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The map label for this gene is htpG [H]

Identifier: 84622924

GI number: 84622924

Start: 1388607

End: 1390475

Strand: Direct

Name: htpG [H]

Synonym: XOO_1267

Alternate gene names: 84622924

Gene position: 1388607-1390475 (Clockwise)

Preceding gene: 84622923

Following gene: 84622925

Centisome position: 28.11

GC content: 65.28

Gene sequence:

>1869_bases
ATGCAAGATCCCACTCCCGAGGCGACCGACGCCGCGCAGATCCGCCGTGCAGGCGTGGATCTCAATGGATTGATGTCGGT
CCTCAGCAAGCATCTGTACTCCACCCCGGTGGTCGCGCTGCGCGAGCTGGCGCAGAACGCGCACGATTCCATCCTGCGCC
GTCGTCTGGAACAACCCGATTGGCAGGGCGAATCGCGCGTTGAAGTGCATGCCGATGCCGCCCAGGGCATCGTGCGCATC
GTCGATACCGGTGCCGGACTGACCCAGCAGGAAATCCACGATTACCTGGCCACTGTGGGCGTGGGGTATACACGCGGCCT
ACGCCAGGGGGGACACGAGGACAGCGGCCTGATCGGCATGTTCGGGCTGGGGTTTTTATCTGCCTTCGTGCTGGCGCGGC
GGGTGACCGTACGCACCACCTCGTACCAGTCCCCGACGTTGGGCCATTGCTACATCTCCAGCAACGCCGAACAGTACACC
GTCAGCCCGATTCCAGCGCGTGCGCAGGTGGGCACGGAGGTGATGCTGGAACTGCACAGCGATTATTTGTTGTTGGCGCA
GGAAGGGCGGCTGCGCGAGATTCTGTCGCGCTATTGCGCGCTGTTGCGCGAGCCGATCTGGATCGGCGCCGATTCGCAGC
CGATCAATCCCGAGCCGCCGCCGTGGCGCATGCACGACGCCGTGCCGCTGCATCCGGTGCAGGCCTGGCGCCGTCAGCGC
GAGTTCGCTGCGCGCTTCGAGCGCAACTTCGAACCGTTGTGCTGCATGCCGGTGCGTGTGGAAGAGGGCAGCGATGCGGT
CGGCCTGTTATGGGTGCAGGACGGTGCGACCTACGGCACCAGCGACAACCGCAATCTGTCGGTGTTCCTGCGCGGCATGT
TGCTGGACGACAACGCGCGCGAACTGCTGCCGCCGTGGGCCGGTTTCATCGGTGGGGTGATCGAATCCAATCGGTTGACG
CCCACCGCAAGTCGCGAGGATCTGCAGCGCGATACGGTCTACAGCGCGGTGCAGCACGCCTTGTCCGAGGCATTGGTGCA
AGGCCTGGCCGACGTCGCACGTCAGCAACCGGAGGCATGGCGACGCATCCTGCTGCGTCATAACGAAGCGCTGCTGGGCG
CAGCGCTGTGCGATGAGCGCCTGTTCGAATTGCTGCTGGAACACGTGCGCGTGCCGACCTCGCAAGGCGATCTGCCGGCG
CAGCAACTGCCGGCACGCGGCGCGGTGCATGTGATTCTGGATAGCGACAGCGGTTTCGAAGAAATGCTGTTCCGCGCGAT
GGGCGTGCCGGTGGCGTATGGCAACCGGTATGCGGTGGTGCCGTTTTTGCGGCGCTGGGCGCAGGCCAAGGGTGTGCGCC
TGGTCGAGCTGGGCACCGAACAGGGCAATCGCCAGTTGTTTCATCTTGACACGCTGCCGGCCGATGAACTTGCCTGGCTA
GAACACCACTTGGGCGATGGCGAAGCGCTGGTGCCAGCGCGTTTCAGCCCGCAGGAATTGCCGCTGGTGGTGGTGCCCGA
TCGTGAGGCCGAGCTCAAACGGCGCCTGGAGCAGGACGAGAACGACAAGCGCGTCTCTACCGCCGCATTGCGGTTGGCGC
GTCAGTTCACCGCACGTATCGAAGCGCGGCAGACCCAGCGGCTGTATCTGAATCTCGATAATCCGGCGCTGCAGGCTTTG
CTGGCCGCGCAGCGCGCGGGCAATCCGCAGGCGGCGGTGGCGGCGCGCCTGCTGCGCTCGCTCAAGGTGATCGTCTCGGC
GCAAGGGCGCACGCAGCCGCAGCCGGGCAGCACCGAAGCGGGCGTTTCCGATCTGAACAAGGCCTTCGGTGATCTTGCAG
AGGCCGTGACCCAATTGCTGGCGCGCTGA

Upstream 100 bases:

>100_bases
TGCGTGCGAGGTGGCTTGCGTCTATCCTTTCCGGCTGGCACTGGCACCCAGGGGGCGCGTCCGAGGATGGGCGTCGTCGC
CAAGGAAACGACGACCGATC

Downstream 100 bases:

