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The map label for this gene is yeeO [C]

Identifier: 84489624

GI number: 84489624

Start: 955434

End: 956798

Strand: Direct

Name: yeeO [C]

Synonym: Msp_0824

Alternate gene names: 84489624

Gene position: 955434-956798 (Clockwise)

Preceding gene: 84489623

Following gene: 84489625

Centisome position: 54.06

GC content: 32.16

Gene sequence:

>1365_bases
ATGAGTAAAACAGATAATATTGAATTAATAAGAGGAGATCCAAAAGTTGCAATAAGAAAATTATCAGTACCTACCATGTT
ATCCATGTTACTTATTATGATGTATAATCTAGCAGATAGTTTATGGGTAGCAGGATTAGGATCTGATGCATTGGCAGCAC
TTGGATTTATAAGTCCACTATTTTTTGTAATAGTAGGAATTGGAAATGGAATAGGAGCTGGTGCAAACTCACTTATAGCT
CGTGCAATAGGACATAAAGATAAAGCTCTAGCAGATAATGCTGCAAGTCACAGTATATTTATTACAATCATACTTTCAAT
AGCATTACCACTAATACTCATACCTCTACTTAGCCCAATTCTCACATTAATGGGTGCAGGACGTTGTGTGAGTATGGGAG
TAGATTATGGTAATGTTGTATTTCTATTCATGATTGTATTTTTATTTGCAAGTGTAGCTTCTGCAATTCTAAGAGCAGAA
GGAGATGTAAATAGATCCATGTATGCCATGGCCATTACTGCAATTTTAAATATAATTATAGATCCAATATTCATTTATGT
ATTACATATGGGAATAGTTGGAGCAGCATGGGCTACTGTACTATCATCACTTATAAGTTGTATTGTAATGGGATACTGGA
TATGGATAAAAAAAGATACTTATCTACGTATCAATAGAAAAGTATTCAACTATGCAAATAAAGTAACTAAAGATATATGT
TCAGTAGCAATACCATCAATGGCTGAAAACATTACAATGTCTGCTTTAATCATGATTATAAATGGAATGCTTACAATTGT
AGCAGGAACTACTGCAGTAGCTGTATATGCTTCAGCTGCAAGAATCAACCAATTTGCAATGATACCTTTATTTGGTATTG
GAACTGCAATGCTTACAGTAACAGGTACAGCATATGGAGCACATGACTATAAAAAACTTAAAGAAGCACATAGATATTCA
ATAATATTAGGATATGGAGTATCAATATTATTATCAATTATAATGTTCTTTGGTTCTGATTACATTGCATTATTATTTGC
ATATACACCAGAGAGTGCACCTCTTGCACCACTTATATCCAATGCATTGAAAATACTATGTCTATTCTTAATAGCAATGC
CTGCAGGTATTATGTCTTCAATGACATTCCAAGGAGTTGGAAAAGGCCTTACATCATTTATAATTACATTATGTAGATCA
ATTATATTTGAAGTAATATTTGGATATGTTATTGGAATTGTACTTGGATTTGGAGAATTTGGAGTATATGCTGGTTTAGT
AATAGGATGTGCTTGTGGTTCATTACTTTCATATGCCTGGTGTAAACTCTTTATTAAGAGACTTAATAAAAACTATACTA
AATGA

Upstream 100 bases:

>100_bases
TGTGAAGAATATGATGGAACAAAGGAAGAATTATTGAATAATCTACGAAAAATGACATTAACCTCATTTAATATGATAAA
TGATAACCGAGATAATATTT

Downstream 100 bases:

>100_bases
GATTTTTTATAAAATCTCAATTTTTTTTGAAAATTAGATTTCACATTATAAACTACATTATTCTAGATTTAATTATTATA
AAAATATTAAATAGTATATC

Product: Na+-driven multidrug efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MSKTDNIELIRGDPKVAIRKLSVPTMLSMLLIMMYNLADSLWVAGLGSDALAALGFISPLFFVIVGIGNGIGAGANSLIA
RAIGHKDKALADNAASHSIFITIILSIALPLILIPLLSPILTLMGAGRCVSMGVDYGNVVFLFMIVFLFASVASAILRAE
GDVNRSMYAMAITAILNIIIDPIFIYVLHMGIVGAAWATVLSSLISCIVMGYWIWIKKDTYLRINRKVFNYANKVTKDIC
SVAIPSMAENITMSALIMIINGMLTIVAGTTAVAVYASAARINQFAMIPLFGIGTAMLTVTGTAYGAHDYKKLKEAHRYS
IILGYGVSILLSIIMFFGSDYIALLFAYTPESAPLAPLISNALKILCLFLIAMPAGIMSSMTFQGVGKGLTSFIITLCRS
IIFEVIFGYVIGIVLGFGEFGVYAGLVIGCACGSLLSYAWCKLFIKRLNKNYTK

Sequences:

>Translated_454_residues
MSKTDNIELIRGDPKVAIRKLSVPTMLSMLLIMMYNLADSLWVAGLGSDALAALGFISPLFFVIVGIGNGIGAGANSLIA
RAIGHKDKALADNAASHSIFITIILSIALPLILIPLLSPILTLMGAGRCVSMGVDYGNVVFLFMIVFLFASVASAILRAE
GDVNRSMYAMAITAILNIIIDPIFIYVLHMGIVGAAWATVLSSLISCIVMGYWIWIKKDTYLRINRKVFNYANKVTKDIC
SVAIPSMAENITMSALIMIINGMLTIVAGTTAVAVYASAARINQFAMIPLFGIGTAMLTVTGTAYGAHDYKKLKEAHRYS
IILGYGVSILLSIIMFFGSDYIALLFAYTPESAPLAPLISNALKILCLFLIAMPAGIMSSMTFQGVGKGLTSFIITLCRS
IIFEVIFGYVIGIVLGFGEFGVYAGLVIGCACGSLLSYAWCKLFIKRLNKNYTK
>Mature_453_residues
SKTDNIELIRGDPKVAIRKLSVPTMLSMLLIMMYNLADSLWVAGLGSDALAALGFISPLFFVIVGIGNGIGAGANSLIAR
AIGHKDKALADNAASHSIFITIILSIALPLILIPLLSPILTLMGAGRCVSMGVDYGNVVFLFMIVFLFASVASAILRAEG
DVNRSMYAMAITAILNIIIDPIFIYVLHMGIVGAAWATVLSSLISCIVMGYWIWIKKDTYLRINRKVFNYANKVTKDICS
VAIPSMAENITMSALIMIINGMLTIVAGTTAVAVYASAARINQFAMIPLFGIGTAMLTVTGTAYGAHDYKKLKEAHRYSI
ILGYGVSILLSIIMFFGSDYIALLFAYTPESAPLAPLISNALKILCLFLIAMPAGIMSSMTFQGVGKGLTSFIITLCRSI
IFEVIFGYVIGIVLGFGEFGVYAGLVIGCACGSLLSYAWCKLFIKRLNKNYTK

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=438, Percent_Identity=22.6027397260274, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 48758; Mature: 48627

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTDNIELIRGDPKVAIRKLSVPTMLSMLLIMMYNLADSLWVAGLGSDALAALGFISPL
CCCCCCEEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
FFVIVGIGNGIGAGANSLIARAIGHKDKALADNAASHSIFITIILSIALPLILIPLLSPI
HHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LTLMGAGRCVSMGVDYGNVVFLFMIVFLFASVASAILRAEGDVNRSMYAMAITAILNIII
HHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
DPIFIYVLHMGIVGAAWATVLSSLISCIVMGYWIWIKKDTYLRINRKVFNYANKVTKDIC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEHHHHHHHHHHHHHHHH
SVAIPSMAENITMSALIMIINGMLTIVAGTTAVAVYASAARINQFAMIPLFGIGTAMLTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
TGTAYGAHDYKKLKEAHRYSIILGYGVSILLSIIMFFGSDYIALLFAYTPESAPLAPLIS
ECCCCCHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHCCCHHHHHEEECCCCCCHHHHHH
NALKILCLFLIAMPAGIMSSMTFQGVGKGLTSFIITLCRSIIFEVIFGYVIGIVLGFGEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVYAGLVIGCACGSLLSYAWCKLFIKRLNKNYTK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SKTDNIELIRGDPKVAIRKLSVPTMLSMLLIMMYNLADSLWVAGLGSDALAALGFISPL
CCCCCEEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
FFVIVGIGNGIGAGANSLIARAIGHKDKALADNAASHSIFITIILSIALPLILIPLLSPI
HHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LTLMGAGRCVSMGVDYGNVVFLFMIVFLFASVASAILRAEGDVNRSMYAMAITAILNIII
HHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
DPIFIYVLHMGIVGAAWATVLSSLISCIVMGYWIWIKKDTYLRINRKVFNYANKVTKDIC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEHHHHHHHHHHHHHHHH
SVAIPSMAENITMSALIMIINGMLTIVAGTTAVAVYASAARINQFAMIPLFGIGTAMLTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
TGTAYGAHDYKKLKEAHRYSIILGYGVSILLSIIMFFGSDYIALLFAYTPESAPLAPLIS
ECCCCCHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHCCCHHHHHEEECCCCCCHHHHHH
NALKILCLFLIAMPAGIMSSMTFQGVGKGLTSFIITLCRSIIFEVIFGYVIGIVLGFGEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVYAGLVIGCACGSLLSYAWCKLFIKRLNKNYTK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]