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The map label for this gene is tolB [H]

Identifier: 84623209

GI number: 84623209

Start: 1708270

End: 1709589

Strand: Direct

Name: tolB [H]

Synonym: XOO_1552

Alternate gene names: 84623209

Gene position: 1708270-1709589 (Clockwise)

Preceding gene: 84623208

Following gene: 84623210

Centisome position: 34.58

GC content: 65.08

Gene sequence:

>1320_bases
ATGAAGAAACCGCTGCGTTGGCTAGCCGCCTTGACCGTCCTGTTGTTGCCGCTGAGCGCGCTCGCGCAGCAGCAAGGCCT
CACCATCGATATCGTCGGCGGTAGCGCTTCGGCCACGCCGATCGCCGTCATTCCGATGCCTTACCAGGGCTCCGGCACTG
CACCGCAGACCGATGTGTCTGCGGTGGTCGGCGCCGACCTTGATCGTTCCGGCCAGTTCCGCACGCTGCCGGCCGCGCAG
ATCGTCGAAAAGCCGACCCGTGGCACCGAGGTGCAGTTCCAGACCTGGCGCACCCTCAAGCAGAACTACATCGTGGTTGG
CCGCGTCATGAACGCGGGCGAAGGCGCCTATCGCGTGGAGTACGAGCTGTTCGATGTCGCGAAGGGCGAGCGCATGCTGG
GCCTGGCGATGACCGCGCGTGCCAACGCAATGCGCGATGTTTCGCACCAGATGGCCGATGCGATCTATGAAAAGATCACT
GGCGTGCGCGGCGCGTTCTGGACCCGCATCGCCTACGTGACTGCCAGCGGCAAGGGCGGCGCCATGCGTTATGCGCTGAT
GGTGGCCGATTCGGATGGCTACAATCCGCAGACCATCGTACGTTCGGCCGAGCCGTTGCTGTCGCCCAACTGGAGCCCGG
ACGGCAAGAAGCTGGCCTATGTGAGCTTTGAGCGCGGCAACTCGTCGATCTACCTGCAGGACATCGCCACCGGCGCGCGC
GAACTGGTCTCCAGCTTCCGCGGCATCAATGGCGCGCCGTCGTTCTCGCCGGATGGCCGTCGCCTGGCGCTGGCGCTGTC
GCGTAGTGGCAACCCGGAAATTTACGTGATGGACCTGGGCAGCAAGCAGCTCACCCAGCTCACCAACCACTTCGGCATCG
ACACCGAGCCGACCTGGGCGCCGGATGGCGGCAGCATCTACTTCACCTCTGATCGCGGCGGTCGTCCGCAGATCTACCAG
GTCGCGGCCAGCGGCGGCAGCGCCAACCGTGTCACCTTCCAGGGCAACTACAACGCCACCGCCAGTGTGTCGTTCGACGG
CAAGAAGATTGCCGTGGCACAGGGCAGTGGCAATACCTACCGCATCGCCATGATGGACCGCAGCCTGGGTTCGCCCAGCT
GGAGCACGCTGTCGCCGGGATCTCTGGACGAATCGCCGAGCTTCGCGCCTAACGCTAGCATGGTGTTGTACGCGGCGCGC
GAAGGCGGCCGTGGCGTGCTGTACGCCGTCTCTTCCGACGCTCGGGTCCGCCAGCGTCTAGTGCTGGCCGACGGCGATGT
GAGAGAACCCGCATGGGGGCCTTACCGAACCGCGCATTAA

Upstream 100 bases:

>100_bases
CGCTCGCTCCATTTTCACGTCAACTCATTCACGATTGCGCGTATGTTCACTCGCTGATTGCTATCCCTTGCACACTTTTC
CTGCCCGATCCGAGCCGTCC

Downstream 100 bases:

>100_bases
TGTTAATATTTCGCTGCGTTAAACCACTCATTGGCCCAGAGCCTCCATAGGTACCCCATGAACAAGTCCACCCGCGTCTT
GCTTGTCTCTCTATTGTCCG

Product: translocation protein TolB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MKKPLRWLAALTVLLLPLSALAQQQGLTIDIVGGSASATPIAVIPMPYQGSGTAPQTDVSAVVGADLDRSGQFRTLPAAQ
IVEKPTRGTEVQFQTWRTLKQNYIVVGRVMNAGEGAYRVEYELFDVAKGERMLGLAMTARANAMRDVSHQMADAIYEKIT
GVRGAFWTRIAYVTASGKGGAMRYALMVADSDGYNPQTIVRSAEPLLSPNWSPDGKKLAYVSFERGNSSIYLQDIATGAR
ELVSSFRGINGAPSFSPDGRRLALALSRSGNPEIYVMDLGSKQLTQLTNHFGIDTEPTWAPDGGSIYFTSDRGGRPQIYQ
VAASGGSANRVTFQGNYNATASVSFDGKKIAVAQGSGNTYRIAMMDRSLGSPSWSTLSPGSLDESPSFAPNASMVLYAAR
EGGRGVLYAVSSDARVRQRLVLADGDVREPAWGPYRTAH

Sequences:

