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The map label for this gene is mch

Identifier: 84490026

GI number: 84490026

Start: 1408083

End: 1409069

Strand: Direct

Name: mch

Synonym: Msp_1238

Alternate gene names: 84490026

Gene position: 1408083-1409069 (Clockwise)

Preceding gene: 84490025

Following gene: 84490027

Centisome position: 79.67

GC content: 31.1

Gene sequence:

>987_bases
ATGAGTGAAAGTATGAACATAGCAGCAAAGAAAATTGCTGATAAAATGGTTCAAGATGCAGAAAAATTAAAAGTAATTCC
ATCAACATTATCCAATGGAACATCTATTATAGATTGTGGTGTTAATGCTAAGGGAAGTATTAAAGGTGGGGAATTATTTA
CAAAAGTATGTCTTGGTGGAATTTGTGATGTTGGAATTTCAATACCTGGTGACTTAAGTGATATAATGGCTATGCCTGCT
GTTAAGGTTAAAACTGATTTTCCAGCATTAACCACTCTTGGTTCTCAGAAAGCAGGATGGAAAATAGATGTTAATGGATA
TTATGCTATAGGTTCTGGACCTGCTCAGACACATAAATTTAAAGATAATAACATTTATAAAATAACTAACTATATTGAAG
ATTCAGATATTGCAGTTATTACTCTTGAAGCAGATAAATTACCTGATGAAGATATTGCTAATTATATTGCAGATGAGTGT
GGTGTAAAACCAGAAAATTTAACCATACTTGTTGCACCTACATCTTCTCTTGTTGGATCTATTCAAATATCTGGTAGAGC
TCTTGAAACTGGAATATACAAAATGTATGAAATAATGAACTTCGATGTTACTAAAATTACATATGCTGCAGGTATTACCC
CTATTACACCAGTTGATCCTGATAGTCTTAAAGCTATGGGTAAAACTAATGATGCTATCATGTTTGGTGGAAGAGCATAT
TATTATATTGAACCTGATGAAGGTGAAGATTTAGAAGAATTAGCTGCTAATTTACCATCATCTGCTTCTGATAATTATGG
TCAAAGCTTTATTGAATTATTTAAAGAAGCAAATCAGGATTTCTATAAAATGCCTAAGGATATTTTTGCACCAGCACAAG
TTATTGTTAATGATATGATAACTGGTCAAATGTTCCACACAGGATTTATAGATCTTAAACGTCTAAAAAAATCTTTTGAA
GTTAAAGAAATAATTTATGAAAAATAA

Upstream 100 bases:

>100_bases
TTATTAGTTAAAAAAAGCTAGATATAATATTATATTACCTATAATGAGAAATAACTCATTATTGATATATTTTAAATTAT
TATTTAATGGAGATAAAAGC

Downstream 100 bases:

>100_bases
TTTTTCAATAGGAGTGTTGTTAAATAATGTCAAAAAGAATAGGAATTTGTAGTACTACCTTTGCACGATTTGATATGGCA
AGTGCAGCAATTAAACAAAT

Product: N(5),N(10)-methenyltetrahydromethanopterin cyclohydrolase

Products: NA

Alternate protein names: Methenyl-H4MPT cyclohydrolase [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MSESMNIAAKKIADKMVQDAEKLKVIPSTLSNGTSIIDCGVNAKGSIKGGELFTKVCLGGICDVGISIPGDLSDIMAMPA
VKVKTDFPALTTLGSQKAGWKIDVNGYYAIGSGPAQTHKFKDNNIYKITNYIEDSDIAVITLEADKLPDEDIANYIADEC
GVKPENLTILVAPTSSLVGSIQISGRALETGIYKMYEIMNFDVTKITYAAGITPITPVDPDSLKAMGKTNDAIMFGGRAY
YYIEPDEGEDLEELAANLPSSASDNYGQSFIELFKEANQDFYKMPKDIFAPAQVIVNDMITGQMFHTGFIDLKRLKKSFE
VKEIIYEK

Sequences:

