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The map label for this gene is cbiJ

Identifier: 84489997

GI number: 84489997

Start: 1375840

End: 1376613

Strand: Direct

Name: cbiJ

Synonym: Msp_1205

Alternate gene names: 84489997

Gene position: 1375840-1376613 (Clockwise)

Preceding gene: 84489996

Following gene: 84489999

Centisome position: 77.85

GC content: 28.68

Gene sequence:

>774_bases
ATGAGATATATGGTGATGTCTGGTACATCTGATTCAACAAAAGTTATTAAGTTTTTAAGGGAAGATAAAAATAATTATAT
TCTTGCTACAACTGTCACAGATTATGGTTCAGAAATAGCAAAATCTGCAGGGGCAGATGAAGTTATATCAAAAGCTTTGA
AAGAAGAAGATTTTATAAATGTAATTAAAGAAAAAAATATAGACACCTTAATTGATGCTACCCATCCTTTTGCAGCAGTA
GCAACAGAAACTGCAATTGAAAGTTGTGAAAAAGCTAGAATAAATTATATTAGATATGAACGAGCTTCAACAATCTTACC
TGACTCAGATTTAATATACAAAGTACCTTCATTTTCCAAAGGTGCTCTAAAAGCTAAAGAATTATTAAAAGAAAAAAATG
ATAAGTTAATGCATTTAGCTGGAGTTATGACACTTCATGAAATAGTAAAAGAAGTTAATCCACAACAAGTTATTGCAAGA
GTTCTTCCAAATACATTTAGTATTACAAAAACCCAAAAAAATGGTATTCCTGCAGAAAATATCATTGCAATGCAGGGCAC
ATTCTCTAAAGAATTTAATATTAGTCTTATGAAAGAATATTCAGTTAGTGCAATAATAACCAAAGAAAGTGGTGAAAGTG
GTGGTGCTGAAGAAAAAATCAATGCTGCTCTTGAATTAAATATACCTGTAATATTAGTTACAAGACCAATTGTTAAAAAA
TTAGAAAACCATACTATAGTTAGATCTATATATGAATTGAAAAAAAATATTTAA

Upstream 100 bases:

>100_bases
TAATAAAAAAAGAATATAATAACAAAATAAGTATATAAATATGATTTTTTGAAAAAAAAGTATAGTATAATTCATTAGAT
TATAATATTGGAGGGAAAAT

Downstream 100 bases:

>100_bases
AAACTTTTTTTCTTAATTAAATTTTTTTTAAAATAAAAAAATAAGCATTTTATTTTGGTGGTTAAAGTAAAAATAGCCTC
AGATCGCCCATCATTCATCA

Product: CbiJ

Products: Precorrin 6A; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MRYMVMSGTSDSTKVIKFLREDKNNYILATTVTDYGSEIAKSAGADEVISKALKEEDFINVIKEKNIDTLIDATHPFAAV
ATETAIESCEKARINYIRYERASTILPDSDLIYKVPSFSKGALKAKELLKEKNDKLMHLAGVMTLHEIVKEVNPQQVIAR
VLPNTFSITKTQKNGIPAENIIAMQGTFSKEFNISLMKEYSVSAIITKESGESGGAEEKINAALELNIPVILVTRPIVKK
LENHTIVRSIYELKKNI

Sequences:

>Translated_257_residues
MRYMVMSGTSDSTKVIKFLREDKNNYILATTVTDYGSEIAKSAGADEVISKALKEEDFINVIKEKNIDTLIDATHPFAAV
ATETAIESCEKARINYIRYERASTILPDSDLIYKVPSFSKGALKAKELLKEKNDKLMHLAGVMTLHEIVKEVNPQQVIAR
VLPNTFSITKTQKNGIPAENIIAMQGTFSKEFNISLMKEYSVSAIITKESGESGGAEEKINAALELNIPVILVTRPIVKK
LENHTIVRSIYELKKNI
>Mature_257_residues
MRYMVMSGTSDSTKVIKFLREDKNNYILATTVTDYGSEIAKSAGADEVISKALKEEDFINVIKEKNIDTLIDATHPFAAV
ATETAIESCEKARINYIRYERASTILPDSDLIYKVPSFSKGALKAKELLKEKNDKLMHLAGVMTLHEIVKEVNPQQVIAR
VLPNTFSITKTQKNGIPAENIIAMQGTFSKEFNISLMKEYSVSAIITKESGESGGAEEKINAALELNIPVILVTRPIVKK
LENHTIVRSIYELKKNI

Specific function: Catalyzes the reduction of the macrocycle of cobalt- precorrin-6X into cobalt-precorrin-6Y [H]

COG id: COG2099

COG function: function code H; Precorrin-6x reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin-6x reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003723 [H]

Pfam domain/function: PF02571 CbiJ [H]

EC number: 1.3.1.54

Molecular weight: Translated: 28610; Mature: 28610

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: PS51014 COBK_CBIJ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYMVMSGTSDSTKVIKFLREDKNNYILATTVTDYGSEIAKSAGADEVISKALKEEDFIN
CEEEEECCCCCHHHHHHHHHHCCCCEEEEEEECHHHHHHHHCCCHHHHHHHHHHHHHHHH
VIKEKNIDTLIDATHPFAAVATETAIESCEKARINYIRYERASTILPDSDLIYKVPSFSK
HHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEHHHCCCCCCCCCEEECCCCCC
GALKAKELLKEKNDKLMHLAGVMTLHEIVKEVNPQQVIARVLPNTFSITKTQKNGIPAEN
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEECCCCCCCHHH
IIAMQGTFSKEFNISLMKEYSVSAIITKESGESGGAEEKINAALELNIPVILVTRPIVKK
EEEECCCCCCCCCCEEEECCCEEEEEEECCCCCCCCHHHCCEEEEECCCEEEECCHHHHH
LENHTIVRSIYELKKNI
HHCHHHHHHHHHHHHCC
>Mature Secondary Structure
MRYMVMSGTSDSTKVIKFLREDKNNYILATTVTDYGSEIAKSAGADEVISKALKEEDFIN
CEEEEECCCCCHHHHHHHHHHCCCCEEEEEEECHHHHHHHHCCCHHHHHHHHHHHHHHHH
VIKEKNIDTLIDATHPFAAVATETAIESCEKARINYIRYERASTILPDSDLIYKVPSFSK
HHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEHHHCCCCCCCCCEEECCCCCC
GALKAKELLKEKNDKLMHLAGVMTLHEIVKEVNPQQVIARVLPNTFSITKTQKNGIPAEN
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEECCCCCCCHHH
IIAMQGTFSKEFNISLMKEYSVSAIITKESGESGGAEEKINAALELNIPVILVTRPIVKK
EEEECCCCCCCCCCEEEECCCEEEEEEECCCCCCCCHHHCCEEEEECCCEEEECCHHHHH
LENHTIVRSIYELKKNI
HHCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 6B; NADP+

Specific reaction: precorrin-6B + NADP+ = precorrin-6A + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]