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The map label for this gene is frhG

Identifier: 84490092

GI number: 84490092

Start: 1468966

End: 1469736

Strand: Direct

Name: frhG

Synonym: Msp_1304

Alternate gene names: 84490092

Gene position: 1468966-1469736 (Clockwise)

Preceding gene: 84490091

Following gene: 84490093

Centisome position: 83.11

GC content: 31.65

Gene sequence:

>771_bases
TTGTTTGAAAAACTTAAGAATTTATTAAAAAGTGAAAATGAAAAAAAGATTGAAGCTCCACAAACTAAAAAATCAGGTGA
TAAATTAAAAATAGGTTATATTCATTTATCTGGATGTACTGGAGATTTAATGTCTTTTACTGAAAATTATGATGATTTTG
CAGATTTACTTGAAGCAGTAGATATTGTTTATGGACAAACATTAGTAGATGTTTGGGAAATGCCTGAGATGGATCTTGTT
CTCATTGAAGGATCTGTGTGTTTAGAAGATAAACATTCACTAAAAGAATTAAAAGAAGCAAGAAGTAAATCTAAATTATT
AGTTGCACTTGGATCTTGTGCTGCAACTGGTGGTTTTACAGTATATGCTAAAGGTGGACAACAAGCACAACCACAACATT
CATCATTTTTAGCTCTACAAAACATTGTGAAAGTAGATCTTGCAGTGCCTGGATGTCCTCCATCACCCGATATAATAAAG
AAAATTTTACTTGCTGCAATAAACAATGATATGGATTATCTTAAACCATTTATGGATTTTGCATCCAATAAGGAAGTATG
TGGCTGTGATTTACAGAAAAAAGTTTTAAATCACTCATTATGTATAGGTTGTGGAGCTTGTGCTGCAACATGCCCTACTC
GTGCCATGAGTATGAAAGATGGAAGACCATTATTTAATTGTGATAGATGTGTAAAATGTGGTTTATGTTACTATCAATGT
ACACGTAGTTGGTTACCAATAGACCAAATGAAAAAAGAAATAGGATATTAA

Upstream 100 bases:

>100_bases
ATCCCTGAAGCTGTTGAAATTACTATTAAATTACTTAATAAAATGTTAAAATGATTATATACTACAAAGGGAGATAAAAC
AATAAAAAAAGGTGAGTATC

Downstream 100 bases:

>100_bases
GGAGGAAATAAATTATGATACAAGATTCAGTTCTTGGACCACATCAAGAAATTATAACAGCAAAAGCTGCAGACAACAAA
GTTTTAAGTAAAGCTCAAGA

Product: FrhG

Products: NA

Alternate protein names: 8-hydroxy-5-deazaflavin-reducing hydrogenase subunit gamma; FRH [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MFEKLKNLLKSENEKKIEAPQTKKSGDKLKIGYIHLSGCTGDLMSFTENYDDFADLLEAVDIVYGQTLVDVWEMPEMDLV
LIEGSVCLEDKHSLKELKEARSKSKLLVALGSCAATGGFTVYAKGGQQAQPQHSSFLALQNIVKVDLAVPGCPPSPDIIK
KILLAAINNDMDYLKPFMDFASNKEVCGCDLQKKVLNHSLCIGCGACAATCPTRAMSMKDGRPLFNCDRCVKCGLCYYQC
TRSWLPIDQMKKEIGY

Sequences:

>Translated_256_residues
MFEKLKNLLKSENEKKIEAPQTKKSGDKLKIGYIHLSGCTGDLMSFTENYDDFADLLEAVDIVYGQTLVDVWEMPEMDLV
LIEGSVCLEDKHSLKELKEARSKSKLLVALGSCAATGGFTVYAKGGQQAQPQHSSFLALQNIVKVDLAVPGCPPSPDIIK
KILLAAINNDMDYLKPFMDFASNKEVCGCDLQKKVLNHSLCIGCGACAATCPTRAMSMKDGRPLFNCDRCVKCGLCYYQC
TRSWLPIDQMKKEIGY
>Mature_256_residues
MFEKLKNLLKSENEKKIEAPQTKKSGDKLKIGYIHLSGCTGDLMSFTENYDDFADLLEAVDIVYGQTLVDVWEMPEMDLV
LIEGSVCLEDKHSLKELKEARSKSKLLVALGSCAATGGFTVYAKGGQQAQPQHSSFLALQNIVKVDLAVPGCPPSPDIIK
KILLAAINNDMDYLKPFMDFASNKEVCGCDLQKKVLNHSLCIGCGACAATCPTRAMSMKDGRPLFNCDRCVKCGLCYYQC
TRSWLPIDQMKKEIGY

Specific function: Reduces the physiological low-potential two-electron acceptor coenzyme F420, and the artificial one-electron acceptor methylviologen [H]

COG id: COG1941

COG function: function code C; Coenzyme F420-reducing hydrogenase, gamma subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR017681
- InterPro:   IPR006137 [H]

Pfam domain/function: PF00037 Fer4; PF01058 Oxidored_q6 [H]

EC number: =1.12.98.1 [H]

Molecular weight: Translated: 28269; Mature: 28269

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
9.4 %Cys+Met (Translated Protein)
5.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
9.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEKLKNLLKSENEKKIEAPQTKKSGDKLKIGYIHLSGCTGDLMSFTENYDDFADLLEAV
CHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHCCHHHHHHHHHHH
DIVYGQTLVDVWEMPEMDLVLIEGSVCLEDKHSLKELKEARSKSKLLVALGSCAATGGFT
HHHHHHHHHHHHCCCCCCEEEEECCEEECCHHHHHHHHHHHHHHHEEEEECCCCCCCCEE
VYAKGGQQAQPQHSSFLALQNIVKVDLAVPGCPPSPDIIKKILLAAINNDMDYLKPFMDF
EEECCCCCCCCCHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
ASNKEVCGCDLQKKVLNHSLCIGCGACAATCPTRAMSMKDGRPLFNCDRCVKCGLCYYQC
CCCCCCCCCCHHHHHHCCHHHHCCCHHHHHCCHHHHCCCCCCCCCCHHHHHHHHHHHHHH
TRSWLPIDQMKKEIGY
HCCCCCHHHHHHHHCC
>Mature Secondary Structure
MFEKLKNLLKSENEKKIEAPQTKKSGDKLKIGYIHLSGCTGDLMSFTENYDDFADLLEAV
CHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHCCHHHHHHHHHHH
DIVYGQTLVDVWEMPEMDLVLIEGSVCLEDKHSLKELKEARSKSKLLVALGSCAATGGFT
HHHHHHHHHHHHCCCCCCEEEEECCEEECCHHHHHHHHHHHHHHHEEEEECCCCCCCCEE
VYAKGGQQAQPQHSSFLALQNIVKVDLAVPGCPPSPDIIKKILLAAINNDMDYLKPFMDF
EEECCCCCCCCCHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
ASNKEVCGCDLQKKVLNHSLCIGCGACAATCPTRAMSMKDGRPLFNCDRCVKCGLCYYQC
CCCCCCCCCCHHHHHHCCHHHHCCCHHHHHCCHHHHCCCCCCCCCCHHHHHHHHHHHHHH
TRSWLPIDQMKKEIGY
HCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2207102; 9371463; 3663585 [H]