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The map label for this gene is czcD [H]

Identifier: 84623400

GI number: 84623400

Start: 1925540

End: 1926505

Strand: Direct

Name: czcD [H]

Synonym: XOO_1743

Alternate gene names: 84623400

Gene position: 1925540-1926505 (Clockwise)

Preceding gene: 84623399

Following gene: 84623402

Centisome position: 38.98

GC content: 65.42

Gene sequence:

>966_bases
ATGGGACACGACCACAACCACGCACCCAGCGAAATTCGCCATGAAACACCCTTGTGGTGGGCGCTGGGCCTGACCGCCAC
GTTCCTGTTGGCAGAGATCATCGGCGCGTTCGTGACCAACAGCCTGGCGCTGTTGTCCGACGCCGCCCATATGGCCACCG
ACACCGTCGGCCTGATGATCGCGTTGGTCGCGGTGCGCTTGAGCCGTCGCCCGGCTGACGCGCGTCGCACGTATGGCTAT
GTGCGGCTCGAAGCGCTCGGCGCGTTGGCCAATGGCGCGCTGCTGTTCGCAGTGGGCGGCTACATCCTGTGGGAGGCCGC
GCAGCGCGTTCGCGCCCCGCAGGACATTGCGTATGGCGGCATGCTGCTGATCGCCGGCTTCGGCCTGGTGATCAATCTGA
TCGCAATGAAGCTGCTGCATGCCGGCAGCGGCGAAAGCCTCAACGTCAAAGGCGCCTATCTGGAGGTCTGGAGCGACATG
CTCGGATCGATGGCGGTGATCATCGGTGCCTTGCTGATCCACTGGACCAGCTGGCAGTGGATCGACCCGGTGCTGGCCGT
GCTGATCGGCCTGTGGGTATTGCCGCGCACCTGGGTGCTGCTGCGCGAGGCGATCAACGTGTTGCTCGAGGGCGTGCCCA
AGGGTATCGATCTGGCCCAGGTGCAGCAGGCACTCACCAGCCATCCCGGCGTCGAAGACGTGCACGACCTACACGTCTGG
GCGCTGGCCTCCAGCACCCCTGCGCTCACCGCGCACATTGTCGTCAACGAGGCAACCGACCGCGACCGCCTGCGCGACGC
GCTCGCCACCCTGCTGCACGACCGCTTCGACATCGTCCATGTCACCCTGCAGGTGGAAAGCGGCGACTGCGGCACCGAGC
CTTGCGGCACACCAAAGCCCGCTGCAGACGCTGGCCATGACGCGCATCATGGGCACAGTCATGCGCATGGGCACTCCCAT
CATTAA

Upstream 100 bases:

>100_bases
CCGCATGACGCGTGTGATGTGATGTCATCACATGCAGGTGTAATAGTCTCCGCCATCGCGTGCGGCTAAGGTGCGCGCAT
CGCACGAGACGACGACCTCC

Downstream 100 bases:

>100_bases
CCTCTGGTGGGAGCAGGTCGGCGGGGCATCGAATTAGCGCGTTTCGACCTGCACCATCAACAGGAAGCGGGAGGCCCTGG
CGCGACATATCCAGATCGAT

Product: cobalt-zinc-cadmium resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MGHDHNHAPSEIRHETPLWWALGLTATFLLAEIIGAFVTNSLALLSDAAHMATDTVGLMIALVAVRLSRRPADARRTYGY
VRLEALGALANGALLFAVGGYILWEAAQRVRAPQDIAYGGMLLIAGFGLVINLIAMKLLHAGSGESLNVKGAYLEVWSDM
LGSMAVIIGALLIHWTSWQWIDPVLAVLIGLWVLPRTWVLLREAINVLLEGVPKGIDLAQVQQALTSHPGVEDVHDLHVW
ALASSTPALTAHIVVNEATDRDRLRDALATLLHDRFDIVHVTLQVESGDCGTEPCGTPKPAADAGHDAHHGHSHAHGHSH
H

Sequences:

>Translated_321_residues
MGHDHNHAPSEIRHETPLWWALGLTATFLLAEIIGAFVTNSLALLSDAAHMATDTVGLMIALVAVRLSRRPADARRTYGY
VRLEALGALANGALLFAVGGYILWEAAQRVRAPQDIAYGGMLLIAGFGLVINLIAMKLLHAGSGESLNVKGAYLEVWSDM
LGSMAVIIGALLIHWTSWQWIDPVLAVLIGLWVLPRTWVLLREAINVLLEGVPKGIDLAQVQQALTSHPGVEDVHDLHVW
ALASSTPALTAHIVVNEATDRDRLRDALATLLHDRFDIVHVTLQVESGDCGTEPCGTPKPAADAGHDAHHGHSHAHGHSH
H
>Mature_320_residues
GHDHNHAPSEIRHETPLWWALGLTATFLLAEIIGAFVTNSLALLSDAAHMATDTVGLMIALVAVRLSRRPADARRTYGYV
RLEALGALANGALLFAVGGYILWEAAQRVRAPQDIAYGGMLLIAGFGLVINLIAMKLLHAGSGESLNVKGAYLEVWSDML
GSMAVIIGALLIHWTSWQWIDPVLAVLIGLWVLPRTWVLLREAINVLLEGVPKGIDLAQVQQALTSHPGVEDVHDLHVWA
LASSTPALTAHIVVNEATDRDRLRDALATLLHDRFDIVHVTLQVESGDCGTEPCGTPKPAADAGHDAHHGHSHAHGHSHH

