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The map label for this gene is cbl [H]

Identifier: 83721634

GI number: 83721634

Start: 927159

End: 928100

Strand: Reverse

Name: cbl [H]

Synonym: BTH_I0813

Alternate gene names: 83721634

Gene position: 928100-927159 (Counterclockwise)

Preceding gene: 83719872

Following gene: 83719798

Centisome position: 24.36

GC content: 64.76

Gene sequence:

>942_bases
ATGAACCTGCACCAATTTCGCTTCGTGCGCGAGGCCGTCCGGCAGAATTTCAATCTCACGGAAGCCGCGAAAGCGCTGTA
CACGTCGCAGCCGGGGGTATCGAAAGCCATCATCGAGCTTGAGGACGAACTCGGCGTCGAGATCTTCACGCGCCACGGCA
AACGCGTGCGCTCCCTGACCGAACCGGGGAGGATCATCCTCGCATCGGTCGAGCGGATCCTCCAGGAGGTCGAGAGCCTT
AAAAGGGTCGGAAAGGACTACGCGGCGCAGGACCAGGGCAACCTGACGATCGCCGCGACGCACACGCAGGCCCGCTACTC
GCTGCCGGCCGCGATCGCCGAGTTCAAGAAACGCTTCCCGAAGGTGCATCTGTCGATCCTGCAGGGCAGCCCGACGCAGG
TCGCCGAAATGGTGATCCACGATCAGGCGGACCTCGCGATCGCGACGGAGGCGATCGCCGACTACAAGGAACTCGTGTCG
CTGCCCTGCTTCCAGTGGCACCACACGGCCGTCGTGCCGGCCGATCACCCGCTCCTCGAGCGCAAGCCGCTGTCGCTCGA
CGATCTCGCGCAGTTTCCGCTCATCACGTACGACGACGCGTTCGCGGGCCGCAAGAAGATCAACCAGGCGTTCGCGCTGC
ATCGCCTCACGCCCGACATCGTGCTCGAGGCGATCGACGCGGACGTGATCAAGACCTACGTCGAGCTCGGGCTCGGCGTC
GGCATCTTGGCCGACGTCGCGTTCAACCCGGAGCGCGACCGCAATCTGCGCGCGATTCCGGTCGGGCACCTGTTCGGCAG
CAACGTGACGCGCGTCGCGCTCAAGCAGGGCGCGTATCTGCGCGGTTATATCTACACGCTCGTCGAGCTGCTGTCGCCGA
CGCTGAACCGCAAGCTCGTCGAGACTGCGCTCAAGGGCGAGGCCGAGACCTACGAGCTGTGA

Upstream 100 bases:

>100_bases
TTACAGATATCCATATTTGAAAAACACGGGGCAATCGTAATAAACTCCCCTTATATTTCAAACGACTAAAAAATTCTGTT
GATATGCGGAAGGGTTATAA

Downstream 100 bases:

>100_bases
CGCCGGGCCGCGCGCGCTGCCCGCCGGCCGGCCTTCCGGCGAAGCGGGCGACGCTCGCGTTCGTCGTCGCACGCGAGGCA
AAATACGGGCGCGACCCGGT

Product: transcriptional regulator CysB-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MNLHQFRFVREAVRQNFNLTEAAKALYTSQPGVSKAIIELEDELGVEIFTRHGKRVRSLTEPGRIILASVERILQEVESL
KRVGKDYAAQDQGNLTIAATHTQARYSLPAAIAEFKKRFPKVHLSILQGSPTQVAEMVIHDQADLAIATEAIADYKELVS
LPCFQWHHTAVVPADHPLLERKPLSLDDLAQFPLITYDDAFAGRKKINQAFALHRLTPDIVLEAIDADVIKTYVELGLGV
GILADVAFNPERDRNLRAIPVGHLFGSNVTRVALKQGAYLRGYIYTLVELLSPTLNRKLVETALKGEAETYEL

Sequences:

>Translated_313_residues
MNLHQFRFVREAVRQNFNLTEAAKALYTSQPGVSKAIIELEDELGVEIFTRHGKRVRSLTEPGRIILASVERILQEVESL
KRVGKDYAAQDQGNLTIAATHTQARYSLPAAIAEFKKRFPKVHLSILQGSPTQVAEMVIHDQADLAIATEAIADYKELVS
LPCFQWHHTAVVPADHPLLERKPLSLDDLAQFPLITYDDAFAGRKKINQAFALHRLTPDIVLEAIDADVIKTYVELGLGV
GILADVAFNPERDRNLRAIPVGHLFGSNVTRVALKQGAYLRGYIYTLVELLSPTLNRKLVETALKGEAETYEL
>Mature_313_residues
MNLHQFRFVREAVRQNFNLTEAAKALYTSQPGVSKAIIELEDELGVEIFTRHGKRVRSLTEPGRIILASVERILQEVESL
KRVGKDYAAQDQGNLTIAATHTQARYSLPAAIAEFKKRFPKVHLSILQGSPTQVAEMVIHDQADLAIATEAIADYKELVS
LPCFQWHHTAVVPADHPLLERKPLSLDDLAQFPLITYDDAFAGRKKINQAFALHRLTPDIVLEAIDADVIKTYVELGLGV
GILADVAFNPERDRNLRAIPVGHLFGSNVTRVALKQGAYLRGYIYTLVELLSPTLNRKLVETALKGEAETYEL

Specific function: May be an accessory regulatory protein within the cys regulon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788296, Length=308, Percent_Identity=45.4545454545455, Blast_Score=291, Evalue=5e-80,
Organism=Escherichia coli, GI1787530, Length=304, Percent_Identity=44.4078947368421, Blast_Score=287, Evalue=7e-79,
Organism=Escherichia coli, GI157672245, Length=213, Percent_Identity=32.8638497652582, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788481, Length=247, Percent_Identity=27.9352226720648, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI145693105, Length=245, Percent_Identity=26.530612244898, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788887, Length=249, Percent_Identity=28.5140562248996, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790399, Length=255, Percent_Identity=24.7058823529412, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1789204, Length=242, Percent_Identity=27.2727272727273, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1787879, Length=259, Percent_Identity=26.2548262548263, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787601, Length=149, Percent_Identity=28.8590604026846, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788297, Length=252, Percent_Identity=24.2063492063492, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87082132, Length=147, Percent_Identity=25.8503401360544, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34898; Mature: 34898

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHQFRFVREAVRQNFNLTEAAKALYTSQPGVSKAIIELEDELGVEIFTRHGKRVRSLT
CCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHCCHHHHHHC
EPGRIILASVERILQEVESLKRVGKDYAAQDQGNLTIAATHTQARYSLPAAIAEFKKRFP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCC
KVHLSILQGSPTQVAEMVIHDQADLAIATEAIADYKELVSLPCFQWHHTAVVPADHPLLE
CEEEHEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCC
RKPLSLDDLAQFPLITYDDAFAGRKKINQAFALHRLTPDIVLEAIDADVIKTYVELGLGV
CCCCCHHHHHHCCEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCH
GILADVAFNPERDRNLRAIPVGHLFGSNVTRVALKQGAYLRGYIYTLVELLSPTLNRKLV
HHHHHHCCCCCCCCCCEEEEEHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHH
ETALKGEAETYEL
HHHHCCCCCCCCC
>Mature Secondary Structure
MNLHQFRFVREAVRQNFNLTEAAKALYTSQPGVSKAIIELEDELGVEIFTRHGKRVRSLT
CCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHCCHHHHHHC
EPGRIILASVERILQEVESLKRVGKDYAAQDQGNLTIAATHTQARYSLPAAIAEFKKRFP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCC
KVHLSILQGSPTQVAEMVIHDQADLAIATEAIADYKELVSLPCFQWHHTAVVPADHPLLE
CEEEHEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCC
RKPLSLDDLAQFPLITYDDAFAGRKKINQAFALHRLTPDIVLEAIDADVIKTYVELGLGV
CCCCCHHHHHHCCEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCH
GILADVAFNPERDRNLRAIPVGHLFGSNVTRVALKQGAYLRGYIYTLVELLSPTLNRKLV
HHHHHHCCCCCCCCCCEEEEEHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHH
ETALKGEAETYEL
HHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8529872; 9097040; 9278503 [H]