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The map label for this gene is cofC

Identifier: 84489805

GI number: 84489805

Start: 1154157

End: 1154843

Strand: Direct

Name: cofC

Synonym: Msp_1006

Alternate gene names: 84489805

Gene position: 1154157-1154843 (Clockwise)

Preceding gene: 84489804

Following gene: 84489806

Centisome position: 65.3

GC content: 24.02

Gene sequence:

>687_bases
ATGAATAAAATAATTACTATAATACCTATATCTAGTTTTAATAATTCTAAAACACGTCTTTCTCCATTTTTATCTGAAAG
TGAGAGAACTAATCTACTAAAAGTCATGTTGAAAGATATTGTTAGTAATATTCAAGATCATGTATCTGATATTATAGTTA
CTAGTAAGGATGAATATGTTCTAAATTATGCAAAATATCTTAATTTAAATGTTTTTAAGGAAAAAGAACATGAACATGAT
TTTTTAAATAATGCTATTAGTGATGCTATTAGTTATATTAGTAAAAATTATGATAATTACAGTGTTATGATATTACCAGC
TGATATTCCACTTTTTAACTCTAGAAATATGAAGTATATTCTCAAAAATAGGGATGATTTTATTATTTCACCATCAAAGG
GTGGTGGTACTAATTTATTATACATAAATAGAGAATATAATTATAAGCCATTATTTGGTGCATTTAGTTTCTTTAAACAT
GTTCAAGAGGCTAAAAATAATAATTTAGATGTTAATATTTATGATTCCTTTTATTTATCATTGGATGTTAATACTCCTGA
GGATTTAGGTGAGATTTTATTACATGGAAGAAATACCCATACATATAATTATCTTAGTAATTTAAATATTGGTGTTGAAA
GTAATCATGGAAAGGAGCGACTTTATGTCTATAGAAAAAATGAATAA

Upstream 100 bases:

>100_bases
GGAACTGCTGTTAAATTTACAGATTGAAATTAATCTTTTTTTATTAAAAATTCTATTTTTTTTAGAATAATATATTTATT
TTTTTAGACAATAATTAATT

Downstream 100 bases:

>100_bases
AAAATGTAGTATGACTATTGCAGGACTTGATCCTTCTGGTGGAGCTGGTATTATTGCTGACTGTAAAACATTTCATGCTC
ATGGTATTTATGCAACATGT

Product: hypothetical protein

Products: NA

Alternate protein names: LP guanylyltransferase

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MNKIITIIPISSFNNSKTRLSPFLSESERTNLLKVMLKDIVSNIQDHVSDIIVTSKDEYVLNYAKYLNLNVFKEKEHEHD
FLNNAISDAISYISKNYDNYSVMILPADIPLFNSRNMKYILKNRDDFIISPSKGGGTNLLYINREYNYKPLFGAFSFFKH
VQEAKNNNLDVNIYDSFYLSLDVNTPEDLGEILLHGRNTHTYNYLSNLNIGVESNHGKERLYVYRKNE

Sequences:

>Translated_228_residues
MNKIITIIPISSFNNSKTRLSPFLSESERTNLLKVMLKDIVSNIQDHVSDIIVTSKDEYVLNYAKYLNLNVFKEKEHEHD
FLNNAISDAISYISKNYDNYSVMILPADIPLFNSRNMKYILKNRDDFIISPSKGGGTNLLYINREYNYKPLFGAFSFFKH
VQEAKNNNLDVNIYDSFYLSLDVNTPEDLGEILLHGRNTHTYNYLSNLNIGVESNHGKERLYVYRKNE
>Mature_228_residues
MNKIITIIPISSFNNSKTRLSPFLSESERTNLLKVMLKDIVSNIQDHVSDIIVTSKDEYVLNYAKYLNLNVFKEKEHEHD
FLNNAISDAISYISKNYDNYSVMILPADIPLFNSRNMKYILKNRDDFIISPSKGGGTNLLYINREYNYKPLFGAFSFFKH
VQEAKNNNLDVNIYDSFYLSLDVNTPEDLGEILLHGRNTHTYNYLSNLNIGVESNHGKERLYVYRKNE

Specific function: Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor

COG id: COG1920

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CofC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COFC_METST (Q2NFK9)

Other databases:

- EMBL:   CP000102
- RefSeq:   YP_448037.1
- ProteinModelPortal:   Q2NFK9
- SMR:   Q2NFK9
- STRING:   Q2NFK9
- GeneID:   3855252
- GenomeReviews:   CP000102_GR
- KEGG:   mst:Msp_1006
- NMPDR:   fig|339860.6.peg.965
- eggNOG:   arNOG08928
- HOGENOM:   HBG699055
- OMA:   SSAGRFN
- ProtClustDB:   CLSK876373
- BioCyc:   MSTA339860:MSP_1006-MONOMER
- HAMAP:   MF_02114
- InterPro:   IPR002835
- TIGRFAMs:   TIGR03552

Pfam domain/function: PF01983 DUF121

EC number: =2.7.7.68

Molecular weight: Translated: 26498; Mature: 26498

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKIITIIPISSFNNSKTRLSPFLSESERTNLLKVMLKDIVSNIQDHVSDIIVTSKDEYV
CCCEEEEEEECCCCCCCHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHH
LNYAKYLNLNVFKEKEHEHDFLNNAISDAISYISKNYDNYSVMILPADIPLFNSRNMKYI
HHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEECCCCCEEE
LKNRDDFIISPSKGGGTNLLYINREYNYKPLFGAFSFFKHVQEAKNNNLDVNIYDSFYLS
EECCCCEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEEE
LDVNTPEDLGEILLHGRNTHTYNYLSNLNIGVESNHGKERLYVYRKNE
EECCCHHHHHHHHCCCCCCCEEEEHCCCEEEEECCCCCEEEEEEECCC
>Mature Secondary Structure
MNKIITIIPISSFNNSKTRLSPFLSESERTNLLKVMLKDIVSNIQDHVSDIIVTSKDEYV
CCCEEEEEEECCCCCCCHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHH
LNYAKYLNLNVFKEKEHEHDFLNNAISDAISYISKNYDNYSVMILPADIPLFNSRNMKYI
HHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEECCCCCEEE
LKNRDDFIISPSKGGGTNLLYINREYNYKPLFGAFSFFKHVQEAKNNNLDVNIYDSFYLS
EECCCCEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEEE
LDVNTPEDLGEILLHGRNTHTYNYLSNLNIGVESNHGKERLYVYRKNE
EECCCHHHHHHHHCCCCCCCEEEEHCCCEEEEECCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA