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The map label for this gene is acdA [H]

Identifier: 84623065

GI number: 84623065

Start: 1531307

End: 1532482

Strand: Direct

Name: acdA [H]

Synonym: XOO_1408

Alternate gene names: 84623065

Gene position: 1531307-1532482 (Clockwise)

Preceding gene: 84623064

Following gene: 84623066

Centisome position: 31.0

GC content: 65.9

Gene sequence:

>1176_bases
ATGACAGCCAACATGCCGGCACGCCCTGATGATCTGTTCGACGTACGCGCGCTTCTCACCGACGAAGAGCGGGCGGTGCA
GGAGGCGGTAGCGCGGTTTACCGATACGCGGGTGGTGCCGGCGATCGGCGATGCCTTCGATGCCGGGCGCTTCCCGCGCG
AGTGGATTCCAGACCTGGCGGAATTAGGGTTGCTGGGTGCCAGCCTGCCGGTTCGCGATGGCGGTGCGGGTCTGGGCGCG
GTGTCTTACGGACTGATCTGCCAGGAGCTGGAGCGCGGCGACAGCGGGCTGCGCAGCTTCGTCAGCGTGCAGTCTTCGTT
GTGCATGTATCCCATCCACGCCTATGGCAGCGACGAACAGCGGCAATGCTGGCTGCCGGAAATGGCGACCGGCAGGGTGA
TTGGCTGCTTCGGCCTGAGCGAGGCGCAGGGCGGGTCGGATCCTGCCGCGATGACGACGCGCGCGGTGCGCGAGGGCGAC
GGCTGGCGCTTGAATGGCGCCAAGATGTGGATCACCAACGGCAGCATTGCCGGGTTGGCGATCATCTGGGCGCATACGGA
CGATGGCGTGCGTGGCTTTTTGGTCGAGACCGACAGCGCCGGTTTCAGCGCGCACGACATCAGCCACAAGATGAGCCTGC
GTGCGTCGGTGACGTCGGGCCTGTTCCTGGACAACGTGTTCGTGCCGGAGCGGATGCGGCTGCCGGAGGCGGCCGGTTTG
AAGGCGCCACTGAGTTGCCTCAACCAGGCGCGCTACGGCATCGCCTGGGGCGTGATCGGCGCGGCGGTGGCCTGCCTGCG
CGAGGCGCTGACCTATGCCGGCGAACGCATCCTGTTCGGACGCCCGTTGGCGGCCACGCAGAGCGCGCAGATCAAACTGG
CCGACATGGCGCGAGGGATTTCGACCGCCCAGCTACTCGCCTTGCAGCTCGGCCGCTTGAAGGAAGCCGGTACGTTGCGG
CCGGAGCAGATCTCGCTGGCAAAATGGAATAATTGCCGCATGGCGCTGGATGTAGCGCGCGAATGCCGCGACCTGCTGGG
CGCGGCTGGCATCACCACCGAGCATGTGGCGATCCGGCATGCGCTGAACCTGGAATCGGTGATCACCTACGAGGGCACCG
AAACCGTGCATCAGCTGGTGGTGGGACGTGCGCTGACAGGACTCAATGCGTTTTGA

Upstream 100 bases:

>100_bases
AGCCGGCAGTGCCGGCTCTTTTCGTTTGTGCCATTCCCGGGCCGGCAGGCACCACCATGTTCGGCCGGCAACTGGCAGAT
AATCGCGTCTTCCGCTTGCG

Downstream 100 bases:

>100_bases
CAAGGAGTGGATGATTGATCAGCAAGGATGTGATGAAACGCCTGGGCGGCGTCTTCTGGAGCCGTGTGCTCCCTTGCCGG
CATGGCAATTGCCCCAGCGC

Product: glutaryl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MTANMPARPDDLFDVRALLTDEERAVQEAVARFTDTRVVPAIGDAFDAGRFPREWIPDLAELGLLGASLPVRDGGAGLGA
VSYGLICQELERGDSGLRSFVSVQSSLCMYPIHAYGSDEQRQCWLPEMATGRVIGCFGLSEAQGGSDPAAMTTRAVREGD
GWRLNGAKMWITNGSIAGLAIIWAHTDDGVRGFLVETDSAGFSAHDISHKMSLRASVTSGLFLDNVFVPERMRLPEAAGL
KAPLSCLNQARYGIAWGVIGAAVACLREALTYAGERILFGRPLAATQSAQIKLADMARGISTAQLLALQLGRLKEAGTLR
PEQISLAKWNNCRMALDVARECRDLLGAAGITTEHVAIRHALNLESVITYEGTETVHQLVVGRALTGLNAF

