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The map label for this gene is pdxK [H]

Identifier: 84623572

GI number: 84623572

Start: 2113969

End: 2114877

Strand: Direct

Name: pdxK [H]

Synonym: XOO_1915

Alternate gene names: 84623572

Gene position: 2113969-2114877 (Clockwise)

Preceding gene: 84623571

Following gene: 84623573

Centisome position: 42.79

GC content: 67.88

Gene sequence:

>909_bases
ATGAGCGATGCAACCGACAGCCACCTCGTCCATGGTCGCCGCCAGCGTCCGGATGGCCCTTCGCCGATCGATGTGATTTC
GGTGCAATCGCAATTGGTCTATGGCCATGCCGGCAACAGCGCTGCGGTGCCGCCGCTGCGCGCGCTGGGACTGCGTGTGG
CCGAAGTGCCCACCACGCTGCTGAGCAATGCGCCGTTCTACGCGACCCTGCGCGGACGCATTCTGCCAGCCGACTGGCTG
GCGGATTTGTTGCTGGGCGCCACCGAACGTGGCTTGCCACAACGTGCACGCATGCTGGTGTCCGGCTATTTCGGCAGCCT
GGCCAATGGCGACGCCTTTGCCGACTGGCTGGAGCAGACCTTGCCGCAGGCGCCGCAGCTGCGCTATTGCCTGGACCCGG
TGATCGGCGACACGCACACCGGCCCGTACGTCGAACCCGGGCTGGAGCGCGTGTTCGCCGAGCGACTGCTACCGCATGCC
TGGCTGGTGACACCCAATGCGTTCGAGCTGGGTCTGCTGACCGGCCTGCCAAGCCTGCAGCAGGACGATGCCATCGCCGC
CGCGCGCGCGTTGCTGGCACGCGGGCCGCAATGGGTGCTAGCGCACAGCGTGGCCGGTGCCGCAGGTGAGCTGGTGACCT
TGGCGGTCAGCGATACGGCAGTGTATCGCTGGGCCAGCCCGCACCTGCCGGTGGATGTCGCCGGCACCGGCGATGTGTTG
ATGGCGCTGCTGATCGGCCTGTTGTTGCGCGATGTGCCGTTCGAACAGGCAGTGGGGCACGCGCTCAGCGGCGTGCATGG
CGCGCTGGAAGCGACGCTGGCCGCAGGTTTCGAAGAGTTCGACGTGCTGGCTGCAGCGCCGGCCGCACTGGCCGCTGCGC
CGCGATTTGCCGTCGAGCGATGGGCATGA

Upstream 100 bases:

>100_bases
CTGTTCAACAGCGCCAATGCCGTTGACGTGGTTCATCCACGACATCCTTGCAAGGTTACGCGGATAATCGTTGCCATCTC
TTCCCAACACGGCCGCCCGC

Downstream 100 bases:

>100_bases
TCGCGCAGCCGGTGGTCGGCATCGTTGGCATCGCCGGCGCGTACGGGCGCTGGCTGGCGCAGTTCCTGCGCACGCGTATG
CAGCTGGAGGTGATCGGGTT

Product: pyridoxine kinase

Products: NA

Alternate protein names: PN/PL/PM kinase; Pyridoxal kinase; Pyridoxamine kinase; Vitamin B6 kinase [H]

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MSDATDSHLVHGRRQRPDGPSPIDVISVQSQLVYGHAGNSAAVPPLRALGLRVAEVPTTLLSNAPFYATLRGRILPADWL
ADLLLGATERGLPQRARMLVSGYFGSLANGDAFADWLEQTLPQAPQLRYCLDPVIGDTHTGPYVEPGLERVFAERLLPHA
WLVTPNAFELGLLTGLPSLQQDDAIAAARALLARGPQWVLAHSVAGAAGELVTLAVSDTAVYRWASPHLPVDVAGTGDVL
MALLIGLLLRDVPFEQAVGHALSGVHGALEATLAAGFEEFDVLAAAPAALAAAPRFAVERWA

Sequences:

>Translated_302_residues
MSDATDSHLVHGRRQRPDGPSPIDVISVQSQLVYGHAGNSAAVPPLRALGLRVAEVPTTLLSNAPFYATLRGRILPADWL
ADLLLGATERGLPQRARMLVSGYFGSLANGDAFADWLEQTLPQAPQLRYCLDPVIGDTHTGPYVEPGLERVFAERLLPHA
WLVTPNAFELGLLTGLPSLQQDDAIAAARALLARGPQWVLAHSVAGAAGELVTLAVSDTAVYRWASPHLPVDVAGTGDVL
MALLIGLLLRDVPFEQAVGHALSGVHGALEATLAAGFEEFDVLAAAPAALAAAPRFAVERWA
>Mature_301_residues
SDATDSHLVHGRRQRPDGPSPIDVISVQSQLVYGHAGNSAAVPPLRALGLRVAEVPTTLLSNAPFYATLRGRILPADWLA
DLLLGATERGLPQRARMLVSGYFGSLANGDAFADWLEQTLPQAPQLRYCLDPVIGDTHTGPYVEPGLERVFAERLLPHAW
LVTPNAFELGLLTGLPSLQQDDAIAAARALLARGPQWVLAHSVAGAAGELVTLAVSDTAVYRWASPHLPVDVAGTGDVLM
ALLIGLLLRDVPFEQAVGHALSGVHGALEATLAAGFEEFDVLAAAPAALAAAPRFAVERWA

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxal, pyridoxine, and pyridoxamine as substrates [H]

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505701, Length=182, Percent_Identity=32.4175824175824, Blast_Score=95, Evalue=9e-20,
Organism=Escherichia coli, GI1788758, Length=240, Percent_Identity=39.1666666666667, Blast_Score=164, Evalue=8e-42,
Organism=Escherichia coli, GI1787924, Length=268, Percent_Identity=30.9701492537313, Blast_Score=120, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17507759, Length=226, Percent_Identity=33.1858407079646, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17507757, Length=236, Percent_Identity=31.7796610169492, Blast_Score=103, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6324354, Length=244, Percent_Identity=27.8688524590164, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI45553007, Length=261, Percent_Identity=27.2030651340996, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013749
- InterPro:   IPR004625 [H]

Pfam domain/function: PF08543 Phos_pyr_kin [H]

EC number: =2.7.1.35 [H]

Molecular weight: Translated: 31907; Mature: 31776

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDATDSHLVHGRRQRPDGPSPIDVISVQSQLVYGHAGNSAAVPPLRALGLRVAEVPTTL
CCCCCCCHHHCCCCCCCCCCCCEEEEEHHHHEEEEECCCCCCCCCHHHHCCHHHHHHHHH
LSNAPFYATLRGRILPADWLADLLLGATERGLPQRARMLVSGYFGSLANGDAFADWLEQT
HCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LPQAPQLRYCLDPVIGDTHTGPYVEPGLERVFAERLLPHAWLVTPNAFELGLLTGLPSLQ
CCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHCCCCCC
QDDAIAAARALLARGPQWVLAHSVAGAAGELVTLAVSDTAVYRWASPHLPVDVAGTGDVL
CCHHHHHHHHHHHCCCCCEEHHHHCCCCCCEEEEEECCCEEEEECCCCCCEEECCCHHHH
MALLIGLLLRDVPFEQAVGHALSGVHGALEATLAAGFEEFDVLAAAPAALAAAPRFAVER
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCHHHHHHCCHHHHHC
WA
CC
>Mature Secondary Structure 
SDATDSHLVHGRRQRPDGPSPIDVISVQSQLVYGHAGNSAAVPPLRALGLRVAEVPTTL
CCCCCCHHHCCCCCCCCCCCCEEEEEHHHHEEEEECCCCCCCCCHHHHCCHHHHHHHHH
LSNAPFYATLRGRILPADWLADLLLGATERGLPQRARMLVSGYFGSLANGDAFADWLEQT
HCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LPQAPQLRYCLDPVIGDTHTGPYVEPGLERVFAERLLPHAWLVTPNAFELGLLTGLPSLQ
CCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHCCCCCC
QDDAIAAARALLARGPQWVLAHSVAGAAGELVTLAVSDTAVYRWASPHLPVDVAGTGDVL
CCHHHHHHHHHHHCCCCCEEHHHHCCCCCCEEEEEECCCEEEEECCCCCCEEECCCHHHH
MALLIGLLLRDVPFEQAVGHALSGVHGALEATLAAGFEEFDVLAAAPAALAAAPRFAVER
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCHHHHHHCCHHHHHC
WA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]