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The map label for this gene is purO

Identifier: 84490181

GI number: 84490181

Start: 1566164

End: 1566772

Strand: Direct

Name: purO

Synonym: Msp_1398

Alternate gene names: 84490181

Gene position: 1566164-1566772 (Clockwise)

Preceding gene: 84490180

Following gene: 84490182

Centisome position: 88.61

GC content: 31.86

Gene sequence:

>609_bases
ATGTATCTTGGAAGAATAATATCAATAGGAAGTAGTAAAGATGGTGTTTATGCATCATATAGAGTATCAAGCAGATCATT
TCCAAATCGTAAATCTGTAGTAAACAATCAAAAAGTAGCAATCATACCAACTCAAGGATCAGAAGATGATATCTATAAAA
ATCCATATATAAGCTACAACTGTATTGACATAATAGATGACATATGTGTTGTAACAAATGGATCACACACAGATATTATT
GCAGGTAAAATAAGAGAAGGTATGAATATGAAAGATGCTGTGGCTCTATCCCTTCTTACAATGGATTATGAAAAAGATGA
TTATAACACCCCCCGTATAGGTGGAGCAATAAATACTAAAGGTGAAGGTTACATAGGTATTGTAACACATGAAGGTATTG
AAGTTAAAAAAGTAAATCCTGGTGAATCCTTCTATGTATCAACATATGAACATAACACTCCCCGAGAAGTAGACTATACT
GCAACAAATGCAAAAGAAGCTACTGAATTCATATTTAATGGTGGAATATTTAGTGAATTTACACACCCTGTAACATCTTG
TGCAGCATTTAATAAAGATGAATGGGAAATAGATTTTAAAAATCCATAA

Upstream 100 bases:

>100_bases
TTAGCATCAATTGCTGTTAAAAGTCCAGCAAGTTCGTAAATAACTAAAAAAAAATACTCAGATAAATATTATTAGAAAAA
ATAGATAATGAGATGATAAA

Downstream 100 bases:

>100_bases
ATAAACTTAAACCCCAAATTCTTTTCTTTAATTTTTTAAGAACTTAACAGTATTGTTAGTGTTTTTTCAATAAAGATTTC
ATTGTTACTAAGTACTCTCC

Product: IMP cyclohydrolase

Products: NA

Alternate protein names: IMP synthase; Inosinicase

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MYLGRIISIGSSKDGVYASYRVSSRSFPNRKSVVNNQKVAIIPTQGSEDDIYKNPYISYNCIDIIDDICVVTNGSHTDII
AGKIREGMNMKDAVALSLLTMDYEKDDYNTPRIGGAINTKGEGYIGIVTHEGIEVKKVNPGESFYVSTYEHNTPREVDYT
ATNAKEATEFIFNGGIFSEFTHPVTSCAAFNKDEWEIDFKNP

Sequences:

>Translated_202_residues
MYLGRIISIGSSKDGVYASYRVSSRSFPNRKSVVNNQKVAIIPTQGSEDDIYKNPYISYNCIDIIDDICVVTNGSHTDII
AGKIREGMNMKDAVALSLLTMDYEKDDYNTPRIGGAINTKGEGYIGIVTHEGIEVKKVNPGESFYVSTYEHNTPREVDYT
ATNAKEATEFIFNGGIFSEFTHPVTSCAAFNKDEWEIDFKNP
>Mature_202_residues
MYLGRIISIGSSKDGVYASYRVSSRSFPNRKSVVNNQKVAIIPTQGSEDDIYKNPYISYNCIDIIDDICVVTNGSHTDII
AGKIREGMNMKDAVALSLLTMDYEKDDYNTPRIGGAINTKGEGYIGIVTHEGIEVKKVNPGESFYVSTYEHNTPREVDYT
ATNAKEATEFIFNGGIFSEFTHPVTSCAAFNKDEWEIDFKNP

Specific function: Catalyzes the cyclization of 5-formylamidoimidazole-4- carboxamide ribonucleotide to IMP

COG id: COG3363

COG function: function code F; Archaeal IMP cyclohydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal IMP cyclohydrolase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PURO_METST (Q2NEI3)

Other databases:

- EMBL:   CP000102
- RefSeq:   YP_448413.1
- ProteinModelPortal:   Q2NEI3
- SMR:   Q2NEI3
- STRING:   Q2NEI3
- GeneID:   3855304
- GenomeReviews:   CP000102_GR
- KEGG:   mst:Msp_1398
- NMPDR:   fig|339860.6.peg.1337
- eggNOG:   arNOG08037
- HOGENOM:   HBG539724
- OMA:   YIGRFLV
- ProtClustDB:   PRK04151
- BioCyc:   MSTA339860:MSP_1398-MONOMER
- HAMAP:   MF_00705
- InterPro:   IPR010191
- InterPro:   IPR020600
- Gene3D:   G3DSA:3.60.20.20
- PIRSF:   PIRSF004866
- TIGRFAMs:   TIGR01922

Pfam domain/function: PF07826 IMP_cyclohyd; SSF75569 PurO_cyclohydro

EC number: =3.5.4.10

Molecular weight: Translated: 22479; Mature: 22479

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLGRIISIGSSKDGVYASYRVSSRSFPNRKSVVNNQKVAIIPTQGSEDDIYKNPYISYN
CCCCEEEEECCCCCCEEEEEEECCCCCCCHHHHCCCCEEEEEECCCCCCCCCCCCCCEEE
CIDIIDDICVVTNGSHTDIIAGKIREGMNMKDAVALSLLTMDYEKDDYNTPRIGGAINTK
HHHHHCCEEEEECCCCCEEEEHHHHCCCCHHHHHEEEEEEEECCCCCCCCCCCCCEECCC
GEGYIGIVTHEGIEVKKVNPGESFYVSTYEHNTPREVDYTATNAKEATEFIFNGGIFSEF
CCCEEEEEEECCEEEEEECCCCCEEEEEECCCCCCEEEEEECCHHHHHHHEECCCCHHHH
THPVTSCAAFNKDEWEIDFKNP
HHHHHHHHHCCCCCEEEEECCC
>Mature Secondary Structure
MYLGRIISIGSSKDGVYASYRVSSRSFPNRKSVVNNQKVAIIPTQGSEDDIYKNPYISYN
CCCCEEEEECCCCCCEEEEEEECCCCCCCHHHHCCCCEEEEEECCCCCCCCCCCCCCEEE
CIDIIDDICVVTNGSHTDIIAGKIREGMNMKDAVALSLLTMDYEKDDYNTPRIGGAINTK
HHHHHCCEEEEECCCCCEEEEHHHHCCCCHHHHHEEEEEEEECCCCCCCCCCCCCEECCC
GEGYIGIVTHEGIEVKKVNPGESFYVSTYEHNTPREVDYTATNAKEATEFIFNGGIFSEF
CCCEEEEEEECCEEEEEECCCCCEEEEEECCCCCCEEEEEECCHHHHHHHEECCCCHHHH
THPVTSCAAFNKDEWEIDFKNP
HHHHHHHHHCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA