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The map label for this gene is mntH [H]

Identifier: 83721670

GI number: 83721670

Start: 3068770

End: 3070128

Strand: Reverse

Name: mntH [H]

Synonym: BTH_I2687

Alternate gene names: 83721670

Gene position: 3070128-3068770 (Counterclockwise)

Preceding gene: 83720457

Following gene: 83720162

Centisome position: 80.6

GC content: 66.37

Gene sequence:

>1359_bases
ATGCGTAAAATGACCGCCACGCACACAGGCCCTCGAACATCTCCCATGCCGCTCCCCACCGTCCCCACGGCGCCGTTTTG
CCCCGCAGAAGTCAAAGGCAGCATCACGATCGACGCCGGCGTCTCCGGTCTCGCCAAACTGCGCCGCTTCGCCGGCCCGG
GCCTGCTCGTGGCGATCGGTTACATGGACCCCGGCAATTGGGCGACCGACATTCAGGCCGGCTCGCAGTTCGGCTACGCG
CTGTTGTGGGTCGTCGTGTTTTCGAGCGTCGCCGCGATCTTCCTGCAGATGCTCGCTGCGCGGCTCGGGCTCGTCGCCGG
TCGCGATCTCGCGCAGGCGAGCTACGAGCGTTACGGGCCGTTCGGCCGGATCGTGCAGTGGGTCACGGCCGAGGTATCGA
TCATCGCGTGCGACATCGCCGAGGTGCTCGGCTGCGCGCTGGCGTTCAAGCTGCTGCTCGGCGTGCCGCTCGCGTGGGGC
ATCGTTCTCACCGCGCTCGACACGATGATCGTCCTCGGTTTGCAGGGCAAGGGGTTCAGGCAGGTCGAGGCGATCGTGCT
CGGGCTGATCGGCACGATGGCGTTCTGCTTCGTCGCGCAGGTCGCGATGGTGCCGCCCGATTGGCGTGCCGTGCTGCATG
GCCTTGCGCCCGGCTTGCCGGGCCACGACCGCAAGGATGCGGTCGTGCTCGCGCTGGGCATCGTCGGTGCGACCATCATG
CCGCACAACCTGTATCTGCATTCGTCTGTCGTGCAGACGCGGCGCGTCGTCGGCGGCGTGGGCGACGTAATCAAGGAAAC
GCTCGCGATGGTTCGCATCGACACGTGGATATCGCTCGCCGTCGCGATGCTCGTCAACGCGGCGATCTTGATCTTGGCCG
GCGCGGCGTTCCATGCAAGCGGTCAGACTGGCGTCGTCGACATCGAGCAGGCCTACAAGCTGATCACGCCGATCGTCGGC
GGCGCGGCCGCGTGGCTGCTCGGCATCGCGCTCCTCGCGTCGGGCCAGAGCTCGACGCTGACCGGCACGATCGCCGGGCA
GGTCATCATGGATGGCTTCCTGCGCATGAAGATCCCGTGTTACCAACGCAGGCTGATCACGCGCGGGCTCGCGCTCATGC
CGGCGCTCGTCGGCGTGCTGTGGCTCGGCGACGGCGCGGTCGGGCGGCTGCTGGTCTGGAGCCAGGTGCTGTTGAGCCTG
CAATTGCCGTTTGCGATGTGGCCGCTGATCCGGTCAGTCGGTGATCGATCGGTCATGCGCGATTACACGATCGGGCGCGG
AGCGAAGATCATCGCATGGGCGCTTTTCGTGTTGATTAGCGGAACGAATCTGTTGCTGGTCGCGGGTTTCGCCGGTTGA

Upstream 100 bases:

>100_bases
GCGGCCATCCCGCGAATTTCCCGGTGGGGTGCCATTTTCGCGAAGCCCGCATCACTACCGCTCGACGTGCGTTGACGATC
AGGGTGGGCGGTCGTCGCGA

Downstream 100 bases:

>100_bases
TGCGATTCGCATTGTCGCGAGCCGATGAGTCGCGGTGTGTCAGGCGAGCGCACGTATCGGACCGTCGGGCCGAGGCATCC
GCGTTCACAGGCGAGCCATC

Product: manganese transport protein MntH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MRKMTATHTGPRTSPMPLPTVPTAPFCPAEVKGSITIDAGVSGLAKLRRFAGPGLLVAIGYMDPGNWATDIQAGSQFGYA
LLWVVVFSSVAAIFLQMLAARLGLVAGRDLAQASYERYGPFGRIVQWVTAEVSIIACDIAEVLGCALAFKLLLGVPLAWG
IVLTALDTMIVLGLQGKGFRQVEAIVLGLIGTMAFCFVAQVAMVPPDWRAVLHGLAPGLPGHDRKDAVVLALGIVGATIM
PHNLYLHSSVVQTRRVVGGVGDVIKETLAMVRIDTWISLAVAMLVNAAILILAGAAFHASGQTGVVDIEQAYKLITPIVG
GAAAWLLGIALLASGQSSTLTGTIAGQVIMDGFLRMKIPCYQRRLITRGLALMPALVGVLWLGDGAVGRLLVWSQVLLSL
QLPFAMWPLIRSVGDRSVMRDYTIGRGAKIIAWALFVLISGTNLLLVAGFAG

Sequences:

>Translated_452_residues
MRKMTATHTGPRTSPMPLPTVPTAPFCPAEVKGSITIDAGVSGLAKLRRFAGPGLLVAIGYMDPGNWATDIQAGSQFGYA
LLWVVVFSSVAAIFLQMLAARLGLVAGRDLAQASYERYGPFGRIVQWVTAEVSIIACDIAEVLGCALAFKLLLGVPLAWG
IVLTALDTMIVLGLQGKGFRQVEAIVLGLIGTMAFCFVAQVAMVPPDWRAVLHGLAPGLPGHDRKDAVVLALGIVGATIM
PHNLYLHSSVVQTRRVVGGVGDVIKETLAMVRIDTWISLAVAMLVNAAILILAGAAFHASGQTGVVDIEQAYKLITPIVG
GAAAWLLGIALLASGQSSTLTGTIAGQVIMDGFLRMKIPCYQRRLITRGLALMPALVGVLWLGDGAVGRLLVWSQVLLSL
QLPFAMWPLIRSVGDRSVMRDYTIGRGAKIIAWALFVLISGTNLLLVAGFAG
>Mature_452_residues
MRKMTATHTGPRTSPMPLPTVPTAPFCPAEVKGSITIDAGVSGLAKLRRFAGPGLLVAIGYMDPGNWATDIQAGSQFGYA
LLWVVVFSSVAAIFLQMLAARLGLVAGRDLAQASYERYGPFGRIVQWVTAEVSIIACDIAEVLGCALAFKLLLGVPLAWG
IVLTALDTMIVLGLQGKGFRQVEAIVLGLIGTMAFCFVAQVAMVPPDWRAVLHGLAPGLPGHDRKDAVVLALGIVGATIM
PHNLYLHSSVVQTRRVVGGVGDVIKETLAMVRIDTWISLAVAMLVNAAILILAGAAFHASGQTGVVDIEQAYKLITPIVG
GAAAWLLGIALLASGQSSTLTGTIAGQVIMDGFLRMKIPCYQRRLITRGLALMPALVGVLWLGDGAVGRLLVWSQVLLSL
QLPFAMWPLIRSVGDRSVMRDYTIGRGAKIIAWALFVLISGTNLLLVAGFAG

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family [H]

Homologues:

Organism=Homo sapiens, GI109255241, Length=438, Percent_Identity=35.3881278538813, Blast_Score=240, Evalue=2e-63,
Organism=Homo sapiens, GI295293167, Length=428, Percent_Identity=35.0467289719626, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI295293178, Length=428, Percent_Identity=35.0467289719626, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI295293175, Length=428, Percent_Identity=35.0467289719626, Blast_Score=213, Evalue=3e-55,
Organism=Homo sapiens, GI295293173, Length=428, Percent_Identity=35.0467289719626, Blast_Score=213, Evalue=3e-55,
Organism=Homo sapiens, GI10835169, Length=428, Percent_Identity=35.0467289719626, Blast_Score=213, Evalue=3e-55,
Organism=Homo sapiens, GI295293171, Length=428, Percent_Identity=35.0467289719626, Blast_Score=213, Evalue=3e-55,
Organism=Homo sapiens, GI295293169, Length=428, Percent_Identity=35.0467289719626, Blast_Score=213, Evalue=3e-55,
Organism=Escherichia coli, GI1788736, Length=401, Percent_Identity=39.9002493765586, Blast_Score=265, Evalue=4e-72,
Organism=Caenorhabditis elegans, GI71999499, Length=439, Percent_Identity=32.3462414578588, Blast_Score=223, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI17569473, Length=378, Percent_Identity=34.6560846560847, Blast_Score=218, Evalue=4e-57,
Organism=Caenorhabditis elegans, GI193210616, Length=435, Percent_Identity=31.9540229885057, Blast_Score=217, Evalue=8e-57,
Organism=Caenorhabditis elegans, GI71993856, Length=216, Percent_Identity=38.8888888888889, Blast_Score=153, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6323062, Length=396, Percent_Identity=37.3737373737374, Blast_Score=236, Evalue=8e-63,
Organism=Saccharomyces cerevisiae, GI6321841, Length=417, Percent_Identity=37.6498800959233, Blast_Score=224, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6324450, Length=423, Percent_Identity=32.387706855792, Blast_Score=212, Evalue=1e-55,
Organism=Drosophila melanogaster, GI24648607, Length=461, Percent_Identity=32.1041214750542, Blast_Score=224, Evalue=6e-59,
Organism=Drosophila melanogaster, GI281362176, Length=461, Percent_Identity=32.1041214750542, Blast_Score=224, Evalue=6e-59,
Organism=Drosophila melanogaster, GI24648609, Length=461, Percent_Identity=32.1041214750542, Blast_Score=224, Evalue=6e-59,
Organism=Drosophila melanogaster, GI45553443, Length=439, Percent_Identity=31.8906605922551, Blast_Score=213, Evalue=3e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 47680; Mature: 47680

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKMTATHTGPRTSPMPLPTVPTAPFCPAEVKGSITIDAGVSGLAKLRRFAGPGLLVAIG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHCCCCEEEEEE
YMDPGNWATDIQAGSQFGYALLWVVVFSSVAAIFLQMLAARLGLVAGRDLAQASYERYGP
ECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
FGRIVQWVTAEVSIIACDIAEVLGCALAFKLLLGVPLAWGIVLTALDTMIVLGLQGKGFR
HHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHEECCCCCCHH
QVEAIVLGLIGTMAFCFVAQVAMVPPDWRAVLHGLAPGLPGHDRKDAVVLALGIVGATIM
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHEEHHHHHHHHHC
PHNLYLHSSVVQTRRVVGGVGDVIKETLAMVRIDTWISLAVAMLVNAAILILAGAAFHAS
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GQTGVVDIEQAYKLITPIVGGAAAWLLGIALLASGQSSTLTGTIAGQVIMDGFLRMKIPC
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHCCCH
YQRRLITRGLALMPALVGVLWLGDGAVGRLLVWSQVLLSLQLPFAMWPLIRSVGDRSVMR
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHH
DYTIGRGAKIIAWALFVLISGTNLLLVAGFAG
HCCCCCCHHHHHHHHHHHHCCCCEEEEEECCC
>Mature Secondary Structure
MRKMTATHTGPRTSPMPLPTVPTAPFCPAEVKGSITIDAGVSGLAKLRRFAGPGLLVAIG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHCCCCEEEEEE
YMDPGNWATDIQAGSQFGYALLWVVVFSSVAAIFLQMLAARLGLVAGRDLAQASYERYGP
ECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
FGRIVQWVTAEVSIIACDIAEVLGCALAFKLLLGVPLAWGIVLTALDTMIVLGLQGKGFR
HHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHEECCCCCCHH
QVEAIVLGLIGTMAFCFVAQVAMVPPDWRAVLHGLAPGLPGHDRKDAVVLALGIVGATIM
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHEEHHHHHHHHHC
PHNLYLHSSVVQTRRVVGGVGDVIKETLAMVRIDTWISLAVAMLVNAAILILAGAAFHAS
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GQTGVVDIEQAYKLITPIVGGAAAWLLGIALLASGQSSTLTGTIAGQVIMDGFLRMKIPC
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHCCCH
YQRRLITRGLALMPALVGVLWLGDGAVGRLLVWSQVLLSLQLPFAMWPLIRSVGDRSVMR
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHH
DYTIGRGAKIIAWALFVLISGTNLLLVAGFAG
HCCCCCCHHHHHHHHHHHHCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]