFQMEFMRPLLGRTD
ECCCEEEEECCCHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHCHHHHHHHHHHCCCC
IDLILRSGSAGELLRALEALNLDVVLLNRAPAGDALSPFVTDRLAEYPVSLVGTPDRLGH
CHHEEECCCHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHCCCEEECCCHHHHH
AASFAERLRNHPIILPTVDSSVRIGFDALADRLGVRPQIVAEVEDMAMMRLLAREDIGLA
HHHHHHHHCCCCEEEEECCCCCEECHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEE
VLPPIVVKDEIAAGALMEGDQLPDIVETFHAVTMSRRFPNPLVRLLLQPAALSGSL
ECCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
AALNYNHLRYFWAVAHDGNLTRTAERLNLTQSALSVQIRKLEERLGHALFERRGRQLHL
CCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
TEAGQIVLDHADAIFATGEELLGTLRQTGAARQALRVGSLATLSRNFQMEFMRPLLGRTD
ECCCEEEEECCCHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHCHHHHHHHHHHCCCC
IDLILRSGSAGELLRALEALNLDVVLLNRAPAGDALSPFVTDRLAEYPVSLVGTPDRLGH
CHHEEECCCHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHCCCEEECCCHHHHH
AASFAERLRNHPIILPTVDSSVRIGFDALADRLGVRPQIVAEVEDMAMMRLLAREDIGLA
HHHHHHHHCCCCEEEEECCCCCEECHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEE
VLPPIVVKDEIAAGALMEGDQLPDIVETFHAVTMSRRFPNPLVRLLLQPAALSGSL
ECCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8231807; 9457888; 10952301 [H]