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The map label for this gene is thiL

Identifier: 84490342

GI number: 84490342

Start: 1739326

End: 1740327

Strand: Direct

Name: thiL

Synonym: Msp_1564

Alternate gene names: 84490342

Gene position: 1739326-1740327 (Clockwise)

Preceding gene: 84490341

Following gene: 84490343

Centisome position: 98.41

GC content: 27.74

Gene sequence:

>1002_bases
ATGAAAATATCAAAGATAGGCGAAAGAAAACTAATACAAAGACTTCTTAAGAAAAGAGATGAAACTCTAGGAAATATTGA
TAATACAATTCTTAAAAGTTACCATGATGATGCTGCAATAGAAGAAAATACTTCAAAATATACTGTCTTATCAACAGATA
TGCTTATACAACATTCTCATTTTCCAAAACAAATGACCTATTTTCAGATGGGAGAAAAAATAGTAACAGTAAATGTTAGT
GACATTCTTGCAATGAATGCAACACCAGTATCTATTCTCATAGCAATGGCACTTCCTAGCACATTAACAATAGATGAATT
TGATGAAATAATTGATGGTATTTTATATAAATGTAAGGAATATGGTGTAACTCTTATTGGAGGAGATCTTAATCAGTCAG
ATGAAATTATTCTTAGTGCAACTACCACGGGAAAAATAAATAAAAATATTAAATTACAAAGTAATATTCAAGAAGATAAT
CTGGTGGCTATAACAGGACAACTTGGAATGCCTGCTGCAGCACTAGATTTACTTAGCAAATATGAAATTAAAGATTTATC
TAATGAATATGAAGAGATTATAAAGAGTATTCTTGAACCAAATCTACCAATAAAAACTGCTAAATTTCTTAGAGAACATC
CCACACTCATCACTAGTATGACAGACATAACTGACGGACTTGCTATTGAATTAGGACATTTACATGAAAAAAATACCAAC
ATTGGATTTGAAATATATGCAGATAAACTTCCATATAACAAGCACATTTCACAAATAGCTACTGAAAATAACAAATCATT
AAATGAATACCTTCTCCATTTTGGAGAGGAATTTGAACTATTATTAACATTAGATAAAAAAGAATACTTGAAATATAAAG
ATAAATTAAATAATATACATATTATTGGTAAAGTAAATAACTCTGATAAAATTACATTAATAAGTCAAAAATCTGTTAAA
ACTATGAAAATAACAGGTTATGAACATTTAAAGGAGAATTAG

Upstream 100 bases:

>100_bases
TGATATTGTATCTGAAAAAGTAAATAAATACTTATAAACAATACAACAAAATAACCTCCCTTTTTTTAATACTAATTTTA
AAAATTTAATTATGATTAAT

Downstream 100 bases:

>100_bases
ATGACCTGCAATATCTGTCCAAATTATTGTAAATCTGATATAGATACAATTTGTAAACAAAACCCCCAATATGATGATGA
AAATGTAATTGATGCAGCCT

Product: hypothetical protein

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MKISKIGERKLIQRLLKKRDETLGNIDNTILKSYHDDAAIEENTSKYTVLSTDMLIQHSHFPKQMTYFQMGEKIVTVNVS
DILAMNATPVSILIAMALPSTLTIDEFDEIIDGILYKCKEYGVTLIGGDLNQSDEIILSATTTGKINKNIKLQSNIQEDN
LVAITGQLGMPAAALDLLSKYEIKDLSNEYEEIIKSILEPNLPIKTAKFLREHPTLITSMTDITDGLAIELGHLHEKNTN
IGFEIYADKLPYNKHISQIATENNKSLNEYLLHFGEEFELLLTLDKKEYLKYKDKLNNIHIIGKVNNSDKITLISQKSVK
TMKITGYEHLKEN

Sequences:

>Translated_333_residues
MKISKIGERKLIQRLLKKRDETLGNIDNTILKSYHDDAAIEENTSKYTVLSTDMLIQHSHFPKQMTYFQMGEKIVTVNVS
DILAMNATPVSILIAMALPSTLTIDEFDEIIDGILYKCKEYGVTLIGGDLNQSDEIILSATTTGKINKNIKLQSNIQEDN
LVAITGQLGMPAAALDLLSKYEIKDLSNEYEEIIKSILEPNLPIKTAKFLREHPTLITSMTDITDGLAIELGHLHEKNTN
IGFEIYADKLPYNKHISQIATENNKSLNEYLLHFGEEFELLLTLDKKEYLKYKDKLNNIHIIGKVNNSDKITLISQKSVK
TMKITGYEHLKEN
>Mature_333_residues
MKISKIGERKLIQRLLKKRDETLGNIDNTILKSYHDDAAIEENTSKYTVLSTDMLIQHSHFPKQMTYFQMGEKIVTVNVS
DILAMNATPVSILIAMALPSTLTIDEFDEIIDGILYKCKEYGVTLIGGDLNQSDEIILSATTTGKINKNIKLQSNIQEDN
LVAITGQLGMPAAALDLLSKYEIKDLSNEYEEIIKSILEPNLPIKTAKFLREHPTLITSMTDITDGLAIELGHLHEKNTN
IGFEIYADKLPYNKHISQIATENNKSLNEYLLHFGEEFELLLTLDKKEYLKYKDKLNNIHIIGKVNNSDKITLISQKSVK
TMKITGYEHLKEN

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=337, Percent_Identity=25.8160237388724, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 37686; Mature: 37686

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISKIGERKLIQRLLKKRDETLGNIDNTILKSYHDDAAIEENTSKYTVLSTDMLIQHSH
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHCCC
FPKQMTYFQMGEKIVTVNVSDILAMNATPVSILIAMALPSTLTIDEFDEIIDGILYKCKE
CCHHHHHHHCCCEEEEEEHHHHEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
YGVTLIGGDLNQSDEIILSATTTGKINKNIKLQSNIQEDNLVAITGQLGMPAAALDLLSK
CCEEEEECCCCCCCCEEEEEECCCCCCCCEEEECCCCCCCEEEEECCCCCCHHHHHHHHH
YEIKDLSNEYEEIIKSILEPNLPIKTAKFLREHPTLITSMTDITDGLAIELGHLHEKNTN
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHEEEHHHHCCCCEEEECCCCCCCCC
IGFEIYADKLPYNKHISQIATENNKSLNEYLLHFGEEFELLLTLDKKEYLKYKDKLNNIH
CCEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEEECHHHHHHHHHCCCCEE
IIGKVNNSDKITLISQKSVKTMKITGYEHLKEN
EEEEECCCCEEEEEECCCCEEEEEECHHHHCCC
>Mature Secondary Structure
MKISKIGERKLIQRLLKKRDETLGNIDNTILKSYHDDAAIEENTSKYTVLSTDMLIQHSH
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHCCC
FPKQMTYFQMGEKIVTVNVSDILAMNATPVSILIAMALPSTLTIDEFDEIIDGILYKCKE
CCHHHHHHHCCCEEEEEEHHHHEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
YGVTLIGGDLNQSDEIILSATTTGKINKNIKLQSNIQEDNLVAITGQLGMPAAALDLLSK
CCEEEEECCCCCCCCEEEEEECCCCCCCCEEEECCCCCCCEEEEECCCCCCHHHHHHHHH
YEIKDLSNEYEEIIKSILEPNLPIKTAKFLREHPTLITSMTDITDGLAIELGHLHEKNTN
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHEEEHHHHCCCCEEEECCCCCCCCC
IGFEIYADKLPYNKHISQIATENNKSLNEYLLHFGEEFELLLTLDKKEYLKYKDKLNNIH
CCEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEEECHHHHHHHHHCCCCEE
IIGKVNNSDKITLISQKSVKTMKITGYEHLKEN
EEEEECCCCEEEEEECCCCEEEEEECHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]