>100_bases
GCGCCGCATCGCAGGAGCGACACGATGGAAATCTGGAACTGGGTGGAAAAACTGCAGGACGATCTGGGTGAAGCCGGGCA
GCCGCAAAATGCGCAGCTGC

Product: Hsp90xo protein

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 622; Mature: 622

Protein sequence:

>622_residues
MQDPTPEATDAAQIRRAGVDLNGLMSVLSKHLYSTPVVALRELAQNAHDSILRRRLEQPDWQGESRVEVHADAAQGIVRI
VDTGAGLTQQEIHDYLATVGVGYTRGLRQGGHEDSGLIGMFGLGFLSAFVLARRVTVRTTSYQSPTLGHCYISSNAEQYT
VSPIPARAQVGTEVMLELHSDYLLLAQEGRLREILSRYCALLREPIWIGADSQPINPEPPPWRMHDAVPLHPVQAWRRQR
EFAARFERNFEPLCCMPVRVEEGSDAVGLLWVQDGATYGTSDNRNLSVFLRGMLLDDNARELLPPWAGFIGGVIESNRLT
PTASREDLQRDTVYSAVQHALSEALVQGLADVARQQPEAWRRILLRHNEALLGAALCDERLFELLLEHVRVPTSQGDLPA
QQLPARGAVHVILDSDSGFEEMLFRAMGVPVAYGNRYAVVPFLRRWAQAKGVRLVELGTEQGNRQLFHLDTLPADELAWL
EHHLGDGEALVPARFSPQELPLVVVPDREAELKRRLEQDENDKRVSTAALRLARQFTARIEARQTQRLYLNLDNPALQAL
LAAQRAGNPQAAVAARLLRSLKVIVSAQGRTQPQPGSTEAGVSDLNKAFGDLAEAVTQLLAR

Sequences:

>Translated_622_residues
MQDPTPEATDAAQIRRAGVDLNGLMSVLSKHLYSTPVVALRELAQNAHDSILRRRLEQPDWQGESRVEVHADAAQGIVRI
VDTGAGLTQQEIHDYLATVGVGYTRGLRQGGHEDSGLIGMFGLGFLSAFVLARRVTVRTTSYQSPTLGHCYISSNAEQYT
VSPIPARAQVGTEVMLELHSDYLLLAQEGRLREILSRYCALLREPIWIGADSQPINPEPPPWRMHDAVPLHPVQAWRRQR
EFAARFERNFEPLCCMPVRVEEGSDAVGLLWVQDGATYGTSDNRNLSVFLRGMLLDDNARELLPPWAGFIGGVIESNRLT
PTASREDLQRDTVYSAVQHALSEALVQGLADVARQQPEAWRRILLRHNEALLGAALCDERLFELLLEHVRVPTSQGDLPA
QQLPARGAVHVILDSDSGFEEMLFRAMGVPVAYGNRYAVVPFLRRWAQAKGVRLVELGTEQGNRQLFHLDTLPADELAWL
EHHLGDGEALVPARFSPQELPLVVVPDREAELKRRLEQDENDKRVSTAALRLARQFTARIEARQTQRLYLNLDNPALQAL
LAAQRAGNPQAAVAARLLRSLKVIVSAQGRTQPQPGSTEAGVSDLNKAFGDLAEAVTQLLAR
>Mature_622_residues
MQDPTPEATDAAQIRRAGVDLNGLMSVLSKHLYSTPVVALRELAQNAHDSILRRRLEQPDWQGESRVEVHADAAQGIVRI
VDTGAGLTQQEIHDYLATVGVGYTRGLRQGGHEDSGLIGMFGLGFLSAFVLARRVTVRTTSYQSPTLGHCYISSNAEQYT
VSPIPARAQVGTEVMLELHSDYLLLAQEGRLREILSRYCALLREPIWIGADSQPINPEPPPWRMHDAVPLHPVQAWRRQR
EFAARFERNFEPLCCMPVRVEEGSDAVGLLWVQDGATYGTSDNRNLSVFLRGMLLDDNARELLPPWAGFIGGVIESNRLT
PTASREDLQRDTVYSAVQHALSEALVQGLADVARQQPEAWRRILLRHNEALLGAALCDERLFELLLEHVRVPTSQGDLPA
QQLPARGAVHVILDSDSGFEEMLFRAMGVPVAYGNRYAVVPFLRRWAQAKGVRLVELGTEQGNRQLFHLDTLPADELAWL
EHHLGDGEALVPARFSPQELPLVVVPDREAELKRRLEQDENDKRVSTAALRLARQFTARIEARQTQRLYLNLDNPALQAL
LAAQRAGNPQAAVAARLLRSLKVIVSAQGRTQPQPGSTEAGVSDLNKAFGDLAEAVTQLLAR

