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The map label for this gene is ctpC [H]

Identifier: 84489626

GI number: 84489626

Start: 957685

End: 959802

Strand: Direct

Name: ctpC [H]

Synonym: Msp_0826

Alternate gene names: 84489626

Gene position: 957685-959802 (Clockwise)

Preceding gene: 84489625

Following gene: 84489627

Centisome position: 54.19

GC content: 30.26

Gene sequence:

>2118_bases
ATGAAATTTAAAATAGTTTATGATAACAACAAGGACATAATACGTGTTCGTGCAGGAAGAGCTGCATTCACAACCAGTGA
AGGATATGGATTATCCCAATTACTTTCCCAAAAAAAAGGTATCAAAACTGTTAAAGTTTCATCTACCAATGGTAGTATTC
ATATAAAATACTCTGGTAATAAAAACAGAGTATTTAAATATTTAGCAAACTTAAAAAAATCAGACTTATATGAAGCTGAA
CCAACAACTGAAGAACTATCAAGAGAAACTAATAATCATTACATTAATAAAATACTTAAAAAAATAGTTGGTAGATATGC
AGCACAACTCTTTTTACCAACACCACTTAATATTATTAAGATTGTTTATGAATCTATACCATACATAGTTAAAGGTATTG
ATAGTTTAATACATATGAGAATAGATGTAGATTTATTAGATGCAACATCCCTTGCTGTAACATTAAGTCAAGGAATGTTT
GGACCAGCAGGATCTATTGTATTTTTACTCGGATTATCAGAAATACTTGAAGAATACACAATAGAAAAAACAAAACACTC
ACTTGAAAACAGTTTAATGTTAAATATAAATAAAGTATGGATTGAAACTGAAACAAATGAAGAAGTACAAATACCATTTA
CACAACTTAAAGAAAAAGACAAAGTTATTGTAAGAACAGGTACAATCATACCTGCAGATGGTGTTATTATAAAAGGAAAT
GCTGAAATTAACGAAGCAACAATGACTGGTGAATCATTACCAGTATCTAAAAATGTTGGAAAAGCAGTATTTGCAGGAAC
AATTGTTGAAAATGGTTCAATAACTGTTGAAGTTGAAGCAATAAATGAATCAACTAGAATAAATCAAATCATTGATTTAA
TTGAAAGTTCTGATAAACTCAAGGCAGGAATCCAAAGTAAAGCTGAAAAATTAGCAGATTCAATAGTTCCATGGAATTTT
GCAATAACACTATTAACATATATTATAACTGGAAGTACAATAAAAGCTATTGCAGCACTAACTGTAGATTATTCATGTGC
AATTAAACTTGCAACACCAATATCTATCATATCAGCAATGAGAGAAGCTTCAGAAAGAGAAGTTGTTGTTAAAGGTGGAA
GATATCTTGAAGCTTATGCAACAGCAGATACAATAATATTTGATAAAACTGGAACATTAACTAAGTCATGCCCAGAAGTT
GCTAAAGTTGTATCTCTTGGTGCATTATCTGATGAAGAATTACTCAGACAAGCAGCATGTATTGAAGAACATTTCCCTCA
TAGTGTAGCTACTGCTATTGTAAATAAAGCTAAAGAACTTGGCCTAAATCATGGAGAAGAATTACACTCTGAAGTAGAAT
ATATTGTAGCTCATGGAATTGCAACCACATTAGATGGAAAACGTGCCGTATTAGGTAGTCAACACTTTGTACTTGAAGAT
GAAAATGTAAAAATTACAAAGGAAAAAGAAGATATTATATCTGAAAATGTTGATAAATATTCTGTAATATACTTTGCTAT
AGACAGAGTACTTGAAGGAATTATATGTATATATGATCCTCCACGTGATGAAGCAAAAGTAGTGCTTAATAAACTTAGAA
GTTTAGGAATTAAGGATATTGTAATGCTTACAGGAGATTCTGAAAATGCCGCAGCAACAACTGCTAAATTATTAGGAATA
AATCATTATAGATCTCAGGTACTACCTGAAGATAAAGCAAGTATTGTAGAAGAAATAAAAGAAAAAGGCAAGAAAGTAAT
AATGGTGGGAGATGGTATTAATGATTCACCAGCATTATCTGCAGCTGATGTATCTGTAGCAATGAAAGATTCATCTGATC
TTGCTAGAGAAGTAGCAGATATTACCTTACTTCGACCTTCATTAAATGATCTAATAACTATTAGATTATTAAGCCAACAA
ATGCTTGATTTAATACATAGAAATTATAAATTAATACTTCTATTGAATACAACATTCATGGCATTAGGTCTTAGTGGAGT
TATATCCCCATCTGCAACATCAGTATTACATAATGGTTCTACAATGCTTATAGGTCTAGATAGTGCAACATCTAAAAATT
ATGAAATAAATGAAAGTGAAATTATTGATATTGAATAA

