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The map label for this gene is fucP [H]

Identifier: 84621968

GI number: 84621968

Start: 339152

End: 340453

Strand: Direct

Name: fucP [H]

Synonym: XOO_0311

Alternate gene names: 84621968

Gene position: 339152-340453 (Clockwise)

Preceding gene: 84621965

Following gene: 84621969

Centisome position: 6.87

GC content: 63.13

Gene sequence:

>1302_bases
ATGCATCAAAGTGACATTGCCGCGTCACCGCGCGGCAACCTGGCGCGTACCGCCATGGTTCCCCTGTTGTTGGTCGTCAG
CCTGTTCTTTTTATGGGGCATGGCCAACAACCTCAACGACATCCTGATCAAGCAGTTCAAGAAGGCCTTCGAACTGACCG
ACCTGCAGGCCGGGCTGGTGCAGAGCGCCTTCTACATGGGCTATTTCATGTTTGCGATGCCGGCGGCGATGTTCATGCGC
CGCTACAGCTACAAGGCGGCGGCGGTGCTGGGCCTGCTGCTGTACGCGTGCGGCGCGTTCGTGTTCTATCCGGCCGCGCA
GGTGCACACCTACTGGCTGTTCCTGCTGGCCTTGTTCGTGATCGCCAGCGGGCTGGCGTTTCTGGAAACCACTGCCAACC
CGCTGGTGACCGTGCTTGGCCCAGCCGATGGCGCGGCACGGCGTTTGAACCTGGCGCAGGCGTTTAACCCGTTGGGGTCG
ATCACCGGGGTGCTGGTCGGTCAGCACTTCATCTTCTCCGGCGTGGAACGCACCCCAGCCGAGTTGGCGGCAATGGCGCC
GGCCGCGCGCGAGGCGTTCTTCGCCACCGAATCGTCGGCCGTGCAGATGCCATACCTGATCATCGGTGCGGTGGTGGTGC
TGTGGGCGATCCTGATTGCGCTGGTGCGCTTTCCCACCAGCGCGCCGGATGCCGATGCCGGCGTGGCGCCAAAGCGCGCA
CGTTTCAGTGAATTGCTGGGTAACCGCTTGTTCGTATTTTCGGTGGTGGCGCAGTTCTTTTACGTGGGCGCGCAGGTCGG
CATCTGGAGCTATCTGATCCGCTATCTGCAGGATGCGGTGCCCGGCACGCCGGAAAAAACCGCGGCCACGTATCTGACCA
TCTCGTTGGTGTTGTTCATGGCCGGCCGCTTCATCGGCACCGCGCTGCTGCGCTATCTGGCGCCGGCCAAGCTGCTAGCC
AGTTTTGCGGTGATCAATCTGATCTTGTGCGCGGTGGCCATCGCGCTGCCTGGCTGGACCGGGTTGTATGCGCTGGTGGC
AGCCAGCGTGTTTATGTCGGTGATGTTCCCGACCATTTTTGCGCTGGGCCTGGACGGCATGCATGACGATGCCCGCAAGC
TGGGGTCGTCCCTGCTGGTGATGTCCATCATCGGCGGGGCGTTGCTCACTGCGGTGATGGGCGCGGTATCCGACATGGCC
GGCATCCACTGGGCATTGGTGGTGCCGGGTGCGTGCTTTGCGGTGATCTTGTTGTTTGCGTTGCGCGCACGCCGCGCGGC
GCCCGTGATTGCAGGAGCCTGA

Upstream 100 bases:

>100_bases
AAATATAAACAAAGATTTTATATTTGCATGGAGCTGGCCTGCGCAGTACGCTCGCCCGATTGCAAAGCAAGCGCCACAGC
CTTGGGAGGGGAACGGTCGC

Downstream 100 bases:

>100_bases
GCATGCCGCGTCTTTGTTATGTGCTGGATCTACACGACGATGCGGCGTTGATCGCCGAATACGAGCGTTGGCATCAGCCC
ACCGAGGTATGGCCGGAAGT

Product: fucose permease

Products: Proton [Cytoplasm]; L-fucose [Cytoplasm] [C]

Alternate protein names: 6-deoxy-L-galactose permease; L-fucose permease [H]

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MHQSDIAASPRGNLARTAMVPLLLVVSLFFLWGMANNLNDILIKQFKKAFELTDLQAGLVQSAFYMGYFMFAMPAAMFMR
RYSYKAAAVLGLLLYACGAFVFYPAAQVHTYWLFLLALFVIASGLAFLETTANPLVTVLGPADGAARRLNLAQAFNPLGS
ITGVLVGQHFIFSGVERTPAELAAMAPAAREAFFATESSAVQMPYLIIGAVVVLWAILIALVRFPTSAPDADAGVAPKRA
RFSELLGNRLFVFSVVAQFFYVGAQVGIWSYLIRYLQDAVPGTPEKTAATYLTISLVLFMAGRFIGTALLRYLAPAKLLA
SFAVINLILCAVAIALPGWTGLYALVAASVFMSVMFPTIFALGLDGMHDDARKLGSSLLVMSIIGGALLTAVMGAVSDMA
GIHWALVVPGACFAVILLFALRARRAAPVIAGA

