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The map label for this gene is ffh [H]

Identifier: 84622872

GI number: 84622872

Start: 1324132

End: 1325508

Strand: Direct

Name: ffh [H]

Synonym: XOO_1215

Alternate gene names: 84622872

Gene position: 1324132-1325508 (Clockwise)

Preceding gene: 84622871

Following gene: 84622873

Centisome position: 26.8

GC content: 64.85

Gene sequence:

>1377_bases
ATGTTCGAGTCCCTTACCCAACGTCTCTCCGGCACCATGGAGCGCCTGCGCGGCCGCGGCCGCCTGACCGAGGAGAACAT
CCGCGAAGCCACCCGTGAAGTGCGCATCGCGCTGCTCGAAGCCGACGTCGCGCTGCCGGTGGTGCAGGCGCTGATCGAGC
GCATCAAGGTGCGGGCTGTCGGCCAGGAAGTACTCAAGTCGCTCACCCCGGGCCAGGCGCTGATCAAAATCGTGCGCGAC
GAGCTCACTGCCGTCATGGGCGCCGCCGCTGCCGACGTCAATCTCAACGTGCCGGCCCCGGCAATCGTCCTGATGGCCGG
CCTGCAGGGTGCGGGCAAGACCACCACGGTCGGCAAGCTCGCCAAGCACCTGAAGGAAAAGCGCAAGAAAAAGGTCATGG
TGGTCTCGGCCGACGTCTACCGCCCGGCCGCGATCGAGCAGCTCAAGACCCTGGCCGAACAGGTCGGCGTGCTGTTCTTC
GCCTCCGACGCCTCGCAGAAGCCCGTCGACATCGTGCGCGCGGCCATCAGCGATGCGCGCAAGTCGTTCGTCGACGTGCT
GCTGGTCGATACCGCCGGCCGTCTGGCGATCGATCAGGTAATGATGGACGAGATCAAGGCGCTGCACGCCGCGGTCAACC
CCACCGAAACCCTGTTCGTGGTCGATGCGATGACCGGTCAGGATGCGGCCAACACCGCCAAGGCCTTCGGCGAGGCGCTG
CCGCTGACCGGCGTGGTGCTGACCAAGACCGACGGCGACGCCCGCGGCGGTGCCGCGCTGAGCGTGCGCTATATCACCGG
CAAGCCGATCAAGTTCGTCGGTACCGGCGAAAAGACCGACGGCCTGGATGTGTTCCATCCGGATCGCGTCGCCAGCCGTA
TTCTGGACATGGGCGACGTGCTGTCGCTGGTGGAGCAGGTCGAGCACAGCGTCGATCAGGAAAAGGCCGCCAAACTGGCC
GCCAAGGTCGCCAAGGGCAAGAAGTTCGACCTCAACGACATGAAAGAGCAGCTCGAGCAAATGCAGAACATGGGCGGCAT
CCATGGGCTGATGGACAAGCTGCCGGGCATGGGTCAGATCTCGGATAACGTGAAGCAGCAGGTCACCGGCAAGGAAGTGC
CGCGCATGATCGCCATCATCAACTCGATGACCAAGAAAGAGCGCCGCAACCCGACCCTGCTCAACGGCTCGCGCCGCGCA
CGCATCGCCCGCGGCTCGGGCATGCAGCCGGCCGACGTCAACAAGCTGATGAAGCAGTACCAGCAGATGGAAAAGATGAT
GGGCAAGCTGGCCGGCGGCGGCATGAAGGGCCTGATGCGCAATATGAAGGGCATGATGGGCGCCATGGGCGGCCGTGGCG
GCATGCCTTTCCGCTGA

Upstream 100 bases:

>100_bases
TTCCTCACGGGCTACGTCGCCGTGCCGGGGCAGACTGGGGCGGGCCGCCAGCCGGTGCCGCTATAATCGGCACCTGTTTC
CCCTCTGCGGTCCTATGCGC

Downstream 100 bases:

>100_bases
GCAACCTGCGCAAGCCGCGCGTGCCGTGAAGACATCCGCAGGCGCGCACTGCGTGCATGTTGCGCTGGCCCTTGTGCTGG
CATGGCAGGCCACGTCGGGG

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MFESLTQRLSGTMERLRGRGRLTEENIREATREVRIALLEADVALPVVQALIERIKVRAVGQEVLKSLTPGQALIKIVRD
ELTAVMGAAAADVNLNVPAPAIVLMAGLQGAGKTTTVGKLAKHLKEKRKKKVMVVSADVYRPAAIEQLKTLAEQVGVLFF
ASDASQKPVDIVRAAISDARKSFVDVLLVDTAGRLAIDQVMMDEIKALHAAVNPTETLFVVDAMTGQDAANTAKAFGEAL
PLTGVVLTKTDGDARGGAALSVRYITGKPIKFVGTGEKTDGLDVFHPDRVASRILDMGDVLSLVEQVEHSVDQEKAAKLA
AKVAKGKKFDLNDMKEQLEQMQNMGGIHGLMDKLPGMGQISDNVKQQVTGKEVPRMIAIINSMTKKERRNPTLLNGSRRA
RIARGSGMQPADVNKLMKQYQQMEKMMGKLAGGGMKGLMRNMKGMMGAMGGRGGMPFR

Sequences:

>Translated_458_residues
MFESLTQRLSGTMERLRGRGRLTEENIREATREVRIALLEADVALPVVQALIERIKVRAVGQEVLKSLTPGQALIKIVRD
ELTAVMGAAAADVNLNVPAPAIVLMAGLQGAGKTTTVGKLAKHLKEKRKKKVMVVSADVYRPAAIEQLKTLAEQVGVLFF
ASDASQKPVDIVRAAISDARKSFVDVLLVDTAGRLAIDQVMMDEIKALHAAVNPTETLFVVDAMTGQDAANTAKAFGEAL
PLTGVVLTKTDGDARGGAALSVRYITGKPIKFVGTGEKTDGLDVFHPDRVASRILDMGDVLSLVEQVEHSVDQEKAAKLA
AKVAKGKKFDLNDMKEQLEQMQNMGGIHGLMDKLPGMGQISDNVKQQVTGKEVPRMIAIINSMTKKERRNPTLLNGSRRA
RIARGSGMQPADVNKLMKQYQQMEKMMGKLAGGGMKGLMRNMKGMMGAMGGRGGMPFR
>Mature_458_residues
MFESLTQRLSGTMERLRGRGRLTEENIREATREVRIALLEADVALPVVQALIERIKVRAVGQEVLKSLTPGQALIKIVRD
ELTAVMGAAAADVNLNVPAPAIVLMAGLQGAGKTTTVGKLAKHLKEKRKKKVMVVSADVYRPAAIEQLKTLAEQVGVLFF
ASDASQKPVDIVRAAISDARKSFVDVLLVDTAGRLAIDQVMMDEIKALHAAVNPTETLFVVDAMTGQDAANTAKAFGEAL
PLTGVVLTKTDGDARGGAALSVRYITGKPIKFVGTGEKTDGLDVFHPDRVASRILDMGDVLSLVEQVEHSVDQEKAAKLA
AKVAKGKKFDLNDMKEQLEQMQNMGGIHGLMDKLPGMGQISDNVKQQVTGKEVPRMIAIINSMTKKERRNPTLLNGSRRA
RIARGSGMQPADVNKLMKQYQQMEKMMGKLAGGGMKGLMRNMKGMMGAMGGRGGMPFR

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=448, Percent_Identity=30.1339285714286, Blast_Score=203, Evalue=3e-52,
Organism=Homo sapiens, GI226371618, Length=351, Percent_Identity=32.1937321937322, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI23308697, Length=304, Percent_Identity=28.9473684210526, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI295424842, Length=304, Percent_Identity=28.9473684210526, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI89061728, Length=140, Percent_Identity=34.2857142857143, Blast_Score=92, Evalue=8e-19,
Organism=Escherichia coli, GI1788963, Length=446, Percent_Identity=68.1614349775785, Blast_Score=590, Evalue=1e-170,
Organism=Escherichia coli, GI1789874, Length=229, Percent_Identity=36.2445414847162, Blast_Score=147, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17539958, Length=419, Percent_Identity=29.8329355608592, Blast_Score=205, Evalue=5e-53,
Organism=Caenorhabditis elegans, GI193206261, Length=242, Percent_Identity=33.0578512396694, Blast_Score=105, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6325345, Length=441, Percent_Identity=33.1065759637188, Blast_Score=216, Evalue=5e-57,
Organism=Saccharomyces cerevisiae, GI6320498, Length=208, Percent_Identity=29.3269230769231, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI17647949, Length=442, Percent_Identity=30.7692307692308, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24641198, Length=261, Percent_Identity=29.1187739463602, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 49406; Mature: 49406

Theoretical pI: Translated: 10.54; Mature: 10.54

Prosite motif: PS00589 PTS_HPR_SER ; PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFESLTQRLSGTMERLRGRGRLTEENIREATREVRIALLEADVALPVVQALIERIKVRAV
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQEVLKSLTPGQALIKIVRDELTAVMGAAAADVNLNVPAPAIVLMAGLQGAGKTTTVGKL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCHHHHHH
AKHLKEKRKKKVMVVSADVYRPAAIEQLKTLAEQVGVLFFASDASQKPVDIVRAAISDAR
HHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHH
KSFVDVLLVDTAGRLAIDQVMMDEIKALHAAVNPTETLFVVDAMTGQDAANTAKAFGEAL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHC
PLTGVVLTKTDGDARGGAALSVRYITGKPIKFVGTGEKTDGLDVFHPDRVASRILDMGDV
CCCCEEEEECCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
LSLVEQVEHSVDQEKAAKLAAKVAKGKKFDLNDMKEQLEQMQNMGGIHGLMDKLPGMGQI
HHHHHHHHHHHCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCH
SDNVKQQVTGKEVPRMIAIINSMTKKERRNPTLLNGSRRARIARGSGMQPADVNKLMKQY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHEEECCCCCCCHHHHHHHHHH
QQMEKMMGKLAGGGMKGLMRNMKGMMGAMGGRGGMPFR
HHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MFESLTQRLSGTMERLRGRGRLTEENIREATREVRIALLEADVALPVVQALIERIKVRAV
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQEVLKSLTPGQALIKIVRDELTAVMGAAAADVNLNVPAPAIVLMAGLQGAGKTTTVGKL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCHHHHHH
AKHLKEKRKKKVMVVSADVYRPAAIEQLKTLAEQVGVLFFASDASQKPVDIVRAAISDAR
HHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHH
KSFVDVLLVDTAGRLAIDQVMMDEIKALHAAVNPTETLFVVDAMTGQDAANTAKAFGEAL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHC
PLTGVVLTKTDGDARGGAALSVRYITGKPIKFVGTGEKTDGLDVFHPDRVASRILDMGDV
CCCCEEEEECCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
LSLVEQVEHSVDQEKAAKLAAKVAKGKKFDLNDMKEQLEQMQNMGGIHGLMDKLPGMGQI
HHHHHHHHHHHCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCH
SDNVKQQVTGKEVPRMIAIINSMTKKERRNPTLLNGSRRARIARGSGMQPADVNKLMKQY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHEEECCCCCCCHHHHHHHHHH
QQMEKMMGKLAGGGMKGLMRNMKGMMGAMGGRGGMPFR
HHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]