Upstream 100 bases:

>100_bases
GAAGAAGAAAAAGATGAAGAAGACGAAGCAGAATAAAATTTTTTATTTTATAAACCCCTTAATCTTTTTTTAATGATTAT
ACTAAATTGAAGGAAGTAAC

Downstream 100 bases:

>100_bases
CTTTCACTTATTTAACTTTTTTTTAACTTGATTTAAAATAGTTTTATCCAAATAAAAAAATTAATCTTAATATATTTATA
CTTTTTTTCATAAAAGTATT

Product: cation transport ATPase

Products: ADP; Orthophosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 705; Mature: 705

Protein sequence:

>705_residues
MKFKIVYDNNKDIIRVRAGRAAFTTSEGYGLSQLLSQKKGIKTVKVSSTNGSIHIKYSGNKNRVFKYLANLKKSDLYEAE
PTTEELSRETNNHYINKILKKIVGRYAAQLFLPTPLNIIKIVYESIPYIVKGIDSLIHMRIDVDLLDATSLAVTLSQGMF
GPAGSIVFLLGLSEILEEYTIEKTKHSLENSLMLNINKVWIETETNEEVQIPFTQLKEKDKVIVRTGTIIPADGVIIKGN
AEINEATMTGESLPVSKNVGKAVFAGTIVENGSITVEVEAINESTRINQIIDLIESSDKLKAGIQSKAEKLADSIVPWNF
AITLLTYIITGSTIKAIAALTVDYSCAIKLATPISIISAMREASEREVVVKGGRYLEAYATADTIIFDKTGTLTKSCPEV
AKVVSLGALSDEELLRQAACIEEHFPHSVATAIVNKAKELGLNHGEELHSEVEYIVAHGIATTLDGKRAVLGSQHFVLED
ENVKITKEKEDIISENVDKYSVIYFAIDRVLEGIICIYDPPRDEAKVVLNKLRSLGIKDIVMLTGDSENAAATTAKLLGI
NHYRSQVLPEDKASIVEEIKEKGKKVIMVGDGINDSPALSAADVSVAMKDSSDLAREVADITLLRPSLNDLITIRLLSQQ
MLDLIHRNYKLILLLNTTFMALGLSGVISPSATSVLHNGSTMLIGLDSATSKNYEINESEIIDIE

Sequences:

>Translated_705_residues
MKFKIVYDNNKDIIRVRAGRAAFTTSEGYGLSQLLSQKKGIKTVKVSSTNGSIHIKYSGNKNRVFKYLANLKKSDLYEAE
PTTEELSRETNNHYINKILKKIVGRYAAQLFLPTPLNIIKIVYESIPYIVKGIDSLIHMRIDVDLLDATSLAVTLSQGMF
GPAGSIVFLLGLSEILEEYTIEKTKHSLENSLMLNINKVWIETETNEEVQIPFTQLKEKDKVIVRTGTIIPADGVIIKGN
AEINEATMTGESLPVSKNVGKAVFAGTIVENGSITVEVEAINESTRINQIIDLIESSDKLKAGIQSKAEKLADSIVPWNF
AITLLTYIITGSTIKAIAALTVDYSCAIKLATPISIISAMREASEREVVVKGGRYLEAYATADTIIFDKTGTLTKSCPEV
AKVVSLGALSDEELLRQAACIEEHFPHSVATAIVNKAKELGLNHGEELHSEVEYIVAHGIATTLDGKRAVLGSQHFVLED
ENVKITKEKEDIISENVDKYSVIYFAIDRVLEGIICIYDPPRDEAKVVLNKLRSLGIKDIVMLTGDSENAAATTAKLLGI
NHYRSQVLPEDKASIVEEIKEKGKKVIMVGDGINDSPALSAADVSVAMKDSSDLAREVADITLLRPSLNDLITIRLLSQQ
MLDLIHRNYKLILLLNTTFMALGLSGVISPSATSVLHNGSTMLIGLDSATSKNYEINESEIIDIE
>Mature_705_residues
MKFKIVYDNNKDIIRVRAGRAAFTTSEGYGLSQLLSQKKGIKTVKVSSTNGSIHIKYSGNKNRVFKYLANLKKSDLYEAE
PTTEELSRETNNHYINKILKKIVGRYAAQLFLPTPLNIIKIVYESIPYIVKGIDSLIHMRIDVDLLDATSLAVTLSQGMF
GPAGSIVFLLGLSEILEEYTIEKTKHSLENSLMLNINKVWIETETNEEVQIPFTQLKEKDKVIVRTGTIIPADGVIIKGN
AEINEATMTGESLPVSKNVGKAVFAGTIVENGSITVEVEAINESTRINQIIDLIESSDKLKAGIQSKAEKLADSIVPWNF
AITLLTYIITGSTIKAIAALTVDYSCAIKLATPISIISAMREASEREVVVKGGRYLEAYATADTIIFDKTGTLTKSCPEV
AKVVSLGALSDEELLRQAACIEEHFPHSVATAIVNKAKELGLNHGEELHSEVEYIVAHGIATTLDGKRAVLGSQHFVLED
ENVKITKEKEDIISENVDKYSVIYFAIDRVLEGIICIYDPPRDEAKVVLNKLRSLGIKDIVMLTGDSENAAATTAKLLGI
NHYRSQVLPEDKASIVEEIKEKGKKVIMVGDGINDSPALSAADVSVAMKDSSDLAREVADITLLRPSLNDLITIRLLSQQ
MLDLIHRNYKLILLLNTTFMALGLSGVISPSATSVLHNGSTMLIGLDSATSKNYEINESEIIDIE