Sequences:

>Translated_391_residues
MTANMPARPDDLFDVRALLTDEERAVQEAVARFTDTRVVPAIGDAFDAGRFPREWIPDLAELGLLGASLPVRDGGAGLGA
VSYGLICQELERGDSGLRSFVSVQSSLCMYPIHAYGSDEQRQCWLPEMATGRVIGCFGLSEAQGGSDPAAMTTRAVREGD
GWRLNGAKMWITNGSIAGLAIIWAHTDDGVRGFLVETDSAGFSAHDISHKMSLRASVTSGLFLDNVFVPERMRLPEAAGL
KAPLSCLNQARYGIAWGVIGAAVACLREALTYAGERILFGRPLAATQSAQIKLADMARGISTAQLLALQLGRLKEAGTLR
PEQISLAKWNNCRMALDVARECRDLLGAAGITTEHVAIRHALNLESVITYEGTETVHQLVVGRALTGLNAF
>Mature_390_residues
TANMPARPDDLFDVRALLTDEERAVQEAVARFTDTRVVPAIGDAFDAGRFPREWIPDLAELGLLGASLPVRDGGAGLGAV
SYGLICQELERGDSGLRSFVSVQSSLCMYPIHAYGSDEQRQCWLPEMATGRVIGCFGLSEAQGGSDPAAMTTRAVREGDG
WRLNGAKMWITNGSIAGLAIIWAHTDDGVRGFLVETDSAGFSAHDISHKMSLRASVTSGLFLDNVFVPERMRLPEAAGLK
APLSCLNQARYGIAWGVIGAAVACLREALTYAGERILFGRPLAATQSAQIKLADMARGISTAQLLALQLGRLKEAGTLRP
EQISLAKWNNCRMALDVARECRDLLGAAGITTEHVAIRHALNLESVITYEGTETVHQLVVGRALTGLNAF

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4503943, Length=392, Percent_Identity=48.9795918367347, Blast_Score=355, Evalue=5e-98,
Organism=Homo sapiens, GI7669494, Length=372, Percent_Identity=48.6559139784946, Blast_Score=329, Evalue=3e-90,
Organism=Homo sapiens, GI4557233, Length=355, Percent_Identity=34.3661971830986, Blast_Score=198, Evalue=6e-51,
Organism=Homo sapiens, GI4501859, Length=373, Percent_Identity=31.9034852546917, Blast_Score=198, Evalue=8e-51,
Organism=Homo sapiens, GI4557231, Length=374, Percent_Identity=29.4117647058824, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI187960098, Length=374, Percent_Identity=29.4117647058824, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI226958412, Length=381, Percent_Identity=28.3464566929134, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI4501857, Length=380, Percent_Identity=28.1578947368421, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI226958414, Length=342, Percent_Identity=28.3625730994152, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI76496475, Length=407, Percent_Identity=27.2727272727273, Blast_Score=139, Evalue=7e-33,
Organism=Homo sapiens, GI4557235, Length=407, Percent_Identity=27.2727272727273, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI21361497, Length=396, Percent_Identity=26.7676767676768, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI7656849, Length=378, Percent_Identity=25.3968253968254, Blast_Score=119, Evalue=3e-27,
Organism=Escherichia coli, GI87081958, Length=346, Percent_Identity=26.5895953757225, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786223, Length=343, Percent_Identity=23.0320699708455, Blast_Score=82, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17534353, Length=387, Percent_Identity=44.1860465116279, Blast_Score=338, Evalue=3e-93,
Organism=Caenorhabditis elegans, GI17508101, Length=365, Percent_Identity=30.958904109589, Blast_Score=176, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17538396, Length=380, Percent_Identity=30.5263157894737, Blast_Score=168, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI17534899, Length=376, Percent_Identity=28.9893617021277, Blast_Score=164, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI17506239, Length=374, Percent_Identity=28.6096256684492, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17569725, Length=378, Percent_Identity=27.2486772486773, Blast_Score=157, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI17570075, Length=376, Percent_Identity=27.9255319148936, Blast_Score=141, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI71990804, Length=274, Percent_Identity=31.3868613138686, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI71985192, Length=359, Percent_Identity=26.4623955431755, Blast_Score=130, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI71985184, Length=305, Percent_Identity=28.5245901639344, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17533517, Length=376, Percent_Identity=23.936170212766, Blast_Score=122, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI32563615, Length=229, Percent_Identity=31.4410480349345, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI71982178, Length=271, Percent_Identity=28.7822878228782, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17551932, Length=352, Percent_Identity=26.9886363636364, Blast_Score=114, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI17505929, Length=349, Percent_Identity=26.0744985673352, Blast_Score=104, Evalue=9e-23,
Organism=Drosophila melanogaster, GI19920834, Length=386, Percent_Identity=46.6321243523316, Blast_Score=328, Evalue=5e-90,
Organism=Drosophila melanogaster, GI21356377, Length=372, Percent_Identity=32.258064516129, Blast_Score=192, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24660351, Length=377, Percent_Identity=31.5649867374005, Blast_Score=182, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24666513, Length=374, Percent_Identity=29.144385026738, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24646207, Length=376, Percent_Identity=31.9148936170213, Blast_Score=175, Evalue=4e-44,
Organism=Drosophila melanogaster, GI281363737, Length=344, Percent_Identity=30.2325581395349, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI21355753, Length=378, Percent_Identity=28.3068783068783, Blast_Score=142, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 41923; Mature: 41792

