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The map label for this gene is murA [H]

Identifier: 84622847

GI number: 84622847

Start: 1297715

End: 1298989

Strand: Direct

Name: murA [H]

Synonym: XOO_1190

Alternate gene names: 84622847

Gene position: 1297715-1298989 (Clockwise)

Preceding gene: 84622846

Following gene: 84622848

Centisome position: 26.27

GC content: 66.98

Gene sequence:

>1275_bases
ATGGCAAAAATCGTAGTGACCGGCGGCCAAGCGCTGCAGGGCGAAGTCAATATTTCCGGTGCCAAGAACGCAGTGCTGCC
GATCCTGTGCGCGACCCTGCTGGCCGACGCGCCGGTGCAGATCAGCAACGTGCCGCATCTGCACGACGTGATCACCATGG
TGAAATTGCTCAGCGAGCTGGGTGCCGAAGTCACCATCGACGAAGGCACGCTGGCCAAGGGCCGTTCGATCCTGGTCGAC
CCGCGCTCGGTCACGCATCAGATCGCGCCGTACGAGCTGGTCAAGACCATGCGCGCCTCGATCCTGGTGCTGGGCCCGCT
GCTGGCGCGCTACGGCACCGCCGAAGTGTCGCTGCCCGGCGGCTGCGCGATCGGCTCGCGCCCGGTGGATCAGCACATCA
AGGGCCTGCAGGCGCTGGGTGCCGAGATCAGCGTGGAGAACGGCTACATCAAGGCCACCAGCCACGGGCGCCTGAAGGGC
GGCCGCTACGTGTTCGACATGGTCAGCGTCACCGGCACCGAGAACGTGCTGATGGCCGCGGTGCTGGCCGAGGGCACCAC
GGTGCTGGAAAACGCGGCGATGGAGCCGGAAGTCACCGACCTGGCCGACTGCATGATCGCACTTGGCGCGCAGATCGAAG
GTGCCGGAACCCCGCGCATCGTGGTGCAGGGCGTGCAGCGTCTGGGCGGCGGGCACCATGCGGTGCTGCCGGATCGCATC
GAAACCGGCACCTTCCTGGTCGCTGCGGCGATGACCGGCGGCAGCGTCACCGTGCGCCGCGCCCGCCCGGAAACCCTGGA
TGCAATGCTGGACAAGCTCACCGAAGCCGGCGCCACCATCACCACCACCGCCGACAGCATCACGCTGGACATGCAGGGCA
AGCGCCCGCGCGCAGTCAGCCTGACCACCGCGCCGTACCCGGCGTTTCCCACCGATATGCAGGCGCAATTCATGGCGCTC
AACTGCGTGGCAGACGGCGTGGGCGTGATCAACGAAACCATCTTCGAAAACCGCTTCATGCACGTCAACGAGCTGCTGCG
CCTGGGCGCGGACATCCAGGTCGAAGGCCACACTGCCATCGTGCGTGGTGCCGCACGCCTGAGCGGCGCGCCGGTGATGG
CCACCGACCTGCGCGCATCGGCGTCGCTGATCCTGGCTGGCCTGGTGGCCGATGGCGACACCACCATCGACCGCATCTAC
CACCTGGACCGTGGTTACGAAAACATCGAGGAGAAGCTGGGGGCGCTGGGCGCGACCATCCAGCGCACCGCATGA

Upstream 100 bases:

>100_bases
CGATCTGTGCGCCTCAGCGCCACGCCGTTTGCACTGAGGCCGAAACGCTCGCACGTCATTCCCCGCCACACCTTCTCTTT
TCGGATTTCTTAAGATTCCC

Downstream 100 bases:

>100_bases
TCCTGCGCGGACGTTTCACTACCCGGCGCAAGATCCTGCTCGGGGTCATCGTGCTGATCCTGGCGTGGCTGGCCTATGCC
TGGAGCGTGGGCATGGCCAT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MAKIVVTGGQALQGEVNISGAKNAVLPILCATLLADAPVQISNVPHLHDVITMVKLLSELGAEVTIDEGTLAKGRSILVD
PRSVTHQIAPYELVKTMRASILVLGPLLARYGTAEVSLPGGCAIGSRPVDQHIKGLQALGAEISVENGYIKATSHGRLKG
GRYVFDMVSVTGTENVLMAAVLAEGTTVLENAAMEPEVTDLADCMIALGAQIEGAGTPRIVVQGVQRLGGGHHAVLPDRI
ETGTFLVAAAMTGGSVTVRRARPETLDAMLDKLTEAGATITTTADSITLDMQGKRPRAVSLTTAPYPAFPTDMQAQFMAL
NCVADGVGVINETIFENRFMHVNELLRLGADIQVEGHTAIVRGAARLSGAPVMATDLRASASLILAGLVADGDTTIDRIY
HLDRGYENIEEKLGALGATIQRTA

Sequences:

>Translated_424_residues
MAKIVVTGGQALQGEVNISGAKNAVLPILCATLLADAPVQISNVPHLHDVITMVKLLSELGAEVTIDEGTLAKGRSILVD
PRSVTHQIAPYELVKTMRASILVLGPLLARYGTAEVSLPGGCAIGSRPVDQHIKGLQALGAEISVENGYIKATSHGRLKG
GRYVFDMVSVTGTENVLMAAVLAEGTTVLENAAMEPEVTDLADCMIALGAQIEGAGTPRIVVQGVQRLGGGHHAVLPDRI
ETGTFLVAAAMTGGSVTVRRARPETLDAMLDKLTEAGATITTTADSITLDMQGKRPRAVSLTTAPYPAFPTDMQAQFMAL
NCVADGVGVINETIFENRFMHVNELLRLGADIQVEGHTAIVRGAARLSGAPVMATDLRASASLILAGLVADGDTTIDRIY
HLDRGYENIEEKLGALGATIQRTA
>Mature_423_residues
AKIVVTGGQALQGEVNISGAKNAVLPILCATLLADAPVQISNVPHLHDVITMVKLLSELGAEVTIDEGTLAKGRSILVDP
RSVTHQIAPYELVKTMRASILVLGPLLARYGTAEVSLPGGCAIGSRPVDQHIKGLQALGAEISVENGYIKATSHGRLKGG
RYVFDMVSVTGTENVLMAAVLAEGTTVLENAAMEPEVTDLADCMIALGAQIEGAGTPRIVVQGVQRLGGGHHAVLPDRIE
TGTFLVAAAMTGGSVTVRRARPETLDAMLDKLTEAGATITTTADSITLDMQGKRPRAVSLTTAPYPAFPTDMQAQFMALN
CVADGVGVINETIFENRFMHVNELLRLGADIQVEGHTAIVRGAARLSGAPVMATDLRASASLILAGLVADGDTTIDRIYH
LDRGYENIEEKLGALGATIQRTA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=422, Percent_Identity=61.8483412322275, Blast_Score=515, Evalue=1e-147,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 44421; Mature: 44290

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKIVVTGGQALQGEVNISGAKNAVLPILCATLLADAPVQISNVPHLHDVITMVKLLSEL
CEEEEEECCCEEECEEEECCCCCHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHC
GAEVTIDEGTLAKGRSILVDPRSVTHQIAPYELVKTMRASILVLGPLLARYGTAEVSLPG
CCEEEECCCCCCCCCEEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCC
GCAIGSRPVDQHIKGLQALGAEISVENGYIKATSHGRLKGGRYVFDMVSVTGTENVLMAA
CCCCCCCCHHHHHHHHHHCCCEEEECCCEEEECCCCCCCCCEEEEEEEEECCCCHHHHHH
VLAEGTTVLENAAMEPEVTDLADCMIALGAQIEGAGTPRIVVQGVQRLGGGHHAVLPDRI
HHHCCCHHHHHCCCCCCHHHHHHHHHHHCCEECCCCCCHHHHHHHHHHCCCCEEECCCCC
ETGTFLVAAAMTGGSVTVRRARPETLDAMLDKLTEAGATITTTADSITLDMQGKRPRAVS
CCCCEEEEEEECCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCEEEEEECCCCCCEEE
LTTAPYPAFPTDMQAQFMALNCVADGVGVINETIFENRFMHVNELLRLGADIQVEGHTAI
EECCCCCCCCCCCHHHHEEEHHHHCCHHHHHHHHHHCCCHHHHHHHHCCCCEEECCCCEE
VRGAARLSGAPVMATDLRASASLILAGLVADGDTTIDRIYHLDRGYENIEEKLGALGATI
EEHHHHHCCCCEEEHHHHHHHHEEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHCCHH
QRTA
CCCC
>Mature Secondary Structure 
AKIVVTGGQALQGEVNISGAKNAVLPILCATLLADAPVQISNVPHLHDVITMVKLLSEL
EEEEEECCCEEECEEEECCCCCHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHC
GAEVTIDEGTLAKGRSILVDPRSVTHQIAPYELVKTMRASILVLGPLLARYGTAEVSLPG
CCEEEECCCCCCCCCEEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCC
GCAIGSRPVDQHIKGLQALGAEISVENGYIKATSHGRLKGGRYVFDMVSVTGTENVLMAA
CCCCCCCCHHHHHHHHHHCCCEEEECCCEEEECCCCCCCCCEEEEEEEEECCCCHHHHHH
VLAEGTTVLENAAMEPEVTDLADCMIALGAQIEGAGTPRIVVQGVQRLGGGHHAVLPDRI
HHHCCCHHHHHCCCCCCHHHHHHHHHHHCCEECCCCCCHHHHHHHHHHCCCCEEECCCCC
ETGTFLVAAAMTGGSVTVRRARPETLDAMLDKLTEAGATITTTADSITLDMQGKRPRAVS
CCCCEEEEEEECCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCEEEEEECCCCCCEEE
LTTAPYPAFPTDMQAQFMALNCVADGVGVINETIFENRFMHVNELLRLGADIQVEGHTAI
EECCCCCCCCCCCHHHHEEEHHHHCCHHHHHHHHHHCCCHHHHHHHHCCCCEEECCCCEE
VRGAARLSGAPVMATDLRASASLILAGLVADGDTTIDRIYHLDRGYENIEEKLGALGATI
EEHHHHHCCCCEEEHHHHHHHHEEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHCCHH
QRTA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]