Specific function: Necessary for activation of the czc determinant [H]

COG id: COG1230

COG function: function code P; Co/Zn/Cd efflux system component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily [H]

Homologues:

Organism=Homo sapiens, GI52352805, Length=315, Percent_Identity=30.4761904761905, Blast_Score=170, Evalue=1e-42,
Organism=Homo sapiens, GI21361112, Length=304, Percent_Identity=30.2631578947368, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI289803013, Length=295, Percent_Identity=28.135593220339, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI289803009, Length=295, Percent_Identity=28.135593220339, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI289803007, Length=295, Percent_Identity=28.135593220339, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI289803003, Length=295, Percent_Identity=28.135593220339, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI64762489, Length=295, Percent_Identity=28.135593220339, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI21359890, Length=334, Percent_Identity=26.6467065868263, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI14210520, Length=234, Percent_Identity=30.3418803418803, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI20070323, Length=315, Percent_Identity=26.031746031746, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI52351208, Length=157, Percent_Identity=33.1210191082803, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI52352803, Length=232, Percent_Identity=26.2931034482759, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI222080086, Length=119, Percent_Identity=32.7731092436975, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI40255009, Length=119, Percent_Identity=32.7731092436975, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI1786966, Length=280, Percent_Identity=42.8571428571429, Blast_Score=188, Evalue=3e-49,
Organism=Escherichia coli, GI1790349, Length=245, Percent_Identity=24.0816326530612, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI193210990, Length=323, Percent_Identity=31.5789473684211, Blast_Score=171, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI17555794, Length=323, Percent_Identity=32.5077399380805, Blast_Score=167, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI17555796, Length=312, Percent_Identity=33.0128205128205, Blast_Score=165, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI32564488, Length=295, Percent_Identity=29.4915254237288, Blast_Score=124, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI17550440, Length=120, Percent_Identity=35.8333333333333, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17550442, Length=120, Percent_Identity=35.8333333333333, Blast_Score=78, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6320411, Length=173, Percent_Identity=30.0578034682081, Blast_Score=86, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6323899, Length=128, Percent_Identity=39.84375, Blast_Score=86, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6324892, Length=126, Percent_Identity=38.8888888888889, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24583858, Length=337, Percent_Identity=30.2670623145401, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI24656728, Length=323, Percent_Identity=29.4117647058824, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24656724, Length=323, Percent_Identity=29.4117647058824, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24656720, Length=323, Percent_Identity=29.4117647058824, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24656715, Length=323, Percent_Identity=29.4117647058824, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI21357035, Length=323, Percent_Identity=29.4117647058824, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI28574430, Length=151, Percent_Identity=31.7880794701987, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24584409, Length=151, Percent_Identity=31.7880794701987, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24585900, Length=125, Percent_Identity=37.6, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24585898, Length=125, Percent_Identity=37.6, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24585896, Length=125, Percent_Identity=37.6, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI19921672, Length=125, Percent_Identity=37.6, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24645863, Length=110, Percent_Identity=32.7272727272727, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 34610; Mature: 34479

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHDHNHAPSEIRHETPLWWALGLTATFLLAEIIGAFVTNSLALLSDAAHMATDTVGLMI
CCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALVAVRLSRRPADARRTYGYVRLEALGALANGALLFAVGGYILWEAAQRVRAPQDIAYGG
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
MLLIAGFGLVINLIAMKLLHAGSGESLNVKGAYLEVWSDMLGSMAVIIGALLIHWTSWQW
HHHHHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
IDPVLAVLIGLWVLPRTWVLLREAINVLLEGVPKGIDLAQVQQALTSHPGVEDVHDLHVW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHEE
ALASSTPALTAHIVVNEATDRDRLRDALATLLHDRFDIVHVTLQVESGDCGTEPCGTPKP
EEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCCCCC
AADAGHDAHHGHSHAHGHSHH
CCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GHDHNHAPSEIRHETPLWWALGLTATFLLAEIIGAFVTNSLALLSDAAHMATDTVGLMI
CCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALVAVRLSRRPADARRTYGYVRLEALGALANGALLFAVGGYILWEAAQRVRAPQDIAYGG
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
MLLIAGFGLVINLIAMKLLHAGSGESLNVKGAYLEVWSDMLGSMAVIIGALLIHWTSWQW
HHHHHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
IDPVLAVLIGLWVLPRTWVLLREAINVLLEGVPKGIDLAQVQQALTSHPGVEDVHDLHVW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHEE
ALASSTPALTAHIVVNEATDRDRLRDALATLLHDRFDIVHVTLQVESGDCGTEPCGTPKP
EEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCCCCC
AADAGHDAHHGHSHAHGHSHH
CCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]