>Translated_439_residues
MKKPLRWLAALTVLLLPLSALAQQQGLTIDIVGGSASATPIAVIPMPYQGSGTAPQTDVSAVVGADLDRSGQFRTLPAAQ
IVEKPTRGTEVQFQTWRTLKQNYIVVGRVMNAGEGAYRVEYELFDVAKGERMLGLAMTARANAMRDVSHQMADAIYEKIT
GVRGAFWTRIAYVTASGKGGAMRYALMVADSDGYNPQTIVRSAEPLLSPNWSPDGKKLAYVSFERGNSSIYLQDIATGAR
ELVSSFRGINGAPSFSPDGRRLALALSRSGNPEIYVMDLGSKQLTQLTNHFGIDTEPTWAPDGGSIYFTSDRGGRPQIYQ
VAASGGSANRVTFQGNYNATASVSFDGKKIAVAQGSGNTYRIAMMDRSLGSPSWSTLSPGSLDESPSFAPNASMVLYAAR
EGGRGVLYAVSSDARVRQRLVLADGDVREPAWGPYRTAH
>Mature_439_residues
MKKPLRWLAALTVLLLPLSALAQQQGLTIDIVGGSASATPIAVIPMPYQGSGTAPQTDVSAVVGADLDRSGQFRTLPAAQ
IVEKPTRGTEVQFQTWRTLKQNYIVVGRVMNAGEGAYRVEYELFDVAKGERMLGLAMTARANAMRDVSHQMADAIYEKIT
GVRGAFWTRIAYVTASGKGGAMRYALMVADSDGYNPQTIVRSAEPLLSPNWSPDGKKLAYVSFERGNSSIYLQDIATGAR
ELVSSFRGINGAPSFSPDGRRLALALSRSGNPEIYVMDLGSKQLTQLTNHFGIDTEPTWAPDGGSIYFTSDRGGRPQIYQ
VAASGGSANRVTFQGNYNATASVSFDGKKIAVAQGSGNTYRIAMMDRSLGSPSWSTLSPGSLDESPSFAPNASMVLYAAR
EGGRGVLYAVSSDARVRQRLVLADGDVREPAWGPYRTAH

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0823

COG function: function code U; Periplasmic component of the Tol biopolymer transport system

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tolB family [H]

Homologues:

Organism=Escherichia coli, GI1786961, Length=437, Percent_Identity=43.4782608695652, Blast_Score=338, Evalue=3e-94,
Organism=Caenorhabditis elegans, GI32564217, Length=210, Percent_Identity=26.6666666666667, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32564215, Length=210, Percent_Identity=27.1428571428571, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011659
- InterPro:   IPR014167
- InterPro:   IPR007195
- InterPro:   IPR015943 [H]

Pfam domain/function: PF07676 PD40; PF04052 TolB_N [H]

EC number: NA

Molecular weight: Translated: 47084; Mature: 47084

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKPLRWLAALTVLLLPLSALAQQQGLTIDIVGGSASATPIAVIPMPYQGSGTAPQTDVS
CCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCH
AVVGADLDRSGQFRTLPAAQIVEKPTRGTEVQFQTWRTLKQNYIVVGRVMNAGEGAYRVE
HEECCCCCCCCCEEECCHHHHHCCCCCCCEEEEHHHHHHHCCEEEEEEEECCCCCEEEEE
YELFDVAKGERMLGLAMTARANAMRDVSHQMADAIYEKITGVRGAFWTRIAYVTASGKGG
EEEEECCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCC
AMRYALMVADSDGYNPQTIVRSAEPLLSPNWSPDGKKLAYVSFERGNSSIYLQDIATGAR
EEEEEEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEHHHHHHHH
ELVSSFRGINGAPSFSPDGRRLALALSRSGNPEIYVMDLGSKQLTQLTNHFGIDTEPTWA
HHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCC
PDGGSIYFTSDRGGRPQIYQVAASGGSANRVTFQGNYNATASVSFDGKKIAVAQGSGNTY
CCCCEEEEECCCCCCCEEEEEEECCCCCCEEEEECCCCEEEEEEECCCEEEEEECCCCEE
RIAMMDRSLGSPSWSTLSPGSLDESPSFAPNASMVLYAAREGGRGVLYAVSSDARVRQRL
EEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCHHEEEEE
VLADGDVREPAWGPYRTAH
EEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKKPLRWLAALTVLLLPLSALAQQQGLTIDIVGGSASATPIAVIPMPYQGSGTAPQTDVS
CCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCH
AVVGADLDRSGQFRTLPAAQIVEKPTRGTEVQFQTWRTLKQNYIVVGRVMNAGEGAYRVE
HEECCCCCCCCCEEECCHHHHHCCCCCCCEEEEHHHHHHHCCEEEEEEEECCCCCEEEEE
YELFDVAKGERMLGLAMTARANAMRDVSHQMADAIYEKITGVRGAFWTRIAYVTASGKGG
EEEEECCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCC
AMRYALMVADSDGYNPQTIVRSAEPLLSPNWSPDGKKLAYVSFERGNSSIYLQDIATGAR
EEEEEEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEHHHHHHHH
ELVSSFRGINGAPSFSPDGRRLALALSRSGNPEIYVMDLGSKQLTQLTNHFGIDTEPTWA
HHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCC
PDGGSIYFTSDRGGRPQIYQVAASGGSANRVTFQGNYNATASVSFDGKKIAVAQGSGNTY
CCCCEEEEECCCCCCCEEEEEEECCCCCCEEEEECCCCEEEEEEECCCEEEEEECCCCEE
RIAMMDRSLGSPSWSTLSPGSLDESPSFAPNASMVLYAAREGGRGVLYAVSSDARVRQRL
EEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCHHEEEEE
VLADGDVREPAWGPYRTAH
EEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]