Specific function: Involved In Copper Efflux. [C]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily [H]

Homologues:

Organism=Homo sapiens, GI55743071, Length=579, Percent_Identity=29.3609671848014, Blast_Score=223, Evalue=7e-58,
Organism=Homo sapiens, GI55743073, Length=502, Percent_Identity=30.6772908366534, Blast_Score=208, Evalue=2e-53,
Organism=Homo sapiens, GI115529486, Length=617, Percent_Identity=26.742301458671, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI48762685, Length=140, Percent_Identity=32.1428571428571, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI48762687, Length=140, Percent_Identity=32.1428571428571, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI48762691, Length=140, Percent_Identity=32.1428571428571, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI48762689, Length=140, Percent_Identity=32.1428571428571, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1786691, Length=527, Percent_Identity=29.9810246679317, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI1789879, Length=535, Percent_Identity=29.1588785046729, Blast_Score=193, Evalue=3e-50,
Organism=Escherichia coli, GI1786914, Length=459, Percent_Identity=26.797385620915, Blast_Score=130, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17556548, Length=593, Percent_Identity=26.6441821247892, Blast_Score=161, Evalue=9e-40,
Organism=Saccharomyces cerevisiae, GI6320475, Length=517, Percent_Identity=31.1411992263056, Blast_Score=193, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6319772, Length=598, Percent_Identity=26.7558528428094, Blast_Score=167, Evalue=6e-42,
Organism=Saccharomyces cerevisiae, GI6325221, Length=518, Percent_Identity=24.1312741312741, Blast_Score=124, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6321430, Length=523, Percent_Identity=24.4741873804971, Blast_Score=120, Evalue=6e-28,
Organism=Saccharomyces cerevisiae, GI6321271, Length=194, Percent_Identity=29.3814432989691, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221329854, Length=368, Percent_Identity=28.804347826087, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI281366617, Length=153, Percent_Identity=29.4117647058824, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24668704, Length=153, Percent_Identity=29.4117647058824, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24668708, Length=153, Percent_Identity=29.4117647058824, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24668696, Length=153, Percent_Identity=29.4117647058824, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI161085803, Length=153, Percent_Identity=29.4117647058824, Blast_Score=70, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00702 Hydrolase [H]

EC number: 3.6.3.4 [C]

Molecular weight: Translated: 77208; Mature: 77208

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00154 ATPASE_E1_E2 ; PS01229 COF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFKIVYDNNKDIIRVRAGRAAFTTSEGYGLSQLLSQKKGIKTVKVSSTNGSIHIKYSGN
CEEEEEEECCCCEEEEECCCEEEECCCCCCHHHHHHHHCCCEEEEEECCCCEEEEEECCC
KNRVFKYLANLKKSDLYEAEPTTEELSRETNNHYINKILKKIVGRYAAQLFLPTPLNIIK
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHEECCCCHHHHH
IVYESIPYIVKGIDSLIHMRIDVDLLDATSLAVTLSQGMFGPAGSIVFLLGLSEILEEYT
HHHHHCCHHHHHHHHHEEEEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
IEKTKHSLENSLMLNINKVWIETETNEEVQIPFTQLKEKDKVIVRTGTIIPADGVIIKGN
HHHHHHHHCCCEEEEEEEEEEEECCCCEEECCHHHHCCCCCEEEEECCEECCCCEEEECC
AEINEATMTGESLPVSKNVGKAVFAGTIVENGSITVEVEAINESTRINQIIDLIESSDKL
CCCCCEEECCCCCCCCCCCCCCEEEEEEEECCEEEEEEEECCCCHHHHHHHHHHHCCHHH
KAGIQSKAEKLADSIVPWNFAITLLTYIITGSTIKAIAALTVDYSCAIKLATPISIISAM
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHEEECEEEEEEECCHHHHHHHH
REASEREVVVKGGRYLEAYATADTIIFDKTGTLTKSCPEVAKVVSLGALSDEELLRQAAC
HHCCCCEEEEECCCEEEEEECCCEEEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHH
IEEHFPHSVATAIVNKAKELGLNHGEELHSEVEYIVAHGIATTLDGKRAVLGSQHFVLED
HHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHEECCCCEEEECCCEEEEEC
ENVKITKEKEDIISENVDKYSVIYFAIDRVLEGIICIYDPPRDEAKVVLNKLRSLGIKDI
CCEEEECCHHHHHHCCCCHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHCCCCEE
VMLTGDSENAAATTAKLLGINHYRSQVLPEDKASIVEEIKEKGKKVIMVGDGINDSPALS
EEEECCCCCHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCC
AADVSVAMKDSSDLAREVADITLLRPSLNDLITIRLLSQQMLDLIHRNYKLILLLNTTFM
CCEEEEEECCCHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHH
ALGLSGVISPSATSVLHNGSTMLIGLDSATSKNYEINESEIIDIE
HHCCCCCCCCCHHHHEECCCEEEEEECCCCCCCEECCCCEEEEEC
>Mature Secondary Structure
MKFKIVYDNNKDIIRVRAGRAAFTTSEGYGLSQLLSQKKGIKTVKVSSTNGSIHIKYSGN
CEEEEEEECCCCEEEEECCCEEEECCCCCCHHHHHHHHCCCEEEEEECCCCEEEEEECCC
KNRVFKYLANLKKSDLYEAEPTTEELSRETNNHYINKILKKIVGRYAAQLFLPTPLNIIK
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHEECCCCHHHHH
IVYESIPYIVKGIDSLIHMRIDVDLLDATSLAVTLSQGMFGPAGSIVFLLGLSEILEEYT
HHHHHCCHHHHHHHHHEEEEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
IEKTKHSLENSLMLNINKVWIETETNEEVQIPFTQLKEKDKVIVRTGTIIPADGVIIKGN
HHHHHHHHCCCEEEEEEEEEEEECCCCEEECCHHHHCCCCCEEEEECCEECCCCEEEECC
AEINEATMTGESLPVSKNVGKAVFAGTIVENGSITVEVEAINESTRINQIIDLIESSDKL
CCCCCEEECCCCCCCCCCCCCCEEEEEEEECCEEEEEEEECCCCHHHHHHHHHHHCCHHH
KAGIQSKAEKLADSIVPWNFAITLLTYIITGSTIKAIAALTVDYSCAIKLATPISIISAM
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHEEECEEEEEEECCHHHHHHHH
REASEREVVVKGGRYLEAYATADTIIFDKTGTLTKSCPEVAKVVSLGALSDEELLRQAAC
HHCCCCEEEEECCCEEEEEECCCEEEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHH
IEEHFPHSVATAIVNKAKELGLNHGEELHSEVEYIVAHGIATTLDGKRAVLGSQHFVLED
HHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHEECCCCEEEECCCEEEEEC
ENVKITKEKEDIISENVDKYSVIYFAIDRVLEGIICIYDPPRDEAKVVLNKLRSLGIKDI
CCEEEECCHHHHHHCCCCHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHCCCCEE
VMLTGDSENAAATTAKLLGINHYRSQVLPEDKASIVEEIKEKGKKVIMVGDGINDSPALS
EEEECCCCCHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCC
AADVSVAMKDSSDLAREVADITLLRPSLNDLITIRLLSQQMLDLIHRNYKLILLLNTTFM
CCEEEEEECCCHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHH
ALGLSGVISPSATSVLHNGSTMLIGLDSATSKNYEINESEIIDIE
HHCCCCCCCCCHHHHEECCCEEEEEECCCCCCCEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]