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00072 ACYL_COA_DH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTANMPARPDDLFDVRALLTDEERAVQEAVARFTDTRVVPAIGDAFDAGRFPREWIPDLA
CCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCHHHHHHHH
ELGLLGASLPVRDGGAGLGAVSYGLICQELERGDSGLRSFVSVQSSLCMYPIHAYGSDEQ
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHEEEEECCCCCCC
RQCWLPEMATGRVIGCFGLSEAQGGSDPAAMTTRAVREGDGWRLNGAKMWITNGSIAGLA
CEECCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCEEECCEEEEEECCCEEEEE
IIWAHTDDGVRGFLVETDSAGFSAHDISHKMSLRASVTSGLFLDNVFVPERMRLPEAAGL
EEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCEEECCCCCCHHHCCCHHCCC
KAPLSCLNQARYGIAWGVIGAAVACLREALTYAGERILFGRPLAATQSAQIKLADMARGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCEEHHHHHCCC
STAQLLALQLGRLKEAGTLRPEQISLAKWNNCRMALDVARECRDLLGAAGITTEHVAIRH
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ALNLESVITYEGTETVHQLVVGRALTGLNAF
HCCCCCEEEECCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TANMPARPDDLFDVRALLTDEERAVQEAVARFTDTRVVPAIGDAFDAGRFPREWIPDLA
CCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCHHHHHHHH
ELGLLGASLPVRDGGAGLGAVSYGLICQELERGDSGLRSFVSVQSSLCMYPIHAYGSDEQ
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHEEEEECCCCCCC
RQCWLPEMATGRVIGCFGLSEAQGGSDPAAMTTRAVREGDGWRLNGAKMWITNGSIAGLA
CEECCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCEEECCEEEEEECCCEEEEE
IIWAHTDDGVRGFLVETDSAGFSAHDISHKMSLRASVTSGLFLDNVFVPERMRLPEAAGL
EEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCEEECCCCCCHHHCCCHHCCC
KAPLSCLNQARYGIAWGVIGAAVACLREALTYAGERILFGRPLAATQSAQIKLADMARGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCEEHHHHHCCC
STAQLLALQLGRLKEAGTLRPEQISLAKWNNCRMALDVARECRDLLGAAGITTEHVAIRH
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ALNLESVITYEGTETVHQLVVGRALTGLNAF
HCCCCCEEEECCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]