Sequences:

>Translated_433_residues
MHQSDIAASPRGNLARTAMVPLLLVVSLFFLWGMANNLNDILIKQFKKAFELTDLQAGLVQSAFYMGYFMFAMPAAMFMR
RYSYKAAAVLGLLLYACGAFVFYPAAQVHTYWLFLLALFVIASGLAFLETTANPLVTVLGPADGAARRLNLAQAFNPLGS
ITGVLVGQHFIFSGVERTPAELAAMAPAAREAFFATESSAVQMPYLIIGAVVVLWAILIALVRFPTSAPDADAGVAPKRA
RFSELLGNRLFVFSVVAQFFYVGAQVGIWSYLIRYLQDAVPGTPEKTAATYLTISLVLFMAGRFIGTALLRYLAPAKLLA
SFAVINLILCAVAIALPGWTGLYALVAASVFMSVMFPTIFALGLDGMHDDARKLGSSLLVMSIIGGALLTAVMGAVSDMA
GIHWALVVPGACFAVILLFALRARRAAPVIAGA
>Mature_433_residues
MHQSDIAASPRGNLARTAMVPLLLVVSLFFLWGMANNLNDILIKQFKKAFELTDLQAGLVQSAFYMGYFMFAMPAAMFMR
RYSYKAAAVLGLLLYACGAFVFYPAAQVHTYWLFLLALFVIASGLAFLETTANPLVTVLGPADGAARRLNLAQAFNPLGS
ITGVLVGQHFIFSGVERTPAELAAMAPAAREAFFATESSAVQMPYLIIGAVVVLWAILIALVRFPTSAPDADAGVAPKRA
RFSELLGNRLFVFSVVAQFFYVGAQVGIWSYLIRYLQDAVPGTPEKTAATYLTISLVLFMAGRFIGTALLRYLAPAKLLA
SFAVINLILCAVAIALPGWTGLYALVAASVFMSVMFPTIFALGLDGMHDDARKLGSSLLVMSIIGGALLTAVMGAVSDMA
GIHWALVVPGACFAVILLFALRARRAAPVIAGA

Specific function: Mediates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell (symport system). Can also transport L-galactose and D-arabinose, but at reduced rates compared with L-fucose. Is not able to transport L-

COG id: COG0738

COG function: function code G; Fucose permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family [H]

Homologues:

Organism=Escherichia coli, GI1789166, Length=429, Percent_Identity=48.2517482517483, Blast_Score=366, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005275
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46262; Mature: 46262

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHQSDIAASPRGNLARTAMVPLLLVVSLFFLWGMANNLNDILIKQFKKAFELTDLQAGLV
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
QSAFYMGYFMFAMPAAMFMRRYSYKAAAVLGLLLYACGAFVFYPAAQVHTYWLFLLALFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IASGLAFLETTANPLVTVLGPADGAARRLNLAQAFNPLGSITGVLVGQHFIFSGVERTPA
HHCCHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCHH
ELAAMAPAAREAFFATESSAVQMPYLIIGAVVVLWAILIALVRFPTSAPDADAGVAPKRA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
RFSELLGNRLFVFSVVAQFFYVGAQVGIWSYLIRYLQDAVPGTPEKTAATYLTISLVLFM
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
AGRFIGTALLRYLAPAKLLASFAVINLILCAVAIALPGWTGLYALVAASVFMSVMFPTIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
ALGLDGMHDDARKLGSSLLVMSIIGGALLTAVMGAVSDMAGIHWALVVPGACFAVILLFA
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRARRAAPVIAGA
HHHHHCCCCCCCC
>Mature Secondary Structure
MHQSDIAASPRGNLARTAMVPLLLVVSLFFLWGMANNLNDILIKQFKKAFELTDLQAGLV
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
QSAFYMGYFMFAMPAAMFMRRYSYKAAAVLGLLLYACGAFVFYPAAQVHTYWLFLLALFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IASGLAFLETTANPLVTVLGPADGAARRLNLAQAFNPLGSITGVLVGQHFIFSGVERTPA
HHCCHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCHH
ELAAMAPAAREAFFATESSAVQMPYLIIGAVVVLWAILIALVRFPTSAPDADAGVAPKRA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
RFSELLGNRLFVFSVVAQFFYVGAQVGIWSYLIRYLQDAVPGTPEKTAATYLTISLVLFM
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
AGRFIGTALLRYLAPAKLLASFAVINLILCAVAIALPGWTGLYALVAASVFMSVMFPTIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
ALGLDGMHDDARKLGSSLLVMSIIGGALLTAVMGAVSDMAGIHWALVVPGACFAVILLFA
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRARRAAPVIAGA
HHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-fucose [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-fucose [Periplasm] = Proton [Cytoplasm] + L-fucose [Cytoplasm] [C]

General reaction: Permease [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2664711; 9278503; 2553671; 8052131; 2829831; 7783647 [H]