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI155722983, Length=357, Percent_Identity=24.9299719887955, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI4507677, Length=408, Percent_Identity=22.7941176470588, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI153792590, Length=199, Percent_Identity=27.6381909547739, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI20149594, Length=196, Percent_Identity=28.0612244897959, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI154146191, Length=199, Percent_Identity=27.6381909547739, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI1786679, Length=367, Percent_Identity=28.8828337874659, Blast_Score=138, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI115535205, Length=365, Percent_Identity=22.7397260273973, Blast_Score=105, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI115535167, Length=365, Percent_Identity=22.7397260273973, Blast_Score=105, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17559162, Length=438, Percent_Identity=22.1461187214612, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17542208, Length=369, Percent_Identity=23.3062330623306, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6323840, Length=401, Percent_Identity=21.9451371571072, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6325016, Length=206, Percent_Identity=26.6990291262136, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24586016, Length=360, Percent_Identity=24.7222222222222, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI21357739, Length=387, Percent_Identity=23.7726098191214, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17647529, Length=192, Percent_Identity=28.125, Blast_Score=82, Evalue=9e-16,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 68920; Mature: 68920

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDPTPEATDAAQIRRAGVDLNGLMSVLSKHLYSTPVVALRELAQNAHDSILRRRLEQPD
CCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
WQGESRVEVHADAAQGIVRIVDTGAGLTQQEIHDYLATVGVGYTRGLRQGGHEDSGLIGM
CCCCCEEEEECHHHHCCEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCCCHHH
FGLGFLSAFVLARRVTVRTTSYQSPTLGHCYISSNAEQYTVSPIPARAQVGTEVMLELHS
HHHHHHHHHHHHHHHHEEECCCCCCCCEEEEECCCCCEEEECCCCCHHHHHHHHHHHHCC
DYLLLAQEGRLREILSRYCALLREPIWIGADSQPINPEPPPWRMHDAVPLHPVQAWRRQR
CEEEEECCCHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
EFAARFERNFEPLCCMPVRVEEGSDAVGLLWVQDGATYGTSDNRNLSVFLRGMLLDDNAR
HHHHHHHCCCCCEEEEEEEECCCCCEEEEEEEECCCEECCCCCCCEEEEEEEEEECCCCH
ELLPPWAGFIGGVIESNRLTPTASREDLQRDTVYSAVQHALSEALVQGLADVARQQPEAW
HHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
RRILLRHNEALLGAALCDERLFELLLEHVRVPTSQGDLPAQQLPARGAVHVILDSDSGFE
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCEEEEEECCCCHH
EMLFRAMGVPVAYGNRYAVVPFLRRWAQAKGVRLVELGTEQGNRQLFHLDTLPADELAWL
HHHHHHHCCCEEECCCEEHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCHHHHHHH
EHHLGDGEALVPARFSPQELPLVVVPDREAELKRRLEQDENDKRVSTAALRLARQFTARI
HHHCCCCCEECCCCCCCCCCCEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
EARQTQRLYLNLDNPALQALLAAQRAGNPQAAVAARLLRSLKVIVSAQGRTQPQPGSTEA
HHHCCEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
GVSDLNKAFGDLAEAVTQLLAR
CHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQDPTPEATDAAQIRRAGVDLNGLMSVLSKHLYSTPVVALRELAQNAHDSILRRRLEQPD
CCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
WQGESRVEVHADAAQGIVRIVDTGAGLTQQEIHDYLATVGVGYTRGLRQGGHEDSGLIGM
CCCCCEEEEECHHHHCCEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCCCHHH
FGLGFLSAFVLARRVTVRTTSYQSPTLGHCYISSNAEQYTVSPIPARAQVGTEVMLELHS
HHHHHHHHHHHHHHHHEEECCCCCCCCEEEEECCCCCEEEECCCCCHHHHHHHHHHHHCC
DYLLLAQEGRLREILSRYCALLREPIWIGADSQPINPEPPPWRMHDAVPLHPVQAWRRQR
CEEEEECCCHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
EFAARFERNFEPLCCMPVRVEEGSDAVGLLWVQDGATYGTSDNRNLSVFLRGMLLDDNAR
HHHHHHHCCCCCEEEEEEEECCCCCEEEEEEEECCCEECCCCCCCEEEEEEEEEECCCCH
ELLPPWAGFIGGVIESNRLTPTASREDLQRDTVYSAVQHALSEALVQGLADVARQQPEAW
HHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
RRILLRHNEALLGAALCDERLFELLLEHVRVPTSQGDLPAQQLPARGAVHVILDSDSGFE
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCEEEEEECCCCHH
EMLFRAMGVPVAYGNRYAVVPFLRRWAQAKGVRLVELGTEQGNRQLFHLDTLPADELAWL
HHHHHHHCCCEEECCCEEHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCHHHHHHH
EHHLGDGEALVPARFSPQELPLVVVPDREAELKRRLEQDENDKRVSTAALRLARQFTARI
HHHCCCCCEECCCCCCCCCCCEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
EARQTQRLYLNLDNPALQALLAAQRAGNPQAAVAARLLRSLKVIVSAQGRTQPQPGSTEA
HHHCCEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
GVSDLNKAFGDLAEAVTQLLAR
CHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]