>Translated_328_residues
MSESMNIAAKKIADKMVQDAEKLKVIPSTLSNGTSIIDCGVNAKGSIKGGELFTKVCLGGICDVGISIPGDLSDIMAMPA
VKVKTDFPALTTLGSQKAGWKIDVNGYYAIGSGPAQTHKFKDNNIYKITNYIEDSDIAVITLEADKLPDEDIANYIADEC
GVKPENLTILVAPTSSLVGSIQISGRALETGIYKMYEIMNFDVTKITYAAGITPITPVDPDSLKAMGKTNDAIMFGGRAY
YYIEPDEGEDLEELAANLPSSASDNYGQSFIELFKEANQDFYKMPKDIFAPAQVIVNDMITGQMFHTGFIDLKRLKKSFE
VKEIIYEK
>Mature_327_residues
SESMNIAAKKIADKMVQDAEKLKVIPSTLSNGTSIIDCGVNAKGSIKGGELFTKVCLGGICDVGISIPGDLSDIMAMPAV
KVKTDFPALTTLGSQKAGWKIDVNGYYAIGSGPAQTHKFKDNNIYKITNYIEDSDIAVITLEADKLPDEDIANYIADECG
VKPENLTILVAPTSSLVGSIQISGRALETGIYKMYEIMNFDVTKITYAAGITPITPVDPDSLKAMGKTNDAIMFGGRAYY
YIEPDEGEDLEELAANLPSSASDNYGQSFIELFKEANQDFYKMPKDIFAPAQVIVNDMITGQMFHTGFIDLKRLKKSFEV
KEIIYEK

Specific function: Catalyzes the reversible interconversion of 5-formyl- H(4)MPT to methenyl-H(4)MPT(+) [H]

COG id: COG3252

COG function: function code H; Methenyltetrahydromethanopterin cyclohydrolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MCH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003209 [H]

Pfam domain/function: PF02289 MCH [H]

EC number: =3.5.4.27 [H]

Molecular weight: Translated: 35715; Mature: 35584

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESMNIAAKKIADKMVQDAEKLKVIPSTLSNGTSIIDCGVNAKGSIKGGELFTKVCLGG
CCCCHHHHHHHHHHHHHHHHHHHEECHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
ICDVGISIPGDLSDIMAMPAVKVKTDFPALTTLGSQKAGWKIDVNGYYAIGSGPAQTHKF
HHHCCCCCCCCHHHHHHCCCEEEECCCCHHHHCCCCCCCEEEECCEEEEECCCCCCCCEE
KDNNIYKITNYIEDSDIAVITLEADKLPDEDIANYIADECGVKPENLTILVAPTSSLVGS
CCCCEEEEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHEEE
IQISGRALETGIYKMYEIMNFDVTKITYAAGITPITPVDPDSLKAMGKTNDAIMFGGRAY
EEECCCHHHHHHHHHHHHHCCCHHEEEEECCCCCCCCCCHHHHHHCCCCCCEEEECCEEE
YYIEPDEGEDLEELAANLPSSASDNYGQSFIELFKEANQDFYKMPKDIFAPAQVIVNDMI
EEEECCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHH
TGQMFHTGFIDLKRLKKSFEVKEIIYEK
HCHHHHCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SESMNIAAKKIADKMVQDAEKLKVIPSTLSNGTSIIDCGVNAKGSIKGGELFTKVCLGG
CCCHHHHHHHHHHHHHHHHHHHEECHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
ICDVGISIPGDLSDIMAMPAVKVKTDFPALTTLGSQKAGWKIDVNGYYAIGSGPAQTHKF
HHHCCCCCCCCHHHHHHCCCEEEECCCCHHHHCCCCCCCEEEECCEEEEECCCCCCCCEE
KDNNIYKITNYIEDSDIAVITLEADKLPDEDIANYIADECGVKPENLTILVAPTSSLVGS
CCCCEEEEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHEEE
IQISGRALETGIYKMYEIMNFDVTKITYAAGITPITPVDPDSLKAMGKTNDAIMFGGRAY
EEECCCHHHHHHHHHHHHHCCCHHEEEEECCCCCCCCCCHHHHHHCCCCCCEEEECCEEE
YYIEPDEGEDLEELAANLPSSASDNYGQSFIELFKEANQDFYKMPKDIFAPAQVIVNDMI
EEEECCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHH
TGQMFHTGFIDLKRLKKSFEVKEIIYEK
HCHHHHCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]