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The map label for this gene is dnaA

Identifier: 84621658

GI number: 84621658

Start: 41

End: 1369

Strand: Direct

Name: dnaA

Synonym: XOO_0001

Alternate gene names: 84621658

Gene position: 41-1369 (Clockwise)

Preceding gene: NA

Following gene: 84621659

Centisome position: 0.0

GC content: 64.64

Gene sequence:

>1329_bases
ATGGATGCTTGGCCCCGCTGTCTGGAACGTCTCGAAGCTGAATTCCCGCCCGAAGATGTCCACACCTGGTTGAAACCCCT
GCAAGCCGAAGACCGCGGCGACAGCATCGTGCTGTACGCCCCGAATGCCTTCATTGTCGACCAGGTCCGCGAACGCTACC
TGCCGCGCATCCGCGAGTTGCTGGCGTATTTTGCCGGCAATGGCGAAGTGGCGCTGGCCGTGGGGTCGCGTCCACGTGCG
CCCGAGCCGGCTCCGGCACCCGTCGCGGCGACCATTGCGCCGCAGGCTGCGCCGATCGCGCCGTTCGCCGGCAACCTGGA
TTCGCATTACACCTTCGCCAACTTCGTGGAAGGCCGCAGCAACCAGCTGGGTCTGGCCGCCGCGATCCAGGCCGCGCAGA
AGCCCGGCGACCGGGCGCACAACCCGTTGCTGTTGTACGGCAGCACCGGCCTGGGCAAGACCCACCTGATGTTCGCGGCG
GGCAATGCACTGCGGCAAGCCAAACCGGCTGCCAAGGTGATGTACCTGCGTTCGGAACAGTTCTTCAGCGCGATGATCCG
GGCGCTGCAGGACAAGGCGATGGATCAGTTCAAGCGCCAGTTCCAGCAGATTGATGCGTTGCTGATCGACGACATCCAGT
TCTTCGCGGGCAAGGACCGTACGCAGGAAGAGTTCTTCCACACCTTCAACGCGCTGTTCGATGGCCGCCAGCAGATCATC
CTGACCTGCGACCGCTACCCGCGCGAAGTGGAGGGCTTGGAGCCGCGGTTGAAGTCGCGCTTGGCCTGGGGCTTGTCGGT
CGCGATCGATCCGCCGGATTTCGAAACCCGTGCAGCCATCGTGCTGGCCAAGGCACGCGAGCGTGGCGCCGAGATTCCCG
ACGACGTGGCATTTCTGATCGCCAAGAAGATGCGCTCCAACGTGCGCGACCTGGAAGGCGCGCTCAACACGCTGGTGGCG
CGCGCCAACTTCACCGGGCGCTCGATCACGGTGGAATTCGCCCAGGAGACGCTGCGCGACCTGTTGCGCGCGCAGCAACA
GGCCATCGGCATCCCCAACATCCAGAAAACAGTAGCCGACTACTACGGCCTGCAGATGAAGGATTTGCTCTCCAAGCGCC
GCACGCGTTCGCTGGCACGTCCGCGCCAGGTGGCGATGGCGCTGGCCAAGGAGCTCACCGAACACAGCCTGCCGGAAATC
GGCGATGCCTTCGCCGGCCGCGACCACACCACCGTGCTGCATGCCTGCCGGCAGATCCGCACGCTGATGGAGGCAGACGG
CAAGCTGCGCGAGGACTGGGAAAAGCTGATTCGCAAGCTCAGCGAGTAG

Upstream 100 bases:

>100_bases
GTGTCCCCGGTGCTAGTCTGGCCCATCCTCTTTTCACTACCGGGCTGCGTGCACGGCGCCTTTCTGCGCGCCGCAGCCAG
CAACAGATGATCATACTTTG

Downstream 100 bases:

>100_bases
GCCTCGGACCCCAATCGTGTCCGCGCTGGAGAAAAGCGTGGAAACGTTGGGGTCAAATGCGGGAGAATCTGTGGATAACG
TTGCGTGGCGGTTCGATGGA

Product: chromosomal replication initiation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MDAWPRCLERLEAEFPPEDVHTWLKPLQAEDRGDSIVLYAPNAFIVDQVRERYLPRIRELLAYFAGNGEVALAVGSRPRA
PEPAPAPVAATIAPQAAPIAPFAGNLDSHYTFANFVEGRSNQLGLAAAIQAAQKPGDRAHNPLLLYGSTGLGKTHLMFAA
GNALRQAKPAAKVMYLRSEQFFSAMIRALQDKAMDQFKRQFQQIDALLIDDIQFFAGKDRTQEEFFHTFNALFDGRQQII
LTCDRYPREVEGLEPRLKSRLAWGLSVAIDPPDFETRAAIVLAKARERGAEIPDDVAFLIAKKMRSNVRDLEGALNTLVA
RANFTGRSITVEFAQETLRDLLRAQQQAIGIPNIQKTVADYYGLQMKDLLSKRRTRSLARPRQVAMALAKELTEHSLPEI
GDAFAGRDHTTVLHACRQIRTLMEADGKLREDWEKLIRKLSE

Sequences:

>Translated_442_residues
MDAWPRCLERLEAEFPPEDVHTWLKPLQAEDRGDSIVLYAPNAFIVDQVRERYLPRIRELLAYFAGNGEVALAVGSRPRA
PEPAPAPVAATIAPQAAPIAPFAGNLDSHYTFANFVEGRSNQLGLAAAIQAAQKPGDRAHNPLLLYGSTGLGKTHLMFAA
GNALRQAKPAAKVMYLRSEQFFSAMIRALQDKAMDQFKRQFQQIDALLIDDIQFFAGKDRTQEEFFHTFNALFDGRQQII
LTCDRYPREVEGLEPRLKSRLAWGLSVAIDPPDFETRAAIVLAKARERGAEIPDDVAFLIAKKMRSNVRDLEGALNTLVA
RANFTGRSITVEFAQETLRDLLRAQQQAIGIPNIQKTVADYYGLQMKDLLSKRRTRSLARPRQVAMALAKELTEHSLPEI
GDAFAGRDHTTVLHACRQIRTLMEADGKLREDWEKLIRKLSE
>Mature_442_residues
MDAWPRCLERLEAEFPPEDVHTWLKPLQAEDRGDSIVLYAPNAFIVDQVRERYLPRIRELLAYFAGNGEVALAVGSRPRA
PEPAPAPVAATIAPQAAPIAPFAGNLDSHYTFANFVEGRSNQLGLAAAIQAAQKPGDRAHNPLLLYGSTGLGKTHLMFAA
GNALRQAKPAAKVMYLRSEQFFSAMIRALQDKAMDQFKRQFQQIDALLIDDIQFFAGKDRTQEEFFHTFNALFDGRQQII
LTCDRYPREVEGLEPRLKSRLAWGLSVAIDPPDFETRAAIVLAKARERGAEIPDDVAFLIAKKMRSNVRDLEGALNTLVA
RANFTGRSITVEFAQETLRDLLRAQQQAIGIPNIQKTVADYYGLQMKDLLSKRRTRSLARPRQVAMALAKELTEHSLPEI
GDAFAGRDHTTVLHACRQIRTLMEADGKLREDWEKLIRKLSE

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family

Homologues:

Organism=Escherichia coli, GI2367267, Length=465, Percent_Identity=55.4838709677419, Blast_Score=518, Evalue=1e-148,
Organism=Escherichia coli, GI226510964, Length=231, Percent_Identity=28.1385281385281, Blast_Score=83, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DNAA_XANOR (Q5H715)

Other databases:

- EMBL:   AE013598
- RefSeq:   YP_198640.1
- ProteinModelPortal:   Q5H715
- GeneID:   3264935
- GenomeReviews:   AE013598_GR
- KEGG:   xoo:XOO0001
- NMPDR:   fig|291331.3.peg.233
- HOGENOM:   HBG695666
- OMA:   CHTLNAL
- ProtClustDB:   PRK00149
- BioCyc:   XORY291331:XOO0001-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00377
- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921
- Gene3D:   G3DSA:1.10.1750.10
- PRINTS:   PR00051
- SMART:   SM00382
- SMART:   SM00760
- TIGRFAMs:   TIGR00362

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C; SSF48295 Trp_repress_rep

EC number: NA

Molecular weight: Translated: 49513; Mature: 49513

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: PS01008 DNAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAWPRCLERLEAEFPPEDVHTWLKPLQAEDRGDSIVLYAPNAFIVDQVRERYLPRIREL
CCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
LAYFAGNGEVALAVGSRPRAPEPAPAPVAATIAPQAAPIAPFAGNLDSHYTFANFVEGRS
HHHHCCCCCEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHCCCC
NQLGLAAAIQAAQKPGDRAHNPLLLYGSTGLGKTHLMFAAGNALRQAKPAAKVMYLRSEQ
CCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHEEEECCHHHHHCCCHHHHHHHHHHH
FFSAMIRALQDKAMDQFKRQFQQIDALLIDDIQFFAGKDRTQEEFFHTFNALFDGRQQII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEE
LTCDRYPREVEGLEPRLKSRLAWGLSVAIDPPDFETRAAIVLAKARERGAEIPDDVAFLI
EECCCCCCHHCCCCHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHH
AKKMRSNVRDLEGALNTLVARANFTGRSITVEFAQETLRDLLRAQQQAIGIPNIQKTVAD
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
YYGLQMKDLLSKRRTRSLARPRQVAMALAKELTEHSLPEIGDAFAGRDHTTVLHACRQIR
HHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHH
TLMEADGKLREDWEKLIRKLSE
HHHHCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MDAWPRCLERLEAEFPPEDVHTWLKPLQAEDRGDSIVLYAPNAFIVDQVRERYLPRIREL
CCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
LAYFAGNGEVALAVGSRPRAPEPAPAPVAATIAPQAAPIAPFAGNLDSHYTFANFVEGRS
HHHHCCCCCEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHCCCC
NQLGLAAAIQAAQKPGDRAHNPLLLYGSTGLGKTHLMFAAGNALRQAKPAAKVMYLRSEQ
CCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHEEEECCHHHHHCCCHHHHHHHHHHH
FFSAMIRALQDKAMDQFKRQFQQIDALLIDDIQFFAGKDRTQEEFFHTFNALFDGRQQII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEE
LTCDRYPREVEGLEPRLKSRLAWGLSVAIDPPDFETRAAIVLAKARERGAEIPDDVAFLI
EECCCCCCHHCCCCHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHH
AKKMRSNVRDLEGALNTLVARANFTGRSITVEFAQETLRDLLRAQQQAIGIPNIQKTVAD
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
YYGLQMKDLLSKRRTRSLARPRQVAMALAKELTEHSLPEIGDAFAGRDHTTVLHACRQIR
HHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHH
TLMEADGKLREDWEKLIRKLSE
HHHHCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA