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The map label for this gene is plsC [H]

Identifier: 83721584

GI number: 83721584

Start: 663583

End: 664362

Strand: Reverse

Name: plsC [H]

Synonym: BTH_I0582

Alternate gene names: 83721584

Gene position: 664362-663583 (Counterclockwise)

Preceding gene: 83720323

Following gene: 83718890

Centisome position: 17.44

GC content: 67.56

Gene sequence:

>780_bases
ATGCGCTTCGTCCGCTCCCTGCTGCTGCTCGTCTATTTCGTCGTCTACACGGTGCCGTACGCAACCGCGTGCTTCATCGC
GTTCCCGTTCATGCGCCCGAACGCGCGCTACTGGATGGCGGTCGGCTGGTGCAAGTCGACGCTGTTCGTCGCGCGCTGGC
TGAACGGCATCCGGTATCGCATCGAAGGCTACGAGAACCTGCCCGACGGCCCGGCCGTGCTGCTGCCGAAGCATCAGTCC
GCGTGGGAAACGATCGCGCTGCCCGCGCTGATGCCGAAGCCGCTCTGCTACGTGTTCAAGCGCGAGCTGCTGTACGTGCC
GTTCTTCGGCTGGGCGCTCGGGATGCTGCACATGGTCCACATCAATCGCAAGGACGGCAAGAACGCGTTCGACTCGGTGA
TCCGCCAGGGCCGCAAGCGGATGGCGGAAGGCGCGTGGGTCATCATGTTCCCCGAAGGCACGCGCACGCCGGTCGGCGGG
CAGGGCAAGTACAAGACGGGCGGCGCGCGCTTCGCGGTGGGCGCGGGCGCGCCCGTCGTGCCGATCGCGCACAACGCGGG
GCGCGTGTGGCCGCGCAACTCGTTCACGAAGTACCCCGGCACCGTCACGGTGTCGATCGGCAAGCCGATCGACACGCAAG
GCCTCACCCCCGATCAACTGAACGAACGCGTCGAAAACTGGATCGAAGCGGAAATGCGCCGCATCGATCCGGACGCGTAC
CGGCACGAGCGCGACGGCGCACGCGGCGCCGTCCGAGCGTCCGACGCCGCGCGTTCCTGA

Upstream 100 bases:

>100_bases
CGTGCACGACGACCTGCGCGCGTTCGCGCTCGATTTCCTTTCCAAAGAACACGAGTGATGCCCACCCGCGCGCATCCTCC
CTCACCGTAACGTCACGCCG

Downstream 100 bases:

>100_bases
AGTCAAGCGAGTTTCACCCATTGCGCACTGCCAAACGAAGCGAACTGATGCCGAAGCGTCCCAGGCCACGGCCGGCCGTC
GTGGCTCTCGATCACCGCCA

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT; Phosphatidic acid synthase; PA synthase [H]

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MRFVRSLLLLVYFVVYTVPYATACFIAFPFMRPNARYWMAVGWCKSTLFVARWLNGIRYRIEGYENLPDGPAVLLPKHQS
AWETIALPALMPKPLCYVFKRELLYVPFFGWALGMLHMVHINRKDGKNAFDSVIRQGRKRMAEGAWVIMFPEGTRTPVGG
QGKYKTGGARFAVGAGAPVVPIAHNAGRVWPRNSFTKYPGTVTVSIGKPIDTQGLTPDQLNERVENWIEAEMRRIDPDAY
RHERDGARGAVRASDAARS

Sequences:

>Translated_259_residues
MRFVRSLLLLVYFVVYTVPYATACFIAFPFMRPNARYWMAVGWCKSTLFVARWLNGIRYRIEGYENLPDGPAVLLPKHQS
AWETIALPALMPKPLCYVFKRELLYVPFFGWALGMLHMVHINRKDGKNAFDSVIRQGRKRMAEGAWVIMFPEGTRTPVGG
QGKYKTGGARFAVGAGAPVVPIAHNAGRVWPRNSFTKYPGTVTVSIGKPIDTQGLTPDQLNERVENWIEAEMRRIDPDAY
RHERDGARGAVRASDAARS
>Mature_259_residues
MRFVRSLLLLVYFVVYTVPYATACFIAFPFMRPNARYWMAVGWCKSTLFVARWLNGIRYRIEGYENLPDGPAVLLPKHQS
AWETIALPALMPKPLCYVFKRELLYVPFFGWALGMLHMVHINRKDGKNAFDSVIRQGRKRMAEGAWVIMFPEGTRTPVGG
QGKYKTGGARFAVGAGAPVVPIAHNAGRVWPRNSFTKYPGTVTVSIGKPIDTQGLTPDQLNERVENWIEAEMRRIDPDAY
RHERDGARGAVRASDAARS

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the 2 position. This enzyme can utilize either acyl-CoA or acyl-ACP as the fatty acyl donor [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=197, Percent_Identity=28.4263959390863, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI15100175, Length=197, Percent_Identity=28.4263959390863, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI6041665, Length=168, Percent_Identity=29.1666666666667, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1789395, Length=185, Percent_Identity=28.1081081081081, Blast_Score=74, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17564032, Length=183, Percent_Identity=30.6010928961749, Blast_Score=87, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6320151, Length=183, Percent_Identity=28.9617486338798, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI281364648, Length=195, Percent_Identity=28.2051282051282, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24582856, Length=195, Percent_Identity=28.2051282051282, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24582854, Length=195, Percent_Identity=28.2051282051282, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641614, Length=192, Percent_Identity=25.5208333333333, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24641612, Length=192, Percent_Identity=25.5208333333333, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 29236; Mature: 29236

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFVRSLLLLVYFVVYTVPYATACFIAFPFMRPNARYWMAVGWCKSTLFVARWLNGIRYR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHEEE
IEGYENLPDGPAVLLPKHQSAWETIALPALMPKPLCYVFKRELLYVPFFGWALGMLHMVH
ECCCCCCCCCCEEEECCCCCCHHHHCCHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHE
INRKDGKNAFDSVIRQGRKRMAEGAWVIMFPEGTRTPVGGQGKYKTGGARFAVGAGAPVV
ECCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCCEE
PIAHNAGRVWPRNSFTKYPGTVTVSIGKPIDTQGLTPDQLNERVENWIEAEMRRIDPDAY
EEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHH
RHERDGARGAVRASDAARS
HHHCCCCCCCEECCCCCCC
>Mature Secondary Structure
MRFVRSLLLLVYFVVYTVPYATACFIAFPFMRPNARYWMAVGWCKSTLFVARWLNGIRYR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHEEE
IEGYENLPDGPAVLLPKHQSAWETIALPALMPKPLCYVFKRELLYVPFFGWALGMLHMVH
ECCCCCCCCCCEEEECCCCCCHHHHCCHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHE
INRKDGKNAFDSVIRQGRKRMAEGAWVIMFPEGTRTPVGGQGKYKTGGARFAVGAGAPVV
ECCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCCEE
PIAHNAGRVWPRNSFTKYPGTVTVSIGKPIDTQGLTPDQLNERVENWIEAEMRRIDPDAY
EEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHH
RHERDGARGAVRASDAARS
HHHCCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1557036; 9278503 [H]