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The map label for this gene is murB [H]

Identifier: 83721636

GI number: 83721636

Start: 840249

End: 841442

Strand: Direct

Name: murB [H]

Synonym: BTH_I0731

Alternate gene names: 83721636

Gene position: 840249-841442 (Clockwise)

Preceding gene: 83719932

Following gene: 83720604

Centisome position: 22.06

GC content: 69.85

Gene sequence:

>1194_bases
ATGGCATGGCATTCTCCTGTAGAGCGTGCCGCACGCGGCCTGCGTACGGGCACTCGCTATAATTGCGGGCTGACCGCCAT
TTTACCGGCGCCCCCTACATTTGCCCAAGGCCGCGGACTTGACCGCGCGCCGGCGCAACCGCGAATGCCGATGTCCCGTC
CCGATTCTTCCGTCCAATTGCTTTCCGACTATTCGCTGCGTGCGCACAACACGTTCGGCTTCGACGTGCGCGCGCGCGTC
GCGGCGCGGATCGGCTCGCCCGAGCAGTTCGCGTCGCTCGCGCGCGATCCGCGCGTCGCGGGGCTCGATGCGCTCGTGCT
CGGCGGCGGCAGCAATGTGGTGTTCACGCGCGACTTCGACGGCCTCGTGCTGCTCGACGAGATCCGTGGCCGCGCGCTCG
CGCGCGAGGACGACGACGCCTGGTACGTCGAGGCGGGCGGCGGCGAGAACTGGCACGCGTTCGTCGAGTGGACGCTCGCC
GAAGGCATGCCCGGGCTCGAGAATCTCGCGCTGATTCCGGGCACGGTCGGCGCGGCGCCGATCCAGAACATCGGCGCGTA
CGGGATCGAGATGAAGGAGCGTTTCGCGTCGCTGCGCGCGGTCGAGCTCGCGACGGGCGAGATCGTCGAGTTCGACGCGG
CGCGCTGCGCGTTCGGTTATCGAGACAGTTTCTTCAAGCGGGAAGGGCGCGGCCGTTTCGCGATCGTGTCGGTGACGTTC
CGGTTGCCGAAGGTGTGGGCGCCGCGGCTCGGCTACGCGGACGTCGCGCGTGAGCTCGCCGCGCGTGGAATCGACGCGAG
CCGCGCGAGCGCGCGCGACGTGTTCGACGCGGTCGTCGCGATCCGGCGCGCGAAGCTGCCCGATCCGCTCGAGCTGGGCA
ATGCGGGCAGCTTCTTCAAGAATCCGGTGATCGACGCACACGCGTATGCCGCGCTGCGCGCGCGCGAGCCCGACGTCGCG
TCGTATCCGCAGCCGGATGGCCGGATGAAGCTCGCGGCCGGCTGGCTGATCGATCGCTGCGGATGGAAGGGGCGCGCCCT
TGGCGCGGCGGCTGTCCACGACCGGCAGGCGCTCGTGCTCGTCAATCGCGGCGGCGCGTCCGGCGCTGACGTGCTCGCGC
TCGCGCGTGCGATCCAGCGCGACGTGCTCGAACGCTTCGGCGTCGAACTGGAGATGGAGCCGGTATGCCTGTAG

Upstream 100 bases:

>100_bases
TCGGAGCCCTTGAAGTCGAAGCGGGTCGAAATTTCCTTGTTCGACTGCTCGACTGCGTTTTTCACTTCGATCATGTTCGC
TTCGGAAACGACGTCGAACG

Downstream 100 bases:

>100_bases
GCGGCTTGCGGCCGCCCGCAGCGGCTGCATCGACGGTCTAGCGATAAAAAAACCTCGCTGTCGATCAGCGAGGTTTCTTC
TTGCGCCGAAGGCGAGTGCG

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MAWHSPVERAARGLRTGTRYNCGLTAILPAPPTFAQGRGLDRAPAQPRMPMSRPDSSVQLLSDYSLRAHNTFGFDVRARV
AARIGSPEQFASLARDPRVAGLDALVLGGGSNVVFTRDFDGLVLLDEIRGRALAREDDDAWYVEAGGGENWHAFVEWTLA
EGMPGLENLALIPGTVGAAPIQNIGAYGIEMKERFASLRAVELATGEIVEFDAARCAFGYRDSFFKREGRGRFAIVSVTF
RLPKVWAPRLGYADVARELAARGIDASRASARDVFDAVVAIRRAKLPDPLELGNAGSFFKNPVIDAHAYAALRAREPDVA
SYPQPDGRMKLAAGWLIDRCGWKGRALGAAAVHDRQALVLVNRGGASGADVLALARAIQRDVLERFGVELEMEPVCL

Sequences:

>Translated_397_residues
MAWHSPVERAARGLRTGTRYNCGLTAILPAPPTFAQGRGLDRAPAQPRMPMSRPDSSVQLLSDYSLRAHNTFGFDVRARV
AARIGSPEQFASLARDPRVAGLDALVLGGGSNVVFTRDFDGLVLLDEIRGRALAREDDDAWYVEAGGGENWHAFVEWTLA
EGMPGLENLALIPGTVGAAPIQNIGAYGIEMKERFASLRAVELATGEIVEFDAARCAFGYRDSFFKREGRGRFAIVSVTF
RLPKVWAPRLGYADVARELAARGIDASRASARDVFDAVVAIRRAKLPDPLELGNAGSFFKNPVIDAHAYAALRAREPDVA
SYPQPDGRMKLAAGWLIDRCGWKGRALGAAAVHDRQALVLVNRGGASGADVLALARAIQRDVLERFGVELEMEPVCL
>Mature_396_residues
AWHSPVERAARGLRTGTRYNCGLTAILPAPPTFAQGRGLDRAPAQPRMPMSRPDSSVQLLSDYSLRAHNTFGFDVRARVA
ARIGSPEQFASLARDPRVAGLDALVLGGGSNVVFTRDFDGLVLLDEIRGRALAREDDDAWYVEAGGGENWHAFVEWTLAE
GMPGLENLALIPGTVGAAPIQNIGAYGIEMKERFASLRAVELATGEIVEFDAARCAFGYRDSFFKREGRGRFAIVSVTFR
LPKVWAPRLGYADVARELAARGIDASRASARDVFDAVVAIRRAKLPDPLELGNAGSFFKNPVIDAHAYAALRAREPDVAS
YPQPDGRMKLAAGWLIDRCGWKGRALGAAAVHDRQALVLVNRGGASGADVLALARAIQRDVLERFGVELEMEPVCL

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=331, Percent_Identity=49.2447129909366, Blast_Score=322, Evalue=2e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 42980; Mature: 42849

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWHSPVERAARGLRTGTRYNCGLTAILPAPPTFAQGRGLDRAPAQPRMPMSRPDSSVQL
CCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
LSDYSLRAHNTFGFDVRARVAARIGSPEQFASLARDPRVAGLDALVLGGGSNVVFTRDFD
HHCCCEEECCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCEEEEEECCCCEEEEECCC
GLVLLDEIRGRALAREDDDAWYVEAGGGENWHAFVEWTLAEGMPGLENLALIPGTVGAAP
CEEEEEHHCCCCCCCCCCCEEEEECCCCCCEEEEEEEEECCCCCCCCCEEECCCCCCCCC
IQNIGAYGIEMKERFASLRAVELATGEIVEFDAARCAFGYRDSFFKREGRGRFAIVSVTF
HHHCCCCCHHHHHHHHHHEEEEECCCCEEEECCHHHHCCCHHHHHHHCCCCCEEEEEEEE
RLPKVWAPRLGYADVARELAARGIDASRASARDVFDAVVAIRRAKLPDPLELGNAGSFFK
ECCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHC
NPVIDAHAYAALRAREPDVASYPQPDGRMKLAAGWLIDRCGWKGRALGAAAVHDRQALVL
CCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEECHHHHHCCCCCCCCCHHEECCCEEEEE
VNRGGASGADVLALARAIQRDVLERFGVELEMEPVCL
EECCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCC
>Mature Secondary Structure 
AWHSPVERAARGLRTGTRYNCGLTAILPAPPTFAQGRGLDRAPAQPRMPMSRPDSSVQL
CCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
LSDYSLRAHNTFGFDVRARVAARIGSPEQFASLARDPRVAGLDALVLGGGSNVVFTRDFD
HHCCCEEECCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCEEEEEECCCCEEEEECCC
GLVLLDEIRGRALAREDDDAWYVEAGGGENWHAFVEWTLAEGMPGLENLALIPGTVGAAP
CEEEEEHHCCCCCCCCCCCEEEEECCCCCCEEEEEEEEECCCCCCCCCEEECCCCCCCCC
IQNIGAYGIEMKERFASLRAVELATGEIVEFDAARCAFGYRDSFFKREGRGRFAIVSVTF
HHHCCCCCHHHHHHHHHHEEEEECCCCEEEECCHHHHCCCHHHHHHHCCCCCEEEEEEEE
RLPKVWAPRLGYADVARELAARGIDASRASARDVFDAVVAIRRAKLPDPLELGNAGSFFK
ECCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHC
NPVIDAHAYAALRAREPDVASYPQPDGRMKLAAGWLIDRCGWKGRALGAAAVHDRQALVL
CCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEECHHHHHCCCCCCCCCHHEECCCEEEEE
VNRGGASGADVLALARAIQRDVLERFGVELEMEPVCL
EECCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA