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The map label for this gene is queC

Identifier: 84489963

GI number: 84489963

Start: 1341289

End: 1341969

Strand: Direct

Name: queC

Synonym: Msp_1171

Alternate gene names: 84489963

Gene position: 1341289-1341969 (Clockwise)

Preceding gene: 84489962

Following gene: 84489964

Centisome position: 75.89

GC content: 28.78

Gene sequence:

>681_bases
ATGAAACCTAAAGCAATAACTGTACTCTCTGGAGGATTAGATTCAACAGTTGCCACATCAATTTATGCAAATGATTATGA
TATAACTGCAATCACATTTAATTATGGTCAACAAAGTATAAAACAAGAATTAAAACATGCAAAAATGATATGTGAAAAAT
TAGATATGAAACATATTGTAATAGATCTTCCATGGCTTAAAGAAATTAGTAATTCAAGTTTAACAACAGATAAAAGCATA
CCTCAACCAAGTGATAATGACTTAGATGATTATGATAAATCTATTGAAACAGCAAAATCTGTATGGGTTCCTGCAAGAAA
TACTGTTTTTTGTAGTATTGCCTTATCATATGCTGAAAGTATTCAAGCCAAAATAATTATTGTAGGATGGGATTATGAAG
AAGCTGTTACATTTCCTGATAATTCAAAAGAATACCTGAAATCTTTTAATGAAACTATAAAATATGGTTCTTTTGATGAT
ATTGAAATTAAAGCTCCCTTAATTGACATGACAAAAGAAGATATTGTTAAAAAAGGTCATGAAGTAAATGCTCCTATGAA
TATAAGTTATTCATGTTATGTTGGATGTGACACACACTGTGGAGTATGTGAATCTTGTAAAAGAAGAAAAAGAGCATTCA
CAAGAGCAAATGTAACTGATTATACAGAATATGAAAAATAG

Upstream 100 bases:

>100_bases
TGATGATATTAAAAAAATAGCCAATAAAACATCCATTCCTATTAAAGATTTAATAAAATATGTAGAAATGGAATATAGAA
TAAATAATAGAGGAGATTAA

Downstream 100 bases:

>100_bases
GTGATTAAAATGAGTAACATTGAATATGAAGTTAAAAGACAACGTAAAACTCTTACTACCAAGGAATTTTATGATAGATT
TTCAAACTTTGAAGTAGTTC

Product: ATPase

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; Archaeosine biosynthesis protein queC; PreQ(0) synthase

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MKPKAITVLSGGLDSTVATSIYANDYDITAITFNYGQQSIKQELKHAKMICEKLDMKHIVIDLPWLKEISNSSLTTDKSI
PQPSDNDLDDYDKSIETAKSVWVPARNTVFCSIALSYAESIQAKIIIVGWDYEEAVTFPDNSKEYLKSFNETIKYGSFDD
IEIKAPLIDMTKEDIVKKGHEVNAPMNISYSCYVGCDTHCGVCESCKRRKRAFTRANVTDYTEYEK

Sequences:

>Translated_226_residues
MKPKAITVLSGGLDSTVATSIYANDYDITAITFNYGQQSIKQELKHAKMICEKLDMKHIVIDLPWLKEISNSSLTTDKSI
PQPSDNDLDDYDKSIETAKSVWVPARNTVFCSIALSYAESIQAKIIIVGWDYEEAVTFPDNSKEYLKSFNETIKYGSFDD
IEIKAPLIDMTKEDIVKKGHEVNAPMNISYSCYVGCDTHCGVCESCKRRKRAFTRANVTDYTEYEK
>Mature_226_residues
MKPKAITVLSGGLDSTVATSIYANDYDITAITFNYGQQSIKQELKHAKMICEKLDMKHIVIDLPWLKEISNSSLTTDKSI
PQPSDNDLDDYDKSIETAKSVWVPARNTVFCSIALSYAESIQAKIIIVGWDYEEAVTFPDNSKEYLKSFNETIKYGSFDD
IEIKAPLIDMTKEDIVKKGHEVNAPMNISYSCYVGCDTHCGVCESCKRRKRAFTRANVTDYTEYEK

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=216, Percent_Identity=30.5555555555556, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_METST (Q2NF51)

Other databases:

- EMBL:   CP000102
- RefSeq:   YP_448195.1
- ProteinModelPortal:   Q2NF51
- SMR:   Q2NF51
- STRING:   Q2NF51
- GeneID:   3856067
- GenomeReviews:   CP000102_GR
- KEGG:   mst:Msp_1171
- NMPDR:   fig|339860.6.peg.1123
- eggNOG:   arNOG08306
- HOGENOM:   HBG553284
- OMA:   GWAEVLG
- PhylomeDB:   Q2NF51
- ProtClustDB:   CLSK798079
- BioCyc:   MSTA339860:MSP_1171-MONOMER
- HAMAP:   MF_01633_A
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 25532; Mature: 25532

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPKAITVLSGGLDSTVATSIYANDYDITAITFNYGQQSIKQELKHAKMICEKLDMKHIV
CCCCEEEEEECCCCCHHHHEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEE
IDLPWLKEISNSSLTTDKSIPQPSDNDLDDYDKSIETAKSVWVPARNTVFCSIALSYAES
EECHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEECCCCCCEEEEEHHHHHHC
IQAKIIIVGWDYEEAVTFPDNSKEYLKSFNETIKYGSFDDIEIKAPLIDMTKEDIVKKGH
CEEEEEEEECCHHHEEECCCCCHHHHHHHHHHHCCCCCCCEEEECCHHHCCHHHHHHCCC
EVNAPMNISYSCYVGCDTHCGVCESCKRRKRAFTRANVTDYTEYEK
CCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKPKAITVLSGGLDSTVATSIYANDYDITAITFNYGQQSIKQELKHAKMICEKLDMKHIV
CCCCEEEEEECCCCCHHHHEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEE
IDLPWLKEISNSSLTTDKSIPQPSDNDLDDYDKSIETAKSVWVPARNTVFCSIALSYAES
EECHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEECCCCCCEEEEEHHHHHHC
IQAKIIIVGWDYEEAVTFPDNSKEYLKSFNETIKYGSFDDIEIKAPLIDMTKEDIVKKGH
CEEEEEEEECCHHHEEECCCCCHHHHHHHHHHHCCCCCCCEEEECCHHHCCHHHHHHCCC
EVNAPMNISYSCYVGCDTHCGVCESCKRRKRAFTRANVTDYTEYEK
CCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA